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PUBLICACIONES

 

 

spacerTrabajos Publicados por María Isabel Sánchez Pérez
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  1. Melones-Herrero, J.; Alcalá, S.; Ruiz-Cañas, L.; Benítez-Buelga, C.; Batres-Ramos, S.; Calés, C.; Lorenzo, O.; Perona, R.; Quiroga, A.G.; Sainz, B.; Sánchez-Pérez, I. "Platinum iodido drugs show potential anti-tumor activity, affecting cancer cell metabolism and inducing ROS and senescence in gastrointestinal cancer cells.". Commun Biol. 7(1): 353. (2024). (PMID: 38519773).
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  2. Herrero, J.M.; Fabra, D.; Matesanz, A.I.; Hernández, C.; Sánchez-Pérez, I.; Quiroga, A.G. "Dithiobiureas Palladium(II) complexes' studies: From their synthesis to their biological action.". J Inorg Biochem. 246(): 112261. (2023). (PMID: 37271620).
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  3. Bargiela-Iparraguirre, J.; Herrero, J.M.; Pajuelo-Lozano, N.; Perez, M.; Perona, R.; Quiroga, A.G.; Calés, C.; Sanchez-Perez, I. "Regulatory effects of miR-19a on MAD2 expression and tumorigenesis in gastric cancer.". Genes Dis. 10(4): 1180-1182. (2023). (PMID: 37397556).
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  4. Ortega-Muelas, M.; Roche, O.; Fernández-Aroca, D.M.; Encinar, J.A.; Albandea-Rodríguez, D.; Arconada-Luque, E.; Pascual-Serra, R.; Muñoz, I.; Sánchez-Pérez, I.; Belandia, B.; Ruiz-Hidalgo, M.J.; Sánchez-Prieto, R. "ERK5 signalling pathway is a novel target of sorafenib: Implication in EGF biology.". J Cell Mol Med. (): . (2021). (PMID: 34655447).
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  5. Murillo-Cuesta, S.; Celaya, A.M.; Cervantes, B.; Bermúdez-Muñoz, J.M.; Rodríguez-de la Rosa, L.; Contreras, J.; Sánchez-Pérez, I.; Varela-Nieto, I. "Therapeutic efficiency of the APAF-1 antagonist LPT99 in a rat model of cisplatin-induced hearing loss.". Clin Transl Med. 11(4): e363. (2021). (PMID: 33931965).
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  6. Pajuelo-Lozano, N.; Alcalá, S.; Sainz, B.; Perona, R.; Sanchez-Perez, I. "Targeting MAD2 modulates stemness and tumorigenesis in human Gastric Cancer cell lines.". Theranostics. 10(21): 9601-9618. (2020). (PMID: 32863948).
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  7. Quiroga, A.G.; Cama, M.; Pajuelo-Lozano, N.; Álvarez-Valdés, A.; Perez, I.S. "New Findings in the Signaling Pathways of cis and trans Platinum Iodido Complexes' Interaction with DNA of Cancer Cells.". ACS Omega. 4(26): 21855-21861. (2019). (PMID: 31891063).
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  8. Fernández-Aroca, D.M.; Roche, O.; Sabater, S.; Pascual-Serra, R.; Ortega-Muelas, M.; Sánchez Pérez, I.; Belandia, B.; Ruiz-Hidalgo, M.J.; Sánchez-Prieto, R. "P53 pathway is a major determinant in the radiosensitizing effect of Palbociclib: Implication in cancer therapy.". Cancer Lett.. 451(): 23-33. (2019). (PMID: 30872077).
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  9. Celaya, A.M.; Sánchez-Pérez, I.; Bermúdez-Muñoz, J.M.; Rodríguez-de la Rosa, L.; Pintado-Berninches, L.; Perona, R.; Murillo-Cuesta, S.; Varela-Nieto, I. "Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss.". Elife. 8(): . (2019). (PMID: 30938680).
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  10. Pajuelo-Lozano, N.; Bargiela-Iparraguirre, J.; Dominguez, G.; Quiroga, A.G.; Perona, R.; Sanchez-Perez, I. "XPA, XPC, and XPD Modulate Sensitivity in Gastric Cisplatin Resistance Cancer Cells.". Front Pharmacol. 9(): 1197. (2018). (PMID: 30386247).
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  11. Niell, N.; Larriba, M.J.; Ferrer-Mayorga, G.; Sánchez-Pérez, I.; Cantero, R.; Real, F.X.; Del Peso, L.; Muñoz, A.; González-Sancho, J.M. "The human PKP2/plakophilin-2 gene is induced by Wnt/β-catenin in normal and colon cancer-associated fibroblasts.". Int. J. Cancer. 142(4): 792-804. (2018). (PMID: 29044515).
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  12. Echeverri, M.; Alvarez-Valdés, A.; Navas, F.; Perles, J.; Sánchez-Pérez, I.; Quiroga, A.G. "Using phosphine ligands with a biological role to modulate reactivity in novel platinum complexes.". R Soc Open Sci. 5(2): 171340. (2018). (PMID: 29515851).
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  13. Long, Y.; Stahl, Y.; Weidtkamp-Peters, S.; Postma, M.; Zhou, W.; Goedhart, J.; Sánchez-Pérez, M.I.; Gadella, T.W.J.; Simon, R.; Scheres, B.; Blilou, I. "In vivo FRET-FLIM reveals cell-type-specific protein interactions in Arabidopsis roots.". Nature. (): . (2017). (PMID: 28746306).
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  14. Bargiela-Iparraguirre, J.; Prado-Marchal, L.; Fernandez-Fuente, M.; Gutierrez-González, A.; Moreno-Rubio, J.; Muñoz-Fernandez, M.; Sereno, M.; Sanchez-Prieto, R.; Perona, R.; Sanchez-Perez, I. "CHK1 expression in Gastric Cancer is modulated by p53 and RB1/E2F1: implications in chemo/radiotherapy response.". Sci Rep. 6(): 21519. (2016). (PMID: 26867682).
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  15. Madejón, A.; Sheldon, J.; Francisco-Recuero, I.; Perales, C.; Domínguez-Beato, M.; Lasa, M.; Sánchez-Perez, I.; Muntané, J.; Domingo, E.; García-Samaniego, J.; Sánchez-Pacheco, A. "Hepatitis C virus-mediated Aurora B kinase inhibition modulates inflammatory pathway and viral infectivity.". J. Hepatol.. 63(2): 312-319. (2015). (PMID: 25733156).
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  16. Bargiela-Iparraguirre, J.; Prado-Marchal, L.; Pajuelo-Lozano, N.; Jiménez, B.; Perona, R.; Sánchez-Pérez, I. "Mad2 and BubR1 modulates tumourigenesis and paclitaxel response in MKN45 gastric cancer cells.". Cell Cycle. 13(22): 3590-3601. (2014). (PMID: 25483095).
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  17. Valero, M.L.; Cimas, F.J.; Arias, L.; Melgar-Rojas, P.; García, E.; Callejas-Valera, J.L.; García-Cano, J.; Serrano-Oviedo, L.; de la Cruz-Morcillo, M.Á.; Sánchez-Pérez, I.; Sánchez-Prieto, R. "E1a promotes c-Myc-dependent replicative stress: implications in glioblastoma radiosensitization.". Cell Cycle. 13(1): 52-61. (2014). (PMID: 24196438).
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  18. Gutiérrez-González, A.; Belda-Iniesta, C.; Bargiela-Iparraguirre, J.; Dominguez, G.; García Alfonso, P.; Perona, R.; Sanchez-Perez, I. "Targeting Chk2 improves gastric cancer chemotherapy by impairing DNA damage repair.". Apoptosis. 18(3): 347-360. (2013). (PMID: 23271172).
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  19. Alvarez-Castelao, B.; Muñoz, C.; Sánchez, I.; Goethals, M.; Vandekerckhove, J.; Castaño, J.G. "Reduced protein stability of human DJ-1/PARK7 L166P, linked to autosomal recessive Parkinson disease, is due to direct endoproteolytic cleavage by the proteasome.". Biochim. Biophys. Acta. 1823(2): 524-533. (2012). (PMID: 22173095).
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  20. Moncho-Amor, V.; Ibañez de Cáceres, I.; Bandres, E.; Martínez-Poveda, B.; Orgaz, J.L.; Sánchez-Pérez, I.; Zazo, S.; Rovira, A.; Albanell, J.; Jiménez, B.; Rojo, F.; Belda-Iniesta, C.; García-Foncillas, J.; Perona, R. "DUSP1/MKP1 promotes angiogenesis, invasion and metastasis in non-small-cell lung cancer.". Oncogene. 30(6): 668-678. (2011). (PMID: 20890299).
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  21. Peralta-Sastre, A.; Manguan-Garcia, C.; de Luis, A.; Belda-Iniesta, C.; Moreno, S.; Perona, R.; Sanchez-Perez, I. "Checkpoint kinase 1 modulates sensitivity to cisplatin after spindle checkpoint activation in SW620 cells.". Int. J. Biochem. Cell Biol.. 42(2): 318-328. (2010). (PMID: 19931410).
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  22. Cortes-Sempere, M.; Chattopadhyay, S.; Rovira, A.; Rodriguez-Fanjul, V.; Belda-Iniesta, C.; Tapia, M.; Cejas, P.; Machado-Pinilla, R.; Manguan-García, C.; Sánchez-Pérez, I.; Nistal, M.; Moratilla, C.; de Castro-Carpeño, J.; Gonzalez-Barón, M.; Albanell, J.; Perona, R. "MKP1 repression is required for the chemosensitizing effects of NF-kappaB and PI3K inhibitors to cisplatin in non-small cell lung cancer.". Cancer Lett.. 286(2): 206-216. (2009). (PMID: 19553005).
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  23. Sánchez-Pérez, I.; García Alonso, P.; Belda Iniesta, C. "Clinical impact of aneuploidy on gastric cancer patients.". Clin Transl Oncol. 11(8): 493-498. (2009). (PMID: 19661021).
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  24. Sanchez-Perez, I.; Manguan-Garcia, C.; Menacho-Marquez, M.; Murguía, J.R.; Perona, R. "hCCR4/cNOT6 targets DNA-damage response proteins.". Cancer Lett.. 273(2): 281-291. (2009). (PMID: 18818012).
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  25. Perona, R.; Moncho-Amor, V.; Machado-Pinilla, R.; Belda-Iniesta, C.; Sánchez Pérez, I. "Role of CHK2 in cancer development.". Clin Transl Oncol. 10(9): 538-542. (2008). (PMID: 18796370).
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  26. Machado-Pinilla, R.; Sánchez-Pérez, I.; Murguía, J.R.; Sastre, L.; Perona, R. "A dyskerin motif reactivates telomerase activity in X-linked dyskeratosis congenita and in telomerase-deficient human cells.". Blood. 111(5): 2606-2614. (2008). (PMID: 18057229).
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  27. Cortés Sempere, M.; Rodríguez Fanjul, V.; Sánchez Pérez, I.; Perona, R. "The role of the NFkappaB signalling pathway in cancer.". Clin Transl Oncol. 10(3): 143-147. (2008). (PMID: 18321816).
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  28. Belda-Iniesta, C.; Perona, R.; Carpeño, J.d.e. .C.; Cejas, P.; Casado, E.; Manguan-García, C.; Ibanez de Caceres, I.; Sanchez-Perez, I.; Andreu, F.B.; Ferreira, J.A.; Aguilera, A.; de la Peña, J.; Perez-Sánchez, E.; Madero, R.; Feliu, J.; Sereno, M.; González-Barón, M. "Human recombinant erythropoietin does not promote cancer growth in presence of functional receptors expressed in cancer cells.". Cancer Biol. Ther.. 6(10): 1600-1605. (2007). (PMID: 17938574).
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  29. Perona, R.; Sánchez-Pérez, I. "Signalling pathways involved in clinical responses to chemotherapy.". Clin Transl Oncol. 9(10): 625-633. (2007). (PMID: 17974523).
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  30. Sánchez-Pérez, I. "DNA repair inhibitors in cancer treatment.". Clin Transl Oncol. 8(9): 642-646. (2006). (PMID: 17005466).
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  31. Sanchez-Perez, I.; Renwick, S.J.; Crawley, K.; Karig, I.; Buck, V.; Meadows, J.C.; Franco-Sanchez, A.; Fleig, U.; Toda, T.; Millar, J.B. "The DASH complex and Klp5/Klp6 kinesin coordinate bipolar chromosome attachment in fission yeast.". EMBO J.. 24(16): 2931-2943. (2005). (PMID: 16079915).
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  32. Ajenjo, N.; Cañón, E.; Sánchez-Pérez, I.; Matallanas, D.; León, J.; Perona, R.; Crespo, P. "Subcellular localization determines the protective effects of activated ERK2 against distinct apoptogenic stimuli in myeloid leukemia cells.". J. Biol. Chem.. 279(31): 32813-32823. (2004). (PMID: 15173174).
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  33. Sanchez-Perez, I.; Rodriguez-Hernandez, C.J.; Manguan-García, C.; Torres, A.; Perona, R.; Murguía, J.R. "FK506 sensitizes mammalian cells to high osmolarity by modulating p38 MAP kinase activation.". Cell. Mol. Life Sci.. 61(6): 700-708. (2004). (PMID: 15052412).
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  34. Perona, R.; Sánchez-Pérez, I. "Control of oncogenesis and cancer therapy resistance.". Br. J. Cancer. 90(3): 573-577. (2004). (PMID: 14760366).
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  35. Domínguez, J.E.; Muñoz, M.C.; Zafra, D.; Sanchez-Perez, I.; Baqué, S.; Caron, M.; Mercurio, C.; Barberà, A.; Perona, R.; Gomis, R.; Guinovart, J.J. "The antidiabetic agent sodium tungstate activates glycogen synthesis through an insulin receptor-independent pathway.". J. Biol. Chem.. 278(44): 42785-42794. (2003). (PMID: 12925525).
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  36. Rodriguez-Hernandez, C.J.; Sanchez-Perez, I.; Gil-Mascarell, R.; Rodríguez-Afonso, A.; Torres, A.; Perona, R.; Murguia, J.R. "The immunosuppressant FK506 uncovers a positive regulatory cross-talk between the Hog1p and Gcn2p pathways.". J. Biol. Chem.. 278(36): 33887-33895. (2003). (PMID: 12813040).
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  37. Decottignies, A.; Sanchez-Perez, I.; Nurse, P. "Schizosaccharomyces pombe essential genes: a pilot study.". Genome Res.. 13(3): 399-406. (2003). (PMID: 12618370).
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  38. Madrid, O.; Varea, S.; Sanchez-Perez, I.; Gomez-Garcia, L.; De Miguel, E.; Gomez De Segura, I.A.; Perona, R. "Growth hormone protects against radiotherapy-induced cell death.". Eur. J. Endocrinol.. 147(4): 535-541. (2002). (PMID: 12370117).
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  39. Sánchez-Pérez, I.; Benitah, S.A.; Martínez-Gomariz, M.; Lacal, J.C.; Perona, R. "Cell stress and MEKK1-mediated c-Jun activation modulate NFkappaB activity and cell viability.". Mol. Biol. Cell. 13(8): 2933-2945. (2002). (PMID: 12181357).
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  40. Sánchez-Pérez, I.; Martínez-Gomariz, M.; Williams, D.; Keyse, S.M.; Perona, R. "CL100/MKP-1 modulates JNK activation and apoptosis in response to cisplatin.". Oncogene. 19(45): 5142-5152. (2000). (PMID: 11064451).
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  41. Sánchez-Pérez, I.; Perona, R. "Lack of c-Jun activity increases survival to cisplatin.". FEBS Lett.. 453(1-2): 151-158. (1999). (PMID: 10403393).
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  42. Sánchez-Perez, I.; Murguía, J.R.; Perona, R. "Cisplatin induces a persistent activation of JNK that is related to cell death.". Oncogene. 16(4): 533-540. (1998). (PMID: 9484843).
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  43. Perona, R.; Montaner, S.; Saniger, L.; Sánchez-Pérez, I.; Bravo, R.; Lacal, J.C. "Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins.". Genes Dev.. 11(4): 463-475. (1997). (PMID: 9042860).
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Instituto de Investigaciones Biomédicas "Alberto Sols"
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