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PUBLICACIONES

 

 

spacerTrabajos Publicados por Beatriz Alvarez Castelao
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  1. Sánchez-Lanzas, R.; Alvarez-Castelao, B.; Bermejo, T.; Ayuso, T.; Tuñón, T.; Castaño, J.G. "Protein degradation in a LAMP-2-deficient B-lymphoblastoid cell line from a patient with Danon disease.". Biochim. Biophys. Acta. 1862(8): 1423-1432. (2016). (PMID: 27130438).
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  2. Alvarez-Castelao, B.; Gorostidi, A.; Ruíz-Martínez, J.; López de Munain, A.; Castaño, J.G. "Epitope Mapping of Antibodies to Alpha-Synuclein in LRRK2 Mutation Carriers, Idiopathic Parkinson Disease Patients, and Healthy Controls.". Front Aging Neurosci. 6(): 169. (2014). (PMID: 25076905).
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  3. Alvarez-Castelao, B.; Goethals, M.; Vandekerckhove, J.; Castaño, J.G. "Mechanism of cleavage of alpha-synuclein by the 20S proteasome and modulation of its degradation by the RedOx state of the N-terminal methionines.". Biochim. Biophys. Acta. 1843(2): 352-365. (2014). (PMID: 24315858).
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  4. Alvarez-Castelao, B.; Losada, F.; Ahicart, P.; Castaño, J.G. "The N-terminal region of Nurr1 (a.a 1-31) is essential for its efficient degradation by the ubiquitin proteasome pathway.". PLoS ONE. 8(2): e55999. (2013). (PMID: 23409108).
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  5. Alvarez-Castelao, B.; Ruiz-Rivas, C.; Castaño, J.G. "A critical appraisal of quantitative studies of protein degradation in the framework of cellular proteostasis.". Biochem Res Int. 2012(): 823597. (2012). (PMID: 23119163).
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  6. Alvarez-Castelao, B.; Muñoz, C.; Sánchez, I.; Goethals, M.; Vandekerckhove, J.; Castaño, J.G. "Reduced protein stability of human DJ-1/PARK7 L166P, linked to autosomal recessive Parkinson disease, is due to direct endoproteolytic cleavage by the proteasome.". Biochim. Biophys. Acta. 1823(2): 524-533. (2012). (PMID: 22173095).
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  7. Alvarez-Castelao, B.; Castaño, J.G. "Synphilin-1 inhibits alpha-synuclein degradation by the proteasome.". Cell. Mol. Life Sci.. 68(15): 2643-2654. (2011). (PMID: 21103907).
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  8. Alvarez-Castelao, B.; Martín-Guerrero, I.; García-Orad, A.; Castaño, J.G. "Cytomegalovirus promoter up-regulation is the major cause of increased protein levels of unstable reporter proteins after treatment of living cells with proteasome inhibitors.". J. Biol. Chem.. 284(41): 28253-28262. (2009). (PMID: 19679666).
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  9. Kong, X.; Alvarez-Castelao, B.; Lin, Z.; Castaño, J.G.; Caro, J. "Constitutive/hypoxic degradation of HIF-alpha proteins by the proteasome is independent of von Hippel Lindau protein ubiquitylation and the transactivation activity of the protein.". J. Biol. Chem.. 282(21): 15498-15505. (2007). (PMID: 17403672).
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  10. Díaz-Hernández, M.; Valera, A.G.; Morán, M.A.; Gómez-Ramos, P.; Alvarez-Castelao, B.; Castaño, J.G.; Hernández, F.; Lucas, J.J. "Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain.". J. Neurochem.. 98(5): 1585-1596. (2006). (PMID: 16787406).
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  11. Alvarez-Castelao, B.; Castaño, J.G. "Mechanism of direct degradation of IkappaBalpha by 20S proteasome.". FEBS Lett.. 579(21): 4797-4802. (2005). (PMID: 16098527).
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  12. Martìn-Clemente, B.; Alvarez-Castelao, B.; Mayo, I.; Sierra, A.B.; Dìaz, V.; Milán, M.; Fariñas, I.; Gómez-Isla, T.; Ferrer, I.; Castaño, J.G. "alpha-Synuclein expression levels do not significantly affect proteasome function and expression in mice and stably transfected PC12 cell lines.". J. Biol. Chem.. 279(51): 52984-52990. (2004). (PMID: 15466467).
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