28 Mar | 2025 Systemic rewiring of dendritic cells by melanoma-secreted midkine impairs immune surveillance and response to immune checkpoint blockade. Catena, X, Contreras-Alcalde, M, Juan-Larrea, N, Cerezo-Wallis, D, Calvo, TG, Mucientes, C, Olmeda, D , Suárez, J, Oterino-Sogo, S, Martínez, L, Megías, D, Sancho, D, Tejedo, C, Frago, S, Dudziak, D, Seretis, A, Stoitzner, P, Soengas, MS. Nat Cancer (PMID: 40155713) (doi:10.1038/s43018-025-00929-y)
7 Dec | 2021 Live imaging of neolymphangiogenesis identifies acute antimetastatic roles of dsRNA mimics. Olmeda, D , Cerezo-Wallis, D, Mucientes, C, Calvo, TG, Cañón, E , Alonso-Curbelo, D, Ibarz, N, Muñoz, J, Rodriguez-Peralto, JL, Ortiz-Romero, P, Ortega, S, Soengas, MS. EMBO Mol Med - 13 (12) : e12924 (PMID: 34762341) (doi:10.15252/emmm.202012924)
1 Aug | 2021 Physiological models for in vivo imaging and targeting the lymphatic system: Nanoparticles and extracellular vesicles. Olmeda, D , Cerezo-Wallis, D, Castellano-Sanz, E, García-Silva, S , Peinado, H , Soengas, MS. Adv Drug Deliv Rev - 175 : 113833 (PMID: 34147531) (doi:10.1016/j.addr.2021.113833)
1 Dec | 2020 Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state. Cerezo-Wallis, D, Contreras-Alcalde, M, Troulé, K, Catena, X, Mucientes, C, Calvo, TG, Cañón, E , Tejedo, C, Pennacchi, PC, Hogan, S, Kölblinger, P, Tejero, H, Chen, AX, Ibarz, N, Graña-Castro, O, Martinez, L, Muñoz, J, Ortiz-Romero, P, Rodriguez-Peralto, JL, Gómez-López, G, Al-Shahrour, F, Rabadán, R, Levesque, MP, Olmeda, D , Soengas, MS. Nat Med - 26 (12) : 1865-1877 (PMID: 33077955) (doi:10.1038/s41591-020-1073-3)
14 Jan | 2019 p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors. Karras, P, Riveiro-Falkenbach, E, Cañón, E , Tejedo, C, Calvo, TG, Martínez-Herranz, R, Alonso-Curbelo, D, Cifdaloz, M, Perez-Guijarro, E, Gómez-López, G, Ximenez-Embun, P, Muñoz, J, Megias, D, Olmeda, D , Moscat, J, Ortiz-Romero, PL, Rodríguez-Peralto, JL, Soengas, MS. Cancer Cell - 35 (1) : 46-63.e10 (PMID: 30581152) (doi:10.1016/j.ccell.2018.11.008)
21 Dec | 2017 Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1. Cifdaloz, M, Osterloh, L, Graña, O, Riveiro-Falkenbach, E, Ximénez-Embún, P, Muñoz, J, Tejedo, C, Calvo, TG, Karras, P, Olmeda, D , Miñana, B, Gómez-López, G, Cañon, E, Eyras, E, Guo, H, Kappes, F, Ortiz-Romero, PL, Rodríguez-Peralto, JL, Megías, D, Valcárcel, J, Soengas, MS. Nat Commun - 8 (1) : 2249 (PMID: 29269732) (doi:10.1038/s41467-017-02353-y)
28 Jun | 2017 Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine. Olmeda, D , Cerezo-Wallis, D, Riveiro-Falkenbach, E, Pennacchi, PC, Contreras-Alcalde, M, Ibarz, N, Cifdaloz, M, Catena, X, Calvo, TG, Cañón, E , Alonso-Curbelo, D, Suarez, J, Osterloh, L, Graña, O, Mulero, F, Megías, D, Cañamero, M, Martínez-Torrecuadrada, JL, Mondal, C, Di Martino, J, Lora, D, Martinez-Corral, I, Bravo-Cordero, JJ, Muñoz, J, Puig, S, Ortiz-Romero, P, Rodriguez-Peralto, JL, Ortega, S, Soengas, MS. Nature - 546 (7660) : 676-680 (PMID: 28658220) (doi:10.1038/nature22977)
14 Nov | 2016 UNR/CSDE1 Drives a Post-transcriptional Program to Promote Melanoma Invasion and Metastasis. Wurth, L, Papasaikas, P, Olmeda, D , Bley, N, Calvo, GT, Guerrero, S, Cerezo-Wallis, D, Martinez-Useros, J, García-Fernández, M, Hüttelmaier, S, Soengas, MS, Gebauer, F. Cancer Cell - 30 (5) : 694-707 (PMID: 27908735) (doi:10.1016/j.ccell.2016.10.004)
27 Oct | 2016 The nuclear corepressor 1 and the thyroid hormone receptor β suppress breast tumor lymphangiogenesis. Martínez-Iglesias, O , Olmeda, D , Alonso-Merino, E , Gómez-Rey, S, González-López, AM, Luengo, E, Soengas, MS, Palacios, J, Regadera, J, Aranda, A . Oncotarget (PMID: 27806339) (doi:10.18632/oncotarget.12978)
2 Oct | 2016 Metastatic risk and resistance to BRAF inhibitors in melanoma defined by selective allelic loss of ATG5. García-Fernández, M, Karras, P, Checinska, A, Cañón, E , Calvo, GT, Gómez-López, G, Cifdaloz, M, Colmenar, A, Espinosa-Hevia, L, Olmeda, D , Soengas, MS. Autophagy - 12 (10) : 1776-1790 (PMID: 27464255) (doi:10.1080/15548627.2016.1199301)
1 Jul | 2016 Vegfr3-CreER (T2) mouse, a new genetic tool for targeting the lymphatic system. Martinez-Corral, I, Stanczuk, L, Frye, M, Ulvmar, MH, Diéguez-Hurtado, R, Olmeda, D , Makinen, T, Ortega, S. Angiogenesis - 19 (3) : 433-445 (PMID: 26993803) (doi:10.1007/s10456-016-9505-x)
1 Jan | 2016 Vesicular trafficking mechanisms in endothelial cells as modulators of the tumor vasculature and targets of antiangiogenic therapies. Maes, H, Olmeda, D , Soengas, MS, Agostinis, P. FEBS J - 283 (1) : 25-38 (PMID: 26443003) (doi:10.1111/febs.13545)
15 Feb | 2015 Zeb1 and Snail1 engage miR-200f transcriptional and epigenetic regulation during EMT. Díaz-López, A, Díaz-Martín, J, Moreno-Bueno, G , Cuevas, EP , Santos, V , Olmeda, D , Portillo, F , Palacios, J, Cano, A . Int. J. Cancer - 136 (4) : E62-73 (PMID: 25178837) (doi:10.1002/ijc.29177)
14 Jul | 2014 RAB7 controls melanoma progression by exploiting a lineage-specific wiring of the endolysosomal pathway. Alonso-Curbelo, D, Riveiro-Falkenbach, E, Pérez-Guijarro, E , Cifdaloz, M, Karras, P, Osterloh, L, Megías, D, Cañón, E , Calvo, TG, Olmeda, D , Gómez-López, G, Graña, O, Sánchez-Arévalo Lobo, VJ, Pisano, DG, Wang, HW, Ortiz-Romero, P, Tormo, D, Hoek, K, Rodríguez-Peralto, JL, Joyce, JA, Soengas, MS. Cancer Cell - 26 (1) : 61-76 (PMID: 24981740) (doi:10.1016/j.ccr.2014.04.030)
10 May | 2012 Blocking ephrinB2 with highly specific antibodies inhibits angiogenesis, lymphangiogenesis, and tumor growth. Abéngozar, MA, de Frutos, S, Ferreiro, S, Soriano, J, Perez-Martinez, M, Olmeda, D , Marenchino, M, Cañamero, M, Ortega, S, Megias, D, Rodriguez, A, Martínez-Torrecuadrada, JL. Blood - 119 (19) : 4565-4576 (PMID: 22446484) (doi:10.1182/blood-2011-09-380006)
17 Apr | 2012 In vivo imaging of lymphatic vessels in development, wound healing, inflammation, and tumor metastasis. Martínez-Corral, I, Olmeda, D , Diéguez-Hurtado, R, Tammela, T, Alitalo, K, Ortega, S. Proc Natl Acad Sci U S A - 109 (16) : 6223-6228 (PMID: 22474390) (doi:10.1073/pnas.1115542109)
3 Jan | 2011 A Cre-reporter transgenic mouse expressing the far-red fluorescent protein Katushka. Diéguez-Hurtado, R, Martín, J, Martínez-Corral, I, Martínez, MD, Megías, D, Olmeda, D , Ortega, S. Genesis - 49 (1) : 36-45 (PMID: 21254335) (doi:10.1002/dvg.20685)
1 Dec | 2010 Hyaluronic acid/chitosan-g-poly(ethylene glycol) nanoparticles for gene therapy: an application for pDNA and siRNA delivery. Raviña, M, Cubillo, E , Olmeda, D , Novoa-Carballal, R, Fernandez-Megia, E, Riguera, R, Sánchez, A, Cano, A , Alonso, MJ. Pharm. Res. - 27 (12) : 2544-2555 (PMID: 20857179) (doi:10.1007/s11095-010-0263-y)
15 Oct | 2009 The morphological and molecular features of the epithelial-to-mesenchymal transition. Moreno-Bueno, G , Peinado, H , Molina, P , Olmeda, D , Cubillo, E , Santos, V , Palacios, J, Portillo, F , Cano, A . Nat Protoc - 4 (11) : 1591-1613 (PMID: 19834475) (doi:10.1038/nprot.2009.152)
7 Aug | 2008 Snai1 and Snai2 collaborate on tumor growth and metastasis properties of mouse skin carcinoma cell lines. Olmeda, D , Montes, A, Moreno-Bueno, G , Flores, JM, Portillo, F , Cano, A . Oncogene - 27 (34) : 4690-4701 (PMID: 18408755) (doi:10.1038/onc.2008.118)
15 Dec | 2007 SNAI1 is required for tumor growth and lymph node metastasis of human breast carcinoma MDA-MB-231 cells. Olmeda, D , Moreno-Bueno, G , Flores, JM, Fabra, A, Portillo, F , Cano, A . Cancer Res. - 67 (24) : 11721-11731 (PMID: 18089802) (doi:10.1158/0008-5472.CAN-07-2318)
1 Jul | 2007 Id-1 is induced in MDCK epithelial cells by activated Erk/MAPK pathway in response to expression of the Snail and E47 transcription factors. Jordà, M, Vinyals, A, Marazuela, A, Cubillo, E , Olmeda, D , Valero, E, Cano, A , Fabra, A. Exp. Cell Res. - 313 (11) : 2389-2403 (PMID: 17490644) (doi:10.1016/j.yexcr.2007.04.001)
27 Jun | 2007 Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? Peinado, H , Olmeda, D , Cano, A . Nat. Rev. Cancer - 7 (6) : 415-428 (PMID: 17508028) (doi:10.1038/nrc2131)
22 Mar | 2007 Snail silencing effectively suppresses tumour growth and invasiveness. Olmeda, D , Jordá, M, Peinado, H , Fabra, A, Cano, A . Oncogene - 26 (13) : 1862-1874 (PMID: 17043660) (doi:10.1038/sj.onc.1209997)
5 Oct | 2005 A molecular role for lysyl oxidase-like 2 enzyme in snail regulation and tumor progression. Peinado, H , Del Carmen Iglesias-de la Cruz, M, Olmeda, D , Csiszar, K, Fong, KS, Vega, S , Nieto, MA, Cano, A , Portillo, F . EMBO J - 24 (19) : 3446-3458 (PMID: 16096638) (doi:10.1038/sj.emboj.7600781)
1 Aug | 2005 Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor. Jordà, M, Olmeda, D , Vinyals, A, Valero, E, Cubillo, E , Llorens, A, Cano, A , Fabra, A. J Cell Sci - 118 (Pt 15) : 3371-3385 (PMID: 16079281) (doi:10.1242/jcs.02465)
15 Sep | 2004 Choline kinase activation is a critical requirement for the proliferation of primary human mammary epithelial cells and breast tumor progression. Ramírez de Molina, A , Báñez-Coronel, M, Gutiérrez, R , Rodríguez-González, A , Olmeda, D , Megías, D, Lacal, JC . Cancer Res. - 64 (18) : 6732-6739 (PMID: 15374991) (doi:10.1158/0008-5472.CAN-04-0489)
14 Jul | 2003 Beta-catenin regulation during the cell cycle: implications in G2/M and apoptosis. Olmeda, D , Castel, S, Vilaró, S, Cano, A . Mol. Biol. Cell - 14 (7) : 2844-2860 (PMID: 12857869) (doi:10.1091/mbc.E03-01-0865)