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PUBLICACIONES

 

 

spacerTrabajos Publicados por Leandro Sastre Garzón
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  1. Machado-Pinilla, R.; Carrillo, J.; Manguan-Garcia, C.; Sastre, L.; Mentzer, A.; Gu, B.W.; Mason, P.J.; Perona, R. "Defects in mTR stability and telomerase activity produced by the Dkc1 A353V mutation in dyskeratosis congenita are rescued by a peptide from the dyskerin TruB domain.". Clin Transl Oncol. 14(10): 755-763. (2012). (PMID: 22855157).
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  2. Carrillo, J.; Martínez, P.; Solera, J.; Moratilla, C.; González, A.; Manguán-García, C.; Aymerich, M.; Canal, L.; Del Campo, M.; Dapena, J.L.; Escoda, L.; García-Sagredo, J.M.; Martín-Sala, S.; Rives, S.; Sevilla, J.; Sastre, L.; Perona, R. "High resolution melting analysis for the identification of novel mutations in DKC1 and TERT genes in patients with dyskeratosis congenita.". Blood Cells Mol. Dis.. 49(3-4): 140-146. (2012). (PMID: 22664374).
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  3. Sastre, L. "New DNA sequencing technologies open a promising era for cancer research and treatment.". Clin Transl Oncol. 13(5): 301-306. (2011). (PMID: 21596657).
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  4. Moncho-Amor, V.; Galardi-Castilla, M.; Perona, R.; Sastre, L. "The dual-specificity protein phosphatase MkpB, homologous to mammalian MKP phosphatases, is required for D. discoideum post-aggregative development and cisplatin response.". Differentiation. 81(3): 199-207. (2011). (PMID: 21300429).
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  5. Galardi-Castilla, M.; Garciandía, A.; Suarez, T.; Sastre, L. "The Dictyostelium discoideum acaA gene is transcribed from alternative promoters during aggregation and multicellular development.". PLoS ONE. 5(10): . (2010). (PMID: 20949015).
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  6. Vicente, J.J.; Galardi-Castilla, M.; Escalante, R.; Sastre, L. "Structural and functional studies of a family of Dictyostelium discoideum developmentally regulated, prestalk genes coding for small proteins.". BMC Microbiol.. 8(): 1. (2008). (PMID: 18173832).
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  7. Galardi-Castilla, M.; Pergolizzi, B.; Bloomfield, G.; Skelton, J.; Ivens, A.; Kay, R.R.; Bozzaro, S.; Sastre, L. "SrfB, a member of the Serum Response Factor family of transcription factors, regulates starvation response and early development in Dictyostelium.". Dev. Biol.. 316(2): 260-274. (2008). (PMID: 18339368).
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  8. Machado-Pinilla, R.; Sánchez-Pérez, I.; Murguía, J.R.; Sastre, L.; Perona, R. "A dyskerin motif reactivates telomerase activity in X-linked dyskeratosis congenita and in telomerase-deficient human cells.". Blood. 111(5): 2606-2614. (2008). (PMID: 18057229).
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  9. Metcalf, T.; van der Wel, H.; Escalante, R.; Sastre, L.; West, C.M. "Role of SP65 in assembly of the Dictyostelium discoideum spore coat.". Eukaryotic Cell. 6(7): 1137-1149. (2007). (PMID: 17416892).
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  10. Romeralo, M.; Escalante, R.; Sastre, L.; Lado, C. "Molecular systematics of dictyostelids: 5.8S ribosomal DNA and internal transcribed spacer region analyses.". Eukaryotic Cell. 6(1): 110-116. (2007). (PMID: 17056743).
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  11. Escalante, R.; Sastre, L. "Investigating gene expression: in situ hybridization and reporter genes.". Methods Mol. Biol.. 346(): 247-260. (2006). (PMID: 16957295).
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  12. Torija, P.; Vicente, J.J.; Rodrigues, T.B.; Robles, A.; Cerdán, S.; Sastre, L.; Calvo, R.M.; Escalante, R. "Functional genomics in Dictyostelium: MidA, a new conserved protein, is required for mitochondrial function and development.". J. Cell. Sci.. 119(Pt 6): 1154-1164. (2006). (PMID: 16507593).
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  13. Escalante, R.; Iranfar, N.; Sastre, L.; Loomis, W.F. "Identification of genes dependent on the MADS box transcription factor SrfA in Dictyostelium discoideum development.". Eukaryotic Cell. 3(2): 564-566. (2004). (PMID: 15075287).
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  14. Alonso, A.; Morales, G.; Escalante, R.; Campanario, E.; Sastre, L.; Martinez, J.L. "Overexpression of the multidrug efflux pump SmeDEF impairs Stenotrophomonas maltophilia physiology.". J. Antimicrob. Chemother.. 53(3): 432-434. (2004). (PMID: 14739147).
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  15. Escalante, R.; Yamada, Y.; Cotter, D.; Sastre, L.; Sameshima, M. "The MADS-box transcription factor SrfA is required for actin cytoskeleton organization and spore coat stability during Dictyostelium sporulation.". Mech. Dev.. 121(1): 51-56. (2004). (PMID: 14706699).
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  16. Escalante, R.; Moreno, N.; Sastre, L. "Dictyostelium discoideum developmentally regulated genes whose expression is dependent on MADS box transcription factor SrfA.". Eukaryotic Cell. 2(6): 1327-1335. (2003). (PMID: 14665466).
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  17. Martinez-Lamparero, A.; Casero, M.C.; Ortiz-Caro, J.; Sastre, L. "Regulation of promoter occupancy during activation of cryptobiotic embryos from the crustacean Artemia franciscana.". J. Exp. Biol.. 206(Pt 9): 1565-1573. (2003). (PMID: 12654895).
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  18. Escalante, R.; Sastre, L. "Regulated expression of the MADS-box transcription factor SrfA mediates activation of gene expression by protein kinase A during Dictyostelium sporulation.". Mech. Dev.. 117(1-2): 201-208. (2002). (PMID: 12204259).
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  19. Avila, S.; Casero, M.C.; Fernandez-Cantón, R.; Sastre, L. "Transactivation domains are not functionally conserved between vertebrate and invertebrate serum response factors.". Eur. J. Biochem.. 269(15): 3669-3677. (2002). (PMID: 12153563).
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  20. Escalante, R.; Sastre, L. "cAMP and DIF-1 repress the expression of the Dictyostelium MADS-box gene srfA at early stages of development.". Biochem. Biophys. Res. Commun.. 285(3): 820-824. (2001). (PMID: 11453666).
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  21. Escalante, R.; Vicente, J.J.; Moreno, N.; Sastre, L. "The MADS-box gene srfA is expressed in a complex pattern under the control of alternative promoters and is essential for different aspects of Dictyostelium development.". Dev. Biol.. 235(2): 314-329. (2001). (PMID: 11437439).
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  22. Casero, M.C.; Sastre, L. "Characterization of a functional serum response element in the Actin403 gene promoter from the crustacean Artemia franciscana.". Eur. J. Biochem.. 268(9): 2587-2592. (2001). (PMID: 11322877).
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  23. Casero, M.C.; Sastre, L. "A serum response factor homologue is expressed in ectodermal tissues during development of the crustacean Artemia franciscana.". Mech. Dev.. 96(2): 229-232. (2000). (PMID: 10960789).
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  24. Sáez, A.G.; Escalante, R.; Sastre, L. "High DNA sequence variability at the alpha 1 Na/K-ATPase locus of Artemia franciscana (brine shrimp): polymorphism in a gene for salt-resistance in a salt-resistant organism.". Mol. Biol. Evol.. 17(2): 235-250. (2000). (PMID: 10677846).
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  25. Sastre, L. "Isolation and characterization of the gene coding for Artemia franciscana TATA-binding protein: expression in cryptobiotic and developing embryos.". Biochim. Biophys. Acta. 1445(3): 271-282. (1999). (PMID: 10366711).
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  26. Escalante, R.; Sastre, L. "A Serum Response Factor homolog is required for spore differentiation in Dictyostelium.". Development. 125(19): 3801-3808. (1998). (PMID: 9729488).
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  27. García-Sáez, A.; Perona, R.; Sastre, L. "Polymorphism and structure of the gene coding for the alpha 1 subunit of the Artemia franciscana Na/K-ATPase.". Biochem. J.. 321 ( Pt 2)(): 509-518. (1997). (PMID: 9020888).
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  28. Martinez-Lamparero, A.; Casero, M.C.; Ortiz-Caro, J.; Sastre, L. "Transcriptional regulation during the activation and development of Artemia franciscana encysted embryos.". Int. J. Dev. Biol.. Suppl 1(): . (1996). (PMID: 9087711).
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  29. Ortega, M.A.; Díaz-Guerra, M.; Sastre, L. "Actin gene structure in two Artemia species, A. franciscana and A. parthenogenetica.". J. Mol. Evol.. 43(3): 224-235. (1996). (PMID: 8703088).
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  30. Escalante, R.; Sastre, L. "Tissue-specific expression of two Artemia franciscana sarco/endoplasmic reticulum Ca-ATPase isoforms.". J. Histochem. Cytochem.. 44(4): 321-325. (1996). (PMID: 8601691).
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  31. Escalante, R.; Sastre, L. "Tissue-specific alternative promoters regulate the expression of the two sarco/endoplasmic reticulum Ca-ATPase isoforms from Artemia franciscana.". DNA Cell Biol.. 14(10): 893-900. (1995). (PMID: 7546295).
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  32. Escalante, R.; García-Sáez, A.; Sastre, L. "In situ hybridization analyses of Na, K-ATPase alpha-subunit expression during early larval development of Artemia franciscana.". J. Histochem. Cytochem.. 43(4): 391-399. (1995). (PMID: 7897181).
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  33. Escalante, R.; Sastre, L. "Identification of an Artemia franciscana retropseudogene containing part of the last exons of the sarco/endoplasmic reticulum Ca-ATPase-encoding SERCA gene.". Gene. 149(2): 377-378. (1994). (PMID: 7959022).
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  34. Escalante, R.; Sastre, L. "Structure of Artemia franciscana sarco/endoplasmic reticulum Ca-ATPase gene.". J. Biol. Chem.. 269(17): 13005-13012. (1994). (PMID: 8175720).
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  35. Escalante, R.; García-Sáez, A.; Ortega, M.A.; Sastre, L. "Gene expression after resumption of development of Artemia franciscana cryptobiotic embryos.". Biochem. Cell Biol.. 72(3-4): 78-83. (1994). (PMID: 7818853).
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  36. Escalante, R.; Sastre, L. "Similar alternative splicing events generate two sarcoplasmic or endoplasmic reticulum Ca-ATPase isoforms in the crustacean Artemia franciscana and in vertebrates.". J. Biol. Chem.. 268(19): 14090-14095. (1993). (PMID: 8314776).
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  37. Macías, M.T.; Palmero, I.; Sastre, L. "Cloning of a cDNA encoding an Artemia franciscana Na/K ATPase alpha-subunit.". Gene. 105(2): 197-204. (1991). (PMID: 1657719).
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  38. Macias, M.T.; Sastre, L. "Molecular cloning and expression of four actin isoforms during Artemia development.". Nucleic Acids Res.. 18(17): 5219-5225. (1990). (PMID: 2402445).
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  39. Palmero, I.; Sastre, L. "Complementary DNA cloning of a protein highly homologous to mammalian sarcoplasmic reticulum Ca-ATPase from the crustacean Artemia.". J. Mol. Biol.. 210(4): 737-748. (1989). (PMID: 2533270).
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  40. Díaz-Guerra, M.; Quintanilla, M.; Palmero, I.; Sastre, L.; Renart, J. "Differential expression of a gene highly homologous to c-ras during the development of the brine shrimp Artemia.". Biochem. Biophys. Res. Commun.. 162(2): 802-808. (1989). (PMID: 2502981).
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  41. Palmero, I.; Renart, J.; Sastre, L. "Isolation of cDNA clones coding for mitochondrial 16S ribosomal RNA from the crustacean Artemia.". Gene. 68(2): 239-248. (1988). (PMID: 3220256).
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  42. Sastre, L.; Roman, J.M.; Teplow, D.B.; Dreyer, W.J.; Gee, C.E.; Larson, R.S.; Roberts, T.M.; Springer, T.A. "A partial genomic DNA clone for the alpha subunit of the mouse complement receptor type 3 and cellular adhesion molecule Mac-1.". Proc. Natl. Acad. Sci. U.S.A.. 83(15): 5644-5648. (1986). (PMID: 2942940).
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  43. Sastre, L.; Kishimoto, T.K.; Gee, C.; Roberts, T.; Springer, T.A. "The mouse leukocyte adhesion proteins Mac-1 and LFA-1: studies on mRNA translation and protein glycosylation with emphasis on Mac-1.". J. Immunol.. 137(3): 1060-1065. (1986). (PMID: 3522736).
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  44. Gee, C.E.; Griffin, J.; Sastre, L.; Miller, L.J.; Springer, T.A.; Piwnica-Worms, H.; Roberts, T.M. "Differentiation of myeloid cells is accompanied by increased levels of pp60c-src protein and kinase activity.". Proc. Natl. Acad. Sci. U.S.A.. 83(14): 5131-5135. (1986). (PMID: 2425362).
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  45. Renart, M.F.; Sastre, L.; Díaz, V.; Sebastián, J. "Purification and subunit structure of RNA polymerases I and II from Dictyostelium discoideum vegetative cells.". Mol. Cell. Biochem.. 66(1): 21-29. (1985). (PMID: 3982401).
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  46. Sastre, L.; Sebastián, J. "Developmental changes in poly(A) polymerase activity in Artemia.". Eur. J. Biochem.. 135(1): 69-74. (1983). (PMID: 6309518).
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  47. Sastre, L.; Sebastián, J. "In vitro polyadenylation of messenger ribonucleoprotein particles stored in Artemia dormant embryos.". Biochem. Biophys. Res. Commun.. 108(4): 1609-1613. (1982). (PMID: 6129848).
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