Uribe, M.L.; Martín-Nieto, J.; Quereda, C.; Rubio-Fernández, M.; Cruces, J.; Janssen, G.M.C.; de Ru, A.H.; van Veelen, P.A.; Hensbergen, P.J. "Retinal Proteomics of a Mouse Model of Dystroglycanopathies Reveals Molecular Alterations in Photoreceptors.". J Proteome Res. (): . (2021). (PMID: 34027671).
Rubio-Fernández, M.; Uribe, M.L.; Vicente-Tejedor, J.; Germain, F.; Susín-Lara, C.; Quereda, C.; Montoliu, L.; de la Villa, P.; Martín-Nieto, J.; Cruces, J. "Impairment of photoreceptor ribbon synapses in a novel Pomt1 conditional knockout mouse model of dystroglycanopathy.". Sci Rep. 8(1): 8543. (2018). (PMID: 29867208).
Haro, C.; Uribe, M.L.; Quereda, C.; Cruces, J.; Martín-Nieto, J. "Expression in retinal neurons of fukutin and FKRP, the protein products of two dystroglycanopathy-causative genes.". Mol. Vis.. 24(): 43-58. (2018). (PMID: 29416295).
Izquierdo-Lahuerta, A.; de Luis, O.; Gómez-Esquer, F.; Cruces, J.; Coloma, A. "Gallus gallus orthologous to human alpha-dystroglycanopathies candidate genes: Gene expression and characterization during chicken embryogenesis.". Biochem. Biophys. Res. Commun.. 478(3): 1043-1048. (2016). (PMID: 27553274).
Uribe, M.L.; Haro, C.; Ventero, M.P.; Campello, L.; Cruces, J.; Martín-Nieto, J. "Expression pattern in retinal photoreceptors of POMGnT1, a protein involved in muscle-eye-brain disease.". Mol. Vis.. 22(): 658-673. (2016). (PMID: 27375352).
Raducu, M.; Cotarelo, R.P.; Simón, R.; Camacho, A.; Rubio-Fernández, M.; Hernández-Laín, A.; Cruces, J. "Clinical features and molecular characterization of a patient with muscle-eye-brain disease: a novel mutation in the POMGNT1 gene.". J. Child Neurol.. 29(2): 289-294. (2014). (PMID: 24282183).
Gomez Toledo, A.; Raducu, M.; Cruces, J.; Nilsson, J.; Halim, A.; Larson, G.; Rüetschi, U.; Grahn, A. "O-Mannose and O-N-acetyl galactosamine glycosylation of mammalian α-dystroglycan is conserved in a region-specific manner.". Glycobiology. 22(11): 1413-1423. (2012). (PMID: 22781125).
Raducu, M.; Baets, J.; Fano, O.; Van Coster, R.; Cruces, J. "Promoter alteration causes transcriptional repression of the POMGNT1 gene in limb-girdle muscular dystrophy type 2O.". Eur. J. Hum. Genet.. 20(9): 945-952. (2012). (PMID: 22419172).
de Lucas-Cerrillo, A.M.; Maldifassi, M.C.; Arnalich, F.; Renart, J.; Atienza, G.; Serantes, R.; Cruces, J.; Sánchez-Pacheco, A.; Andrés-Mateos, E.; Montiel, C. "Function of partially duplicated human α77 nicotinic receptor subunit CHRFAM7A gene: potential implications for the cholinergic anti-inflammatory response.". J. Biol. Chem.. 286(1): 594-606. (2011). (PMID: 21047781).
Lommel, M.; Willer, T.; Cruces, J.; Strahl, S. "POMT1 is essential for protein O-mannosylation in mammals.". Meth. Enzymol.. 479(): 323-342. (2010). (PMID: 20816174).
Cotarelo, R.P.; Fano, O.; Raducu, M.; Peña, A.; Tarilonte, P.; Mateos, F.; Simón, R.; Cabello, A.; Cruces, J. "A double homozygous mutation in the POMT1 gene involving exon skipping gives rise to Walker-Warburg syndrome in two Spanish Gypsy families.". Clin. Genet.. 76(1): 108-112. (2009). (PMID: 19519795).
Cotarelo, R.P.; Valero, M.C.; Prados, B.; Peña, A.; Rodríguez, L.; Fano, O.; Marco, J.J.; Martínez-Frías, M.L.; Cruces, J. "Two new patients bearing mutations in the fukutin gene confirm the relevance of this gene in Walker-Warburg syndrome.". Clin. Genet.. 73(2): 139-145. (2008). (PMID: 18177472).
Prados, B.; Peña, A.; Cotarelo, R.P.; Valero, M.C.; Cruces, J. "Expression of the murine Pomt1 gene in both the developing brain and adult muscle tissues and its relationship with clinical aspects of Walker-Warburg syndrome.". Am. J. Pathol.. 170(5): 1659-1668. (2007). (PMID: 17456771).
Andrés-Mateos, E.; Cruces, J.; Renart, J.; Solís-Garrido, L.M.; Serantes, R.; de Lucas-Cerrillo, A.M.; Montiel, C. "Bovine CACNA1A gene and comparative analysis of the CAG repeats associated to human spinocerebellar ataxia type-6.". Gene. 380(1): 54-61. (2006). (PMID: 16876337).
Andrés-Mateos, E.; Renart, J.; Cruces, J.; Solís-Garrido, L.M.; Serantes, R.; de Lucas-Cerrillo, A.M.; Aldea, M.; García, A.G.; Montiel, C. "Dynamic association of the Ca2+ channel alpha1A subunit and SNAP-25 in round or neurite-emitting chromaffin cells.". Eur. J. Neurosci.. 22(9): 2187-2198. (2005). (PMID: 16262657).
Martín-Villar, E.; Scholl, F.G.; Gamallo, C.; Yurrita, M.M.; Muñoz-Guerra, M.; Cruces, J.; Quintanilla, M. "Characterization of human PA2.26 antigen (T1alpha-2, podoplanin), a small membrane mucin induced in oral squamous cell carcinomas.". Int. J. Cancer. 113(6): 899-910. (2005). (PMID: 15515019).
Willer, T.; Prados, B.; Falcón-Pérez, J.M.; Renner-Müller, I.; Przemeck, G.K.; Lommel, M.; Coloma, A.; Valero, M.C.; de Angelis, M.H.; Tanner, W.; Wolf, E.; Strahl, S.; Cruces, J. "Targeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethality.". Proc. Natl. Acad. Sci. U.S.A.. 101(39): 14126-14131. (2004). (PMID: 15383666).
Beltrán-Valero de Bernabé, D.; Currier, S.; Steinbrecher, A.; Celli, J.; van Beusekom, E.; van der Zwaag, B.; Kayserili, H.; Merlini, L.; Chitayat, D.; Dobyns, W.B.; Cormand, B.; Lehesjoki, A.E.; Cruces, J.; Voit, T.; Walsh, C.A.; van Bokhoven, H.; Brunner, H.G. "Mutations in the O-mannosyltransferase gene POMT1 give rise to the severe neuronal migration disorder Walker-Warburg syndrome.". Am. J. Hum. Genet.. 71(5): 1033-1043. (2002). (PMID: 12369018).
De Juan, C.; Iniesta, P.; González-Quevedo, R.; Morán, A.; Sánchez-Pernaute, A.; Torres, A.J.; Balibrea, J.L.; Díaz-Rubio, E.; Cruces, J.; Benito, M. "Genomic organization of a novel glycosylphosphatidylinositol MAM gene expressed in human tissues and tumors.". Oncogene. 21(19): 3089-3094. (2002). (PMID: 12082541).
Valero, M.C.; de Luis, O.; Cruces, J.; Pérez Jurado, L.A. "Fine-scale comparative mapping of the human 7q11.23 region and the orthologous region on mouse chromosome 5G: the low-copy repeats that flank the Williams-Beuren syndrome deletion arose at breakpoint sites of an evolutionary inversion(s).". Genomics. 69(1): 1-13. (2000). (PMID: 11013070).
Pérez Jurado, L.A.; Wang, Y.K.; Francke, U.; Cruces, J. "TBL2, a novel transducin family member in the WBS deletion: characterization of the complete sequence, genomic structure, transcriptional variants and the mouse ortholog.". Cytogenet. Cell Genet.. 86(3-4): 277-284. (1999). (PMID: 10575226).
De Juan, C.; Iniesta, P.; Cruces, J.; Sanchez, A.; Massa, M.J.; Gonzalez-Quevedo, R.; Torres, A.J.; Balibrea, J.L.; Benito, M. "DNA amplification on chromosome 6p12 in non small cell lung cancer detected by arbitrarily primed polymerase chain reaction.". Int. J. Cancer. 84(4): 344-349. (1999). (PMID: 10404083).
Jurado, L.A.; Coloma, A.; Cruces, J. "Identification of a human homolog of the Drosophila rotated abdomen gene (POMT1) encoding a putative protein O-mannosyl-transferase, and assignment to human chromosome 9q34.1.". Genomics. 58(2): 171-180. (1999). (PMID: 10366449).
de la Puente, A.; Velasco, E.; Pérez Jurado, L.A.; Hernández-Chico, C.; van de Rijke, F.M.; Scherer, S.W.; Raap, A.K.; Cruces, J. "Analysis of the monomeric alphoid sequences in the pericentromeric region of human chromosome 7.". Cytogenet. Cell Genet.. 83(3-4): 176-181. (1998). (PMID: 10072574).
Cosgaya, J.M.; Aranda, A.; Cruces, J.; Martín-Blanco, E. "Neuronal differentiation of PC12 cells induced by engrailed homeodomain is DNA-binding specific and independent of MAP kinases.". J. Cell. Sci.. 111 ( Pt 16)(): 2377-2384. (1998). (PMID: 9683632).
Pérez Jurado, L.A.; Wang, Y.K.; Peoples, R.; Coloma, A.; Cruces, J.; Francke, U. "A duplicated gene in the breakpoint regions of the 7q11.23 Williams-Beuren syndrome deletion encodes the initiator binding protein TFII-I and BAP-135, a phosphorylation target of BTK.". Hum. Mol. Genet.. 7(3): 325-334. (1998). (PMID: 9466987).
Cruces, J.; Díaz-Guerra, M.; Gil, I.; Renart, J. "The 5S rRNA-histone repeat in the crustacean Artemia: structure, polymorphism and variation of the 5S rRNA segment in different populations.". Nucleic Acids Res.. 17(15): 6283-6297. (1989). (PMID: 2570403).
Gil, I.; Gallego, M.E.; Renart, J.; Cruces, J. "Identification of the transcriptional initiation site of ribosomal RNA genes in the crustacean Artemia.". Nucleic Acids Res.. 15(15): 6007-6016. (1987). (PMID: 3627976).
Díaz, V.; Quintanilla, M.; Cruces, J.; Renart, J.; Sebastián, J. "Immunological relationships between Artemia RNA polymerases and between RNA polymerases II from different eukaryotic organisms.". Mol. Cell. Biochem.. 76(2): 123-131. (1987). (PMID: 3118183).
Gallego, M.E.; Díaz-Guerra, M.; Cruces, J.; Sebastián, J.; Renart, J. "Characterization of two types of rRNA gene repeat units from the crustacean Artemia.". Gene. 48(1): 175-182. (1986). (PMID: 3557126).
Cruces, J.; Wonenburger, M.L.; Díaz-Guerra, M.; Sebastián, J.; Renart, J. "Satellite DNA in the crustacean Artemia.". Gene. 44(2-3): 341-345. (1986). (PMID: 3023196).
Cruces, J.; Diaz, V.; Quintanilla, M.; Renart, J.; Sebastian, J. "Purification and subunit structure of RNA polymerase II from different stages of Artemia development.". Eur. J. Biochem.. 141(2): 279-282. (1984). (PMID: 6734599).
Cruces, J.; Sebastián, J.; Renart, J. "Restriction mapping of the rRNA genes from Artemia larvae.". Biochem. Biophys. Res. Commun.. 98(2): 404-409. (1981). (PMID: 6261738).
Instituto de Investigaciones Biomédicas "Alberto Sols"
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