23 ene | 2025 Vascular HIF2 Signaling Prevents Cardiomegaly, Alveolar Congestion, and Capillary Remodeling During Chronic Hypoxia. Albendea-Gomez, T, Mendoza-Tamajon, S, Castro-Mecinas, R, Escobar, B, Rocha, SF, Urra-Balduz, S, Nicolas-Avila, JA, Oliver, E, Villalba-Orero, M, Martin-Puig, S . Arterioscler Thromb Vasc Biol (PMID: 39846162) (doi:10.1161/ATVBAHA.124.321780)
17 jun | 2024 Cardiac Metabolism. Martin-Puig, S , Menendez-Montes, I. Adv Exp Med Biol - 1441 : 365-396 (PMID: 38884721) (doi:10.1007/978-3-031-44087-8_19)
17 dic | 2021 Embryonic echocardiography for assessment of congenital and functional cardiac defects. Menendez-Montes, I, Villalba-Orero, M, Escobar, B, Martin-Puig, S . STAR Protoc - 2 (4) : 100980 (PMID: 34927090) (doi:10.1016/j.xpro.2021.100980)
19 feb | 2021 Activation of amino acid metabolic program in cardiac HIF1-alpha-deficient mice. Menendez-Montes, I, Escobar, B, Gomez, MJ, Albendea-Gomez, T, Palacios, B, Bonzon-Kulichenko, E, Izquierdo-Garcia, JL, Alonso, AV, Ferrarini, A, Jimenez-Borreguero, LJ, Ruiz-Cabello, J, Vázquez, J, Martin-Puig, S . iScience - 24 (2) : 102124 (PMID: 33665549) (doi:10.1016/j.isci.2021.102124)
15 ago | 2018 Metabolic Reprogramming in the Heart and Lung in a Murine Model of Pulmonary Arterial Hypertension. Izquierdo-Garcia, JL, Arias, T, Rojas, Y, Garcia-Ruiz, V, Santos, A, Martin-Puig, S , Ruiz-Cabello, J. Front Cardiovasc Med - 5 : 110 (PMID: 30159317) (doi:10.3389/fcvm.2018.00110)
14 ago | 2018 Von Hippel-Lindau Protein Is Required for Optimal Alveolar Macrophage Terminal Differentiation, Self-Renewal, and Function. Izquierdo, HM, Brandi, P, Gómez, MJ, Conde-Garrosa, R, Priego, E, Enamorado, M, Martínez-Cano, S, Sánchez, I, Conejero, L, Jimenez-Carretero, D, Martín-Puig, S , Guilliams, M, Sancho, D. Cell Rep - 24 (7) : 1738-1746 (PMID: 30110631) (doi:10.1016/j.celrep.2018.07.034)
8 feb | 2018 SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2α. Mira, E, Carmona-Rodríguez, L, Pérez-Villamil, B, Casas, J, Fernández-Aceñero, MJ, Martínez-Rey, D, Martín-González, P, Heras-Murillo, I, Paz-Cabezas, M, Tardáguila, M , Oury, TD, Martín-Puig, S , Lacalle, RA, Fabriás, G, Díaz-Rubio, E, Mañes, S. Nat Commun - 9 (1) : 575 (PMID: 29422508) (doi:10.1038/s41467-018-03079-1)
19 dic | 2016 Myocardial VHL-HIF Signaling Controls an Embryonic Metabolic Switch Essential for Cardiac Maturation. Menendez-Montes, I, Escobar, B, Palacios, B, Gómez, MJ, Izquierdo-Garcia, JL, Flores, L, Jiménez-Borreguero, LJ, Aragones, J, Ruiz-Cabello, J, Torres, M, Martin-Puig, S . Dev Cell - 39 (6) : 724-739 (PMID: 27997827) (doi:10.1016/j.devcel.2016.11.012)
20 mayo | 2015 Novel perspectives on the PHD-HIF oxygen sensing pathway in cardioprotection mediated by IPC and RIPC. Martin-Puig, S , Tello, D, Aragonés, J. Front Physiol - 6 : 137 (PMID: 26042040) (doi:10.3389/fphys.2015.00137)
1 abr | 2012 Heart repair: from natural mechanisms of cardiomyocyte production to the design of new cardiac therapies. Martin-Puig, S , Fuster, V, Torres, M. Ann N Y Acad Sci - 1254 : 71-81 (PMID: 22548572) (doi:10.1111/j.1749-6632.2012.06488.x)
2 jul | 2009 Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages. Bu, L, Jiang, X, Martin-Puig, S , Caron, L, Zhu, S, Shao, Y, Roberts, DJ, Huang, PL, Domian, IJ, Chien, KR. Nature - 460 (7251) : 113-117 (PMID: 19571884) (doi:10.1038/nature08191)
1 mar | 2009 Macrophage oxygen sensing modulates antigen presentation and phagocytic functions involving IFN-gamma production through the HIF-1 alpha transcription factor. Acosta-Iborra, B , Elorza, A, Olazabal, IM, Martín-Cofreces, NB, Martin-Puig, S , Miró, M, Calzada, MJ, Aragonés, J, Sánchez-Madrid, F, Landázuri, MO. J Immunol - 182 (5) : 3155-3164 (PMID: 19234213) (doi:10.4049/jimmunol.0801710)
10 abr | 2008 Lives of a heart cell: tracing the origins of cardiac progenitors. Martin-Puig, S , Wang, Z, Chien, KR. Cell Stem Cell - 2 (4) : 320-331 (PMID: 18397752) (doi:10.1016/j.stem.2008.03.010)
16 ago | 2007 The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway. Qyang, Y, Martin-Puig, S , Chiravuri, M, Chen, S, Xu, H, Bu, L, Jiang, X, Lin, L, Granger, A, Moretti, A, Caron, L, Wu, X, Clarke, J, Taketo, MM, Laugwitz, KL, Moon, RT, Gruber, P, Evans, SM, Ding, S, Chien, KR. Cell Stem Cell - 1 (2) : 165-179 (PMID: 18371348) (doi:10.1016/j.stem.2007.05.018)
15 dic | 2006 Multipotent embryonic isl1+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Moretti, A, Caron, L, Nakano, A, Lam, JT, Bernshausen, A, Chen, Y, Qyang, Y, Bu, L, Sasaki, M, Martin-Puig, S , Sun, Y, Evans, SM, Laugwitz, KL, Chien, KR. Cell - 127 (6) : 1151-1165 (PMID: 17123592) (doi:10.1016/j.cell.2006.10.029)
24 jun | 2005 Activation of HIF-prolyl hydroxylases by R59949, an inhibitor of the diacylglycerol kinase. Temes, E, Martín-Puig, S , Acosta-Iborra, B , Castellanos, MC, Feijoo-Cuaresma, M, Olmos, G, Aragonés, J, Landazuri, MO. J Biol Chem - 280 (25) : 24238-24244 (PMID: 15849364) (doi:10.1074/jbc.M414694200)
5 mar | 2004 Role of iron (II)-2-oxoglutarate-dependent dioxygenases in the generation of hypoxia-induced phosphatidic acid through HIF-1/2 and von Hippel-Lindau-independent mechanisms. Martín-Puig, S , Temes, E, Olmos, G, Jones, DR, Aragonés, J, Landázuri, MO. J Biol Chem - 279 (10) : 9504-9511 (PMID: 14681229) (doi:10.1074/jbc.M310658200)
27 feb | 2004 Role of diacylglycerol induced by hypoxia in the regulation of HIF-1alpha activity. Temes, E, Martín-Puig, S , Aragonés, J, Jones, DR, Olmos, G, Mérida, I, Landázuri, MO. Biochem Biophys Res Commun - 315 (1) : 44-50 (PMID: 15013423) (doi:10.1016/j.bbrc.2004.01.015)
5 dic | 2003 The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen. del Peso, L , Castellanos, MC, Temes, E, Martin-Puig, S , Cuevas, Y, Olmos, G, Landazuri, MO. J. Biol. Chem. - 278 (49) : 48690-48695 (PMID: 14506252) (doi:10.1074/jbc.M308862200)
15 oct | 2003 Specific oncolytic effect of a new hypoxia-inducible factor-dependent replicative adenovirus on von Hippel-Lindau-defective renal cell carcinomas. Cuevas, Y, Hernández-Alcoceba, R, Aragones, J, Naranjo-Suárez, S, Castellanos, MC, Esteban, MA, Martín-Puig, S , Landazuri, MO, del Peso, L . Cancer Res. - 63 (20) : 6877-6884 (PMID: 14583486)
30 mar | 2001 Evidence for the involvement of diacylglycerol kinase in the activation of hypoxia-inducible transcription factor 1 by low oxygen tension. Aragonés, J, Jones, DR, Martin, S , San Juan, MA, Alfranca, A, Vidal, F, Vara, A, Mérida, I, Landázuri, MO. J Biol Chem - 276 (13) : 10548-10555 (PMID: 11136721) (doi:10.1074/jbc.M006180200)