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spacerTrabajos Publicados por Olivier Vincent -
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  1. Bueno-Arribas, M.; Vincent, O. "Identification of a novel mechanism for regulation of the early autophagy machinery assembly by PKA.". Autophagy Rep. 4(1): 2503226. (2025). (PMID: 40395985).
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  2. Bueno-Arribas, M.; Cruz-Cuevas, C.; Monforte-Martinez, B.; Navas, M.A.; Escalante, R.; Vincent, O. "The PKA signaling pathway regulates the association of the autophagy initiation complex with the lipidation machinery.". J Mol Biol. (): 168954. (2025). (PMID: 39826713).
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  3. Antón-Esteban, L.; Tornero-Écija, A.; Vincent, O.; Escalante, R. "Methods to Assess Autophagic Activity in Dictyostelium.". Methods Mol Biol. 2814(): 97-9106. (2024). (PMID: 38954200).
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  4. Bueno-Arribas, M.; Cruz-Cuevas, C.; Navas, M.A.; Escalante, R.; Vincent, O. "Coiled-coil-mediated dimerization of Atg16 is required for binding to the PROPPIN Atg21.". Open Biol. 13(11): 230192. (2023). (PMID: 37989223).
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  5. Tornero-Écija, A.; Zapata-Del-Baño, A.; Antón-Esteban, L.; Vincent, O.; Escalante, R. "The association of lipid transfer protein VPS13A with endosomes is mediated by sorting nexin SNX5.". Life Sci Alliance. 6(6): . (2023). (PMID: 36977596).
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  6. Tornero-Écija, A.R.; Navas, M.A.; Muñoz-Braceras, S.; Vincent, O.; Escalante, R. "Effect of rapamycin on lysosomal accumulation in a CRISPR/Cas9-based cellular model of VPS13A deficiency.". J Cell Mol Med. (): . (2023). (PMID: 37163371).
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  7. Vincent, O.; Antón-Esteban, L.; Bueno-Arribas, M.; Tornero-Écija, A.; Navas, M.Á.; Escalante, R. "The WIPI Gene Family and Neurodegenerative Diseases: Insights From Yeast and Dictyostelium Models.". Front Cell Dev Biol. 9(): 737071. (2021). (PMID: 34540850).
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  8. Bueno-Arribas, M.; Blanca, I.; Cruz-Cuevas, C.; Escalante, R.; Navas, M.A.; Vincent, O. "A conserved ATG2 binding site in WIPI4 and yeast Hsv2 is disrupted by mutations causing β-propeller protein-associated neurodegeneration.". Hum Mol Genet. (): . (2021). (PMID: 34368840).
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  9. Tornero-Écija, A.; Tábara, L.C.; Bueno-Arribas, M.; Antón-Esteban, L.; Navarro-Gómez, C.; Sánchez, I.; Vincent, O.; Escalante, R. "A Dictyostelium model for BPAN disease reveals a functional relationship between the WDR45/WIPI4 homolog Wdr45l and Vmp1 in the regulation of autophagy-associated PtdIns3P and ER stress.". Autophagy. (): 1-17. (2021). (PMID: 34328055).
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  10. Klionsky, D.J.; [ .., ].; Bartolome, A.; [ .., ].; Cuadrado, A.; [ .., ].; Escalante, R.; [ .., ].; García-Sanz, P.; [ .., ].; Lastres-Becker, I.; [ .., ].; León, Y.; [ .., ].; Martin-Sanz, P.; [ .., ].; Pajares, M.; [ .., ].; Rojo, A.I.; [ .., ].; Valverde, A.M.; [ .., ].; Varela-Nieto, I.; [ .., ].; Villalobo, A.; [ .., ].; Vincent, O.; [ .., ].; Tong, C.K. "Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition).". Autophagy. (): 1-382. (2021). (PMID: 33634751).
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  11. Vincent, O.; Gutierrez-Nogués, A.; Trejo-Herrero, A.; Navas, M.A. "A novel reverse two-hybrid method for the identification of missense mutations that disrupt protein-protein binding.". Sci Rep. 10(1): 21043. (2020). (PMID: 33273586).
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  12. Tábara, L.C.; Vincent, O.; Escalante, R. "Evidence for an evolutionary relationship between Vmp1 and bacterial DedA proteins.". Int. J. Dev. Biol.. 63(1-2): 67-71. (2019). (PMID: 30785211).
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  13. Muñoz-Braceras, S.; Tornero-Écija, A.R.; Vincent, O.; Escalante, R. "VPS13A is closely associated with mitochondria and is required for efficient lysosomal degradation.". Dis Model Mech. 12(2): . (2019). (PMID: 30709847).
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  14. Tábara, L.C.; Vicente, J.J.; Biazik, J.; Eskelinen, E.L.; Vincent, O.; Escalante, R. "Vacuole membrane protein 1 marks endoplasmic reticulum subdomains enriched in phospholipid synthesizing enzymes and is required for phosphoinositide distribution.". Traffic. 19(8): 624-638. (2018). (PMID: 29761602).
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  15. Gutierrez-Nogués, A.; García-Herrero, C.M.; Oriola, J.; Vincent, O.; Navas, M.A. "Functional characterization of MODY2 mutations in the nuclear export signal of glucokinase.". Biochim. Biophys. Acta. 1864(7): 2385-2394. (2018). (PMID: 29704611).
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  16. Domínguez-Martín, E.; Hernández-Elvira, M.; Vincent, O.; Coria, R.; Escalante, R. "Unfolding the Endoplasmic Reticulum of a Social Amoeba: Dictyostelium discoideum as a New Model for the Study of Endoplasmic Reticulum Stress.". Cells. 7(6): . (2018). (PMID: 29890774).
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  17. Domínguez-Martín, E.; Ongay-Larios, L.; Kawasaki, L.; Vincent, O.; Coello, G.; Coria, R.; Escalante, R. "IreA controls endoplasmic reticulum stress-induced autophagy and survival through homeostasis recovery.". Mol. Cell. Biol.. (): . (2018). (PMID: 29632077).
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  18. Mesquita, A.; Cardenal-Muñoz, E.; Dominguez, E.; Muñoz-Braceras, S.; Nuñez-Corcuera, B.; Phillips, B.A.; Tábara, L.C.; Xiong, Q.; Coria, R.; Eichinger, L.; Golstein, P.; King, J.S.; Soldati, T.; Vincent, O.; Escalante, R. "Autophagy in Dictyostelium: Mechanisms, regulation and disease in a simple biomedical model.". Autophagy. 13(1): 24-40. (2017). (PMID: 27715405).
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  19. Mesquita, A.; Tábara, L.C.; Martinez-Costa, O.; Santos-Rodrigo, N.; Vincent, O.; Escalante, R. "Dissecting the function of Atg1 complex in Dictyostelium autophagy reveals a connection with the pentose phosphate pathway enzyme transketolase.". Open Biol. 5(8): . (2015). (PMID: 26246495).
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  20. Herrador, A.; Livas, D.; Soletto, L.; Becuwe, M.; Léon, S.; Vincent, O. "Casein kinase 1 controls the activation threshold of an α-arrestin by multisite phosphorylation of the interdomain hinge.". Mol. Biol. Cell. (): . (2015). (PMID: 25851600).
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  21. Oriola, J.; Moreno, F.; Gutiérrez-Nogués, A.; León, S.; García-Herrero, C.M.; Vincent, O.; Navas, M.A. "Lack of glibenclamide response in a case of permanent neonatal diabetes caused by incomplete inactivation of glucokinase.". JIMD Rep. 20(): 21-26. (2015). (PMID: 25665835).
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  22. Herrador, A.; Léon, S.; Haguenauer-Tsapis, R.; Vincent, O. "A mechanism for protein monoubiquitination dependent on a trans-acting ubiquitin-binding domain.". J. Biol. Chem.. 288(23): 16206-16211. (2013). (PMID: 23645667).
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  23. Becuwe, M.; Herrador, A.; Haguenauer-Tsapis, R.; Vincent, O.; Léon, S. "Ubiquitin-mediated regulation of endocytosis by proteins of the arrestin family.". Biochem Res Int. 2012(): 242764. (2012). (PMID: 22988512).
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  24. Bañuelos, C.; García-Rivera, G.; López-Reyes, I.; Mendoza, L.; González-Robles, A.; Herranz, S.; Vincent, O.; Orozco, E. "EhADH112 is a Bro1 domain-containing protein involved in the Entamoeba histolytica multivesicular bodies pathway.". J. Biomed. Biotechnol.. 2012(): 657942. (2012). (PMID: 22500103).
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  25. Becuwe, M.; Vieira, N.; Lara, D.; Gomes-Rezende, J.; Soares-Cunha, C.; Casal, M.; Haguenauer-Tsapis, R.; Vincent, O.; Paiva, S.; Léon, S. "A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis.". J. Cell Biol.. 196(2): 247-259. (2012). (PMID: 22249293).
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  26. García-Herrero, C.M.; Rubio-Cabezas, O.; Azriel, S.; Gutierrez-Nogués, A.; Aragonés, A.; Vincent, O.; Campos-Barros, A.; Argente, J.; Navas, M.A. "Functional characterization of MODY2 mutations highlights the importance of the fine-tuning of glucokinase and its role in glucose sensing.". PLoS ONE. 7(1): e30518. (2012). (PMID: 22291974).
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  27. López-Reyes, I.; García-Rivera, G.; Bañuelos, C.; Herranz, S.; Vincent, O.; López-Camarillo, C.; Marchat, L.A.; Orozco, E. "Detection of the Endosomal Sorting Complex Required for Transport in Entamoeba histolytica and Characterization of the EhVps4 Protein.". J. Biomed. Biotechnol.. 2010(): 890674. (2010). (PMID: 20508821).
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  28. Herrador, A.; Herranz, S.; Lara, D.; Vincent, O. "Recruitment of the ESCRT machinery to a putative seven-transmembrane-domain receptor is mediated by an arrestin-related protein.". Mol. Cell. Biol.. 30(4): 897-907. (2010). (PMID: 20028738).
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  29. Galindo, A.; Hervás-Aguilar, A.; Rodríguez-Galán, O.; Vincent, O.; Arst, H.N.; Tilburn, J.; Peñalva, M.A. "PalC, one of two Bro1 domain proteins in the fungal pH signalling pathway, localizes to cortical structures and binds Vps32.". Traffic. 8(10): 1346-1364. (2007). (PMID: 17696968).
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  30. García-Herrero, C.M.; Galán, M.; Vincent, O.; Flández, B.; Gargallo, M.; Delgado-Alvarez, E.; Blázquez, E.; Navas, M.A. "Functional analysis of human glucokinase gene mutations causing MODY2: exploring the regulatory mechanisms of glucokinase activity.". Diabetologia. 50(2): 325-333. (2007). (PMID: 17186219).
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  31. Navas, M.A.; Galan, M.; Vincent, O.; Roncero, I.; Azriel, S.; Boix-Pallares, P.; Delgado-Alvarez, E.; Diaz-Cadórniga, F.; Blázquez, E. "Gene symbol: GCK. Disease: diabetes, MODY.". Hum. Genet.. 119(3): 363. (2006). (PMID: 17230658).
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  32. Galán, M.; Vincent, O.; Roncero, I.; Azriel, S.; Boix-Pallares, P.; Delgado-Alvarez, E.; Díaz-Cadórniga, F.; Blázquez, E.; Navas, M.A. "Effects of novel maturity-onset diabetes of the young (MODY)-associated mutations on glucokinase activity and protein stability.". Biochem J. 393(Pt 1): 389-396. (2006). (PMID: 16173921).
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  33. Chen, C.; Vincent, O.; Jin, J.; Weisz, O.A.; Montelaro, R.C. "Functions of early (AP-2) and late (AIP1/ALIX) endocytic proteins in equine infectious anemia virus budding.". J. Biol. Chem.. 280(49): 40474-40480. (2005). (PMID: 16215227).
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  34. Herranz, S.; Rodríguez, J.M.; Bussink, H.J.; Sánchez-Ferrero, J.C.; Arst, H.N.; Peñalva, M.A.; Vincent, O. "Arrestin-related proteins mediate pH signaling in fungi.". Proc Natl Acad Sci U S A. 102(34): 12141-12146. (2005). (PMID: 16099830).
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  35. Vincent, O.; Rainbow, L.; Tilburn, J.; Arst, H.N.; Peñalva, M.A. "YPXL/I is a protein interaction motif recognized by aspergillus PalA and its human homologue, AIP1/Alix.". Mol. Cell. Biol.. 23(5): 1647-1655. (2003). (PMID: 12588984).
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  36. Zaragoza, O.; Vincent, O.; Gancedo, J.M. "Regulatory elements in the FBP1 promoter respond differently to glucose-dependent signals in Saccharomyces cerevisiae.". Biochem. J.. 359(Pt 1): 193-201. (2001). (PMID: 11563983).
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  37. Vincent, O.; Kuchin, S.; Hong, S.P.; Townley, R.; Vyas, V.K.; Carlson, M. "Interaction of the Srb10 kinase with Sip4, a transcriptional activator of gluconeogenic genes in Saccharomyces cerevisiae.". Mol Cell Biol. 21(17): 5790-5796. (2001). (PMID: 11486018).
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  38. Vincent, O.; Townley, R.; Kuchin, S.; Carlson, M. "Subcellular localization of the Snf1 kinase is regulated by specific beta subunits and a novel glucose signaling mechanism.". Genes Dev.. 15(9): 1104-1114. (2001). (PMID: 11331606).
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  39. Enjalbert, B.; Parrou, J.L.; Vincent, O.; François, J. "Mitochondrial respiratory mutants of Saccharomyces cerevisiae accumulate glycogen and readily mobilize it in a glucose-depleted medium.". Microbiology (Reading, Engl.). 146 ( Pt 10)(): 2685-2694. (2000). (PMID: 11021944).
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  40. Vincent, O.; Carlson, M. "Gal83 mediates the interaction of the Snf1 kinase complex with the transcription activator Sip4.". EMBO J.. 18(23): 6672-6681. (1999). (PMID: 10581241).
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  41. Vincent, O.; Carlson, M. "Sip4, a Snf1 kinase-dependent transcriptional activator, binds to the carbon source-responsive element of gluconeogenic genes.". EMBO J.. 17(23): 7002-7008. (1998). (PMID: 9843506).
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  42. Vincent, O.; Gancedo, J.M. "Analysis of positive elements sensitive to glucose in the promoter of the FBP1 gene from yeast.". J. Biol. Chem.. 270(21): 12832-12838. (1995). (PMID: 7759539).
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  43. Vincent, O.; Gancedo, J.M. "Expression of a yeast gene can be blocked by insertion of short yeast DNA fragments between a UAS and the TATA box.". Curr. Genet.. 27(4): 387-389. (1995). (PMID: 7614563).
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  44. Mercado, J.J.; Vincent, O.; Gancedo, J.M. "Regions in the promoter of the yeast FBP1 gene implicated in catabolite repression may bind the product of the regulatory gene MIG1.". FEBS Lett.. 291(1): 97-9100. (1991). (PMID: 1657641).
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