Publications

All our publications

*Listed are the articles found in the PubMed database.

Publications by “Cristina Rodríguez González de Antona”

Deubiquitinase USP9X loss sensitizes renal cancer cells to mTOR inhibition.

Roldán-Romero, JM, Valdivia, C, Santos, M, Lanillos, J, Maroto, P, Anguera, G, Calsina, B, Martinez-Montes, A, Monteagudo, M, Mellid, S, Leandro-García, LJ, Montero-Conde, C , Cascón, A, Roncador, G, Coloma, J, Robledo, M, Rodriguez-Antona, C .

DLST mutations in pheochromocytoma and paraganglioma cause proteome hyposuccinylation and metabolic remodeling.

Mellid, S, García, F, Leandro-García, LJ, Díaz-Talavera, A, Martínez-Montes, ÁM, Gil, E, Calsina, B, Monteagudo, M, Letón, R, Roldán-Romero, JM, Santos, M, Lanillos, J, Valdivia, C, Martínez-Puente, N, de Nicolás-Hernández, J, Jiménez, S, Pérez-Martínez, M, Honrado, E, Coloma, J, Cerezo, A, Santiveri, CM, Esteller, M, Campos-Olivas, R, Caleiras, E, Montero-Conde, C , Rodríguez-Antona, C , Muñoz, J, Robledo, M, Cascón, A.

Clinical parameters affecting survival outcomes in patients with low-grade serous ovarian carcinoma: an international multicentre analysis.

May, T, Bernardini, M, Lheureux, S, Aben, KKH, Bandera, EV, Beckmann, MW, Benitez, J, Berchuck, A, Bjørge, L, Carney, ME, Cramer, DW, deFazio, A, Dörk, T, Eccles, DM, Friedlander, M, García, MJ, Goode, EL, Hein, A, Høgdall, CK, Jensen, A, Johnatty, S, Kennedy, CJ, Kiemeney, LA, Kjær, SK, Kupryjańczyk, J, Matsuo, K, McGuire, V, Modugno, F, Paddock, LE, Pejovic, T, Phelan, CM, Riggan, MJ, Rodriguez-Antona, C , Rothstein, JH, Sieh, W, Song, H, Terry, KL, van Altena, AM, Vanderstichele, A, Vergote, I, Thomsen, LCV, Webb, PM, Wentzensen, N, Wilkens, LR, Ziogas, A, Jiang, H, Tone, A, , .

PBRM1 and KDM5C cooperate to define high-angiogenesis tumors and increased antiangiogenic response in renal cancer.

Santos, M, Lanillos, J, Caleiras, E, Valdivia, C, Roldan-Romero, JM, Laínez, N, Puente, J, Beuselinck, B, Oudard, S, Zucman-Rossi, J, Navarro, P, Robledo, M, Castellano, D, de Velasco, G, García-Donas, J, Rodriguez-Antona, C .

Tumour mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade.

Mahmood, M, Liu, EM, Shergold, AL, Tolla, E, Tait-Mulder, J, Huerta Uribe, A, Shokry, E, Young, AL, Lilla, S, Kim, M, Park, T, Manchon, JL, Rodríguez-Antona, C , Walters, RC, Springett, RJ, Blaza, JN, Zanivan, S, Sumpton, D, Roberts, EW, Reznik, E, Gammage, PA.

CCNE1 and survival of patients with tubo-ovarian high-grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study.

Kang, EY, Weir, A, Meagher, NS, Farrington, K, Nelson, GS, Ghatage, P, Lee, CH, Riggan, MJ, Bolithon, A, Popovic, G, Leung, B, Tang, K, Lambie, N, Millstein, J, Alsop, J, Anglesio, MS, Ataseven, B, Barlow, E, Beckmann, MW, Berger, J, Bisinotto, C, Bösmüller, H, Boros, J, Brand, AH, Brooks-Wilson, A, Brucker, SY, Carney, ME, Casablanca, Y, Cazorla-Jiménez, A, Cohen, PA, Conrads, TP, Cook, LS, Coulson, P, Courtney-Brooks, M, Cramer, DW, Crowe, P, Cunningham, JM, Cybulski, C, Darcy, KM, El-Bahrawy, MA, Elishaev, E, Erber, R, Farrell, R, Fereday, S, Fischer, A, García, MJ, Gayther, SA, Gentry-Maharaj, A, Gilks, CB, , , Grube, M, Harnett, PR, Harrington, SP, Harter, P, Hartmann, A, Hecht, JL, Heikaus, S, Hein, A, Heitz, F, Hendley, J, Hernandez, BY, Polo, SH, Heublein, S, Hirasawa, A, Høgdall, E, Høgdall, CK, Horlings, HM, Huntsman, DG, Huzarski, T, Jewell, A, Jimenez-Linan, M, Jones, ME, Kaufmann, SH, Kennedy, CJ, Khabele, D, Kommoss, FKF, Kruitwagen, RFPM, Lambrechts, D, Le, ND, Lener, M, Lester, J, Leung, Y, Linder, A, Loverix, L, Lubiński, J, Madan, R, Maxwell, GL, Modugno, F, Neuhausen, SL, Olawaiye, A, Olbrecht, S, Orsulic, S, Palacios, J, Pearce, CL, Pike, MC, Quinn, CM, Mohan, GR, Rodríguez-Antona, C , Ruebner, M, Ryan, A, Salfinger, SG, Sasamoto, N, Schildkraut, JM, Schoemaker, MJ, Shah, M, Sharma, R, Shvetsov, YB, Singh, N, Sonke, GS, Steele, L, Stewart, CJR, Sundfeldt, K, Swerdlow, AJ, Talhouk, A, Tan, A, Taylor, SE, Terry, KL, Tołoczko, A, Traficante, N, Van de Vijver, KK, van der Aa, MA, Van Gorp, T, Van Nieuwenhuysen, E, van-Wagensveld, L, Vergote, I, Vierkant, RA, Wang, C, Wilkens, LR, Winham, SJ, Wu, AH, Benitez, J, Berchuck, A, Candido Dos Reis, FJ, DeFazio, A, Fasching, PA, Goode, EL, Goodman, MT, Gronwald, J, Karlan, BY, Kommoss, S, Menon, U, Sinn, HP, Staebler, A, Brenton, JD, Bowtell, DD, Pharoah, PDP, Ramus, SJ, Köbel, M.

Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma.

Calsina, B, Piñeiro-Yáñez, E, Martínez-Montes, ÁM, Caleiras, E, Fernández-Sanromán, Á, Monteagudo, M, Torres-Pérez, R, Fustero-Torre, C, Pulgarín-Alfaro, M, Gil, E, Letón, R, Jiménez, S, García-Martín, S, Martin, MC, Roldán-Romero, JM, Lanillos, J, Mellid, S, Santos, M, Díaz-Talavera, A, Rubio, Á, González, P, Hernando, B, Bechmann, N, Dona, M, Calatayud, M, Guadalix, S, Álvarez-Escolá, C, Regojo, RM, Aller, J, Del Olmo-Garcia, MI, López-Fernández, A, Fliedner, SMJ, Rapizzi, E, Fassnacht, M, Beuschlein, F, Quinkler, M, Toledo, RA, Mannelli, M, Timmers, HJ, Eisenhofer, G, Rodríguez-Perales, S, Domínguez, O, Macintyre, G, Currás-Freixes, M, Rodríguez-Antona, C , Cascón, A, Leandro-García, LJ, Montero-Conde, C , Roncador, G, García-García, JF, Pacak, K, Al-Shahrour, F, Robledo, M.

PharmVar GeneFocus: CYP3A5.

Rodriguez-Antona, C , Savieo, JL, Lauschke, VM, Sangkuhl, K, Drögemöller, BI, Wang, D, van Schaik, RHN, Gilep, AA, Peter, AP, Boone, EC, Ramey, BE, Klein, TE, Whirl-Carrillo, M, Pratt, VM, Gaedigk, A.

Interrogating the Significance of PARP1 Expression and PBRM1 Mutation as Biomarkers for Predicting the Response to Atezolizumab plus Bevacizumab or to Sunitinib in Patients with Clear Cell Renal Cell Carcinoma.

Lanillos, J, Santos, M, Valdivia, C, Mora, A, Rodríguez-Antona, C .

Comprehensive molecular analysis of immortalization hallmarks in thyroid cancer reveals new prognostic markers.

Montero-Conde, C , Leandro-García, LJ, Martínez-Montes, ÁM, Martínez, P, Moya, FJ, Letón, R, Gil, E, Martínez-Puente, N, Guadalix, S, Currás-Freixes, M, García-Tobar, L, Zafon, C, Jordà, M, Riesco-Eizaguirre, G , González-García, P, Monteagudo, M, Torres-Pérez, R, Mancikova, V, Ruiz-Llorente, S , Pérez-Martínez, M, Pita, G, Galofré, JC, Gonzalez-Neira, A, Cascón, A, Rodríguez-Antona, C , Megías, D, Blasco, MA, Caleiras, E, Rodríguez-Perales, S, Robledo, M.

Single-nucleotide polymorphism associations with efficacy and toxicity in metastatic castration-resistant prostate cancer treated with cabazitaxel.

Herrero Rivera, D, Vacas, CG, Kovandzic, LM, Vázquez, JP, Alonso, LA, González, BM, Aragón, VC, Grande, E, Caro, RL, Virizuela Echaburu, JA, Rodríguez Moreno, JF, Etxebarria, AA, Rodríguez-Antona, C , Durán, I.

Genome-Wide Meta-Analysis Identifies Variants in DSCAM and PDLIM3 That Correlate with Efficacy Outcomes in Metastatic Renal Cell Carcinoma Patients Treated with Sunitinib.

Diekstra, MHM, Swen, JJ, van der Zanden, LFM, Vermeulen, SH, Boven, E, Mathijssen, RHJ, Fukunaga, K, Mushiroda, T, Hongo, F, Oosterwijk, E, Cambon-Thomsen, A, Castellano, D, Fritsch, A, Donas, JG, Rodriguez-Antona, C , Ruijtenbeek, R, Radu, MT, Eisen, T, Junker, K, Roessler, M, Jaehde, U, Miki, T, Böhringer, S, Kubo, M, Kiemeney, LALM, Guchelaar, HJ.

Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk.

Dareng, EO, Tyrer, JP, Barnes, DR, Jones, MR, Yang, X, Aben, KKH, Adank, MA, Agata, S, Andrulis, IL, Anton-Culver, H, Antonenkova, NN, Aravantinos, G, Arun, BK, Augustinsson, A, Balmaña, J, Bandera, EV, Barkardottir, RB, Barrowdale, D, Beckmann, MW, Beeghly-Fadiel, A, Benitez, J, Bermisheva, M, Bernardini, MQ, Bjorge, L, Black, A, Bogdanova, NV, Bonanni, B, Borg, A, Brenton, JD, Budzilowska, A, Butzow, R, Buys, SS, Cai, H, Caligo, MA, Campbell, I, Cannioto, R, Cassingham, H, Chang-Claude, J, Chanock, SJ, Chen, K, Chiew, YE, Chung, WK, Claes, KBM, Colonna, S, , , , , , , Cook, LS, Couch, FJ, Daly, MB, Dao, F, Davies, E, de la Hoya, M, de Putter, R, Dennis, J, DePersia, A, Devilee, P, Diez, O, Ding, YC, Doherty, JA, Domchek, SM, Dörk, T, du Bois, A, Dürst, M, Eccles, DM, Eliassen, HA, Engel, C, Evans, GD, Fasching, PA, Flanagan, JM, Fortner, RT, Machackova, E, Friedman, E, Ganz, PA, Garber, J, Gensini, F, Giles, GG, Glendon, G, Godwin, AK, Goodman, MT, Greene, MH, Gronwald, J, , , , , Hahnen, E, Haiman, CA, Håkansson, N, Hamann, U, Hansen, TVO, Harris, HR, Hartman, M, Heitz, F, Hildebrandt, MAT, Høgdall, E, Høgdall, CK, Hopper, JL, Huang, RY, Huff, C, Hulick, PJ, Huntsman, DG, Imyanitov, EN, , , , , Isaacs, C, Jakubowska, A, James, PA, Janavicius, R, Jensen, A, Johannsson, OT, John, EM, Jones, ME, Kang, D, Karlan, BY, Karnezis, A, Kelemen, LE, Khusnutdinova, E, Kiemeney, LA, Kim, BG, Kjaer, SK, Komenaka, I, Kupryjanczyk, J, Kurian, AW, Kwong, A, Lambrechts, D, Larson, MC, Lazaro, C, Le, ND, Leslie, G, Lester, J, Lesueur, F, Levine, DA, Li, L, Li, J, Loud, JT, Lu, KH, Lubiński, J, Mai, PL, Manoukian, S, Marks, JR, Matsuno, RK, Matsuo, K, May, T, McGuffog, L, McLaughlin, JR, McNeish, IA, Mebirouk, N, Menon, U, Miller, A, Milne, RL, Minlikeeva, A, Modugno, F, Montagna, M, Moysich, KB, Munro, E, Nathanson, KL, Neuhausen, SL, Nevanlinna, H, Yie, JNY, Nielsen, HR, Nielsen, FC, Nikitina-Zake, L, Odunsi, K, Offit, K, Olah, E, Olbrecht, S, Olopade, OI, Olson, SH, Olsson, H, Osorio, A, Papi, L, Park, SK, Parsons, MT, Pathak, H, Pedersen, IS, Peixoto, A, Pejovic, T, Perez-Segura, P, Permuth, JB, Peshkin, B, Peterlongo, P, Piskorz, A, Prokofyeva, D, Radice, P, Rantala, J, Riggan, MJ, Risch, HA, Rodriguez-Antona, C , Ross, E, Rossing, MA, Runnebaum, I, Sandler, DP, Santamariña, M, Soucy, P, Schmutzler, RK, Setiawan, VW, Shan, K, Sieh, W, Simard, J, Singer, CF, Sokolenko, AP, Song, H, Southey, MC, Steed, H, Stoppa-Lyonnet, D, Sutphen, R, Swerdlow, AJ, Tan, YY, Teixeira, MR, Teo, SH, Terry, KL, Terry, MB, , , , , Thomassen, M, Thompson, PJ, Thomsen, LCV, Thull, DL, Tischkowitz, M, Titus, L, Toland, AE, Torres, D, Trabert, B, Travis, R, Tung, N, Tworoger, SS, Valen, E, van Altena, AM, van der Hout, AH, Van Nieuwenhuysen, E, van Rensburg, EJ, Vega, A, Edwards, DV, Vierkant, RA, Wang, F, Wappenschmidt, B, Webb, PM, Weinberg, CR, Weitzel, JN, Wentzensen, N, White, E, Whittemore, AS, Winham, SJ, Wolk, A, Woo, YL, Wu, AH, Yan, L, Yannoukakos, D, Zavaglia, KM, Zheng, W, Ziogas, A, Zorn, KK, Kleibl, Z, Easton, D, Lawrenson, K, DeFazio, A, Sellers, TA, Ramus, SJ, Pearce, CL, Monteiro, AN, Cunningham, J, Goode, EL, Schildkraut, JM, Berchuck, A, Chenevix-Trench, G, Gayther, SA, Antoniou, AC, Pharoah, PDP.

Polygenic risk modeling for prediction of epithelial ovarian cancer risk.

Dareng, EO, Tyrer, JP, Barnes, DR, Jones, MR, Yang, X, Aben, KKH, Adank, MA, Agata, S, Andrulis, IL, Anton-Culver, H, Antonenkova, NN, Aravantinos, G, Arun, BK, Augustinsson, A, Balmaña, J, Bandera, EV, Barkardottir, RB, Barrowdale, D, Beckmann, MW, Beeghly-Fadiel, A, Benitez, J, Bermisheva, M, Bernardini, MQ, Bjorge, L, Black, A, Bogdanova, NV, Bonanni, B, Borg, A, Brenton, JD, Budzilowska, A, Butzow, R, Buys, SS, Cai, H, Caligo, MA, Campbell, I, Cannioto, R, Cassingham, H, Chang-Claude, J, Chanock, SJ, Chen, K, Chiew, YE, Chung, WK, Claes, KBM, Colonna, S, , , , , , , Cook, LS, Couch, FJ, Daly, MB, Dao, F, Davies, E, de la Hoya, M, de Putter, R, Dennis, J, DePersia, A, Devilee, P, Diez, O, Ding, YC, Doherty, JA, Domchek, SM, Dörk, T, du Bois, A, Dürst, M, Eccles, DM, Eliassen, HA, Engel, C, Evans, GD, Fasching, PA, Flanagan, JM, Fortner, RT, Machackova, E, Friedman, E, Ganz, PA, Garber, J, Gensini, F, Giles, GG, Glendon, G, Godwin, AK, Goodman, MT, Greene, MH, Gronwald, J, , , , , Hahnen, E, Haiman, CA, Håkansson, N, Hamann, U, Hansen, TVO, Harris, HR, Hartman, M, Heitz, F, Hildebrandt, MAT, Høgdall, E, Høgdall, CK, Hopper, JL, Huang, RY, Huff, C, Hulick, PJ, Huntsman, DG, Imyanitov, EN, , , , , Isaacs, C, Jakubowska, A, James, PA, Janavicius, R, Jensen, A, Johannsson, OT, John, EM, Jones, ME, Kang, D, Karlan, BY, Karnezis, A, Kelemen, LE, Khusnutdinova, E, Kiemeney, LA, Kim, BG, Kjaer, SK, Komenaka, I, Kupryjanczyk, J, Kurian, AW, Kwong, A, Lambrechts, D, Larson, MC, Lazaro, C, Le, ND, Leslie, G, Lester, J, Lesueur, F, Levine, DA, Li, L, Li, J, Loud, JT, Lu, KH, Lubiński, J, Mai, PL, Manoukian, S, Marks, JR, Matsuno, RK, Matsuo, K, May, T, McGuffog, L, McLaughlin, JR, McNeish, IA, Mebirouk, N, Menon, U, Miller, A, Milne, RL, Minlikeeva, A, Modugno, F, Montagna, M, Moysich, KB, Munro, E, Nathanson, KL, Neuhausen, SL, Nevanlinna, H, Yie, JNY, Nielsen, HR, Nielsen, FC, Nikitina-Zake, L, Odunsi, K, Offit, K, Olah, E, Olbrecht, S, Olopade, OI, Olson, SH, Olsson, H, Osorio, A, Papi, L, Park, SK, Parsons, MT, Pathak, H, Pedersen, IS, Peixoto, A, Pejovic, T, Perez-Segura, P, Permuth, JB, Peshkin, B, Peterlongo, P, Piskorz, A, Prokofyeva, D, Radice, P, Rantala, J, Riggan, MJ, Risch, HA, Rodriguez-Antona, C , Ross, E, Rossing, MA, Runnebaum, I, Sandler, DP, Santamariña, M, Soucy, P, Schmutzler, RK, Setiawan, VW, Shan, K, Sieh, W, Simard, J, Singer, CF, Sokolenko, AP, Song, H, Southey, MC, Steed, H, Stoppa-Lyonnet, D, Sutphen, R, Swerdlow, AJ, Tan, YY, Teixeira, MR, Teo, SH, Terry, KL, Terry, MB, , , , , Thomassen, M, Thompson, PJ, Thomsen, LCV, Thull, DL, Tischkowitz, M, Titus, L, Toland, AE, Torres, D, Trabert, B, Travis, R, Tung, N, Tworoger, SS, Valen, E, van Altena, AM, van der Hout, AH, Van Nieuwenhuysen, E, van Rensburg, EJ, Vega, A, Edwards, DV, Vierkant, RA, Wang, F, Wappenschmidt, B, Webb, PM, Weinberg, CR, Weitzel, JN, Wentzensen, N, White, E, Whittemore, AS, Winham, SJ, Wolk, A, Woo, YL, Wu, AH, Yan, L, Yannoukakos, D, Zavaglia, KM, Zheng, W, Ziogas, A, Zorn, KK, Kleibl, Z, Easton, D, Lawrenson, K, DeFazio, A, Sellers, TA, Ramus, SJ, Pearce, CL, Monteiro, AN, Cunningham, J, Goode, EL, Schildkraut, JM, Berchuck, A, Chenevix-Trench, G, Gayther, SA, Antoniou, AC, Pharoah, PDP.

Considerations on diagnosis and surveillance measures of PTEN hamartoma tumor syndrome: clinical and genetic study in a series of Spanish patients.

Pena-Couso, L, Ercibengoa, M, Mercadillo, F, Gómez-Sánchez, D, Inglada-Pérez, L, Santos, M, Lanillos, J, Gutiérrez-Abad, D, Hernández, A, Carbonell, P, Letón, R, Robledo, M, Rodríguez-Antona, C , Perea, J, Urioste, M, , .

Clinical Pharmacogenetics Implementation Consortium Guideline for the Use of Aminoglycosides Based on MT-RNR1 Genotype.

McDermott, JH, Wolf, J, Hoshitsuki, K, Huddart, R, Caudle, KE, Whirl-Carrillo, M, Steyger, PS, Smith, RJH, Cody, N, Rodriguez-Antona, C , Klein, TE, Newman, WG.

Sunitinib and Evofosfamide (TH-302) in Systemic Treatment-Naïve Patients with Grade 1/2 Metastatic Pancreatic Neuroendocrine Tumors: The GETNE-1408 Trial.

Grande, E, Rodriguez-Antona, C , López, C, Alonso-Gordoa, T, Benavent, M, Capdevila, J, Teulé, A, Custodio, A, Sevilla, I , Hernando, J, Gajate, P, Molina-Cerrillo, J, Díez, JJ, Santos, M, Lanillos, J, García-Carbonero, R.

Analysis of Telomere Maintenance Related Genes Reveals NOP10 as a New Metastatic-Risk Marker in Pheochromocytoma/Paraganglioma.

Monteagudo, M, Martínez, P, Leandro-García, LJ, Martínez-Montes, ÁM, Calsina, B, Pulgarín-Alfaro, M, Díaz-Talavera, A, Mellid, S, Letón, R, Gil, E, Pérez-Martínez, M, Megías, D, Torres-Ruiz, R, Rodriguez-Perales, S, González, P, Caleiras, E, Jiménez-Villa, S, Roncador, G, Álvarez-Escolá, C, Regojo, RM, Calatayud, M, Guadalix, S, Currás-Freixes, M, Rapizzi, E, Canu, L, Nölting, S, Remde, H, Fassnacht, M, Bechmann, N, Eisenhofer, G, Mannelli, M, Beuschlein, F, Quinkler, M, Rodríguez-Antona, C , Cascón, A, Blasco, MA, Montero-Conde, C , Robledo, M.

MicroRNAs Targeting HIF-2α, VEGFR1 and/or VEGFR2 as Potential Predictive Biomarkers for VEGFR Tyrosine Kinase and HIF-2α Inhibitors in Metastatic Clear-Cell Renal Cell Carcinoma.

Kinget, L, Roussel, E, Verbiest, A, Albersen, M, Rodríguez-Antona, C , Graña-Castro, O, Inglada-Pérez, L, Zucman-Rossi, J, Couchy, G, Job, S, de Reyniès, A, Laenen, A, Baldewijns, M, Beuselinck, B.

Circulating Levels of the Interferon-γ-Regulated Chemokines CXCL10/CXCL11, IL-6 and HGF Predict Outcome in Metastatic Renal Cell Carcinoma Patients Treated with Antiangiogenic Therapy.

Esteban, E, Exposito, F, Crespo, G, Lambea, J, Pinto, A, Puente, J, Arranz, JA, Redrado, M, Rodriguez-Antona, C , de Andrea, C, Lopez-Brea, M, Redin, E, Rodriguez, A, Serrano, D, Garcia, J, Grande, E, Castellano, D, Calvo, A.

MicroRNAs Possibly Involved in the Development of Bone Metastasis in Clear-Cell Renal Cell Carcinoma.

Kinget, L, Roussel, E, Lambrechts, D, Boeckx, B, Vanginderhuysen, L, Albersen, M, Rodríguez-Antona, C , Graña-Castro, O, Inglada-Pérez, L, Verbiest, A, Zucman-Rossi, J, Couchy, G, Caruso, S, Laenen, A, Baldewijns, M, Beuselinck, B.

Molecular characterization of chromophobe renal cell carcinoma reveals mTOR pathway alterations in patients with poor outcome.

Roldan-Romero, JM, Santos, M, Lanillos, J, Caleiras, E, Anguera, G, Maroto, P, García-Donas, J, de Velasco, G, Martinez-Montes, ÁM, Calsina, B, Monteagudo, M, Letón, R, Leandro-García, LJ, Montero-Conde, C , Cascón, A, Robledo, M, Rodriguez-Antona, C .

Overexpression of miR-483-5p is confined to metastases and linked to high circulating levels in patients with metastatic pheochromocytoma/paraganglioma.

Castro-Vega, LJ, Calsina, B, Burnichon, N, Drossart, T, Martínez-Montes, ÁM, Verkarre, V, Amar, L, Bertherat, J, Rodríguez-Antona, C , Favier, J, Robledo, M, Gimenez-Roqueplo, AP.

The need of the clinical implementation of pharmacogenetics in European health services for routine drug prescription. What's next? An urgent clinical unmet need for patients.

Taron, M, Llerena, A, Manolopoulos, VG, Rodriguez-Antona, C , Stankovic, S, van Schaik, RHN.

The need of the clinical implementation of pharmacogenetics in European health services for routine drug prescription. What's next? An urgent clinical unmet need for patients.

Taron, M, Llerena, A, Manolopoulos, VG, Rodriguez-Antona, C , Stankovic, S, van Schaik, RHN.

Novel DNMT3A Germline Variant in a Patient with Multiple Paragangliomas and Papillary Thyroid Carcinoma.

Mellid, S, Coloma, J, Calsina, B, Monteagudo, M, Roldán-Romero, JM, Santos, M, Leandro-García, LJ, Lanillos, J, Martínez-Montes, ÁM, Rodríguez-Antona, C , Montero-Conde, C , Martínez-López, J, Ayala, R, Matias-Guiu, X, Robledo, M, Cascón, A.

CD133 Expression in Medullary Thyroid Cancer Cells Identifies Patients with Poor Prognosis.

Cordero-Barreal, A , Caleiras, E, López de Maturana, E, Monteagudo, M, Martínez-Montes, ÁM, Letón, R, Gil, E, Álvarez-Escolá, C, Regojo, RM, Andía, V, Marazuela, M, Guadalix, S, Calatayud, M, Robles-Díaz, L, Aguirre, M, Cano, JM, Díaz, JÁ, Saavedra, P, Lamas, C, Azriel, S, Sastre, J, Aller, J, Leandro-García, LJ, Calsina, B, Roldán-Romero, JM, Santos, M, Lanillos, J, Cascón, A, Rodríguez-Antona, C , Robledo, M, Montero-Conde, C .

Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE).

Talhouk, A, George, J, Wang, C, Budden, T, Tan, TZ, Chiu, DS, Kommoss, S, Leong, HS, Chen, S, Intermaggio, MP, Gilks, B, Nazeran, TM, Volchek, M, Elatre, W, Bentley, RC, Senz, J, Lum, A, Chow, V, Sudderuddin, H, Mackenzie, R, Leong, SCY, Liu, G, Johnson, D, Chen, B, Group, A, Alsop, J, Banerjee, SN, Behrens, S, Bodelon, C, Brand, AH, Brinton, L, Carney, ME, Chiew, YE, Cushing-Haugen, KL, Cybulski, C, Ennis, D, Fereday, S, Fortner, RT, García-Donas, J, Gentry-Maharaj, A, Glasspool, R, Goranova, T, Greene, CS, Haluska, P, Harris, HR, Hendley, J, Hernandez, BY, Herpel, E, Jimenez-Linan, M, Karpinskyj, C, Kaufmann, SH, Keeney, GL, Kennedy, CJ, Köbel, M, Koziak, JM, Larson, MC, Lester, J, Lewsley, LA, Lissowska, J, Lubiński, J, Luk, H, Macintyre, G, Mahner, S, McNeish, IA, Menkiszak, J, Nevins, N, Osorio, A, Oszurek, O, Palacios, J, Hinsley, S, Pearce, CL, Pike, MC, Piskorz, AM, Ray-Coquard, I, Rhenius, V, Rodriguez-Antona, C , Sharma, R, Sherman, ME, De Silva, D, Singh, N, Sinn, P, Slamon, D, Song, H, Steed, H, Stronach, EA, Thompson, PJ, Tołoczko, A, Trabert, B, Traficante, N, Tseng, CC, Widschwendter, M, Wilkens, LR, Winham, SJ, Winterhoff, B, Beeghly-Fadiel, A, Benitez, J, Berchuck, A, Brenton, JD, Brown, R, Chang-Claude, J, Chenevix-Trench, G, deFazio, A, Fasching, PA, García, MJ, Gayther, SA, Goodman, MT, Gronwald, J, Henderson, MJ, Karlan, BY, Kelemen, LE, Menon, U, Orsulic, S, Pharoah, PDP, Wentzensen, N, Wu, AH, Schildkraut, JM, Rossing, MA, Konecny, GE, Huntsman, DG, Huang, RY, Goode, EL, Ramus, SJ, Doherty, JA, Bowtell, DD, Anglesio, MS.

MicroRNA expression profiles in molecular subtypes of clear-cell renal cell carcinoma are associated with clinical outcome and repression of specific mRNA targets.

Verbiest, A, Van Hoef, V, Rodriguez-Antona, C , García-Donas, J, Graña-Castro, O, Albersen, M, Baldewijns, M, Laenen, A, Roussel, E, Schöffski, P, Wozniak, A, Caruso, S, Couchy, G, Zucman-Rossi, J, Beuselinck, B.

Clinical and pathological associations of PTEN expression in ovarian cancer: a multicentre study from the Ovarian Tumour Tissue Analysis Consortium.

Martins, FC, Couturier, DL, Paterson, A, Karnezis, AN, Chow, C, Nazeran, TM, Odunsi, A, Gentry-Maharaj, A, Vrvilo, A, Hein, A, Talhouk, A, Osorio, A, Hartkopf, AD, Brooks-Wilson, A, DeFazio, A, Fischer, A, Hartmann, A, Hernandez, BY, McCauley, BM, Karpinskyj, C, de Sousa, CB, Høgdall, C, Tiezzi, DG, Herpel, E, Taran, FA, Modugno, F, Keeney, G, Nelson, G, Steed, H, Song, H, Luk, H, Benitez, J, Alsop, J, Koziak, JM, Lester, J, Rothstein, JH, de Andrade, JM, Lundvall, L, Paz-Ares, L, Robles-Díaz, L, Wilkens, LR, Garcia, MJ, Intermaggio, MP, Alcaraz, ML, Brett, MA, Beckmann, MW, Jimenez-Linan, M, Anglesio, M, Carney, ME, Schneider, M, Traficante, N, Pejovic, N, Singh, N, Le, N, Sinn, P, Ghatage, P, Erber, R, Edwards, R, Vierkant, R, Ness, RB, Leung, S, Orsulic, S, Brucker, SY, Kaufmann, SH, Fereday, S, Gayther, S, Winham, SJ, Kommoss, S, Pejovic, T, Longacre, TA, McGuire, V, Rhenius, V, Sieh, W, Shvetsov, YB, Whittemore, AS, Staebler, A, Karlan, BY, Rodriguez-Antona, C , Bowtell, DD, Goode, EL, Høgdall, E, Candido Dos Reis, FJ, Gronwald, J, Chang-Claude, J, Moysich, KB, Kelemen, LE, Cook, LS, Goodman, MT, Fasching, PA, Crawford, R, Deen, S, Menon, U, Huntsman, DG, Köbel, M, Ramus, SJ, Pharoah, PDP, Brenton, JD.

Genetic association of gemcitabine/carboplatin-induced leukopenia and neutropenia in non-small cell lung cancer patients using whole-exome sequencing.

Svedberg, A, Björn, N, Sigurgeirsson, B, Pradhananga, S, Brandén, E, Koyi, H, Lewensohn, R, De Petris, L, Apellániz-Ruiz, M, Rodríguez-Antona, C , Lundeberg, J, Gréen, H.

P-Glycoprotein Inhibition Exacerbates Paclitaxel Neurotoxicity in Neurons and Patients With Cancer.

Stage, TB, Mortensen, C, Khalaf, S, Steffensen, V, Hammer, HS, Xiong, C, Nielsen, F, Poetz, O, Svenningsen, ÅF, Rodriguez-Antona, C , Kroetz, DL.

A Novel Approach for the Identification of Pharmacogenetic Variants in MT-RNR1 through Next-Generation Sequencing Off-Target Data.

Lanillos, J, Santos, M, Carcajona, M, Roldan-Romero, JM, Martinez, AM, Calsina, B, Monteagudo, M, Leandro-García, LJ, Montero-Conde, C , Cascón, A, Maietta, P, Alvarez, S, Robledo, M, Rodriguez-Antona, C .

Effect of the Most Relevant CYP3A4 and CYP3A5 Polymorphisms on the Pharmacokinetic Parameters of 10 CYP3A Substrates.

Saiz-Rodríguez, M, Almenara, S, Navares-Gómez, M, Ochoa, D, Román, M, Zubiaur, P, Koller, D, Santos, M, Mejía, G, Borobia, AM, Rodríguez-Antona, C , Abad-Santos, F.

Genes and variants in hematopoiesis-related pathways are associated with gemcitabine/carboplatin-induced thrombocytopenia.

Björn, N, Sigurgeirsson, B, Svedberg, A, Pradhananga, S, Brandén, E, Koyi, H, Lewensohn, R, de Petris, L, Apellániz-Ruiz, M, Rodríguez-Antona, C , Lundeberg, J, Gréen, H.

PTEN expression and mutations in TSC1, TSC2 and MTOR are associated with response to rapalogs in patients with renal cell carcinoma.

Roldan-Romero, JM, Beuselinck, B, Santos, M, Rodriguez-Moreno, JF, Lanillos, J, Calsina, B, Gutierrez, A, Tang, K, Lainez, N, Puente, J, Castellano, D, Esteban, E, Climent, MA, Arranz, JA, Albersen, M, Oudard, S, Couchy, G, Caleiras, E, Montero-Conde, C , Cascón, A, Robledo, M, Rodríguez-Antona, C , García-Donas, J, , .

Hsa-miR-139-5p is a prognostic thyroid cancer marker involved in HNRNPF-mediated alternative splicing.

Montero-Conde, C , Graña-Castro, O, Martín-Serrano, G, Martínez-Montes, ÁM, Zarzuela, E, Muñoz, J, Torres-Perez, R, Pita, G, Cordero-Barreal, A , Leandro-García, LJ, Letón, R, López de Silanes, I, Guadalix, S, Pérez-Barrios, A, Hawkins, F, Guerrero-Álvarez, A, Álvarez-Escolá, C, Regojo-Zapata, RM, Calsina, B, Remacha, L, Roldán-Romero, JM, Santos, M, Lanillos, J, Jordá, M, Riesco-Eizaguirre, G , Zafon, C, González-Neira, A, Blasco, MA, Al-Shahrour, F, Rodríguez-Antona, C , Cascón, A, Robledo, M.

A Pilot, Phase II, Randomized, Open-Label Clinical Trial Comparing the Neurotoxicity of Three Dose Regimens of Nab-Paclitaxel to That of Solvent-Based Paclitaxel as the First-Line Treatment for Patients with Human Epidermal Growth Factor Receptor Type 2-Negative Metastatic Breast Cancer.

Ciruelos, E, Apellániz-Ruiz, M, Cantos, B, Martinez-Jáñez, N, Bueno-Muiño, C, Echarri, MJ, Enrech, S, Guerra, JA, Manso, L, Pascual, T, Dominguez, C, Gonzalo, JF, Sanz, JL, Rodriguez-Antona, C , Sepúlveda, JM.

Concomitant Medications and Risk of Chemotherapy-Induced Peripheral Neuropathy.

Sánchez-Barroso, L, Apellaniz-Ruiz, M, Gutiérrez-Gutiérrez, G, Santos, M, Roldán-Romero, JM, Curras, M, Remacha, L, Calsina, B, Calvo, I, Sereno, M, Merino, M, García-Donas, J, Castelo, B, Guerra, E, Letón, R, Montero-Conde, C , Cascón, A, Inglada-Pérez, L, Robledo, M, Rodríguez-Antona, C .

Integrative multi-omics analysis identifies a prognostic miRNA signature and a targetable miR-21-3p/TSC2/mTOR axis in metastatic pheochromocytoma/paraganglioma.

Calsina, B, Castro-Vega, LJ, Torres-Pérez, R, Inglada-Pérez, L, Currás-Freixes, M, Roldán-Romero, JM, Mancikova, V, Letón, R, Remacha, L, Santos, M, Burnichon, N, Lussey-Lepoutre, C, Rapizzi, E, Graña, O, Álvarez-Escolá, C, de Cubas, AA, Lanillos, J, Cordero-Barreal, A , Martínez-Montes, ÁM, Bellucci, A, Amar, L, Fernandes-Rosa, FL, Calatayud, M, Aller, J, Lamas, C, Sastre-Marcos, J, Canu, L, Korpershoek, E, Timmers, HJ, Lenders, JW, Beuschlein, F, Fassnacht-Capeller, M, Eisenhofer, G, Mannelli, M, Al-Shahrour, F, Favier, J, Rodríguez-Antona, C , Cascón, A, Montero-Conde, C , Gimenez-Roqueplo, AP, Robledo, M.

Recurrent Germline DLST Mutations in Individuals with Multiple Pheochromocytomas and Paragangliomas.

Remacha, L, Pirman, D, Mahoney, CE, Coloma, J, Calsina, B, Currás-Freixes, M, Letón, R, Torres-Pérez, R, Richter, S, Pita, G, Herráez, B, Cianchetta, G, Honrado, E, Maestre, L, Urioste, M, Aller, J, García-Uriarte, Ó, Gálvez, MÁ, Luque, RM, Lahera, M, Moreno-Rengel, C, Eisenhofer, G, Montero-Conde, C , Rodríguez-Antona, C , Llorca, Ó, Smolen, GA, Robledo, M, Cascón, A.

Recurrent Germline DLST Mutations in Individuals with Multiple Pheochromocytomas and Paragangliomas.

Remacha, L, Pirman, D, Mahoney, CE, Coloma, J, Calsina, B, Currás-Freixes, M, Letón, R, Torres-Pérez, R, Richter, S, Pita, G, Herráez, B, Cianchetta, G, Honrado, E, Maestre, L, Urioste, M, Aller, J, García-Uriarte, Ó, Gálvez, MÁ, Luque, RM, Lahera, M, Moreno-Rengel, C, Eisenhofer, G, Montero-Conde, C , Rodríguez-Antona, C , Llorca, Ó, Smolen, GA, Robledo, M, Cascón, A.

Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk.

Yang, Y, Wu, L, Shu, X, Lu, Y, Shu, XO, Cai, Q, Beeghly-Fadiel, A, Li, B, Ye, F, Berchuck, A, Anton-Culver, H, Banerjee, S, Benitez, J, Bjørge, L, Brenton, JD, Butzow, R, Campbell, IG, Chang-Claude, J, Chen, K, Cook, LS, Cramer, DW, deFazio, A, Dennis, J, Doherty, JA, Dörk, T, Eccles, DM, Edwards, DV, Fasching, PA, Fortner, RT, Gayther, SA, Giles, GG, Glasspool, RM, Goode, EL, Goodman, MT, Gronwald, J, Harris, HR, Heitz, F, Hildebrandt, MA, Høgdall, E, Høgdall, CK, Huntsman, DG, Kar, SP, Karlan, BY, Kelemen, LE, Kiemeney, LA, Kjaer, SK, Koushik, A, Lambrechts, D, Le, ND, Levine, DA, Massuger, LF, Matsuo, K, May, T, McNeish, IA, Menon, U, Modugno, F, Monteiro, AN, Moorman, PG, Moysich, KB, Ness, RB, Nevanlinna, H, Olsson, H, Onland-Moret, NC, Park, SK, Paul, J, Pearce, CL, Pejovic, T, Phelan, CM, Pike, MC, Ramus, SJ, Riboli, E, Rodriguez-Antona, C , Romieu, I, Sandler, DP, Schildkraut, JM, Setiawan, VW, Shan, K, Siddiqui, N, Sieh, W, Stampfer, MJ, Sutphen, R, Swerdlow, AJ, Szafron, LM, Teo, SH, Tworoger, SS, Tyrer, JP, Webb, PM, Wentzensen, N, White, E, Willett, WC, Wolk, A, Woo, YL, Wu, AH, Yan, L, Yannoukakos, D, Chenevix-Trench, G, Sellers, TA, Pharoah, PDP, Zheng, W, Long, J.

Gain-of-function mutations in DNMT3A in patients with paraganglioma.

Remacha, L, Currás-Freixes, M, Torres-Ruiz, R, Schiavi, F, Torres-Pérez, R, Calsina, B, Letón, R, Comino-Méndez, I, Roldán-Romero, JM, Montero-Conde, C , Santos, M, Pérez, LI, Pita, G, Alonso, MR, Honrado, E, Pedrinaci, S, Crespo-Facorro, B, Percesepe, A, Falcioni, M, Rodríguez-Perales, S, Korpershoek, E, Ramón-Maiques, S, Opocher, G, Rodríguez-Antona, C , Robledo, M, Cascón, A.

Role of MDH2 pathogenic variant in pheochromocytoma and paraganglioma patients.

Calsina, B, Currás-Freixes, M, Buffet, A, Pons, T, Contreras, L, Letón, R, Comino-Méndez, I, Remacha, L, Calatayud, M, Obispo, B, Martin, A, Cohen, R, Richter, S, Balmaña, J, Korpershoek, E, Rapizzi, E, Deutschbein, T, Vroonen, L, Favier, J, de Krijger, RR, Fassnacht, M, Beuschlein, F, Timmers, HJ, Eisenhofer, G, Mannelli, M, Pacak, K, Satrústegui, J, Rodríguez-Antona, C , Amar, L, Cascón, A, Dölker, N, Gimenez-Roqueplo, AP, Robledo, M.

Prognostic and predictive biomarkers for somatostatin analogs, peptide receptor radionuclide therapy and serotonin pathway targets in neuroendocrine tumours.

Barriuso, J, Custodio, A, Afonso, R, Alonso, V, Astudillo, A, Capdevila, J, García-Carbonero, R, Grande, E, Jimenez-Fonseca, P, Marazuela, M, Rodríguez-Antona, C , Aller, J.

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk.

Lu, Y, Beeghly-Fadiel, A, Wu, L, Guo, X, Li, B, Schildkraut, JM, Im, HK, Chen, YA, Permuth, JB, Reid, BM, Teer, JK, Moysich, KB, Andrulis, IL, Anton-Culver, H, Arun, BK, Bandera, EV, Barkardottir, RB, Barnes, DR, Benitez, J, Bjorge, L, Brenton, J, Butzow, R, Caldes, T, Caligo, MA, Campbell, I, Chang-Claude, J, Claes, KBM, Couch, FJ, Cramer, DW, Daly, MB, deFazio, A, Dennis, J, Diez, O, Domchek, SM, Dörk, T, Easton, DF, Eccles, DM, Fasching, PA, Fortner, RT, Fountzilas, G, Friedman, E, Ganz, PA, Garber, J, Giles, GG, Godwin, AK, Goldgar, DE, Goodman, MT, Greene, MH, Gronwald, J, Hamann, U, Heitz, F, Hildebrandt, MAT, Høgdall, CK, Hollestelle, A, Hulick, PJ, Huntsman, DG, Imyanitov, EN, Isaacs, C, Jakubowska, A, James, P, Karlan, BY, Kelemen, LE, Kiemeney, LA, Kjaer, SK, Kwong, A, Le, ND, Leslie, G, Lesueur, F, Levine, DA, Mattiello, A, May, T, McGuffog, L, McNeish, IA, Merritt, MA, Modugno, F, Montagna, M, Neuhausen, SL, Nevanlinna, H, Nielsen, FC, Nikitina-Zake, L, Nussbaum, RL, Offit, K, Olah, E, Olopade, OI, Olson, SH, Olsson, H, Osorio, A, Park, SK, Parsons, MT, Peeters, PHM, Pejovic, T, Peterlongo, P, Phelan, CM, Pujana, MA, Ramus, SJ, Rennert, G, Risch, H, Rodriguez, GC, Rodríguez-Antona, C , Romieu, I, Rookus, MA, Rossing, MA, Rzepecka, IK, Sandler, DP, Schmutzler, RK, Setiawan, VW, Sharma, P, Sieh, W, Simard, J, Singer, CF, Song, H, Southey, MC, Spurdle, AB, Sutphen, R, Swerdlow, AJ, Teixeira, MR, Teo, SH, Thomassen, M, Tischkowitz, M, Toland, AE, Trichopoulou, A, Tung, N, Tworoger, SS, van Rensburg, EJ, Vanderstichele, A, Vega, A, Edwards, DV, Webb, PM, Weitzel, JN, Wentzensen, N, White, E, Wolk, A, Wu, AH, Yannoukakos, D, Zorn, KK, Gayther, SA, Antoniou, AC, Berchuck, A, Goode, EL, Chenevix-Trench, G, Sellers, TA, Pharoah, PDP, Zheng, W, Long, J.

A Genetic Polymorphism in CTLA-4 Is Associated with Overall Survival in Sunitinib-Treated Patients with Clear Cell Metastatic Renal Cell Carcinoma.

Liu, X, Swen, JJ, Diekstra, MHM, Boven, E, Castellano, D, Gelderblom, H, Mathijssen, RHJ, Vermeulen, SH, Oosterwijk, E, Junker, K, Roessler, M, Alexiusdottir, K, Sverrisdottir, A, Radu, MT, Ambert, V, Eisen, T, Warren, A, Rodríguez-Antona, C , García-Donas, J, Böhringer, S, Koudijs, KKM, Kiemeney, LALM, Rini, BI, Guchelaar, HJ.

Advanced sporadic renal epithelioid angiomyolipoma: case report of an extraordinary response to sirolimus linked to TSC2 mutation.

Espinosa, M, Roldán-Romero, JM, Duran, I, de Álava, E, Apellaniz-Ruiz, M, Cascón, A, Garrigos, C, Robledo, M, Rodriguez-Antona, C .

Association between SLC19A1 Gene Polymorphism and High Dose Methotrexate Toxicity in Childhood Acute Lymphoblastic Leukaemia and Non Hodgkin Malignant Lymphoma: Introducing a Haplotype based Approach.

Kotnik, BF, Jazbec, J, Grabar, PB, Rodriguez-Antona, C , Dolzan, V.

A Prospective Observational Study for Assessment and Outcome Association of Circulating Endothelial Cells in Clear Cell Renal Cell Carcinoma Patients Who Show Initial Benefit from First-line Treatment. The CIRCLES (CIRCuLating Endothelial cellS) Study (SOGUG-CEC-2011-01).

García-Donas, J, Leon, LA, Esteban, E, Vidal-Mendez, MJ, Arranz, JA, Garcia Del Muro, X, Basterretxea, L, González Del Alba, A, Climent, MA, Virizuela, JA, Álvarez, C, Sepúlveda, J, Anido, U, López, C, Ortiz-Morales, MJ, Pérez, X, Rodriguez-Antona, C , Rodriguez-Moreno, JF, Hernando, S, Castellano, D.

Description of the EuroTARGET cohort: A European collaborative project on TArgeted therapy in renal cell cancer-GEnetic- and tumor-related biomarkers for response and toxicity.

van der Zanden, LFM, Vermeulen, SH, Oskarsdottir, A, Maurits, JSF, Diekstra, MHM, Ambert, V, Cambon-Thomsen, A, Castellano, D, Fritsch, A, Garcia Donas, J, Guarch Troyas, R, Guchelaar, HJ, Hartmann, A, Hulsbergen-van de Kaa, C, Jaehde, U, Junker, K, Martinez-Cardus, A, Masson, G, Oosterwijk-Wakka, J, Radu, MT, Rafnar, T, Rodriguez-Antona, C , Roessler, M, Ruijtenbeek, R, Stefansson, K, Warren, A, Wessels, L, Eisen, T, Kiemeney, LALM, Oosterwijk, E.

Polymorphisms associated with everolimus pharmacokinetics, toxicity and survival in metastatic breast cancer.

Pascual, T, Apellániz-Ruiz, M, Pernaut, C, Cueto-Felgueroso, C, Villalba, P, Álvarez, C, Manso, L, Inglada-Pérez, L, Robledo, M, Rodríguez-Antona, C , Ciruelos, E.

PheoSeq: A Targeted Next-Generation Sequencing Assay for Pheochromocytoma and Paraganglioma Diagnostics.

Currás-Freixes, M, Piñeiro-Yañez, E, Montero-Conde, C , Apellániz-Ruiz, M, Calsina, B, Mancikova, V, Remacha, L, Richter, S, Ercolino, T, Rogowski-Lehmann, N, Deutschbein, T, Calatayud, M, Guadalix, S, Álvarez-Escolá, C, Lamas, C, Aller, J, Sastre-Marcos, J, Lázaro, C, Galofré, JC, Patiño-García, A, Meoro-Avilés, A, Balmaña-Gelpi, J, De Miguel-Novoa, P, Balbín, M, Matías-Guiu, X, Letón, R, Inglada-Pérez, L, Torres-Pérez, R, Roldán-Romero, JM, Rodríguez-Antona, C , Fliedner, SMJ, Opocher, G, Pacak, K, Korpershoek, E, de Krijger, RR, Vroonen, L, Mannelli, M, Fassnacht, M, Beuschlein, F, Eisenhofer, G, Cascón, A, Al-Shahrour, F, Robledo, M.

Evaluation of KDR rs34231037 as a predictor of sunitinib efficacy in patients with metastatic renal cell carcinoma.

Apellániz-Ruiz, M, Diekstra, MH, Roldán, JM, Boven, E, Castellano, D, Gelderblom, H, Mathijssen, RHJ, Swen, JJ, Böhringer, S, García-Donás, J, Rini, BI, Guchelaar, HJ, Rodríguez-Antona, C .

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

Phelan, CM, Kuchenbaecker, KB, Tyrer, JP, Kar, SP, Lawrenson, K, Winham, SJ, Dennis, J, Pirie, A, Riggan, MJ, Chornokur, G, Earp, MA, Lyra, PC, Lee, JM, Coetzee, S, Beesley, J, McGuffog, L, Soucy, P, Dicks, E, Lee, A, Barrowdale, D, Lecarpentier, J, Leslie, G, Aalfs, CM, Aben, KKH, Adams, M, Adlard, J, Andrulis, IL, Anton-Culver, H, Antonenkova, N, , , Aravantinos, G, Arnold, N, Arun, BK, Arver, B, Azzollini, J, Balmaña, J, Banerjee, SN, Barjhoux, L, Barkardottir, RB, Bean, Y, Beckmann, MW, Beeghly-Fadiel, A, Benitez, J, Bermisheva, M, Bernardini, MQ, Birrer, MJ, Bjorge, L, Black, A, Blankstein, K, Blok, MJ, Bodelon, C, Bogdanova, N, Bojesen, A, Bonanni, B, Borg, Å, Bradbury, AR, Brenton, JD, Brewer, C, Brinton, L, Broberg, P, Brooks-Wilson, A, Bruinsma, F, Brunet, J, Buecher, B, Butzow, R, Buys, SS, Caldes, T, Caligo, MA, Campbell, I, Cannioto, R, Carney, ME, Cescon, T, Chan, SB, Chang-Claude, J, Chanock, S, Chen, XQ, Chiew, YE, Chiquette, J, Chung, WK, Claes, KBM, Conner, T, Cook, LS, Cook, J, Cramer, DW, Cunningham, JM, D'Aloisio, AA, Daly, MB, Damiola, F, Damirovna, SD, Dansonka-Mieszkowska, A, Dao, F, Davidson, R, DeFazio, A, Delnatte, C, Doheny, KF, Diez, O, Ding, YC, Doherty, JA, Domchek, SM, Dorfling, CM, Dörk, T, Dossus, L, Duran, M, Dürst, M, Dworniczak, B, Eccles, D, Edwards, T, Eeles, R, Eilber, U, Ejlertsen, B, Ekici, AB, Ellis, S, Elvira, M, , , Eng, KH, Engel, C, Evans, DG, Fasching, PA, Ferguson, S, Ferrer, SF, Flanagan, JM, Fogarty, ZC, Fortner, RT, Fostira, F, Foulkes, WD, Fountzilas, G, Fridley, BL, Friebel, TM, Friedman, E, Frost, D, Ganz, PA, Garber, J, García, MJ, Garcia-Barberan, V, Gehrig, A, , , Gentry-Maharaj, A, Gerdes, AM, Giles, GG, Glasspool, R, Glendon, G, Godwin, AK, Goldgar, DE, Goranova, T, Gore, M, Greene, MH, Gronwald, J, Gruber, S, Hahnen, E, Haiman, CA, Håkansson, N, Hamann, U, Hansen, TVO, Harrington, PA, Harris, HR, Hauke, J, , , Hein, A, Henderson, A, Hildebrandt, MAT, Hillemanns, P, Hodgson, S, Høgdall, CK, Høgdall, E, Hogervorst, FBL, Holland, H, Hooning, MJ, Hosking, K, Huang, RY, Hulick, PJ, Hung, J, Hunter, DJ, Huntsman, DG, Huzarski, T, Imyanitov, EN, Isaacs, C, Iversen, ES, Izatt, L, Izquierdo, A, Jakubowska, A, James, P, Janavicius, R, Jernetz, M, Jensen, A, Jensen, UB, John, EM, Johnatty, S, Jones, ME, Kannisto, P, Karlan, BY, Karnezis, A, Kast, K, , , Kennedy, CJ, Khusnutdinova, E, Kiemeney, LA, Kiiski, JI, Kim, SW, Kjaer, SK, Köbel, M, Kopperud, RK, Kruse, TA, Kupryjanczyk, J, Kwong, A, Laitman, Y, Lambrechts, D, Larrañaga, N, Larson, MC, Lazaro, C, Le, ND, Le Marchand, L, Lee, JW, Lele, SB, Leminen, A, Leroux, D, Lester, J, Lesueur, F, Levine, DA, Liang, D, Liebrich, C, Lilyquist, J, Lipworth, L, Lissowska, J, Lu, KH, Lubinński, J, Luccarini, C, Lundvall, L, Mai, PL, Mendoza-Fandiño, G, Manoukian, S, Massuger, LFAG, May, T, Mazoyer, S, McAlpine, JN, McGuire, V, McLaughlin, JR, McNeish, I, Meijers-Heijboer, H, Meindl, A, Menon, U, Mensenkamp, AR, Merritt, MA, Milne, RL, Mitchell, G, Modugno, F, Moes-Sosnowska, J, Moffitt, M, Montagna, M, Moysich, KB, Mulligan, AM, Musinsky, J, Nathanson, KL, Nedergaard, L, Ness, RB, Neuhausen, SL, Nevanlinna, H, Niederacher, D, Nussbaum, RL, Odunsi, K, Olah, E, Olopade, OI, Olsson, H, Olswold, C, O'Malley, DM, Ong, KR, Onland-Moret, NC, , , Orr, N, Orsulic, S, Osorio, A, Palli, D, Papi, L, Park-Simon, TW, Paul, J, Pearce, CL, Pedersen, IS, Peeters, PHM, Peissel, B, Peixoto, A, Pejovic, T, Pelttari, LM, Permuth, JB, Peterlongo, P, Pezzani, L, Pfeiler, G, Phillips, KA, Piedmonte, M, Pike, MC, Piskorz, AM, Poblete, SR, Pocza, T, Poole, EM, Poppe, B, Porteous, ME, Prieur, F, Prokofyeva, D, Pugh, E, Pujana, MA, Pujol, P, Radice, P, Rantala, J, Rappaport-Fuerhauser, C, Rennert, G, Rhiem, K, Rice, P, Richardson, A, Robson, M, Rodriguez, GC, Rodríguez-Antona, C , Romm, J, Rookus, MA, Rossing, MA, Rothstein, JH, Rudolph, A, Runnebaum, IB, Salvesen, HB, Sandler, DP, Schoemaker, MJ, Senter, L, Setiawan, VW, Severi, G, Sharma, P, Shelford, T, Siddiqui, N, Side, LE, Sieh, W, Singer, CF, Sobol, H, Song, H, Southey, MC, Spurdle, AB, Stadler, Z, Steinemann, D, Stoppa-Lyonnet, D, Sucheston-Campbell, LE, Sukiennicki, G, Sutphen, R, Sutter, C, Swerdlow, AJ, Szabo, CI, Szafron, L, Tan, YY, Taylor, JA, Tea, MK, Teixeira, MR, Teo, SH, Terry, KL, Thompson, PJ, Thomsen, LCV, Thull, DL, Tihomirova, L, Tinker, AV, Tischkowitz, M, Tognazzo, S, Toland, AE, Tone, A, Trabert, B, Travis, RC, Trichopoulou, A, Tung, N, Tworoger, SS, van Altena, AM, Van Den Berg, D, van der Hout, AH, van der Luijt, RB, Van Heetvelde, M, Van Nieuwenhuysen, E, van Rensburg, EJ, Vanderstichele, A, Varon-Mateeva, R, Vega, A, Edwards, DV, Vergote, I, Vierkant, RA, Vijai, J, Vratimos, A, Walker, L, Walsh, C, Wand, D, Wang-Gohrke, S, Wappenschmidt, B, Webb, PM, Weinberg, CR, Weitzel, JN, Wentzensen, N, Whittemore, AS, Wijnen, JT, Wilkens, LR, Wolk, A, Woo, M, Wu, X, Wu, AH, Yang, H, Yannoukakos, D, Ziogas, A, Zorn, KK, Narod, SA, Easton, DF, Amos, CI, Schildkraut, JM, Ramus, SJ, Ottini, L, Goodman, MT, Park, SK, Kelemen, LE, Risch, HA, Thomassen, M, Offit, K, Simard, J, Schmutzler, RK, Hazelett, D, Monteiro, AN, Couch, FJ, Berchuck, A, Chenevix-Trench, G, Goode, EL, Sellers, TA, Gayther, SA, Antoniou, AC, Pharoah, PDP.

Targeted Sequencing Reveals Low-Frequency Variants in EPHA Genes as Markers of Paclitaxel-Induced Peripheral Neuropathy.

Apellániz-Ruiz, M, Tejero, H, Inglada-Pérez, L, Sánchez-Barroso, L, Gutiérrez-Gutiérrez, G, Calvo, I, Castelo, B, Redondo, A, García-Donás, J, Romero-Laorden, N, Sereno, M, Merino, M, Currás-Freixes, M, Montero-Conde, C , Mancikova, V, Åvall-Lundqvist, E, Green, H, Al-Shahrour, F, Cascón, A, Robledo, M, Rodríguez-Antona, C .

Meta-analysis on the association of VEGFR1 genetic variants with sunitinib outcome in metastatic renal cell carcinoma patients.

Liu, X, Swen, JJ, Boven, E, Castellano, D, Gelderblom, H, Mathijssen, RH, Rodríguez-Antona, C , García-Donas, J, Rini, BI, Guchelaar, HJ.

Sunitinib-induced hypertension in CYP3A4 rs4646437 A-allele carriers with metastatic renal cell carcinoma.

Diekstra, MH, Belaustegui, A, Swen, JJ, Boven, E, Castellano, D, Gelderblom, H, Mathijssen, RH, García-Donas, J, Rodríguez-Antona, C , Rini, BI, Guchelaar, HJ.

Deep sequencing reveals microRNAs predictive of antiangiogenic drug response.

García-Donas, J, Beuselinck, B, Inglada-Pérez, L, Graña, O, Schöffski, P, Wozniak, A, Bechter, O, Apellániz-Ruiz, M, Leandro-García, LJ, Esteban, E, Castellano, DE, González Del Alba, A, Climent, MA, Hernando, S, Arranz, JA, Morente, M, Pisano, DG, Robledo, M, Rodriguez-Antona, C .

SNPs associated with activity and toxicity of cabazitaxel in patients with advanced urothelial cell carcinoma.

Duran, I, Hagen, C, Arranz, JÁ, Apellaniz-Ruiz, M, Pérez-Valderrama, B, Sala, N, Lainez, N, García-Del Muro, X, Noguerón, E, Climent, MÁ, Maroto, P, Font, A, García-Donas, J, Gallardo, E, López-Criado, P, González Del Alba, A, Sáez, MI, Vázquez, S, Luque, R, Rodríguez-Antona, C .

The role of pharmacogenetics and pharmacogenomics in 21st-century medicine: state of the art and new challenges discussed in the VII Conference of the Spanish Pharmacogenetics and Pharmacogenomics Society (SEFF).

Rodriguez-Antona, C .

Association of single nucleotide polymorphisms in IL8 and IL13 with sunitinib-induced toxicity in patients with metastatic renal cell carcinoma.

Diekstra, MH, Liu, X, Swen, JJ, Boven, E, Castellano, D, Gelderblom, H, Mathijssen, RH, Rodríguez-Antona, C , García-Donas, J, Rini, BI, Guchelaar, HJ.

Functional and in silico assessment of MAX variants of unknown significance.

Comino-Méndez, I, Leandro-García, LJ, Montoya, G, Inglada-Pérez, L, de Cubas, AA, Currás-Freixes, M, Tysoe, C, Izatt, L, Letón, R, Gómez-Graña, Á, Mancikova, V, Apellániz-Ruiz, M, Mannelli, M, Schiavi, F, Favier, J, Gimenez-Roqueplo, AP, Timmers, HJ, Roncador, G, Garcia, JF, Rodríguez-Antona, C , Robledo, M, Cascón, A.

Recommendations for somatic and germline genetic testing of single pheochromocytoma and paraganglioma based on findings from a series of 329 patients.

Currás-Freixes, M, Inglada-Pérez, L, Mancikova, V, Montero-Conde, C , Letón, R, Comino-Méndez, I, Apellániz-Ruiz, M, Sánchez-Barroso, L, Aguirre Sánchez-Covisa, M, Alcázar, V, Aller, J, Álvarez-Escolá, C, Andía-Melero, VM, Azriel-Mira, S, Calatayud-Gutiérrez, M, Díaz, JÁ, Díez-Hernández, A, Lamas-Oliveira, C, Marazuela, M, Matias-Guiu, X, Meoro-Avilés, A, Patiño-García, A, Pedrinaci, S, Riesco-Eizaguirre, G , Sábado-Álvarez, C, Sáez-Villaverde, R, Sainz de Los Terreros, A, Sanz Guadarrama, Ó, Sastre-Marcos, J, Scolá-Yurrita, B, Segura-Huerta, Á, Serrano-Corredor, Mde L, Villar-Vicente, MR, Rodríguez-Antona, C , Korpershoek, E, Cascón, A, Robledo, M.

Pazopanib in pretreated advanced neuroendocrine tumors: a phase II, open-label trial of the Spanish Task Force Group for Neuroendocrine Tumors (GETNE).

Grande, E, Capdevila, J, Castellano, D, Teulé, A, Durán, I, Fuster, J, Sevilla, I, Escudero, P, Sastre, J, García-Donas, J, Casanovas, O, Earl, J, Ortega, L, Apellaniz-Ruiz, M, Rodriguez-Antona, C , Alonso-Gordoa, T, Díez, JJ, Carrato, A, García-Carbonero, R.

DNA Methylation Profiling in Pheochromocytoma and Paraganglioma Reveals Diagnostic and Prognostic Markers.

de Cubas, AA, Korpershoek, E, Inglada-Pérez, L, Letouzé, E, Currás-Freixes, M, Fernández, AF, Comino-Méndez, I, Schiavi, F, Mancikova, V, Eisenhofer, G, Mannelli, M, Opocher, G, Timmers, H, Beuschlein, F, de Krijger, R, Cascon, A, Rodríguez-Antona, C , Fraga, MF, Favier, J, Gimenez-Roqueplo, AP, Robledo, M.

Replication of Genetic Polymorphisms Reported to Be Associated with Taxane-Related Sensory Neuropathy in Patients with Early Breast Cancer Treated with Paclitaxel--letter.

Apellániz-Ruiz, M, Sánchez-Barroso, L, Gutiérrez-Gutiérrez, G, Sereno, M, García-Donás, J, Åvall-Lundqvist, E, Gréen, H, Brøsen, K, Bergmann, TK, Rodríguez-Antona, C .

Role of cytochrome P450 2C8*3 (CYP2C8*3) in paclitaxel metabolism and paclitaxel-induced neurotoxicity.

Lee, MY, Apellániz-Ruiz, M, Johansson, I, Vikingsson, S, Bergmann, TK, Brøsen, K, Green, H, Rodríguez-Antona, C , Ingelman-Sundberg, M.

High frequency and founder effect of the CYP3A4*20 loss-of-function allele in the Spanish population classifies CYP3A4 as a polymorphic enzyme.

Apellániz-Ruiz, M, Inglada-Pérez, L, Naranjo, ME, Sánchez, L, Mancikova, V, Currás-Freixes, M, de Cubas, AA, Comino-Méndez, I, Triki, S, Rebai, A, Rasool, M, Moya, G, Grazina, M, Opocher, G, Cascón, A, Taboada-Echalar, P, Ingelman-Sundberg, M, Carracedo, A, Robledo, M, Llerena, A, Rodríguez-Antona, C .

IL8 polymorphisms and overall survival in pazopanib- or sunitinib-treated patients with renal cell carcinoma.

Xu, CF, Johnson, T, Garcia-Donas, J, Choueiri, TK, Sternberg, CN, Davis, ID, Bing, N, Deen, KC, Xue, Z, McCann, L, Esteban, E, Whittaker, JC, Spraggs, CF, Rodríguez-Antona, C , Pandite, LN, Motzer, RJ.

Whole-exome sequencing identifies MDH2 as a new familial paraganglioma gene.

Cascón, A, Comino-Méndez, I, Currás-Freixes, M, de Cubas, AA, Contreras, L, Richter, S, Peitzsch, M, Mancikova, V, Inglada-Pérez, L, Pérez-Barrios, A, Calatayud, M, Azriel, S, Villar-Vicente, R, Aller, J, Setién, F, Moran, S, Garcia, JF, Río-Machín, A, Letón, R, Gómez-Graña, Á, Apellániz-Ruiz, M, Roncador, G, Esteller, M, Rodríguez-Antona, C , Satrústegui, J, Eisenhofer, G, Urioste, M, Robledo, M.

Whole-exome sequencing reveals defective CYP3A4 variants predictive of paclitaxel dose-limiting neuropathy.

Apellániz-Ruiz, M, Lee, MY, Sánchez-Barroso, L, Gutiérrez-Gutiérrez, G, Calvo, I, García-Estévez, L, Sereno, M, García-Donás, J, Castelo, B, Guerra, E, Leandro-García, LJ, Cascón, A, Johansson, I, Robledo, M, Ingelman-Sundberg, M, Rodríguez-Antona, C .

VEGF, VEGFR3, and PDGFRB protein expression is influenced by RAS mutations in medullary thyroid carcinoma.

Mancikova, V, Inglada-Pérez, L, Curras-Freixes, M, de Cubas, AA, Gómez, Á, Letón, R, Kersten, I, Leandro-García, LJ, Comino-Méndez, I, Apellaniz-Ruiz, M, Sánchez, L, Cascón, A, Sastre-Marcos, J, García, JF, Rodríguez-Antona, C , Robledo, M.

Identification of tissue microRNAs predictive of sunitinib activity in patients with metastatic renal cell carcinoma.

Prior, C, Perez-Gracia, JL, Garcia-Donas, J, Rodriguez-Antona, C , Guruceaga, E, Esteban, E, Suarez, C, Castellano, D, del Alba, AG, Lozano, MD, Carles, J, Climent, MA, Arranz, JA, Gallardo, E, Puente, J, Bellmunt, J, Gurpide, A, Lopez-Picazo, JM, Hernandez, AG, Mellado, B, Martínez, E, Moreno, F, Font, A, Calvo, A.

Genome-wide association study identifies ephrin type A receptors implicated in paclitaxel induced peripheral sensory neuropathy.

Leandro-García, LJ, Inglada-Pérez, L, Pita, G, Hjerpe, E, Leskelä, S, Jara, C, Mielgo, X, González-Neira, A, Robledo, M, Avall-Lundqvist, E, Gréen, H, Rodríguez-Antona, C .

Prospective study assessing hypoxia-related proteins as markers for the outcome of treatment with sunitinib in advanced clear-cell renal cell carcinoma.

Garcia-Donas, J, Leandro-García, LJ, González Del Alba, A, Morente, M, Alemany, I, Esteban, E, Arranz, JA, Climent, MA, Gallardo, E, Castellano, DE, Bellmunt, J, Mellado, B, Puente, J, Moreno, F, Font, A, Hernando, S, Robledo, M, Rodríguez-Antona, C .

Influence of RET mutations on the expression of tyrosine kinases in medullary thyroid carcinoma.

Rodríguez-Antona, C , Muñoz-Repeto, I, Inglada-Pérez, L, de Cubas, AA, Mancikova, V, Cañamero, M, Maliszewska, A, Gómez, A, Letón, R, Leandro-García, LJ, Comino-Méndez, I, Sanchez, L, Alvarez-Escolá, C, Aller, J, Cascón, A, Robledo, M.

Integrative analysis of miRNA and mRNA expression profiles in pheochromocytoma and paraganglioma identifies genotype-specific markers and potentially regulated pathways.

de Cubas, AA, Leandro-García, LJ, Schiavi, F, Mancikova, V, Comino-Méndez, I, Inglada-Pérez, L, Perez-Martinez, M, Ibarz, N, Ximénez-Embún, P, López-Jiménez, E, Maliszewska, A, Letón, R, Gómez Graña, A, Bernal, C, Alvarez-Escolá, C, Rodríguez-Antona, C , Opocher, G, Muñoz, J, Megias, D, Cascón, A, Robledo, M.

Tumoral EPAS1 (HIF2A) mutations explain sporadic pheochromocytoma and paraganglioma in the absence of erythrocytosis.

Comino-Méndez, I, de Cubas, AA, Bernal, C, Álvarez-Escolá, C, Sánchez-Malo, C, Ramírez-Tortosa, CL, Pedrinaci, S, Rapizzi, E, Ercolino, T, Bernini, G, Bacca, A, Letón, R, Pita, G, Alonso, MR, Leandro-García, LJ, Gómez-Graña, A, Inglada-Pérez, L, Mancikova, V, Rodríguez-Antona, C , Mannelli, M, Robledo, M, Cascón, A.

Differential gene expression of medullary thyroid carcinoma reveals specific markers associated with genetic conditions.

Maliszewska, A, Leandro-Garcia, LJ, Castelblanco, E, Macià, A, de Cubas, A, Goméz-López, G, Inglada-Pérez, L, Álvarez-Escolá, C, De la Vega, L, Letón, R, Gómez-Graña, Á, Landa, I, Cascón, A, Rodríguez-Antona, C , Borrego, S, Zane, M, Schiavi, F, Merante-Boschin, I, Pelizzo, MR, Pisano, DG, Opocher, G, Matias-Guiu, X, Encinas, M, Robledo, M.

Hematologic β-tubulin VI isoform exhibits genetic variability that influences paclitaxel toxicity.

Leandro-García, LJ, Leskelä, S, Inglada-Pérez, L, Landa, I, de Cubas, AA, Maliszewska, A, Comino-Méndez, I, Letón, R, Gómez-Graña, Á, Torres, R, Ramírez, JC, Álvarez, S, Rivera, J, Martínez, C, Lozano, ML, Cascón, A, Robledo, M, Rodríguez-Antona, C .

Regulatory polymorphisms in β-tubulin IIa are associated with paclitaxel-induced peripheral neuropathy.

Leandro-García, LJ, Leskelä, S, Jara, C, Gréen, H, Avall-Lundqvist, E, Wheeler, HE, Dolan, ME, Inglada-Perez, L, Maliszewska, A, de Cubas, AA, Comino-Méndez, I, Mancikova, V, Cascón, A, Robledo, M, Rodríguez-Antona, C .

Detection of the first gross CDC73 germline deletion in an HPT-JT syndrome family.

Cascón, A, Huarte-Mendicoa, CV, Javier Leandro-García, L, Letón, R, Suela, J, Santana, A, Costa, MB, Comino-Méndez, I, Landa, I, Sánchez, L, Rodríguez-Antona, C , Cigudosa, JC, Robledo, M.

Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study.

Garcia-Donas, J, Esteban, E, Leandro-García, LJ, Castellano, DE, González del Alba, A, Climent, MA, Arranz, JA, Gallardo, E, Puente, J, Bellmunt, J, Mellado, B, Martínez, E, Moreno, F, Font, A, Robledo, M, Rodríguez-Antona, C .

Exome sequencing identifies MAX mutations as a cause of hereditary pheochromocytoma.

Comino-Méndez, I, Gracia-Aznárez, FJ, Schiavi, F, Landa, I, Leandro-García, LJ, Letón, R, Honrado, E, Ramos-Medina, R, Caronia, D, Pita, G, Gómez-Graña, A, de Cubas, AA, Inglada-Pérez, L, Maliszewska, A, Taschin, E, Bobisse, S, Pica, G, Loli, P, Hernández-Lavado, R, Díaz, JA, Gómez-Morales, M, González-Neira, A, Roncador, G, Rodríguez-Antona, C , Benítez, J, Mannelli, M, Opocher, G, Robledo, M, Cascón, A.

Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity.

Leskelä, S, Jara, C, Leandro-García, LJ, Martínez, A, García-Donas, J, Hernando, S, Hurtado, A, Vicario, JC, Montero-Conde, C, Landa, I, López-Jiménez, E, Cascón, A, Milne, RL, Robledo, M, Rodríguez-Antona, C .

The miR-200 family controls beta-tubulin III expression and is associated with paclitaxel-based treatment response and progression-free survival in ovarian cancer patients.

Leskelä, S, Leandro-García, LJ, Mendiola, M , Barriuso, J, Inglada-Pérez, L, Muñoz, I, Martínez-Delgado, B, Redondo, A, de Santiago, J, Robledo, M, Hardisson, D, Rodríguez-Antona, C .

Research resource: Transcriptional profiling reveals different pseudohypoxic signatures in SDHB and VHL-related pheochromocytomas.

López-Jiménez, E, Gómez-López, G, Leandro-García, LJ, Muñoz, I, Schiavi, F, Montero-Conde, C , de Cubas, AA, Ramires, R, Landa, I, Leskelä, S, Maliszewska, A, Inglada-Pérez, L, de la Vega, L, Rodríguez-Antona, C , Letón, R, Bernal, C, de Campos, JM, Diez-Tascón, C, Fraga, MF, Boullosa, C, Pisano, DG, Opocher, G, Robledo, M, Cascón, A.

Overexpression and activation of EGFR and VEGFR2 in medullary thyroid carcinomas is related to metastasis.

Rodríguez-Antona, C , Pallares, J, Montero-Conde, C , Inglada-Pérez, L, Castelblanco, E, Landa, I, Leskelä, S, Leandro-García, LJ, López-Jiménez, E, Letón, R, Cascón, A, Lerma, E, Martin, MC, Carralero, MC, Mauricio, D, Cigudosa, JC, Matias-Guiu, X, Robledo, M.

The hematopoietic-specific beta1-tubulin is naturally resistant to 2-methoxyestradiol and protects patients from drug-induced myelosuppression.

Escuin, D, Burke, PA, McMahon-Tobin, G, Hembrough, T, Wang, Y, Alcaraz, AA, Leandro-García, LJ, Rodríguez-Antona, C , Snyder, JP, Lavallee, TM, Giannakakou, P.

The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.

Landa, I, Ruiz-Llorente, S , Montero-Conde, C , Inglada-Pérez, L, Schiavi, F, Leskelä, S, Pita, G, Milne, R, Maravall, J, Ramos, I, Andía, V, Rodríguez-Poyo, P, Jara-Albarrán, A, Meoro, A, del Peso, C, Arribas, L, Iglesias, P, Caballero, J, Serrano, J, Picó, A, Pomares, F, Giménez, G, López-Mondéjar, P, Castello, R, Merante-Boschin, I, Pelizzo, MR, Mauricio, D, Opocher, G, Rodríguez-Antona, C , González-Neira, A, Matías-Guiu, X, Santisteban, P , Robledo, M.

Rationalization of genetic testing in patients with apparently sporadic pheochromocytoma/paraganglioma.

Cascón, A, López-Jiménez, E, Landa, I, Leskelä, S, Leandro-García, LJ, Maliszewska, A, Letón, R, de la Vega, L, García-Barcina, MJ, Sanabria, C, Alvarez-Escolá, C, Rodríguez-Antona, C , Robledo, M.

Genetics of pheochromocytoma and paraganglioma in Spanish patients.

Cascón, A, Pita, G, Burnichon, N, Landa, I, López-Jiménez, E, Montero-Conde, C , Leskelä, S, Leandro-García, LJ, Letón, R, Rodríguez-Antona, C , Díaz, JA, López-Vidriero, E, González-Neira, A, Velasco, A, Matias-Guiu, X, Gimenez-Roqueplo, AP, Robledo, M.

CYP2D6 genotyping for psychiatric patients treated with risperidone: considerations for cost-effectiveness studies.

Rodríguez-Antona, C , Gurwitz, D, de Leon, J, Llerena, A, Kirchheiner, J, de Mesa, EG, Ibarreta, D.

Molecular characterisation of a common SDHB deletion in paraganglioma patients.

Cascón, A, Landa, I, López-Jiménez, E, Díez-Hernández, A, Buchta, M, Montero-Conde, C, Leskelä, S, Leandro-García, LJ, Letón, R, Rodríguez-Antona, C , Eng, C, Neumann, HP, Robledo, M.

Cytochrome P450 3A5 is highly expressed in normal prostate cells but absent in prostate cancer.

Leskelä, S, Honrado, E, Montero-Conde, C, Landa, I, Cascón, A, Letón, R, Talavera, P, Cózar, JM, Concha, A, Robledo, M, Rodríguez-Antona, C .

Novel aspects of drug metabolism and transport.

Afzelius, L, Ingelman-Sundberg, M, Karlgren, M, Rodriguez-Antona, C .

New approaches and applications in chemical biology.

Gomez, A, Ingelman-Sundberg, M, Johansson, I, Karlgren, M, Rodriguez-Antona, C , Sim, SC.

Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein alpha and hepatocyte nuclear factor-3 gamma.

Rodríguez-Antona, C , Bort, R, Jover, R, Tindberg, N, Ingelman-Sundberg, M, Gómez-Lechón, MJ, Castell, JV.

CYP2A5/CYP2A6 expression in mouse and human hepatocytes treated with various in vivo inducers.

Donato, MT, Viitala, P, Rodriguez-Antona, C , Lindfors, A, Castell, JV, Raunio, H, Gómez-Lechón, MJ, Pelkonen, O.