Santibañez, J.F.; Quintanilla, M.; Bernabeu, C. "TGF-β/TGF-β receptor system and its role in physiological and pathological conditions.". Clin. Sci.. 121(6): 233-251. (2011). (PMID: 21615335).
Latorre-Romero, C.; Marin-Yaseli, M.R.; Belmar-Lopez, C.; del Moral, R.; Marijuan, P.C.; Quintanilla, M.; Martin-Duque, P. "Using living cells to transport therapeutic genes for cancer treatment.". Clin Transl Oncol. 13(1): 10-17. (2011). (PMID: 21239350).
Pérez-Gómez, E.; Del Castillo, G.; Juan Francisco, S.; López-Novoa, J.M.; Bernabéu, C.; Quintanilla, M. "The role of the TGF-β coreceptor endoglin in cancer.". ScientificWorldJournal. 10(): 2367-2384. (2010). (PMID: 21170488).
Santibanez, J.F.; Pérez-Gómez, E.; Fernandez-L, A.; Garrido-Martin, E.M.; Carnero, A.; Malumbres, M.; Vary, C.P.; Quintanilla, M.; Bernabéu, C. "The TGF-beta co-receptor endoglin modulates the expression and transforming potential of H-Ras.". Carcinogenesis. 31(12): 2145-2154. (2010). (PMID: 20884686).
Santibáñez, J.F.; Koci, J.; Fabra, A.; Cano, A.; Quintanilla, M. "Rac1 modulates TGF-beta1-mediated epithelial cell plasticity and MMP9 production in transformed keratinocytes.". FEBS Lett.. 584(11): 2305-2310. (2010). (PMID: 20353788).
Hinojar-Gutiérrez, A.; Fernández-Contreras, M.E.; Alvarez-Carrillo, S.; Quintanilla, M.; Gamallo, C. "Role of intratumoral lymphatic vessels in the lymph node dissemination of laryngopharyngeal squamous cell carcinoma.". Head Neck. 32(6): 757-762. (2010). (PMID: 19862828).
Peerlinck, I.; Merron, A.; Baril, P.; Conchon, S.; Martin-Duque, P.; Hindorf, C.; Burnet, J.; Quintanilla, M.; Hingorani, M.; Iggo, R.; Lemoine, N.R.; Harrington, K.; Vassaux, G. "Targeted radionuclide therapy using a Wnt-targeted replicating adenovirus encoding the Na/I symporter.". Clin. Cancer Res.. 15(21): 6595-6601. (2009). (PMID: 19861465).
Bernabeu, C.; Lopez-Novoa, J.M.; Quintanilla, M. "The emerging role of TGF-beta superfamily coreceptors in cancer.". Biochim. Biophys. Acta. 1792(10): 954-973. (2009). (PMID: 19607914).
Blanco, F.J.; Grande, M.T.; Langa, C.; Oujo, B.; Velasco, S.; Rodriguez-Barbero, A.; Perez-Gomez, E.; Quintanilla, M.; López-Novoa, J.M.; Bernabeu, C. "S-endoglin expression is induced in senescent endothelial cells and contributes to vascular pathology.". Circ. Res.. 103(12): 1383-1392. (2008). (PMID: 18974388).
Müller, D.; Trunk, G.; Sichelstiel, A.; Zettlitz, K.A.; Quintanilla, M.; Kontermann, R.E. "Murine endoglin-specific single-chain Fv fragments for the analysis of vascular targeting strategies in mice.". J. Immunol. Methods. 339(1): 90-98. (2008). (PMID: 18790696).
Montiel-Equihua, C.A.; Martín-Duque, P.; de la Vieja, A.; Quintanilla, M.; Burnet, J.; Vassaux, G.; Lemoine, N.R. "Targeting sodium/iodide symporter gene expression for estrogen-regulated imaging and therapy in breast cancer.". Cancer Gene Ther.. 15(7): 465-473. (2008). (PMID: 18421306).
Romero, D.; Iglesias, M.; Vary, C.P.; Quintanilla, M. "Functional blockade of Smad4 leads to a decrease in beta-catenin levels and signaling activity in human pancreatic carcinoma cells.". Carcinogenesis. 29(5): 1070-1076. (2008). (PMID: 18310088).
Belmar-Lopez, C.; Mancheno-Corvo, P.; Saornil, M.A.; Baril, P.; Vassaux, G.; Quintanilla, M.; Martin-Duque, P. "Uveal vs. cutaneous melanoma. Origins and causes of the differences.". Clin Transl Oncol. 10(3): 137-142. (2008). (PMID: 18321815).
Merron, A.; Peerlinck, I.; Martin-Duque, P.; Burnet, J.; Quintanilla, M.; Mather, S.; Hingorani, M.; Harrington, K.; Iggo, R.; Vassaux, G. "SPECT/CT imaging of oncolytic adenovirus propagation in tumours in vivo using the Na/I symporter as a reporter gene.". Gene Ther.. 14(24): 1731-1738. (2007). (PMID: 17960161).
Pérez-Gómez, E.; Villa-Morales, M.; Santos, J.; Fernández-Piqueras, J.; Gamallo, C.; Dotor, J.; Bernabéu, C.; Quintanilla, M. "A role for endoglin as a suppressor of malignancy during mouse skin carcinogenesis.". Cancer Res.. 67(21): 10268-10277. (2007). (PMID: 17974968).
Villa-Morales, M.; Santos, J.; Pérez-Gómez, E.; Quintanilla, M.; Fernández-Piqueras, J. "A role for the Fas/FasL system in modulating genetic susceptibility to T-cell lymphoblastic lymphomas.". Cancer Res.. 67(11): 5107-5116. (2007). (PMID: 17545588).
Hinojar-Gutiérrez, A.; Fernández-Contreras, M.E.; González-González, R.; Fernández-Luque, M.J.; Hinojar-Arzadún, A.; Quintanilla, M.; Gamallo, C. "Intratumoral lymphatic vessels and VEGF-C expression are predictive factors of lymph node relapse in T1-T4 N0 laryngopharyngeal squamous cell carcinoma.". Ann. Surg. Oncol.. 14(1): 248-257. (2007). (PMID: 17066224).
Martín-Villar, E.; Megías, D.; Castel, S.; Yurrita, M.M.; Vilaró, S.; Quintanilla, M. "Podoplanin binds ERM proteins to activate RhoA and promote epithelial-mesenchymal transition.". J. Cell. Sci.. 119(Pt 21): 4541-4553. (2006). (PMID: 17046996).
Pons, M.; Quintanilla, M. "Molecular biology of malignant melanoma and other cutaneous tumors.". Clin Transl Oncol. 8(7): 466-474. (2006). (PMID: 16870533).
Martín-Duque, P.; Quintanilla, M.; McNeish, I.; Lopes, R.; Romero, J.; Romero, D.; Lemoine, N.R.; Ramón y Cajal, S.; Vassaux, G. "Caspase-1 as a radio- and chemo-sensitiser in vitro and in vivo.". Int. J. Mol. Med.. 17(5): 841-847. (2006). (PMID: 16596269).
Pons, M.; Cigudosa, J.C.; Rodríguez-Perales, S.; Bella, J.L.; González, C.; Gamallo, C.; Quintanilla, M. "Chromosomal instability and phenotypic plasticity during the squamous-spindle carcinoma transition: association of a specific T(14;15) with malignant progression.". Oncogene. 24(51): 7608-7618. (2005). (PMID: 16007119).
Pérez-Gómez, E.; Eleno, N.; López-Novoa, J.M.; Ramirez, J.R.; Velasco, B.; Letarte, M.; Bernabéu, C.; Quintanilla, M. "Characterization of murine S-endoglin isoform and its effects on tumor development.". Oncogene. 24(27): 4450-4461. (2005). (PMID: 15806144).
Martín-Villar, E.; Scholl, F.G.; Gamallo, C.; Yurrita, M.M.; Muñoz-Guerra, M.; Cruces, J.; Quintanilla, M. "Characterization of human PA2.26 antigen (T1alpha-2, podoplanin), a small membrane mucin induced in oral squamous cell carcinomas.". Int. J. Cancer. 113(6): 899-910. (2005). (PMID: 15515019).
Muñoz-Guerra, M.F.; Marazuela, E.G.; Martín-Villar, E.; Quintanilla, M.; Gamallo, C. "Prognostic significance of intratumoral lymphangiogenesis in squamous cell carcinoma of the oral cavity.". Cancer. 100(3): 553-560. (2004). (PMID: 14745872).
Quintanilla, M.; Ramirez, J.R.; Pérez-Gómez, E.; Romero, D.; Velasco, B.; Letarte, M.; López-Novoa, J.M.; Bernabéu, C. "Expression of the TGF-beta coreceptor endoglin in epidermal keratinocytes and its dual role in multistage mouse skin carcinogenesis.". Oncogene. 22(38): 5976-5985. (2003). (PMID: 12955076).
Peinado, H.; Quintanilla, M.; Cano, A. "Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions.". J. Biol. Chem.. 278(23): 21113-21123. (2003). (PMID: 12665527).
Santibáñez, J.F.; Guerrero, J.; Quintanilla, M.; Fabra, A.; Martínez, J. "Transforming growth factor-beta1 modulates matrix metalloproteinase-9 production through the Ras/MAPK signaling pathway in transformed keratinocytes.". Biochem. Biophys. Res. Commun.. 296(2): 267-273. (2002). (PMID: 12163012).
Santibáñez, J.F.; Quintanilla, M.; Martínez, J. "TGF-beta(1) and Smad4 overexpression induce a less invasive phenotype in highly invasive spindle carcinoma cells.". FEBS Lett.. 520(1-3): 171-176. (2002). (PMID: 12044892).
Pálmer, H.G.; González-Sancho, J.M.; Espada, J.; Berciano, M.T.; Puig, I.; Baulida, J.; Quintanilla, M.; Cano, A.; de Herreros, A.G.; Lafarga, M.; Muñoz, A. "Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling.". J. Cell Biol.. 154(2): 369-387. (2001). (PMID: 11470825).
Santibáñez, J.F.; Quintanilla, M.; Martínez, J. "Genistein and curcumin block TGF-beta 1-induced u-PA expression and migratory and invasive phenotype in mouse epidermal keratinocytes.". Nutr Cancer. 37(1): 49-54. (2000). (PMID: 10965519).
Scholl, F.G.; Gamallo, C.; Quintanilla, M. "Ectopic expression of PA2.26 antigen in epidermal keratinocytes leads to destabilization of adherens junctions and malignant progression.". Lab. Invest.. 80(11): 1749-1759. (2000). (PMID: 11092535).
Iglesias, M.; Frontelo, P.; Gamallo, C.; Quintanilla, M. "Blockade of Smad4 in transformed keratinocytes containing a Ras oncogene leads to hyperactivation of the Ras-dependent Erk signalling pathway associated with progression to undifferentiated carcinomas.". Oncogene. 19(36): 4134-4145. (2000). (PMID: 10962574).
Santibáñez, J.F.; Iglesias, M.; Frontelo, P.; Martínez, J.; Quintanilla, M. "Involvement of the Ras/MAPK signaling pathway in the modulation of urokinase production and cellular invasiveness by transforming growth factor-beta(1) in transformed keratinocytes.". Biochem. Biophys. Res. Commun.. 273(2): 521-527. (2000). (PMID: 10873638).
Scholl, F.G.; Gamallo, C.; Vilaró, S.; Quintanilla, M. "Identification of PA2.26 antigen as a novel cell-surface mucin-type glycoprotein that induces plasma membrane extensions and increased motility in keratinocytes.". J. Cell. Sci.. 112 ( Pt 24)(): 4601-4613. (1999). (PMID: 10574709).
Martin-Duque, P.; Sánchez-Prieto, R.; Romero, J.; Martinez-Lamparero, A.; Cebrian-Sagarriga, S.; Guinea-Viniegra, J.; Dominguez, C.; Lleonart, M.; Cano, A.; Quintanilla, M.; Ramón Y Cajal, S. "In vivo radiosensitizing effect of the adenovirus E1A gene in murine and human malignant tumors.". Int. J. Oncol.. 15(6): 1163-1168. (1999). (PMID: 10568823).
Duque, P.M.; Alonso, C.; Sánchez-Prieto, R.; Lleonart, M.; Martínez, C.; de Buitrago, G.G.; Cano, A.; Quintanilla, M.; Ramon y Cajal, S. "Adenovirus lacking the 19-kDa and 55-kDa E1B genes exerts a marked cytotoxic effect in human malignant cells.". Cancer Gene Ther.. 6(6): 554-563. (1999). (PMID: 10608352).
Santibáñez, J.F.; Frontelo, P.; Iglesias, M.; Martínez, J.; Quintanilla, M. "Urokinase expression and binding activity associated with the transforming growth factor beta1-induced migratory and invasive phenotype of mouse epidermal keratinocytes.". J. Cell. Biochem.. 74(1): 61-73. (1999). (PMID: 10381262).
Sanchez-Prieto, R.; Quintanilla, M.; Cano, A.; Lleonart, M.; Martin, P.; Ramon y Cajal, S. "In vivo tumor suppressor effect of retrovirus-mediated gene transfer of the adenovirus E1a gene.". Adv. Exp. Med. Biol.. 451(): 79-86. (1998). (PMID: 10026854).
Frontelo, P.; González-Garrigues, M.; Vilaró, S.; Gamallo, C.; Fabra, A.; Quintanilla, M. "Transforming growth factor beta 1 induces squamous carcinoma cell variants with increased metastatic abilities and a disorganized cytoskeleton.". Exp. Cell Res.. 244(2): 420-432. (1998). (PMID: 9806792).
Llorens, A.; Rodrigo, I.; López-Barcons, L.; Gonzalez-Garrigues, M.; Lozano, E.; Vinyals, A.; Quintanilla, M.; Cano, A.; Fabra, A. "Down-regulation of E-cadherin in mouse skin carcinoma cells enhances a migratory and invasive phenotype linked to matrix metalloproteinase-9 gelatinase expression.". Lab. Invest.. 78(9): 1131-1142. (1998). (PMID: 9759657).
Sánchez-Prieto, R.; Quintanilla, M.; Martín, P.; Lleonart, M.; Cano, A.; Dotto, G.P.; Ramón y Cajal, S. "In vivo antitumor effect of retrovirus-mediated gene transfer of the adenovirus E1a gene.". Cancer Gene Ther.. 5(4): 215-224. (1998). (PMID: 9694073).
Duque, P.M.; Alonso, C.; Sanchez-Prieto, R.; Quintanilla, M.; Ramón, S.; Ramon y Cajal, S. "Antitumoral effect of E1B defective adenoviruses in human malignant cells.". Gene Ther.. 5(2): 286-287. (1998). (PMID: 9578851).
Gandarillas, A.; Scholl, F.G.; Benito, N.; Gamallo, C.; Quintanilla, M. "Induction of PA2.26, a cell-surface antigen expressed by active fibroblasts, in mouse epidermal keratinocytes during carcinogenesis.". Mol. Carcinog.. 20(1): 10-18. (1997). (PMID: 9328432).
Larcher, F.; Robles, A.I.; Duran, H.; Murillas, R.; Quintanilla, M.; Cano, A.; Conti, C.J.; Jorcano, J.L. "Up-regulation of vascular endothelial growth factor/vascular permeability factor in mouse skin carcinogenesis correlates with malignant progression state and activated H-ras expression levels.". Cancer Res.. 56(23): 5391-5396. (1996). (PMID: 8968091).
Sánchez-Prieto, R.; Quintanilla, M.; Cano, A.; Leonart, M.L.; Martin, P.; Anaya, A.; Ramón y Cajal, S. "Carcinoma cell lines become sensitive to DNA-damaging agents by the expression of the adenovirus E1A gene.". Oncogene. 13(5): 1083-1092. (1996). (PMID: 8806698).
Caulín, C.; López-Barcons, L.; Gonzáles-Garrigues, M.; Navarro, P.; Lozano, E.; Rodrigo, I.; Gamallo, C.; Cano, A.; Fabra, A.; Quintanilla, M. "Suppression of the metastatic phenotype of a mouse skin carcinoma cell line independent of E-cadherin expression and correlated with reduced Ha-ras oncogene products.". Mol. Carcinog.. 15(2): 104-114. (1996). (PMID: 8599577).
Cano, A.; Gamallo, C.; Kemp, C.J.; Benito, N.; Palacios, J.; Quintanilla, M.; Balmain, A. "Expression pattern of the cell adhesion molecules. E-cadherin, P-cadherin and alpha 6 beta 4 intergrin is altered in pre-malignant skin tumors of p53-deficient mice.". Int. J. Cancer. 65(2): 254-262. (1996). (PMID: 8567126).
Caulín, C.; Scholl, F.G.; Frontelo, P.; Gamallo, C.; Quintanilla, M. "Chronic exposure of cultured transformed mouse epidermal cells to transforming growth factor-beta 1 induces an epithelial-mesenchymal transdifferentiation and a spindle tumoral phenotype.". Cell Growth Differ.. 6(8): 1027-1035. (1995). (PMID: 8547217).
Pizarro, A.; Gamallo, C.; Benito, N.; Palacios, J.; Quintanilla, M.; Cano, A.; Contreras, F. "Differential patterns of placental and epithelial cadherin expression in basal cell carcinoma and in the epidermis overlying tumours.". Br. J. Cancer. 72(2): 327-332. (1995). (PMID: 7640213).
Pizarro, A.; Benito, N.; Navarro, P.; Palacios, J.; Cano, A.; Quintanilla, M.; Contreras, F.; Gamallo, C. "E-cadherin expression in basal cell carcinoma.". Br. J. Cancer. 69(1): 157-162. (1994). (PMID: 8286199).
Gamallo, C.; Palacios, J.; Suarez, A.; Pizarro, A.; Navarro, P.; Quintanilla, M.; Cano, A. "Correlation of E-cadherin expression with differentiation grade and histological type in breast carcinoma.". Am. J. Pathol.. 142(4): 987-993. (1993). (PMID: 7682767).
Caulín, C.; Bauluz, C.; Gandarillas, A.; Cano, A.; Quintanilla, M. "Changes in keratin expression during malignant progression of transformed mouse epidermal keratinocytes.". Exp. Cell Res.. 204(1): 11-21. (1993). (PMID: 7677983).
Larcher, F.; Bauluz, C.; Díaz-Guerra, M.; Quintanilla, M.; Conti, C.J.; Ballestín, C.; Jorcano, J.L. "Aberrant expression of the simple epithelial type II keratin 8 by mouse skin carcinomas but not papillomas.". Mol. Carcinog.. 6(2): 112-121. (1992). (PMID: 1382441).
Gómez, M.; Navarro, P.; Quintanilla, M.; Cano, A. "Expression of alpha 6 beta 4 integrin increases during malignant conversion of mouse epidermal keratinocytes: association of beta 4 subunit to the cytokeratin fraction.". Exp. Cell Res.. 201(2): 250-261. (1992). (PMID: 1379191).
Inki, P.; Gomez, M.; Quintanilla, M.; Cano, A.; Jalkanen, M. "Expression of syndecan in transformed mouse keratinocytes.". Lab. Invest.. 67(2): 225-233. (1992). (PMID: 1501448).
Gandarillas, A.; Renart, J.; Quintanilla, M. "Biochemical characterization of Artemia ras p21.". Mol. Cell. Biochem.. 112(1): 29-33. (1992). (PMID: 1513332).
Diaz-Guerra, M.; Haddow, S.; Bauluz, C.; Jorcano, J.L.; Cano, A.; Balmain, A.; Quintanilla, M. "Expression of simple epithelial cytokeratins in mouse epidermal keratinocytes harboring Harvey ras gene alterations.". Cancer Res.. 52(3): 680-687. (1992). (PMID: 1370649).
Navarro, P.; Gómez, M.; Pizarro, A.; Gamallo, C.; Quintanilla, M.; Cano, A. "A role for the E-cadherin cell-cell adhesion molecule during tumor progression of mouse epidermal carcinogenesis.". J. Cell Biol.. 115(2): 517-533. (1991). (PMID: 1918152).
Quintanilla, M.; Haddow, S.; Jonas, D.; Jaffe, D.; Bowden, G.T.; Balmain, A. "Comparison of ras activation during epidermal carcinogenesis in vitro and in vivo.". Carcinogenesis. 12(10): 1875-1881. (1991). (PMID: 1934268).
Díaz-Guerra, M.; Quintanilla, M.; Palmero, I.; Sastre, L.; Renart, J. "Differential expression of a gene highly homologous to c-ras during the development of the brine shrimp Artemia.". Biochem. Biophys. Res. Commun.. 162(2): 802-808. (1989). (PMID: 2502981).
Díaz, V.; Quintanilla, M.; Cruces, J.; Renart, J.; Sebastián, J. "Immunological relationships between Artemia RNA polymerases and between RNA polymerases II from different eukaryotic organisms.". Mol. Cell. Biochem.. 76(2): 123-131. (1987). (PMID: 3118183).
Brown, K.; Quintanilla, M.; Ramsden, M.; Kerr, I.B.; Young, S.; Balmain, A. "v-ras genes from Harvey and BALB murine sarcoma viruses can act as initiators of two-stage mouse skin carcinogenesis.". Cell. 46(3): 447-456. (1986). (PMID: 3015415).
Quintanilla, M.; Brown, K.; Ramsden, M.; Balmain, A. "Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis.". Nature. 322(6074): 78-80. (1986). (PMID: 3014349).
Balmain, A.; Quintanilla, M.; Brown, K.; Ramsden, M. "An approach to the molecular mechanisms of cancer induction.". J. Pathol.. 149(1): 3-8. (1986). (PMID: 3088239).
Kerr, I.B.; Lee, F.D.; Quintanilla, M.; Balmain, A. "Immunocytochemical demonstration of p21 ras family oncogene product in normal mucosa and in premalignant and malignant tumours of the colorectum.". Br. J. Cancer. 52(5): 695-700. (1985). (PMID: 3904802).
Cruces, J.; Diaz, V.; Quintanilla, M.; Renart, J.; Sebastian, J. "Purification and subunit structure of RNA polymerase II from different stages of Artemia development.". Eur. J. Biochem.. 141(2): 279-282. (1984). (PMID: 6734599).
Quintanilla, M.; Renart, J. "Purification and characterization of a novel UpN-specific endoribonuclease VI from Artemia larvae.". J. Biol. Chem.. 257(21): 12594-12599. (1982). (PMID: 6813326).
Sillero, M.A.; Villalba, R.; Moreno, A.; Quintanilla, M.; Lobatón, C.D.; Sillero, A. "Dinucleosidetriphosphatase from rat liver. Purification and properties.". Eur. J. Biochem.. 76(2): 331-337. (1977). (PMID: 196848).