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PUBLICACIONES

 

 

spacerTrabajos Publicados por Pilar López Larrubia
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  1. Ruiz-García, C.; Lassaletta, L.; López-Larrubia, P.; Varela-Nieto, I.; Murillo-Cuesta, S. "Tumors of the nervous system and hearing loss: Beyond vestibular schwannomas.". Hear Res. 447(): 109012. (2024). (PMID: 38703433).
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  2. Ackerstaff, E.; López-Larrubia, P. "Editorial: Differentiating brain cancers and glioblastoma through imaging methodologies.". Front Oncol. 13(): 1351874. (2023). (PMID: 38164194).
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  3. Satrustegui, J.; Larrubia, P.L.; Rodrigues, T.B.; Choi, I.Y.; McKenna, M.C. "A tribute to Sebastián Cerdán and his key contributions to brain metabolism.". J Neurochem. (): . (2023). (PMID: 37169729).
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  4. Ferreira, V.; Folgueira, C.; García-Altares, M.; Guillén, M.; Ruíz-Rosario, M.; DiNunzio, G.; Garcia-Martinez, I.; Alen, R.; Bookmeyer, C.; Jones, J.G.; Cigudosa, J.C.; López-Larrubia, P.; Correig-Blanchar, X.; Davis, R.J.; Sabio, G.; Rada, P.; Valverde, Á.M. "Hypothalamic JNK1-hepatic fatty acid synthase axis mediates a metabolic rewiring that prevents hepatic steatosis in male mice treated with olanzapine via intraperitoneal: Additional effects of PTP1B inhibition.". Redox Biol. 63(): 102741. (2023). (PMID: 37230004).
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  5. Guadilla, I.; González, S.; Cerdán, S.; Lizarbe, B.; López-Larrubia, P. "Magnetic resonance imaging to assess the brain response to fasting in glioblastoma-bearing rats as a model of cancer anorexia.". Cancer Imaging. 23(1): 36. (2023). (PMID: 37038232).
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  6. López-Larrubia, P.; Santone, A. "Editorial: Incorporation of reporting and data systems into cancer radiology.". Front Oncol. 13(): 1171171. (2023). (PMID: 37007155).
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  7. Campillo, B.W.; Galguera, D.; Cerdan, S.; López-Larrubia, P.; Lizarbe, B. "Short-term high-fat diet alters the mouse brain magnetic resonance imaging parameters consistently with neuroinflammation on males and metabolic rearrangements on females. A pre-clinical study with an optimized selection of linear mixed-effects models.". Front Neurosci. 16(): 1025108. (2022). (PMID: 36507349).
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  8. Ferreira, V.; Folgueira, C.; Guillén, M.; Zubiaur, P.; Navares, M.; Sarsenbayeva, A.; López-Larrubia, P.; Eriksson, J.W.; Pereira, M.J.; Abad-Santos, F.; Sabio, G.; Rada, P.; Valverde, Á.M. "Modulation of hypothalamic AMPK phosphorylation by olanzapine controls energy balance and body weight.". Metabolism. 137(): 155335. (2022). (PMID: 36272468).
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  9. Costa-Pereira, J.T.; Oliveira, R.; Guadilla, I.; Guillén, M.J.; Tavares, I.; López-Larrubia, P. "Neuroimaging uncovers neuronal and metabolic changes in pain modulatory brain areas in a rat model of chemotherapy-induced neuropathy - MEMRI and ex vivo spectroscopy studies.". Brain Res Bull. (): . (2022). (PMID: 36328144).
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  10. Arias-Ramos, N.; Ibarra, L.E.; Serrano-Torres, M.; Yagüe, B.; Caverzán, M.D.; Chesta, C.A.; Palacios, R.E.; López-Larrubia, P. "Iron Oxide Incorporated Conjugated Polymer Nanoparticles for Simultaneous Use in Magnetic Resonance and Fluorescent Imaging of Brain Tumors.". Pharmaceutics. 13(8): . (2021). (PMID: 34452219).
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  11. Guadilla, I.; Lizarbe, B.; Barrios, L.; Cerdán, S.; López-Larrubia, P. "Integrative analysis of physiological responses to high fat feeding with diffusion tensor images and neurochemical profiles of the mouse brain.". Int J Obes (Lond). (): . (2021). (PMID: 33574566).
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  12. Lizarbe, B.; Campillo, B.; Guadilla, I.; López-Larrubia, P.; Cerdán, S. "Magnetic resonance assessment of the cerebral alterations associated with obesity development.". J. Cereb. Blood Flow Metab.. (): 271678X20941263. (2020). (PMID: 32703110).
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  13. Ibarra, L.E.; Beaugé, L.; Arias-Ramos, N.; Rivarola, V.A.; Chesta, C.A.; López-Larrubia, P.; Palacios, R.E. "Trojan horse monocyte-mediated delivery of conjugated polymer nanoparticles for improved photodynamic therapy of glioblastoma.". Nanomedicine (Lond). 15(17): 1687-1707. (2020). (PMID: 32689873).
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  14. Negri, V.; Pacheco-Torres, J.; Calle, D.; López-Larrubia, P. "Carbon Nanotubes in Biomedicine.". Top Curr Chem (Cham). 378(1): 15. (2020). (PMID: 31938922).
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  15. Silva, F.; Paulo, A.; Pallier, A.; Même, S.; Tóth, É.; Gano, L.; Marques, F.; Geraldes, C.F.G.C.; Castro, M.M.C.A.; Cardoso, A.M.; Jurado, A.S.; López-Larrubia, P.; Lacerda, S.; Campello, M.P.C. "Dual Imaging Gold Nanoplatforms for Targeted Radiotheranostics.". Materials (Basel). 13(3): . (2020). (PMID: 31978954).
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  16. Escoll, M.; Lastra, D.; Pajares, M.; Robledinos-Antón, N.; Rojo, A.I.; Fernández-Ginés, R.; Mendiola, M.; Martínez-Marín, V.; Esteban, I.; López-Larrubia, P.; Gargini, R.; Cuadrado, A. "Transcription factor NRF2 uses the Hippo pathway effector TAZ to induce tumorigenesis in glioblastomas.". Redox Biol. 30(): 101425. (2020). (PMID: 31918259).
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  17. Lizarbe, B.; Fernández-Pérez, A.; Caz, V.; Largo, C.; Vallejo, M.; López-Larrubia, P.; Cerdán, S. "Systemic Glucose Administration Alters Water Diffusion and Microvascular Blood Flow in Mouse Hypothalamic Nuclei - An fMRI Study.". Front Neurosci. 13(): 921. (2019). (PMID: 31551685).
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  18. Benítez, A.; Lizarbe, B.; Guadilla, I.; López-Larrubia, P.; Lago-Fernández, L.F.; Cerdán, S.; Sánchez-Montañés, M. "Cerebral hunger maps in rodents and humans by diffusion weighted MRI.". Appetite. (): 104333. (2019). (PMID: 31252030).
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  19. Gandía-González, M.L.; Cerdán, S.; Barrios, L.; López-Larrubia, P.; Feijoó, P.G.; Palpan, A.; Roda, J.M.; Solivera, J. "Assessment of Overall Survival in Glioma Patients as Predicted by Metabolomic Criteria.". Front Oncol. 9(): 328. (2019). (PMID: 31134147).
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  20. Guadilla, I.; Calle, D.; López-Larrubia, P. "Diffusion-Weighted Magnetic Resonance Imaging.". Methods Mol. Biol.. 1718(): 89-8101. (2018). (PMID: 29341004).
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  21. López-Larrubia, P. "Dynamic Susceptibility Contrast MRI in Small Animals.". Methods Mol. Biol.. 1718(): 41-57. (2018). (PMID: 29341001).
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  22. Oliveira, R.M.R.; Guadilla, I.; López-Larrubia, P. "Functional Diffusion Magnetic Resonance Imaging.". Methods Mol. Biol.. 1718(): 135-147. (2018). (PMID: 29341007).
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  23. Zhou, H.; Arias-Ramos, N.; López-Larrubia, P.; Mason, R.P.; Cerdán, S.; Pacheco-Torres, J. "Oxygenation Imaging by Nuclear Magnetic Resonance Methods.". Methods Mol. Biol.. 1718(): 297-313. (2018). (PMID: 29341016).
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  24. Righi, V.; García-Martín, M.L.; Mucci, A.; Schenetti, L.; Tugnoli, V.; Lopez-Larrubia, P.; Cerdán, S. "Spatially Resolved Bioenergetic and Genetic Reprogramming Through the Brain of Rats Bearing Implanted C6 Gliomas As Detected by Multinuclear High-Resolution Magic Angle Spinning and Genomic Analysis.". J. Proteome Res.. 17(9): 2953-2962. (2018). (PMID: 30129764).
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  25. Lizarbe, B.; López-Larrubia, P.; Cerdán, S. "fDWI Evaluation of Hypothalamic Appetite Regulation Pathways in Mice Genetically Deficient in Leptin or Neuropeptide Y.". Neurochem. Res.. 40(12): 2628-2638. (2015). (PMID: 25968479).
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  26. Pacheco-Torres, J.; Mukherjee, N.; Walko, M.; López-Larrubia, P.; Ballesteros, P.; Cerdan, S.; Kocer, A. "Image guided drug release from pH-sensitive Ion channel-functionalized stealth liposomes into an in vivo glioblastoma model.". Nanomedicine. 11(6): 1345-1354. (2015). (PMID: 25888277).
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  27. Pérez-Carro, R.; Cauli, O.; López-Larrubia, P. "Multiparametric magnetic resonance in the assessment of the gender differences in a high-grade glioma rat model.". EJNMMI Res. 4(1): 44. (2014). (PMID: 26116110).
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  28. Cauli, O.; González-Usano, A.; Cabrera-Pastor, A.; Gimenez-Garzó, C.; López-Larrubia, P.; Ruiz-Sauri, A.; Hernández-Rabaza, V.; Duszczyk, M.; Malek, M.; Lazarewicz, J.W.; Carratalá, A.; Urios, A.; Miguel, A.; Torregrosa, I.; Carda, C.; Montoliu, C.; Felipo, V. "Blocking NMDA receptors delays death in rats with acute liver failure by dual protective mechanisms in kidney and brain.". Neuromolecular Med.. 16(2): 360-375. (2014). (PMID: 24338618).
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  29. García-Palmero, I.; López-Larrubia, P.; Cerdán, S.; Villalobo, A. "Nuclear magnetic resonance imaging of tumour growth and neovasculature performance in vivo reveals Grb7 as a novel antiangiogenic target.". NMR Biomed. 26(9): 1059-1069. (2013). (PMID: 23348935).
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  30. Lizarbe, B.; Benitez, A.; Peláez Brioso, G.A.; Sánchez-Montañés, M.; López-Larrubia, P.; Ballesteros, P.; Cerdán, S. "Hypothalamic metabolic compartmentation during appetite regulation as revealed by magnetic resonance imaging and spectroscopy methods.". Front Neuroenergetics. 5(): 6. (2013). (PMID: 23781199).
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  31. Belmar-Lopez, C.; Mendoza, G.; Oberg, D.; Burnet, J.; Simon, C.; Cervello, I.; Iglesias, M.; Ramirez, J.C.; Lopez-Larrubia, P.; Quintanilla, M.; Martin-Duque, P. "Tissue-derived mesenchymal stromal cells used as vehicles for anti-tumor therapy exert different in vivo effects on migration capacity and tumor growth.". BMC Med. 11(): 139. (2013). (PMID: 23710709).
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  32. Lizarbe, B.; Benítez, A.; Sánchez-Montañés, M.; Lago-Fernández, L.F.; Garcia-Martin, M.L.; López-Larrubia, P.; Cerdán, S. "Imaging hypothalamic activity using diffusion weighted magnetic resonance imaging in the mouse and human brain.". Neuroimage. 64(): 448-457. (2013). (PMID: 23000787).
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  33. Metelo, A.M.; Pérez-Carro, R.; Castro, M.M.; López-Larrubia, P. "VO(dmpp)2 normalizes pre-diabetic parameters as assessed by in vivo magnetic resonance imaging and spectroscopy.". J. Inorg. Biochem.. 115(): 44-49. (2012). (PMID: 22922310).
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  34. Mansouri, M.T.; Naghizadeh, B.; López-Larrubia, P.; Cauli, O. "Gender-dependent behavioural impairment and brain metabolites in young adult rats after short term exposure to lead acetate.". Toxicol. Lett.. 210(1): 15-23. (2012). (PMID: 22285975).
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  35. Borges, A.R.; Lopez-Larrubia, P.; Marques, J.B.; Cerdan, S.G. "MR imaging features of high-grade gliomas in murine models: how they compare with human disease, reflect tumor biology, and play a role in preclinical trials.". AJNR Am J Neuroradiol. 33(1): 24-36. (2012). (PMID: 22194368).
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  36. Fernández-Trillo, F.; Pacheco-Torres, J.; Correa, J.; Ballesteros, P.; Lopez-Larrubia, P.; Cerdán, S.; Riguera, R.; Fernandez-Megia, E. "Dendritic MRI contrast agents: an efficient prelabeling approach based on CuAAC.". Biomacromolecules. 12(8): 2902-2907. (2011). (PMID: 21728317).
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  37. Fernández, M.; Manso, R.; Bernaldo de Quirós, F.; Bernáldez, F.; López, P.; Martín-Duce, A.; Alemany, S. "Involvement of Cot activity in the proliferation of ALCL lymphoma cells.". Biochem. Biophys. Res. Commun.. 411(4): 655-660. (2011). (PMID: 21741362).
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  38. Pacheco-Torres, J.; Calle, D.; Lizarbe, B.; Negri, V.; Ubide, C.; Fayos, R.; Larrubia, P.L.; Ballesteros, P.; Cerdan, S. "Environmentally sensitive paramagnetic and diamagnetic contrast agents for nuclear magnetic resonance imaging and spectroscopy.". Curr Top Med Chem. 11(1): 115-130. (2011). (PMID: 20809891).
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  39. López-Larrubia, P.; Cauli, O. "Alterations of apparent diffusion coefficient (ADC) in the brain of rats chronically exposed to lead acetate.". Toxicology. 281(1-3): 1-6. (2011). (PMID: 21215787).
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  40. Cauli, O.; López-Larrubia, P.; Rodrigo, R.; Agusti, A.; Boix, J.; Nieto-Charques, L.; Cerdán, S.; Felipo, V. "Brain region-selective mechanisms contribute to the progression of cerebral alterations in acute liver failure in rats.". Gastroenterology. 140(2): 638-645. (2011). (PMID: 20977905).
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  41. García-Martín, M.L.; Adrados, M.; Ortega, M.P.; Fernández González, I.; López-Larrubia, P.; Viaño, J.; García-Segura, J.M. "Quantitative (1) H MR spectroscopic imaging of the prostate gland using LCModel and a dedicated basis-set: correlation with histologic findings.". Magn Reson Med. 65(2): 329-339. (2011). (PMID: 20939087).
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  42. Pacheco-Torres, J.; López-Larrubia, P.; Ballesteros, P.; Cerdán, S. "Imaging tumor hypoxia by magnetic resonance methods.". NMR Biomed. 24(1): 1-16. (2011). (PMID: 21259366).
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  43. Moros, M.; Pelaz, B.; López-Larrubia, P.; García-Martin, M.L.; Grazú, V.; de la Fuente, J.M. "Engineering biofunctional magnetic nanoparticles for biotechnological applications.". Nanoscale. 2(9): 1746-1755. (2010). (PMID: 20676420).
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  44. Negri, V.; Cerpa, A.; López-Larrubia, P.; Nieto-Charques, L.; Cerdán, S.; Ballesteros, P. "Nanotubular paramagnetic probes as contrast agents for magnetic resonance imaging based on the diffusion tensor.". Angew. Chem. Int. Ed. Engl.. 49(10): 1813-1815. (2010). (PMID: 20140928).
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  45. Rodrigues, T.B.; López-Larrubia, P.; Cerdán, S. "Redox dependence and compartmentation of [13C]pyruvate in the brain of deuterated rats bearing implanted C6 gliomas.". J. Neurochem.. 109 Suppl 1(): 237-245. (2009). (PMID: 19393033).
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  46. Delgado, T.C.; Pinheiro, D.; Caldeira, M.; Castro, M.M.; Geraldes, C.F.; López-Larrubia, P.; Cerdán, S.; Jones, J.G. "Sources of hepatic triglyceride accumulation during high-fat feeding in the healthy rat.". NMR Biomed. 22(3): 310-317. (2009). (PMID: 19012281).
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  47. Rodríguez, C.; López, P.; Pozo, M.; Duce, A.M.; López-Pelaéz, M.; Fernández, M.; Alemany, S. "COX2 expression and Erk1/Erk2 activity mediate Cot-induced cell migration.". Cell. Signal.. 20(9): 1625-1631. (2008). (PMID: 18572386).
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  48. Torres, S.; Prata, M.I.; Santos, A.C.; André, J.P.; Martins, J.A.; Helm, L.; Tóth, E.; García-Martín, M.L.; Rodrigues, T.B.; López-Larrubia, P.; Cerdán, S.; Geraldes, C.F. "Gd(III)-EPTPAC16, a new self-assembling potential liver MRI contrast agent: in vitro characterization and in vivo animal imaging studies.". NMR Biomed. 21(4): 322-336. (2008). (PMID: 17694538).
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  49. Cauli, O.; López-Larrubia, P.; Rodrigues, T.B.; Cerdán, S.; Felipo, V. "Magnetic resonance analysis of the effects of acute ammonia intoxication on rat brain. Role of NMDA receptors.". J. Neurochem.. 103(4): 1334-1343. (2007). (PMID: 17727627).
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  50. Soler-Padrós, J.; Pérez-Mayoral, E.; Domínguez, L.; López-Larrubia, P.; Soriano, E.; Marco-Contelles, J.L.; Cerdan, S.; Ballesteros, P. "Novel generation of pH indicators for proton magnetic resonance spectroscopic imaging.". J. Med. Chem.. 50(18): 4539-4542. (2007). (PMID: 17691761).
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  51. Provent, P.; Benito, M.; Hiba, B.; Farion, R.; López-Larrubia, P.; Ballesteros, P.; Rémy, C.; Segebarth, C.; Cerdán, S.; Coles, J.A.; García-Martín, M.L. "Serial in vivo spectroscopic nuclear magnetic resonance imaging of lactate and extracellular pH in rat gliomas shows redistribution of protons away from sites of glycolysis.". Cancer Res.. 67(16): 7638-7645. (2007). (PMID: 17699768).
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  52. Pascual, J.M.; Solivera, J.; Prieto, R.; Barrios, L.; López-Larrubia, P.; Cerdán, S.; Roda, J.M. "Time course of early metabolic changes following diffuse traumatic brain injury in rats as detected by (1)H NMR spectroscopy.". J. Neurotrauma. 24(6): 944-959. (2007). (PMID: 17600512).
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  53. Prata, M.I.; Santos, A.C.; Torres, S.; André, J.P.; Martins, J.A.; Neves, M.; García-Martín, M.L.; Rodrigues, T.B.; López-Larrubia, P.; Cerdán, S.; Geraldes, C.F. "Targeting of lanthanide(III) chelates of DOTA-type glycoconjugates to the hepatic asyaloglycoprotein receptor: cell internalization and animal imaging studies.". Contrast Media Mol Imaging. 1(6): 246-258. (2007). (PMID: 17191765).
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  54. Rodríguez, E.; Roig, A.; Molins, E.; Arús, C.; Quintero, M.R.; Cabañas, M.E.; Cerdán, S.; Lopez-Larrubia, P.; Sanfeliu, C. "In vitro characterization of an Fe(8) cluster as potential MRI contrast agent.". NMR Biomed. 18(5): 300-307. (2005). (PMID: 15912577).
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  55. Mayoral, E.P.; García-Amo, M.; López, P.; Soriano, E.; Cerdán, S.; Ballesteros, P. "A novel series of complexones with bis- or biazole structure as mixed ligands of paramagnetic contrast agents for MRI.". Bioorg. Med. Chem.. 11(24): 5555-5567. (2003). (PMID: 14642600).
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  56. Gándara, M.L.; López, P.; Hernando, R.; Castaño, J.G.; Alemany, S. "The COOH-terminal domain of wild-type Cot regulates its stability and kinase specific activity.". Mol. Cell. Biol.. 23(20): 7377-7390. (2003). (PMID: 14517305).
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