1 Nov | 2025 FOXO Transcription Factors: A Brief Overview. Link, W , Ferreira, BI. Methods Mol Biol - 2871 : 1-8 (PMID: 39565573) (doi:10.1007/978-1-0716-4217-7_1)
1 Nov | 2025 Immunocytochemistry-Based Detection of FOXO Isoforms in Human Cancer and Fibroblasts. Jimenez, L , Domínguez, L, Amenabar, C , Serrão, G, Link, W , Ferreira, BI, Santos, B. Methods Mol Biol - 2871 : 171-176 (PMID: 39565588) (doi:10.1007/978-1-0716-4217-7_16)
1 Nov | 2025 Measuring FOXO Activity by Using qPCR-Based Expression Analysis of FOXO Target Genes. Jimenez, L , Grenho, I, Santos, B, Serrão, G, Mayoral-Varo, V , Link, W , Ferreira, BI. Methods Mol Biol - 2871 : 33-43 (PMID: 39565576) (doi:10.1007/978-1-0716-4217-7_4)
1 Nov | 2025 Multiplexed Dual-Color Fluorescence-Based Distinction Between Nuclear Trapping and Translocation of FOXO3. Amenabar, C , Jimenez, L , Mourato, C, Mayoral-Varo, V , Megías, D, Ferreira, BI, Link, W . Methods Mol Biol - 2871 : 163-170 (PMID: 39565587) (doi:10.1007/978-1-0716-4217-7_15)
1 Nov | 2025 Reporter Gene Assays to Measure FOXO-Specific Transcriptional Activity. Santos, B, Orea-Soufi, A, Mayoral-Varo, V , Link, W , Jimenez, L . Methods Mol Biol - 2871 : 45-53 (PMID: 39565577) (doi:10.1007/978-1-0716-4217-7_5)
6 Dec | 2023 Correction: FOXO family isoforms. Santos, BF, Grenho, I, Martel, PJ, Ferreira, BI, Link, W . Cell Death Dis - 14 (12) : 797 (PMID: 38057340) (doi:10.1038/s41419-023-06328-4)
27 Oct | 2023 FOXO family isoforms. Santos, BF, Grenho, I, Martel, PJ, Ferreira, BI, Link, W . Cell Death Dis - 14 (10) : 702 (PMID: 37891184) (doi:10.1038/s41419-023-06177-1)
9 Jul | 2023 Pseudokinases, Tribbles Proteins and Cancer. Velasco, G, Link, W . Cancers (Basel) - 15 (14) (PMID: 37509210) (doi:10.3390/cancers15143547)
6 Jan | 2023 FOXO1 represses PPARα-Mediated induction of FGF21 gene expression. De Sousa-Coelho, AL, Gacias, M, O'Neill, BT, Relat, J, Link, W , Haro, D, Marrero, PF. Biochem Biophys Res Commun - 644 : 122-129 (PMID: 36640666) (doi:10.1016/j.bbrc.2023.01.012)
10 Nov | 2022 Multiplexed cellular profiling identifies an organoselenium compound as an inhibitor of CRM1-mediated nuclear export. Jimenez, L , Mayoral-Varo, V , Amenábar, C , Ortega, J , Sequeira, JGN, Machuqueiro, M, Mourato, C, Silvestri, R, Angeli, A, Carta, F, Supuran, CT, Megías, D, Ferreira, BI, Link, W . Traffic (PMID: 36353954) (doi:10.1111/tra.12872)
21 Oct | 2022 FOXO transcription factors as therapeutic targets in human diseases. Orea-Soufi, A, Paik, J, Bragança, J, Donlon, TA, Willcox, BJ, Link, W . Trends Pharmacol Sci (PMID: 36280450) (doi:10.1016/j.tips.2022.09.010)
24 Aug | 2022 mTORC2 Is the Major Second Layer Kinase Negatively Regulating FOXO3 Activity. Jimenez, L , Amenabar, C , Mayoral-Varo, V , Mackenzie, TA, Ramos, MC, Silva, A, Calissi, G , Grenho, I, Blanco-Aparicio, C, Pastor, J, Megías, D, Ferreira, BI, Link, W . Molecules - 27 (17) (PMID: 36080182) (doi:10.3390/molecules27175414)
8 Jul | 2022 Decavanadate and metformin-decavanadate effects in human melanoma cells. De Sousa-Coelho, AL, Aureliano, M, Fraqueza, G, Serrão, G, Gonçalves, J, Sánchez-Lombardo, I, Link, W , Ferreira, BI. J Inorg Biochem - 235 : 111915 (PMID: 35834898) (doi:10.1016/j.jinorgbio.2022.111915)
17 Dec | 2021 DNA Methylation of PI3K/AKT Pathway-Related Genes Predicts Outcome in Patients with Pancreatic Cancer: A Comprehensive Bioinformatics-Based Study. Faleiro, I, Roberto, VP, Demirkol Canli, S, Fraunhoffer, NA, Iovanna, J, Gure, AO, Link, W , Castelo-Branco, P. Cancers (Basel) - 13 (24) (PMID: 34944974) (doi:10.3390/cancers13246354)
3 Dec | 2021 Modulating undruggable targets to overcome cancer therapy resistance. Passirani, C, Vessières, A, La Regina, G, Link, W , Silvestri, R. Drug Resist Updat - 60 : 100788 (PMID: 35168144) (doi:10.1016/j.drup.2021.100788)
11 Sep | 2021 Screening health-promoting compounds for their capacity to induce the activity of FOXO3. Jimenez, L , Silva, A, Calissi, G , Grenho, I, Monteiro, R, Mayoral-Varo, V , Blanco-Aparicio, C, Pastor, J, Bustos, V, Bracher, F, Megías, D, Ferreira, BI, Link, W . J Gerontol A Biol Sci Med Sci (PMID: 34508571) (doi:10.1093/gerona/glab265)
13 Aug | 2021 Editorial: Tumor Microenvironment: Molecular Mechanisms and Signaling Pathways Involved in Metastatic Progression. Link, W , Ilardi, G, Zannetti, A. Front Oncol - 11 : 730815 (PMID: 34485160) (doi:10.3389/fonc.2021.730815)
5 Jun | 2021 Tribbles Pseudokinases in Colorectal Cancer. Ferreira, BI, Santos, B, Link, W , De Sousa-Coelho, AL. Cancers (Basel) - 13 (11) (PMID: 34198908) (doi:10.3390/cancers13112825)
30 May | 2021 The Critical Role of TRIB2 in Cancer and Therapy Resistance. Mayoral-Varo, V , Jiménez, L , Link, W . Cancers (Basel) - 13 (11) (PMID: 34070799) (doi:10.3390/cancers13112701)
1 Apr | 2021 One-minute and green synthesis of magnetic iron oxide nanoparticles assisted by design of experiments and high energy ultrasound: Application to biosensing and immunoprecipitation. Pérez-Beltrán, CH, García-Guzmán, JJ, Ferreira, B, Estévez-Hernández, O, López-Iglesias, D, Cubillana-Aguilera, L, Link, W , Stănică, N, Rosa da Costa, AM, Palacios-Santander, JM. Mater Sci Eng C Mater Biol Appl - 123 : 112023 (PMID: 33812640) (doi:10.1016/j.msec.2021.112023)
9 Dec | 2020 Harmine and Piperlongumine Revert TRIB2-Mediated Drug Resistance. Machado, S, Silva, A, De Sousa-Coelho, AL, Duarte, I, Grenho, I, Santos, B, Mayoral-Varo, V , Megias, D, Sánchez-Cabo, F, Dopazo, A, Ferreira, BI, Link, W . Cancers (Basel) - 12 (12) (PMID: 33316942) (doi:10.3390/cancers12123689)
10 Nov | 2020 Therapeutic strategies targeting FOXO transcription factors. Calissi, G , Lam, EW, Link, W . Nat Rev Drug Discov (PMID: 33173189) (doi:10.1038/s41573-020-0088-2)
7 May | 2020 Small Molecule Inhibitors of CRM1. Ferreira, BI, Cautain, B, Grenho, I, Link, W . Front Pharmacol - 11 : 625 (PMID: 32574233) (doi:10.3389/fphar.2020.00625)
25 Feb | 2020 CRISPR/Cas9-mediated genome editing: From basic research to translational medicine. Jacinto, FV, Link, W , Ferreira, BI. J. Cell. Mol. Med. (PMID: 32096600) (doi:10.1111/jcmm.14916)
1 Nov | 2019 High-Throughput Image-Based Screening to Identify Chemical Compounds Capable of Activating FOXO. Barradas, M, Link, W , Megias, D, Fernandez-Marcos, PJ. Methods Mol. Biol. - 1890 : 151-161 (PMID: 30414152) (doi:10.1007/978-1-4939-8900-3_13)
1 Nov | 2019 Introduction to FOXO Biology. Link, W . Methods Mol. Biol. - 1890 : 1-9 (PMID: 30414140) (doi:10.1007/978-1-4939-8900-3_1)
1 Nov | 2019 Monitoring the Transcriptional Activity of FOXO Transcription Factors by Analyzing their Target Genes. Henriques, V, Machado, S, Link, W , Ferreira, BI. Methods Mol. Biol. - 1890 : 103-113 (PMID: 30414148) (doi:10.1007/978-1-4939-8900-3_9)
5 Jun | 2019 Image-based Identification of Chemical Compounds Capable of Trapping FOXO in the Cell Nucleus. Machado, S, Raposo, C, Ferreira, BI, Link, W . Methods Mol. Biol. - 1890 : 163-170 (PMID: 30414153) (doi:10.1007/978-1-4939-8900-3_14)
1 Dec | 2018 The Emerging Therapeutic Landscape of Advanced Melanoma. Henriques, V, Martins, T, Link, W , Ferreira, BI. Curr Pharm Des - 24 (5) : 549-558 (PMID: 29366407) (doi:10.2174/1381612824666180125093357)
1 Aug | 2018 Knowledge-based drug discovery intensifies private appropriation of publicly financed research. Link, W . Lancet Oncol. - 19 (8) : 1017-1018 (PMID: 30102212) (doi:10.1016/S1470-2045(18)30437-6)
15 Dec | 2017 FOXO transcription factors at the interface of metabolism and cancer. Link, W , Fernandez-Marcos, PJ. Int J Cancer - 141 (12) : 2379-2391 (PMID: 28631330) (doi:10.1002/ijc.30840)
1 Jun | 2017 Immunology: Mind the immuno-connection gap. Link, W . Nat Chem Biol - 13 (6) : 572-573 (PMID: 28437396) (doi:10.1038/nchembio.2373)
9 Mar | 2017 TRIB2 confers resistance to anti-cancer therapy by activating the serine/threonine protein kinase AKT. Hill, R, Madureira, PA, Ferreira, B, Baptista, I, Machado, S, Colaço, L, Dos Santos, M, Liu, N, Dopazo, A, Ugurel, S, Adrienn, A, Kiss-Toth, E, Isbilen, M, Gure, AO, Link, W . Nat Commun - 8 : 14687 (PMID: 28276427) (doi:10.1038/ncomms14687)
1 Jan | 2017 Adaptive mechanisms of resistance to anti-neoplastic agents. Ferreira, BI, Lie, MK, Engelsen, AST, Machado, S, Link, W , Lorens, JB. Medchemcomm - 8 (1) : 53-66 (PMID: 30108690) (doi:10.1039/c6md00394j)
9 Dec | 2016 Discovery of a Novel, Isothiazolonaphthoquinone-Based Small Molecule Activator of FOXO Nuclear-Cytoplasmic Shuttling. Cautain, B, Castillo, F, Musso, L, Ferreira, BI, de Pedro, N, Rodriguez Quesada, L, Machado, S, Vicente, F, Dallavalle, S, Link, W . PLoS One - 11 (12) : e0167491 (PMID: 27936162) (doi:10.1371/journal.pone.0167491)
15 Sep | 2016 Special Review: Caught in the Crosshairs: Targeted Drugs and Personalized Medicine. Ferreira, BI, Hill, R, Link, W . Cancer J - 21 (6) : 441-447 (PMID: 26588674) (doi:10.1097/PPO.0000000000000161)
1 Apr | 2016 Long live FOXO: unraveling the role of FOXO proteins in aging and longevity. Martins, R, Lithgow, GJ, Link, W . Aging Cell - 15 (2) : 196-207 (PMID: 26643314) (doi:10.1111/acel.12427)
1 Dec | 2015 Methylseleninic acid promotes antitumour effects via nuclear FOXO3a translocation through Akt inhibition. Tarrado-Castellarnau, M, Cortés, R, Zanuy, M, Tarragó-Celada, J, Polat, IH, Hill, R, Fan, TW, Link, W , Cascante, M. Pharmacol Res - 102 : 218-234 (PMID: 26375988) (doi:10.1016/j.phrs.2015.09.009)
9 Nov | 2015 Image-based identification of nuclear export inhibitors from natural products. Cautain, B, de Pedro, N, Reyes, F, Link, W . Methods Mol Biol - 1270 : 307-319 (PMID: 25702126) (doi:10.1007/978-1-4939-2309-0_22)
1 Oct | 2015 Tribbles breaking bad: TRIB2 suppresses FOXO and acts as an oncogenic protein in melanoma. Link, W . Biochem Soc Trans - 43 (5) : 1085-1088 (PMID: 26517928) (doi:10.1042/BST20150102)
1 Apr | 2015 TRIB2 as a biomarker for diagnosis and progression of melanoma. Hill, R, Kalathur, RK, Colaço, L, Brandão, R, Ugurel, S, Futschik, M, Link, W . Carcinogenesis - 36 (4) : 469-477 (PMID: 25586991) (doi:10.1093/carcin/bgv002)
1 Feb | 2015 Components and regulation of nuclear transport processes. Cautain, B, Hill, R, de Pedro, N, Link, W . FEBS J - 282 (3) : 445-462 (PMID: 25429850) (doi:10.1111/febs.13163)
1 May | 2014 Discovery of 14-3-3 protein-protein interaction inhibitors that sensitize multidrug-resistant cancer cells to doxorubicin and the Akt inhibitor GSK690693. Mori, M, Vignaroli, G, Cau, Y, Dinić, J, Hill, R, Rossi, M, Colecchia, D, Pešić, M, Link, W , Chiariello, M, Ottmann, C, Botta, M. ChemMedChem - 9 (5) : 973-983 (PMID: 24715717) (doi:10.1002/cmdc.201400044)
1 Mar | 2014 A novel cyclometallated Pt(II)-ferrocene complex induces nuclear FOXO3a localization and apoptosis and synergizes with cisplatin to inhibit lung cancer cell proliferation. Cortés, R, Tarrado-Castellarnau, M, Talancón, D, López, C, Link, W , Ruiz, D, Centelles, JJ, Quirante, J, Cascante, M. Metallomics - 6 (3) : 622-633 (PMID: 24492855) (doi:10.1039/c3mt00194f)
15 Jan | 2014 Targeting nucleocytoplasmic transport in cancer therapy. Hill, R, Cautain, B, de Pedro, N, Link, W . Oncotarget - 5 (1) : 11-28 (PMID: 24429466) (doi:10.18632/oncotarget.1457)
1 Jan | 2014 High-content screening of natural products reveals novel nuclear export inhibitors. Cautain, B, de Pedro, N, Murillo Garzón, V, Muñoz de Escalona, M, González Menéndez, V, Tormo, JR, Martin, J, El Aouad, N, Reyes, F, Asensio, F, Genilloud, O, Vicente, F, Link, W . J Biomol Screen - 19 (1) : 57-65 (PMID: 24045581) (doi:10.1177/1087057113501389)
1 Mar | 2013 Moving to the core: spatiotemporal analysis of Forkhead box O (FOXO) and nuclear factor-κB (NF-κB) nuclear translocation. Zanella, F, Dos Santos, NR, Link, W . Traffic - 14 (3) : 247-258 (PMID: 23231504) (doi:10.1111/tra.12034)
11 Feb | 2013 Image-based high-throughput screening for inhibitors of angiogenesis. Evensen, L, Link, W , Lorens, JB. Methods Mol Biol - 931 : 139-151 (PMID: 23027002) (doi:10.1007/978-1-62703-056-4_8)
1 Feb | 2013 Biological characterization of ETP-46321 a selective and efficacious inhibitor of phosphoinositide-3-kinases. Granda, TG, Cebrián, D, Martínez, S, Anguita, PV, López, EC, Link, W , Merino, T, Pastor, J, Serelde, BG, Peregrina, S, Palacios, I, Albarran, MI, Cebriá, A, Lorenzo, M, Alonso, P, Fominaya, J, López, AR, Bischoff, JR. Invest New Drugs - 31 (1) : 66-76 (PMID: 22623067) (doi:10.1007/s10637-012-9835-5)
26 Sep | 2012 Nuclear accumulation of β-catenin and forkhead box O3a in colon cancer: Dangerous liaison. Link, W . World J Biol Chem - 3 (9) : 175-179 (PMID: 23024836) (doi:10.4331/wjbc.v3.i9.175)
15 Aug | 2012 Rapid identification of ETP-46992, orally bioavailable PI3K inhibitor, selective versus mTOR. Martínez González, S, Hernández, AI, Varela, C, Lorenzo, M, Ramos-Lima, F, Cendón, E, Cebrián, D, Aguirre, E, Gomez-Casero, E, Albarrán, MI, Alfonso, P, García-Serelde, B, Mateos, G, Oyarzabal, J, Rabal, O, Mulero, F, Gonzalez-Granda, T, Link, W , Fominaya, J, Barbacid, M, Bischoff, JR, Pizcueta, P, Blanco-Aparicio, C, Pastor, J. Bioorg Med Chem Lett - 22 (16) : 5208-5214 (PMID: 22819764) (doi:10.1016/j.bmcl.2012.06.093)
15 May | 2012 Identification of ETP-46321, a potent and orally bioavailable PI3K α, δ inhibitor. Martínez González, S, Hernández, AI, Varela, C, Rodríguez-Arístegui, S, Lorenzo, M, Rodríguez, A, Rivero, V, Martín, JI, Saluste, CG, Ramos-Lima, F, Cendón, E, Cebrián, D, Aguirre, E, Gomez-Casero, E, Albarrán, M, Alfonso, P, García-Serelde, B, Oyarzabal, J, Rabal, O, Mulero, F, Gonzalez-Granda, T, Link, W , Fominaya, J, Barbacid, M, Bischoff, JR, Pizcueta, P, Pastor, J. Bioorg Med Chem Lett - 22 (10) : 3460-3466 (PMID: 22520259) (doi:10.1016/j.bmcl.2012.03.090)
1 Mar | 2012 Imidazo[1,2-a]pyrazines as novel PI3K inhibitors. Martínez González, S, Hernández, AI, Varela, C, Rodríguez-Arístegui, S, Alvarez, RM, García, AB, Lorenzo, M, Rivero, V, Oyarzabal, J, Rabal, O, Bischoff, JR, Albarrán, M, Cebriá, A, Alfonso, P, Link, W , Fominaya, J, Pastor, J. Bioorg Med Chem Lett - 22 (5) : 1874-1878 (PMID: 22325943) (doi:10.1016/j.bmcl.2012.01.074)
1 Jan | 2012 Identification of disease-relevant genes for molecularly-targeted drug discovery. Kauselmann, G, Dopazo, A, Link, W . Curr Cancer Drug Targets - 12 (1) : 1-13 (PMID: 22165964) (doi:10.2174/156800912798888947)
15 Oct | 2011 Protein localization in disease and therapy. Hung, MC, Link, W . J Cell Sci - 124 (Pt 20) : 3381-3392 (PMID: 22010196) (doi:10.1242/jcs.089110)
1 Aug | 2011 The therapeutic potential of FOXO proteins. Link, W . Curr Drug Targets - 12 (9) : 1232-1234 (PMID: 21443469) (doi:10.2174/138945011796150235)
1 Apr | 2011 Context-dependent therapeutic potential of FOXO proteins in oral squamous cell carcinoma. Link, W . Oral Oncol - 47 (4) : 229-230 (PMID: 21376658) (doi:10.1016/j.oraloncology.2011.02.008)
1 Dec | 2010 Imaged-based high-throughput screening for anti-angiogenic drug discovery. Evensen, L, Link, W , Lorens, JB. Curr Pharm Des - 16 (35) : 3958-3963 (PMID: 21158729) (doi:10.2174/138161210794455030)
20 May | 2010 Human TRIB2 is a repressor of FOXO that contributes to the malignant phenotype of melanoma cells. Zanella, F, Renner, O, García, B , Callejas, S, Dopazo, A, Peregrina, S, Carnero, A, Link, W . Oncogene - 29 (20) : 2973-2982 (PMID: 20208562) (doi:10.1038/onc.2010.58)
1 May | 2010 High content screening: seeing is believing. Zanella, F, Lorens, JB, Link, W . Trends Biotechnol - 28 (5) : 237-245 (PMID: 20346526) (doi:10.1016/j.tibtech.2010.02.005)
1 Apr | 2010 An integrated one-step system to extract, analyze and annotate all relevant information from image-based cell screening of chemical libraries. Rabal, O, Link, W , Serelde, BG, Bischoff, JR, Oyarzabal, J. Mol Biosyst - 6 (4) : 711-720 (PMID: 20237649) (doi:10.1039/b919830j)
1 Mar | 2010 Understanding FOXO, new views on old transcription factors. Zanella, F, Link, W , Carnero, A. Curr Cancer Drug Targets - 10 (2) : 135-146 (PMID: 20088800) (doi:10.2174/156800910791054158)
1 Jan | 2010 A novel imaging-based high-throughput screening approach to anti-angiogenic drug discovery. Evensen, L, Micklem, DR, Link, W , Lorens, JB. Cytometry A - 77 (1) : 41-51 (PMID: 19834964) (doi:10.1002/cyto.a.20808)
9 Oct | 2009 Chemical interrogation of FOXO3a nuclear translocation identifies potent and selective inhibitors of phosphoinositide 3-kinases. Link, W , Oyarzabal, J, Serelde, BG, Albarran, MI, Rabal, O, Cebriá, A, Alfonso, P, Fominaya, J, Renner, O, Peregrina, S, Soilán, D, Ceballos, PA, Hernández, AI, Lorenzo, M, Pevarello, P, Granda, TG, Kurz, G, Carnero, A, Bischoff, JR. J Biol Chem - 284 (41) : 28392-28400 (PMID: 19690175) (doi:10.1074/jbc.M109.038984)
25 Feb | 2009 Using multiplexed regulation of luciferase activity and GFP translocation to screen for FOXO modulators. Zanella, F, Rosado, A, Garcia, B, Carnero, A, Link, W . BMC Cell Biol - 10 : 14 (PMID: 19243599) (doi:10.1186/1471-2121-10-14)
22 Sep | 2008 Chemical genetic analysis of FOXO nuclear-cytoplasmic shuttling by using image-based cell screening. Zanella, F, Rosado, A, García, B, Carnero, A, Link, W . Chembiochem - 9 (14) : 2229-2237 (PMID: 18756565) (doi:10.1002/cbic.200800255)
1 May | 2008 The PTEN/PI3K/AKT signalling pathway in cancer, therapeutic implications. Carnero, A, Blanco-Aparicio, C, Renner, O, Link, W , Leal, JF. Curr Cancer Drug Targets - 8 (3) : 187-198 (PMID: 18473732) (doi:10.2174/156800908784293659)
19 Mar | 2008 A dual-color fluorescence-based platform to identify selective inhibitors of Akt signaling. Rosado, A, Zanella, F, Garcia, B, Carnero, A, Link, W . PLoS One - 3 (3) : e1823 (PMID: 18350159) (doi:10.1371/journal.pone.0001823)
1 Dec | 2007 MAP17 inhibits Myc-induced apoptosis through PI3K/AKT pathway activation. Guijarro, MV, Link, W , Rosado, A, Leal, JF, Carnero, A. Carcinogenesis - 28 (12) : 2443-2450 (PMID: 17675338) (doi:10.1093/carcin/bgm154)
1 Aug | 2007 Meeting report: trends and challenges in high content analysis. Liebel, U, Link, W . Biotechnol J - 2 (8) : 938-940 (PMID: 17680709) (doi:10.1002/biot.200700101)
1 Jun | 2007 An HTS approach to screen for antagonists of the nuclear export machinery using high content cell-based assays. Zanella, F, Rosado, A, Blanco, F, Henderson, BR, Carnero, A, Link, W . Assay Drug Dev Technol - 5 (3) : 333-341 (PMID: 17638533) (doi:10.1089/adt.2007.058)
1 Aug | 2005 Membrane localization of all class I PI 3-kinase isoforms suppresses c-Myc-induced apoptosis in Rat1 fibroblasts via Akt. Link, W , Rosado, A, Fominaya, J, Thomas, JE, Carnero, A. J Cell Biochem - 95 (5) : 979-989 (PMID: 15838873) (doi:10.1002/jcb.20479)
1 Dec | 2004 The BDNF gene: exemplifying complexity in Ca2+ -dependent gene expression. Mellstrom, B, Torres, B, Link, WA , Naranjo, JR. Crit Rev Neurobiol - 16 (1-2) : 43-49 (PMID: 15581398) (doi:10.1615/critrevneurobiol.v16.i12.40)
9 Jun | 2004 Day-night changes in downstream regulatory element antagonist modulator/potassium channel interacting protein activity contribute to circadian gene expression in pineal gland. Link, WA , Ledo, F, Torres, B, Palczewska, M, Madsen, TM, Savignac, M, Albar, JP, Mellström, B, Naranjo, JR. J Neurosci - 24 (23) : 5346-5355 (PMID: 15190107) (doi:10.1523/JNEUROSCI.1460-04.2004)
1 Jun | 2003 Overexpression of cyclin D1 inhibits TNF-induced growth arrest. Moneo, V, del Valle Guijarro, M, Link, W , Carnero, A. J Cell Biochem - 89 (3) : 484-499 (PMID: 12761882) (doi:10.1002/jcb.10529)
1 May | 2001 Interleukin 3-dependent activation of DREAM is involved in transcriptional silencing of the apoptotic Hrk gene in hematopoietic progenitor cells. Sanz, C , Mellstrom, B, Link, WA , Naranjo, JR, Fernandez-Luna, JL. EMBO J - 20 (9) : 2286-2292 (PMID: 11331593) (doi:10.1093/emboj/20.9.2286)
20 Dec | 2000 The DREAM-DRE interaction: key nucleotides and dominant negative mutants. Ledo, F, Link, WA , Carrión, AM, Echeverria, V, Mellström, B, Naranjo, JR. Biochim Biophys Acta - 1498 (2-3) : 162-168 (PMID: 11108959) (doi:10.1016/s0167-4889(00)00092-6)
1 Dec | 2000 DREAM-alphaCREM interaction via leucine-charged domains derepresses downstream regulatory element-dependent transcription. Ledo, F, Carrión, AM, Link, WA , Mellström, B, Naranjo, JR. Mol Cell Biol - 20 (24) : 9120-9126 (PMID: 11094064) (doi:10.1128/mcb.20.24.9120-9126.2000)
5 Oct | 2000 Induction of glycerol phosphate dehydrogenase gene expression during seizure and analgesia. Link, WA , Kauselmann, G, Mellström, B, Kuhl, D, Naranjo, JR. J Neurochem - 75 (4) : 1419-1428 (PMID: 10987821) (doi:10.1046/j.1471-4159.2000.0751419.x)
4 Mar | 1999 DREAM is a Ca2+-regulated transcriptional repressor. Carrión, AM, Link, WA , Ledo, F, Mellström, B, Naranjo, JR. Nature - 398 (6722) : 80-84 (PMID: 10078534) (doi:10.1038/18044)
6 Jun | 1995 Somatodendritic expression of an immediate early gene is regulated by synaptic activity. Link, W , Konietzko, U, Kauselmann, G, Krug, M, Schwanke, B, Frey, U, Kuhl, D. Proc Natl Acad Sci U S A - 92 (12) : 5734-5738 (PMID: 7777577) (doi:10.1073/pnas.92.12.5734)