1 mar | 2026 Molecular profiling unveils genetic complexity and identifies potential new driver mechanisms in head and neck paragangliomas. Mellid, S, Caleiras, E, Martínez-Montes, ÁM, Arenas, A, Jiménez, S, Monteagudo, M, Letón, R, Radu, R, Álvarez-Díaz, R, Arroba, E, Diaz-Talavera, A, Martínez-Puente, N, Álvarez-Escolá, C, Pineda, M, Balbín, M, Al-Shahrour, F, Rodriguez-Antona, C , Montero-Conde, C , Leandro-García, LJ, Honrado, E, Soria-Tristán, M, Robledo, M, Cascón, A. Genes Dis - 13 (2) : 101705 (PMID: 41216501) (doi:10.1016/j.gendis.2025.101705)
10 feb | 2026 A single-step radiolabeling strategy for PET, SPECT, and therapeutic radionuclides using nanoparticles as a universal chelator. Herraiz, A, Rodríguez-San-Pedro, A, Casquero-Veiga, M, Cossío, U, Arias-Ramos, N , Gutiérrez, L, Romero-Sanz, E, Luján-Rodríguez, VM, Cerón, C, Oteo, M, González-Paredes, A, López-Larrubia, P , Rosales, RTM, Cortes-Canteli, M , Morcillo, MA, Ruiz-Cabello, J, Pellico, J, Herranz, F. Npj Imaging - 4 (1) : 8 (PMID: 41667650) (doi:10.1038/s44303-026-00142-1)
10 feb | 2026 Protective effect of melatonin against age-related ischemia-reperfusion injury is associated with the NLRP3 inflammasome pathway. Ben Jeddou, I, Berlana, Á , Rey, E, Ben Abdennebi, H, Almawi, WY, Omri, A, Valverde, ÁM , González-Rodriguez, Á , Zaouali, MA. J Physiol Biochem - 82 (1) : 9 (PMID: 41665836) (doi:10.1007/s13105-026-01145-7)
6 feb | 2026 A Plastic EMP1+ to LGR5+ Cell State Conversion as a Bypass to KRASG12D Pharmacologic Inhibition in Metastatic Colorectal Cancer. Centonze, A, Roura, AJ, Novillo-Font, M, Giordano, C, Hernando-Momblona, X, Llanses, M, Prats, P, Sevillano, M, Cabot, D, Novell, M, Pabst, G, Andersch, F, Cañellas-Socias, A, Zhang, C, Giakoumakis, NN, Sparks, H, Dunsby, C, Colombelli, J, Fernández-Barral, A , Sancho, E, Stephan-Otto Attolini, C, Muñoz, A , Barbachano, A , Palmer, HG , Martínez-Quintanilla, J, Zuber, J, Blaj, C, Quintana, E, Cortina, C, Marti-Renom, MA, Batlle, E. Cancer Discov - 16 (2) : 320-344 (PMID: 41128661) (doi:10.1158/2159-8290.CD-25-0679)
3 feb | 2026 Bioinformatic Analyses of the Ataxin-2 Family Since Algae Emphasize Its Small Isoforms, Large Chimerisms, and the Importance of Human Exon 1B as Target of Therapies to Prevent Neurodegeneration. Auburger, GWJ, Key, J, Gispert, S, Lastres-Becker, I , Almaguer-Mederos, LE, Bassa, C, Auburger, A, Auburger, G, Arsovic, A, Deller, T, Sen, NE. Int J Mol Sci - 27 (3) (PMID: 41683920) (doi:10.3390/ijms27031499)
28 ene | 2026 A type I interferon-mitochondrial axis regulates efferocytosis and interferon-stimulated gene induction in macrophages. Dunphy, G, Adán-Barrientos, I, Fernández-Delgado, I, Villarroya-Beltri, C, Heras-Murillo, I, Moya-Ruiz, E, Sánchez-Álvarez, M , Jarit-Cabanillas, A, Del Pozo, MA, Guerra, S, Sánchez-Madrid, F, Sancho, D. Immunity (PMID: 41610845) (doi:10.1016/j.immuni.2025.12.010)
23 ene | 2026 The inhibition of Il1β synthesis mediated by a novel pyridine-sulfonamide compound protects against the progression of metabolic dysfunction-associated steatotic liver disease. Berlana, Á , Rey, E, Fresno-Ventura, E, Gomez-Gutierrez, P, Vega, M, García-Monzón, C, González-Rodríguez, Á . Biomed Pharmacother - 195 : 119052 (PMID: 41579710) (doi:10.1016/j.biopha.2026.119052)
16 ene | 2026 PPARβ/δ contributes to the antidiabetic effect and the increase in GDF15 caused by metformin. Jurado-Aguilar, J, Barroso, E, Rada, P , Peyman, M, Rostami, A, Balsinde, J, Valverde, ÁM , Wahli, W, Palomer, X, Vázquez-Carrera, M. Acta Pharmacol Sin (PMID: 41545750) (doi:10.1038/s41401-025-01705-5)
13 ene | 2026 Modulation of the Receptor Tyrosine Kinase TIE2/Tek Pathway by NRF2 Activation in Neurovascular Endothelial Cells. Cazalla, E , García-Yagüe, ÁJ , Pajares, M , Jiménez-Villegas, J , Escoll, M , Rojo, AI , Cuadrado, A . Int J Mol Sci - 27 (2) (PMID: 41596422) (doi:10.3390/ijms27020770)
13 ene | 2026 NRF2 AT THE CROSSROADS OF PARKINSON'S DISEASE AND AGING: MECHANISTIC INSIGHTS AND TRANSLATIONAL PERSPECTIVES. Áj, GY , N, E, Dinkova-Kostova, AT, Ai, R , Pg, S, A, D, V, T, van Goor, H, Lastres-Becker, I . Free Radic Biol Med (PMID: 41539374) (doi:10.1016/j.freeradbiomed.2026.01.023)
7 ene | 2026 Enhancing TFEA.ChIP with ENCODE regulatory maps for generalizable transcription factor enrichment. Berrouayel, Y , Del Peso, L . Brief Bioinform - 27 (1) (PMID: 41527853) (doi:10.1093/bib/bbaf715)
6 ene | 2026 Uncovering the Role of Thrombospodin-1 and Occludin as Potential Prognostic and Diagnostic Biomarkers in Traumatic Brain Injury. Decouty-Pérez, C, Valencia, I, Alvarez-Rubal, M, Martínez-Cuevas, E, Farré-Alins, V, Calzada, MJ, Penalba, A, Montaner, J, Rodríguez de Cía, J, Taravilla-Loma, M, Hernández-García, BJ, Fuertes-Yebra, E, González-Rodríguez, Á , Lopez-Rodriguez, AB, Egea, J. Int J Mol Sci - 27 (2) (PMID: 41596222) (doi:10.3390/ijms27020571)
5 ene | 2026 De novo H3.3K27M-altered diffuse midline glioma in human brainstem organoids to dissect GD2 CAR T cell function. Bessler, N, Wezenaar, AKL, Ariese, HCR, Honhoff, C, Dommann, N, Wehrens, EJ, Ruiz Moreno, C, van den Broek, TJM, Collot, RVU, Kloosterman, DJ, Keramati, F, Roosen, M, de Blank, S, van Vliet, E, Barrera Román, M, Gatti, LCDE, Ertürk, A, Kuball, J, Sebestyén, Z, Kool, M, Patrizi, S, Miele, E, Künkele, A, Kranendonk, MEG, Cornel, AM, Nierkens, S, Mayer, C, Stunnenberg, HG, Alemany, A, Alieva, M , Rios, AC. Nat Cancer (PMID: 41492091) (doi:10.1038/s43018-025-01084-0)
5 ene | 2026 GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model. Silva-Llanes, I , Smith, LA , Abdelkader-Guillén, A , Jiménez-Villegas, J , Sarrió, D , Moreno-Bueno, G , Lastres-Becker, I . J Biomed Sci - 33 (1) : 6 (PMID: 41486173) (doi:10.1186/s12929-025-01210-1)
2 ene | 2026 Assessing Amplification Quality and Bias in MDA Methods Through Comparative Analysis of Short-Read Sequencing. Lozano-Escobar, ED , Mateo-Cáceres, V , Mayoral-Campos, C , Redrejo-Rodríguez, M . Methods Mol Biol - 3003 : 131-148 (PMID: 41478953) (doi:10.1007/978-1-0716-5060-8_10)