Calleja-Conde, J.; Echeverry-Alzate, V.; Sanz-SanCristobal, M. ; Alonso-Gil, S. ; Giné, E.; Bühler, K.; López-Moreno, J.A.; Perez-Castillo, A. ; Morales-Garcia, J.A. "Therapeutic properties of ayahuasca component N,N-Dimethyltryptamine in a pre-clinical model of Parkinson's disease." . Exp Neurol. (): 115822. (2026). (PMID: 42128256).
Sierra-Magro, A. ; Bartolome, F.; Lozano-Muñoz, D. ; Alarcón-Gil, J. ; Gine, E.; Sanz-SanCristobal, M. ; Alonso-Gil, S. ; Cortes-Canteli, M. ; Carro, E.; Pérez-Castillo, A. ; Morales-García, J.A. "C/EBPβ Regulates TFAM Expression, Mitochondrial Function and Autophagy in Cellular Models of Parkinson's Disease." . Int J Mol Sci. 24(2): . (2023). (PMID: 36674978).
Alarcon-Gil, J. ; Sierra-Magro, A. ; Morales-Garcia, J.A. ; Sanz-SanCristobal, M. ; Alonso-Gil, S. ; Cortes-Canteli, M. ; Niso-Santano, M.; Martínez-Chacón, G.; Fuentes, J.M.; Santos, A. ; Perez-Castillo, A. "Neuroprotective and Anti-Inflammatory Effects of Linoleic Acid in Models of Parkinson's Disease: The Implication of Lipid Droplets and Lipophagy." . Cells. 11(15): . (2022). (PMID: 35892594).
Morales-Garcia, J.A. ; Calleja-Conde, J.; Lopez-Moreno, J.A.; Alonso-Gil, S. ; Sanz-SanCristobal, M. ; Riba, J.; Perez-Castillo, A. "N,N-dimethyltryptamine compound found in the hallucinogenic tea ayahuasca, regulates adult neurogenesis in vitro and in vivo." . Transl Psychiatry. 10(1): 331. (2020). (PMID: 32989216).
Morales-Garcia, J.A. ; Alonso-Gil, S. ; Santos, Á.; Perez-Castillo, A. "Phosphodiesterase 7 Regulation in Cellular and Rodent Models of Parkinson's Disease." . Mol. Neurobiol.. (): . (2019). (PMID: 31473904).
Morales-Garcia, J.A. ; Gine, E.; Hernandez-Encinas, E.; Aguilar-Morante, D. ; Sierra-Magro, A. ; Sanz-SanCristobal, M. ; Alonso-Gil, S. ; Sanchez-Lanzas, R.; Castaño, J.G. ; Santos, A. ; Perez-Castillo, A. "CCAAT/Enhancer binding protein β silencing mitigates glial activation and neurodegeneration in a rat model of Parkinson's disease." . Sci Rep. 7(1): 13526. (2017). (PMID: 29051532).
Morales-García, J.A. ; de la Fuente Revenga, M.; Alonso-Gil, S. ; Rodríguez-Franco, M.I.; Feilding, A.; Perez-Castillo, A. ; Riba, J. "The alkaloids of Banisteriopsis caapi, the plant source of the Amazonian hallucinogen Ayahuasca, stimulate adult neurogenesis in vitro." . Sci Rep. 7(1): 5309. (2017). (PMID: 28706205).
Morales-Garcia, J.A. ; Echeverry-Alzate, V.; Alonso-Gil, S. ; Sanz-SanCristobal, M. ; Lopez-Moreno, J.A.; Gil, C.; Martinez, A.; Santos, A. ; Perez-Castillo, A. "Phosphodiesterase7 Inhibition Activates Adult Neurogenesis in Hippocampus and Subventricular Zone In Vitro and In Vivo." . Stem Cells. 35(2): 458-472. (2017). (PMID: 27538853).
de la Fuente Revenga, M.; Pérez, C. ; Morales-García, J.A. ; Alonso-Gil, S. ; Pérez-Castillo, A. ; Caignard, D.H.; Yáñez, M.; Gamo, A.M.; Rodríguez-Franco, M.I. "Neurogenic Potential Assessment and Pharmacological Characterization of 6-Methoxy-1,2,3,4-tetrahydro-β-carboline (Pinoline) and Melatonin-Pinoline Hybrids." . ACS Chem Neurosci. 6(5): 800-810. (2015). (PMID: 25815906).
de la Fuente Revenga, M.; Fernández-Sáez, N.; Herrera-Arozamena, C.; Morales-García, J.A. ; Alonso-Gil, S. ; Pérez-Castillo, A. ; Caignard, D.H.; Rivara, S.; Rodríguez-Franco, M.I. "Novel N-Acetyl Bioisosteres of Melatonin: Melatonergic Receptor Pharmacology, Physicochemical Studies, and Phenotypic Assessment of their Neurogenic Potential." . J. Med. Chem.. (): . (2015). (PMID: 26023814).
Morales-Garcia, J.A. ; Alonso-Gil, S. ; Gil, C.; Martinez, A.; Santos, A. ; Perez-Castillo, A. "Phosphodiesterase 7 Inhibition Induces Dopaminergic Neurogenesis in Hemiparkinsonian Rats." . Stem Cells Transl Med. (): . (2015). (PMID: 25925836).
Morales-Garcia, J.A. ; Aguilar-Morante, D. ; Hernandez-Encinas, E.; Alonso-Gil, S. ; Gil, C.; Martinez, A.; Santos, A. ; Perez-Castillo, A. "Silencing phosphodiesterase 7B gene by lentiviral-shRNA interference attenuates neurodegeneration and motor deficits in hemiparkinsonian mice." . Neurobiol. Aging. 36(2): 1160-1173. (2015). (PMID: 25457552).
García, A.M.; Brea, J.; Morales-García, J.A. ; Perez, D.I.; González, A.; Alonso-Gil, S. ; Gracia-Rubio, I.; Ros-Simó, C.; Conde, S.; Cadavid, M.I.; Loza, M.I.; Perez-Castillo, A. ; Valverde, O.; Martinez, A.; Gil, C. "Modulation of cAMP-specific PDE without emetogenic activity: new sulfide-like PDE7 inhibitors." . J. Med. Chem.. 57(20): 8590-8607. (2014). (PMID: 25264825).
López-Iglesias, B.; Pérez, C. ; Morales-García, J.A. ; Alonso-Gil, S. ; Pérez-Castillo, A. ; Romero, A.; López, M.G.; Villarroya, M.; Conde, S.; Rodríguez-Franco, M.I. "New melatonin-N,N-dibenzyl(N-methyl)amine hybrids: potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for Alzheimer's disease." . J. Med. Chem.. 57(9): 3773-3785. (2014). (PMID: 24738476).
Morales-Garcia, J.A. ; Palomo, V.; Redondo, M.; Alonso-Gil, S. ; Gil, C.; Martinez, A.; Perez-Castillo, A. "Crosstalk between phosphodiesterase 7 and glycogen synthase kinase-3: two relevant therapeutic targets for neurological disorders." . ACS Chem Neurosci. 5(3): 194-204. (2014). (PMID: 24437940).
Chavarría, C.; Perez, D.I.; Pérez, C. ; Morales Garcia, J.A. ; Alonso-Gil, S. ; Pérez-Castillo, A. ; Gil, C.; Souza, J.M.; Porcal, W. "Microwave-assisted synthesis of hydroxyphenyl nitrones with protective action against oxidative stress." . Eur J Med Chem. 58(): 44-49. (2012). (PMID: 23085773).
Morales-Garcia, J.A. ; Luna-Medina, R. ; Alonso-Gil, S. ; Sanz-Sancristobal, M. ; Palomo, V.; Gil, C.; Santos, A. ; Martinez, A.; Perez-Castillo, A. "Glycogen synthase kinase 3 inhibition promotes adult hippocampal neurogenesis in vitro and in vivo." . ACS Chem Neurosci. 3(11): 963-971. (2012). (PMID: 23173075).
Susín, C. ; Morales-Garcia, J.A. ; Aguilar-Morante, D. ; Palomo, V.; Sanz-Sancristobal, M. ; Alonso-Gil, S. ; Gil, C.; Santos, A. ; Martinez, A.; Perez-Castillo, A. "The new iminothiadiazole derivative VP1.14 ameliorates hippocampal damage after an excitotoxic injury." . J. Neurochem.. 122(6): 1193-1202. (2012). (PMID: 22774807).
Redondo, M.; Brea, J.; Perez, D.I.; Soteras, I.; Val, C.; Perez, C.; Morales-García, J.A. ; Alonso-Gil, S. ; Paul-Fernandez, N.; Martin-Alvarez, R.; Cadavid, M.I.; Loza, M.I.; Perez-Castillo, A. ; Mengod, G.; Campillo, N.E.; Martinez, A.; Gil, C. "Effect of phosphodiesterase 7 (PDE7) inhibitors in experimental autoimmune encephalomyelitis mice. Discovery of a new chemically diverse family of compounds." . J. Med. Chem.. 55(7): 3274-3284. (2012). (PMID: 22385507).
Palomo, V.; Perez, D.I.; Perez, C.; Morales-Garcia, J.A. ; Soteras, I.; Alonso-Gil, S. ; Encinas, A.; Castro, A.; Campillo, N.E.; Perez-Castillo, A. ; Gil, C.; Martinez, A. "5-imino-1,2,4-thiadiazoles: first small molecules as substrate competitive inhibitors of glycogen synthase kinase 3." . J. Med. Chem.. 55(4): 1645-1661. (2012). (PMID: 22257026).
Morales-Garcia, J.A. ; Redondo, M.; Alonso-Gil, S. ; Gil, C.; Perez, C.; Martinez, A.; Santos, A. ; Perez-Castillo, A. "Phosphodiesterase 7 inhibition preserves dopaminergic neurons in cellular and rodent models of Parkinson disease." . PLoS ONE. 6(2): e17240. (2011). (PMID: 21390306).