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spacerTrabajos Publicados por María Angeles Rodríguez Peña
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  1. Vidaurre, O.G.; Gascón, S.; Deogracias, R.; Sobrado, M.; Cuadrado, E.; Montaner, J.; Rodríguez-Peña, A.; Díaz-Guerra, M. "Imbalance of neurotrophin receptor isoforms TrkB-FL/TrkB-T1 induces neuronal death in excitotoxicity.". Cell Death Dis. 3(): e256. (2012). (PMID: 22258407).
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  2. López-Menéndez, C.; Gascón, S.; Sobrado, M.; Vidaurre, O.G.; Higuero, A.M.; Rodríguez-Peña, A.; Iglesias, T.; Díaz-Guerra, M. "Kidins220/ARMS downregulation by excitotoxic activation of NMDARs reveals its involvement in neuronal survival and death pathways.". J. Cell. Sci.. 122(Pt 19): 3554-3565. (2009). (PMID: 19759287).
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  3. Porlan, E.; Vidaurre, O.G.; Rodríguez-Peña, A. "Thyroid hormone receptor-beta (TR beta 1) impairs cell proliferation by the transcriptional inhibition of cyclins D1, E and A2.". Oncogene. 27(19): 2795-2800. (2008). (PMID: 18037966).
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  4. Gascón, S.; Sobrado, M.; Roda, J.M.; Rodríguez-Peña, A.; Díaz-Guerra, M. "Excitotoxicity and focal cerebral ischemia induce truncation of the NR2A and NR2B subunits of the NMDA receptor and cleavage of the scaffolding protein PSD-95.". Mol. Psychiatry. 13(1): 99-9114. (2008). (PMID: 17486105).
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  5. Gascón, S.; Deogracias, R.; Sobrado, M.; Roda, J.M.; Renart, J.; Rodríguez-Peña, A.; Díaz-Guerra, M. "Transcription of the NR1 subunit of the N-methyl-D-aspartate receptor is down-regulated by excitotoxic stimulation and cerebral ischemia.". J. Biol. Chem.. 280(41): 35018-35027. (2005). (PMID: 16049015).
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  6. Porlan, E.; Vega, S.; Iglesias, T.; Rodríguez-Peña, A. "Unliganded thyroid hormone receptor beta1 inhibits proliferation of murine fibroblasts by delaying the onset of the G1 cell-cycle signals.". Oncogene. 23(54): 8756-8765. (2004). (PMID: 15467737).
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  7. Deogracias, R.; Espliguero, G.; Iglesias, T.; Rodríguez-Peña, A. "Expression of the neurotrophin receptor trkB is regulated by the cAMP/CREB pathway in neurons.". Mol. Cell. Neurosci.. 26(3): 470-480. (2004). (PMID: 15234351).
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  8. Langley, K.; Hepp, R.; Grant, N.J.; Aunis, D.; Rodriguez-Pena, A. "Thyroid hormones regulate adrenal chromaffin cell SNAP-25.". Ann. N. Y. Acad. Sci.. 971(): 277-280. (2002). (PMID: 12438134).
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  9. Rodríguez-Peña, A.; Escrivá, H.; Handler, A.C.; Vallejo, C.G. "Thyroid hormone increases transcription of GA-binding protein/nuclear respiratory factor-2 alpha-subunit in rat liver.". FEBS Lett.. 514(2-3): 309-314. (2002). (PMID: 11943172).
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  10. Bury, F.; Carré, J.L.; Vega, S.; Ghandour, M.S.; Rodriguez-Peña, A.; Langley, K.; Sarliève, L.L. "Coexpression of thyroid hormone receptor isoforms in mouse oligodendrocytes.". J. Neurosci. Res.. 67(1): 106-113. (2002). (PMID: 11754086).
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  11. Vallejo, C.G.; Escrivá, H.; Rodríguez-Peña, A. "Evidence of tissue-specific, post-transcriptional regulation of NRF-2 expression.". Biochimie. 82(12): 1129-1133. (2000). (PMID: 11120355).
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  12. Pombo, P.M.; Barettino, D.; Espliguero, G.; Metsis, M.; Iglesias, T.; Rodriguez-Pena, A. "Transcriptional repression of neurotrophin receptor trkB by thyroid hormone in the developing rat brain.". J. Biol. Chem.. 275(48): 37510-37517. (2000). (PMID: 10978336).
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  13. Meng, K.; Rodriguez-Peña, A.; Dimitrov, T.; Chen, W.; Yamin, M.; Noda, M.; Deuel, T.F. "Pleiotrophin signals increased tyrosine phosphorylation of beta beta-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase beta/zeta.". Proc. Natl. Acad. Sci. U.S.A.. 97(6): 2603-2608. (2000). (PMID: 10706604).
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  14. Escrivá, H.; Rodríguez-Peña, A.; Vallejo, C.G. "Expression of mitochondrial genes and of the transcription factors involved in the biogenesis of mitochondria Tfam, NRF-1 and NRF-2, in rat liver, testis and brain.". Biochimie. 81(10): 965-971. (1999). (PMID: 10575350).
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  15. Rodríguez-Peña, A. "Oligodendrocyte development and thyroid hormone.". J. Neurobiol.. 40(4): 497-512. (1999). (PMID: 10453052).
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  16. Barettino, D.; Pombo, P.M.; Espliguero, G.; Rodríguez-Peña, A. "The mouse neurotrophin receptor trkB gene is transcribed from two different promoters.". Biochim. Biophys. Acta. 1446(1-2): 24-34. (1999). (PMID: 10395916).
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  17. Pombo, P.M.; Barettino, D.; Ibarrola, N.; Vega, S.; Rodríguez-Peña, A. "Stimulation of the myelin basic protein gene expression by 9-cis-retinoic acid and thyroid hormone: activation in the context of its native promoter.". Brain Res. Mol. Brain Res.. 64(1): 92-9100. (1999). (PMID: 9889331).
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  18. Carré, J.L.; Demerens, C.; Rodríguez-Peña, A.; Floch, H.H.; Vincendon, G.; Sarliève, L.L. "Thyroid hormone receptor isoforms are sequentially expressed in oligodendrocyte lineage cells during rat cerebral development.". J. Neurosci. Res.. 54(5): 584-594. (1998). (PMID: 9843149).
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  19. Pombo, P.M.; Ibarrola, N.; Alonso, M.A.; Rodríguez-Peña, A. "Thyroid hormone regulates the expression of the MAL proteolipid, a component of glycolipid-enriched membranes, in neonatal rat brain.". J. Neurosci. Res.. 52(5): 584-590. (1998). (PMID: 9632314).
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  20. Ibarrola, N.; Mayer-Pröschel, M.; Rodriguez-Peña, A.; Noble, M. "Evidence for the existence of at least two timing mechanisms that contribute to oligodendrocyte generation in vitro.". Dev. Biol.. 180(1): 1-21. (1996). (PMID: 8948570).
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  21. Frade, J.M.; Martí, E.; Bovolenta, P.; Rodríguez-Peña, M.A.; Pérez-García, D.; Rohrer, H.; Edgar, D.; Rodríguez-Tébar, A. "Insulin-like growth factor-I stimulates neurogenesis in chick retina by regulating expression of the alpha 6 integrin subunit.". Development. 122(8): 2497-2506. (1996). (PMID: 8756294).
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  22. Bovolenta, P.; Frade, J.M.; Martí, E.; Rodríguez-Peña, M.A.; Barde, Y.A.; Rodríguez-Tébar, A. "Neurotrophin-3 antibodies disrupt the normal development of the chick retina.". J. Neurosci.. 16(14): 4402-4410. (1996). (PMID: 8699251).
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  23. Rodríguez-Peña, A.; Botana, M.; González, M.; Requejo, F. "Expression of neurotrophins and their receptors in sciatic nerve of experimentally diabetic rats.". Neurosci. Lett.. 200(1): 37-40. (1995). (PMID: 8584261).
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  24. Iglesias, T.; Llanos, S.; López-Barahona, M.; Seliger, B.; Rodríguez-Peña, A.; Bernal, J.; Muñoz, A. "Induction of platelet-derived growth factor B/c-sis by the v-erbA oncogene in glial cells.". Oncogene. 10(6): 1103-1110. (1995). (PMID: 7700635).
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  25. Iñiguez, M.A.; Morte, B.; Rodriguez-Peña, A.; Muñoz, A.; Gerendasy, D.; Sutcliffe, J.G.; Bernal, J. "Characterization of the promoter region and flanking sequences of the neuron-specific gene RC3 (neurogranin).". Brain Res. Mol. Brain Res.. 27(2): 205-214. (1994). (PMID: 7898304).
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  26. Alvarez-Dolado, M.; Iglesias, T.; Rodríguez-Peña, A.; Bernal, J.; Muñoz, A. "Expression of neurotrophins and the trk family of neurotrophin receptors in normal and hypothyroid rat brain.". Brain Res. Mol. Brain Res.. 27(2): 249-257. (1994). (PMID: 7898308).
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  27. Iglesias, T.; Llanos, S.; López-Barahona, M.; Pérez-Aranda, A.; Rodríguez-Peña, A.; Bernal, J.; Höhne, A.; Seliger, B.; Muñoz, A. "c-erbA and v-erbA modulate growth and gene expression of a mouse glial precursor cell line.". Cell Growth Differ.. 5(7): 697-704. (1994). (PMID: 7947384).
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  28. López-Barahona, M.; Miñano, M.; Mira, E.; Iglesias, T.; Stunnenberg, H.G.; Rodríguez-Peña, A.; Bernal, J.; Muñoz, A. "Retinoic acid posttranscriptionally up-regulates proteolipid protein gene expression in C6 glioma cells.". J. Biol. Chem.. 268(34): 25617-25623. (1993). (PMID: 7503983).
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  29. García-Fernández, L.F.; Iñiguez, M.A.; Rodríguez-Peña, A.; Muñoz, A.; Bernal, J. "Brain-specific prostaglandin D2 synthetase mRNA is dependent on thyroid hormone during rat brain development.". Biochem. Biophys. Res. Commun.. 196(1): 396-401. (1993). (PMID: 8216319).
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  30. Iñiguez, M.A.; Rodriguez-Peña, A.; Ibarrola, N.; Aguilera, M.; Muñoz, A.; Bernal, J. "Thyroid hormone regulation of RC3, a brain-specific gene encoding a protein kinase-C substrate.". Endocrinology. 133(2): 467-473. (1993). (PMID: 8344193).
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  31. Rodriguez-Peña, A.; Ibarrola, N.; Iñiguez, M.A.; Muñoz, A.; Bernal, J. "Neonatal hypothyroidism affects the timely expression of myelin-associated glycoprotein in the rat brain.". J. Clin. Invest.. 91(3): 812-818. (1993). (PMID: 7680668).
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  32. Bernal, J.; Rodriguez-Pena, A.; Iniguez, M.A.; Ibarrola, N.; Munoz, A. "Influence of thyroid hormone on brain gene expression.". Acta Med. Austriaca. 19 Suppl 1(): 32-35. (1992). (PMID: 1519449).
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  33. Muñoz, A.; Rodriguez-Peña, A.; Perez-Castillo, A.; Ferreiro, B.; Sutcliffe, J.G.; Bernal, J. "Effects of neonatal hypothyroidism on rat brain gene expression.". Mol. Endocrinol.. 5(2): 273-280. (1991). (PMID: 1710032).
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  34. Obregón, M.J.; Santisteban, P.; Rodríguez-Peña, A.; Pascual, A.; Cartagena, P.; Ruiz-Marcos, A.; Lamas, L.; Escobar del Rey, F.; Morreale de Escobar, G. "Cerebral hypothyroidism in rats with adult-onset iodine deficiency.". Endocrinology. 115(2): 614-624. (1984). (PMID: 6745172).
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  35. Santisteban, P.; Obregon, M.J.; Rodriguez-Peña, A.; Lamas, L.; Del Rey, F.E.; De Escobar, G.M. "Are iodine-deficient rats euthyroid?". Endocrinology. 110(5): 1780-1789. (1982). (PMID: 6804212).
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