22 Nov | 2021 PSD-95: An Effective Target for Stroke Therapy Using Neuroprotective Peptides. Ugalde-Triviño, L , Díaz-Guerra, M . Int J Mol Sci - 22 (22) (PMID: 34830481) (doi:10.3390/ijms222212585)
3 May | 2021 A novel cell-penetrating peptide targeting calpain-cleavage of PSD-95 induced by excitotoxicity improves neurological outcome after stroke. Ayuso-Dolado, S , Esteban-Ortega, GM , Vidaurre, ÓG , Díaz-Guerra, M . Theranostics - 11 (14) : 6746-6765 (PMID: 34093851) (doi:10.7150/thno.60701)
1 Feb | 2021 Excitotoxicity-induced endocytosis as a potential target for stroke neuroprotection. Diaz-Guerra, M . Neural Regen Res - 16 (2) : 300-301 (PMID: 32859784) (doi:10.4103/1673-5374.290892)
5 Aug | 2019 Cannabinoid CB2 Receptor Modulation by the Transcription Factor NRF2 is Specific in Microglial Cells. Galán-Ganga, M , Del Río, R , Jiménez-Moreno, N, Díaz-Guerra, M , Lastres-Becker, I . Cell. Mol. Neurobiol. (PMID: 31385133) (doi:10.1007/s10571-019-00719-y)
11 Jul | 2019 Excitotoxic targeting of Kidins220 to the Golgi apparatus precedes calpain cleavage of Rap1-activation complexes. López-Menéndez, C , Simón-García, A , Gamir-Morralla, A , Pose-Utrilla, J , Luján, R, Mochizuki, N, Díaz-Guerra, M , Iglesias, T . Cell Death Dis - 10 (7) : 535 (PMID: 31296845) (doi:10.1038/s41419-019-1766-z)
1 Jul | 2019 Prevention of excitotoxicity-induced processing of BDNF receptor TrkB-FL leads to stroke neuroprotection. Tejeda, GS , Esteban-Ortega, GM , San Antonio, E , Vidaurre, ÓG , Díaz-Guerra, M . EMBO Mol Med - 11 (7) : e9950 (PMID: 31273936) (doi:10.15252/emmm.201809950)
3 Jun | 2019 Prevention of excitotoxicity-induced processing of BDNF receptor TrkB-FL leads to stroke neuroprotection. Tejeda, GS , Esteban-Ortega, GM , San Antonio, E , Vidaurre, ÓG , Díaz-Guerra, M . EMBO Mol Med (PMID: 31160342) (doi:10.15252/emmm.201809950)
28 Jan | 2017 Integral Characterization of Defective BDNF/TrkB Signalling in Neurological and Psychiatric Disorders Leads the Way to New Therapies. Tejeda, GS , Díaz-Guerra, M . Int J Mol Sci - 18 (2) (PMID: 28134845) (doi:10.3390/ijms18020268)
29 Dec | 2015 Brain ischaemia induces shedding of a BDNF-scavenger ectodomain from TrkB receptors by excitotoxicity-activation of metalloproteinases and γ-secretases. Tejeda, GS , Ayuso-Dolado, S , Arbeteta, R, Esteban-Ortega, GM , Vidaurre, OG , Díaz-Guerra, M . J. Pathol. (PMID: 26712630) (doi:10.1002/path.4684)
22 Oct | 2015 Development of a neuroprotective peptide that preserves survival pathways by preventing Kidins220/ARMS calpain processing induced by excitotoxicity. Gamir-Morralla, A , López-Menéndez, C , Ayuso-Dolado, S, Tejeda, GS, Montaner, J, Rosell, A, Iglesias, T , Díaz-Guerra, M . Cell Death Dis - 6 : e1939 (PMID: 26492372) (doi:10.1038/cddis.2015.307)
1 Feb | 2013 Kidins220 accumulates with tau in human Alzheimer's disease and related models: modulation of its calpain-processing by GSK3β/PP1 imbalance. López-Menéndez, C , Gamir-Morralla, A , Jurado-Arjona, J, Higuero, AM , Campanero, MR , Ferrer, I, Hernández, F, Ávila, J, Díaz-Guerra, M , Iglesias, T . Hum. Mol. Genet. - 22 (3) : 466-482 (PMID: 23118350) (doi:10.1093/hmg/dds446)
19 Jan | 2012 Imbalance of neurotrophin receptor isoforms TrkB-FL/TrkB-T1 induces neuronal death in excitotoxicity. Vidaurre, OG, Gascón, S , Deogracias, R, Sobrado, M , Cuadrado, E, Montaner, J, Rodríguez-Peña, A , Díaz-Guerra, M . Cell Death Dis - 3 : e256 (PMID: 22258407) (doi:10.1038/cddis.2011.143)
1 Oct | 2009 Kidins220/ARMS downregulation by excitotoxic activation of NMDARs reveals its involvement in neuronal survival and death pathways. López-Menéndez, C , Gascón, S , Sobrado, M , Vidaurre, OG , Higuero, AM , Rodríguez-Peña, A , Iglesias, T , Díaz-Guerra, M . J. Cell. Sci. - 122 (Pt 19) : 3554-3565 (PMID: 19759287) (doi:10.1242/jcs.056473)
15 Feb | 2008 Dual-promoter lentiviral vectors for constitutive and regulated gene expression in neurons. Gascón, S , Paez-Gomez, JA, Díaz-Guerra, M , Scheiffele, P, Scholl, FG. J. Neurosci. Methods - 168 (1) : 104-112 (PMID: 17983662) (doi:10.1016/j.jneumeth.2007.09.023)
1 Jan | 2008 Excitotoxicity and focal cerebral ischemia induce truncation of the NR2A and NR2B subunits of the NMDA receptor and cleavage of the scaffolding protein PSD-95. Gascón, S , Sobrado, M , Roda, JM, Rodríguez-Peña, A , Díaz-Guerra, M . Mol. Psychiatry - 13 (1) : 99-9114 (PMID: 17486105) (doi:10.1038/sj.mp.4002017)
1 Jun | 2007 Endoplasmic reticulum-associated degradation of the NR1 but not the NR2 subunits of the N-methyl-D-aspartate receptor induced by inhibition of the N-glycosylation in cortical neurons. Gascón, S , García-Gallo, M , Renart, J , Díaz-Guerra, M . J. Neurosci. Res. - 85 (8) : 1713-1723 (PMID: 17455306) (doi:10.1002/jnr.21309)
14 Oct | 2005 Transcription of the NR1 subunit of the N-methyl-D-aspartate receptor is down-regulated by excitotoxic stimulation and cerebral ischemia. Gascón, S , Deogracias, R , Sobrado, M , Roda, JM, Renart, J , Rodríguez-Peña, A , Díaz-Guerra, M . J. Biol. Chem. - 280 (41) : 35018-35027 (PMID: 16049015) (doi:10.1074/jbc.M504108200)
26 Feb | 2002 Characterization of regions in the GP5 protein of porcine reproductive and respiratory syndrome virus required to induce apoptotic cell death. Fernández, A, Suárez, P, Castro, JM, Tabarés, E , Díaz-Guerra, M . Virus Res. - 83 (1-2) : 103-118 (PMID: 11864744)
1 Jun | 2001 The NR1 subunit of the N-methyl-D-aspartate receptor can be efficiently expressed alone in the cell surface of mammalian cells and is required for the transport of the NR2A subunit. García-Gallo, M , Renart, J , Díaz-Guerra, M . Biochem. J. - 356 (Pt 2) : 539-547 (PMID: 11368783)
1 Feb | 1999 Full activation of RNaseL in animal cells requires binding of 2-5A within ankyrin repeats 6 to 9 of this interferon-inducible enzyme. Díaz-Guerra, M , Rivas, C, Esteban, M. J. Interferon Cytokine Res. - 19 (2) : 113-119 (PMID: 10090396) (doi:10.1089/107999099314252)
1 Jan | 1999 Expression of N-methyl-D-aspartate receptors using vaccinia virus causes excitotoxic death in human kidney cells. García-Gallo, M , Behrens, MM, Renart, J , Díaz-Guerra, M . J. Cell. Biochem. - 72 (1) : 135-144 (PMID: 10025674)
10 Apr | 1998 Vaccinia virus E3L protein is an inhibitor of the interferon (i.f.n.)-induced 2-5A synthetase enzyme. Rivas, C, Gil, J, Mĕlková, Z, Esteban, M, Díaz-Guerra, M . Virology - 243 (2) : 406-414 (PMID: 9568039)
29 Sep | 1997 Activation of the IFN-inducible enzyme RNase L causes apoptosis of animal cells. Díaz-Guerra, M , Rivas, C, Esteban, M. Virology - 236 (2) : 354-363 (PMID: 9325243)
1 Apr | 1997 Growth of Escherichia coli in acetate as a sole carbon source is inhibited by ankyrin-like repeats present in the 2',5'-linked oligoadenylate-dependent human RNase L enzyme. Díaz-Guerra, M , Esteban, M, Martínez, JL. FEMS Microbiol. Lett. - 149 (1) : 107-113 (PMID: 9103982)
6 Jan | 1997 Inducible expression of the 2-5A synthetase/RNase L system results in inhibition of vaccinia virus replication. Díaz-Guerra, M , Rivas, C, Esteban, M. Virology - 227 (1) : 220-228 (PMID: 9007077) (doi:10.1006/viro.1996.8294)
1 Sep | 1996 Actin gene structure in two Artemia species, A. franciscana and A. parthenogenetica. Ortega, MA, Díaz-Guerra, M , Sastre, L . J. Mol. Evol. - 43 (3) : 224-235 (PMID: 8703088)
1 May | 1996 Open reading frame 5 of porcine reproductive and respiratory syndrome virus as a cause of virus-induced apoptosis. Suárez, P, Díaz-Guerra, M , Prieto, C, Esteban, M, Castro, JM, Nieto, A, Ortín, J. J. Virol. - 70 (5) : 2876-2882 (PMID: 8627762)
1 Jan | 1994 Structure and expression of a polyubiquitin gene from the crustacean Artemia. Franco, E, Behrens, MM, Díaz-Guerra, M , Renart, J . Gene Expr. - 4 (1-2) : 19-28 (PMID: 7841785)
21 Dec | 1993 Vaccinia virus nucleoside triphosphate phosphohydrolase I controls early and late gene expression by regulating the rate of transcription. Diaz-Guerra, M , Esteban, M. J. Virol. - 67 (12) : 7561-7572 (PMID: 8230476)
22 Nov | 1993 A mutation of the nucleoside triphosphate phosphohydrolase I (NPH-I) gene confers sensitivity of vaccinia virus to interferon. Díaz-Guerra, M , Kahn, JS, Esteban, M. Virology - 197 (1) : 485-491 (PMID: 8212591) (doi:10.1006/viro.1993.1618)
26 Oct | 1992 Aberrant expression of the simple epithelial type II keratin 8 by mouse skin carcinomas but not papillomas. Larcher, F, Bauluz, C, Díaz-Guerra, M , Quintanilla, M , Conti, CJ, Ballestín, C, Jorcano, JL. Mol. Carcinog. - 6 (2) : 112-121 (PMID: 1382441)
1 Feb | 1992 Expression of simple epithelial cytokeratins in mouse epidermal keratinocytes harboring Harvey ras gene alterations. Diaz-Guerra, M , Haddow, S, Bauluz, C, Jorcano, JL, Cano, A , Balmain, A, Quintanilla, M . Cancer Res. - 52 (3) : 680-687 (PMID: 1370649)
11 Aug | 1989 The 5S rRNA-histone repeat in the crustacean Artemia: structure, polymorphism and variation of the 5S rRNA segment in different populations. Cruces, J , Díaz-Guerra, M , Gil, I, Renart, J . Nucleic Acids Res. - 17 (15) : 6283-6297 (PMID: 2570403) (doi:10.1093/nar/17.15.6283)
31 Jul | 1989 Differential expression of a gene highly homologous to c-ras during the development of the brine shrimp Artemia. Díaz-Guerra, M , Quintanilla, M , Palmero, I , Sastre, L , Renart, J . Biochem. Biophys. Res. Commun. - 162 (2) : 802-808 (PMID: 2502981)
1 May | 1986 Satellite DNA in the crustacean Artemia. Cruces, J , Wonenburger, ML, Díaz-Guerra, M , Sebastián, J, Renart, J . Gene - 44 (2-3) : 341-345 (PMID: 3023196)
1 Jan | 1986 Characterization of two types of rRNA gene repeat units from the crustacean Artemia. Gallego, ME, Díaz-Guerra, M , Cruces, J , Sebastián, J, Renart, J . Gene - 48 (1) : 175-182 (PMID: 3557126)