17 jul | 2023 Ferrozoles: Ferrocenyl derivatives of letrozole with dual effects as potent aromatase inhibitors and cytostatic agents. Diaz de Greñu, B, Fernández-Aroca, DM, Organero, JA, Durá, G, Jalón, FA, Sánchez-Prieto, R , Ruiz-Hidalgo, MJ, Rodríguez, AM, Santos, L, Albasanz, JL, Manzano, BR. J Biol Inorg Chem (PMID: 37458856) (doi:10.1007/s00775-023-02006-0)
1 jul | 2023 MAPK11 (p38β) is a major determinant of cellular radiosensitivity by controlling ionizing radiation-associated senescence: An in vitro study. Fernández-Aroca, DM, García-Flores, N, Frost, S, Jiménez-Suárez, J, Rodríguez-González, A, Fernández-Aroca, P, Sabater, S, Andrés, I, Garnés-García, C, Belandia, B , Cimas, FJ, Villar, D, Ruiz-Hidalgo, MJ, Sánchez-Prieto, R . Clin Transl Radiat Oncol - 41 : 100649 (PMID: 37346275) (doi:10.1016/j.ctro.2023.100649)
19 jun | 2023 Etiopathogenic role of ERK5 signaling in sarcoma: prognostic and therapeutic implications. Sánchez-Fdez, A, Matilla-Almazán, S, Del Carmen, S, Abad, M, Arconada-Luque, E, Jiménez-Suárez, J, Chinchilla-Tábora, LM, Ruíz-Hidalgo, MJ, Sánchez-Prieto, R , Pandiella, A, Esparís-Ogando, A. Exp Mol Med (PMID: 37332046) (doi:10.1038/s12276-023-01008-x)
7 mayo | 2023 LDR brachytherapy offers superior tumor control to single-fraction HDR prostate brachytherapy: A prospective study. Jimenez-Garcia, IE, Sabater, S, Martinez-Gutierrez, R, Sanchez-Galiano, P, Berenguer-Serrano, R, Castro-Larefors, S, Rey-Lopez, I, Ruiz-Herrero, B, Sánchez-Prieto, R , Rovirosa, A, Arenas, M, Gonzalez-Suarez, HA. Prostate (PMID: 37150842) (doi:10.1002/pros.24548)
30 ene | 2023 P38 MAPK and Radiotherapy: Foes or Friends? García-Flores, N, Jiménez-Suárez, J, Garnés-García, C, Fernández-Aroca, DM, Sabater, S, Andrés, I, Fernández-Aramburo, A, Ruiz-Hidalgo, MJ, Belandia, B , Sanchez-Prieto, R , Cimas, FJ. Cancers (Basel) - 15 (3) (PMID: 36765819) (doi:10.3390/cancers15030861)
19 jul | 2022 ERK5 Is a Major Determinant of Chemical Sarcomagenesis: Implications in Human Pathology. Arconada-Luque, E, Jiménez-Suarez, J, Pascual-Serra, R, Nam-Cha, SH, Moline, T, Cimas, FJ, Fliquete, G, Ortega-Muelas, M, Roche, O , Fernández-Aroca, DM, Muñoz Velasco, R, García-Flores, N, Garnés-García, C, Sánchez-Fdez, A, Matilla-Almazán, S, Sánchez-Arévalo Lobo, VJ, Hernández-Losa, J, Belandia, B , Pandiella, A, Esparís-Ogando, A, Ramón Y Cajal, S, Del Peso, L , Sánchez-Prieto, R , Ruiz-Hidalgo, MJ. Cancers (Basel) - 14 (14) (PMID: 35884568) (doi:10.3390/cancers14143509)
4 jul | 2022 Keratinocyte-derived S100A9 modulates neutrophil infiltration and affects psoriasis-like skin and joint disease. Mellor, LF, Gago-Lopez, N, Bakiri, L, Schmidt, FN, Busse, B, Rauber, S, Jimenez, M, Megías, D, Oterino-Soto, S, Sanchez-Prieto, R , Grivennikov, S, Pu, X, Oxford, J, Ramming, A, Schett, G, Wagner, EF. Ann Rheum Dis (PMID: 35788494) (doi:10.1136/annrheumdis-2022-222229)
16 oct | 2021 ERK5 signalling pathway is a novel target of sorafenib: Implication in EGF biology. Ortega-Muelas, M, Roche, O , Fernández-Aroca, DM, Encinar, JA, Albandea-Rodríguez, D , Arconada-Luque, E, Pascual-Serra, R, Muñoz, I , Sánchez-Pérez, I , Belandia, B , Ruiz-Hidalgo, MJ, Sánchez-Prieto, R . J Cell Mol Med (PMID: 34655447) (doi:10.1111/jcmm.16990)
9 mar | 2021 Effect of the aniline fragment in Pt(II) and Pt(IV) complexes as anti-proliferative agents. Standard reduction potential as a more reliable parameter for Pt(IV) compounds than peak reduction potential. Leal, J, Santos, L, Fernández-Aroca, DM, Cuevas, JV, Martínez, MA, Massaguer, A, Jalón, FA, Ruiz-Hidalgo, MJ, Sánchez-Prieto, R , Rodríguez, AM, Castañeda, G, Durá, G, Carrión, MC, Barrabés, S, Manzano, BR. J Inorg Biochem - 218 : 111403 (PMID: 33730639) (doi:10.1016/j.jinorgbio.2021.111403)
10 dic | 2020 p38β (MAPK11) mediates gemcitabine-associated radiosensitivity in sarcoma experimental models. Pascual-Serra, R, Fernández-Aroca, DM, Sabater, S, Roche, O, Andrés, I, Ortega-Muelas, M, Arconada-Luque, E, Garcia-Flores, N, Bossi, G, Belandia, B , Ruiz-Hidalgo, MJ, Sánchez-Prieto, R . Radiother Oncol (PMID: 33310004) (doi:10.1016/j.radonc.2020.12.008)
12 oct | 2020 p38β and Cancer: The Beginning of the Road. Roche, O , Fernández-Aroca, DM, Arconada-Luque, E, García-Flores, N, Mellor, LF, Ruiz-Hidalgo, MJ, Sánchez-Prieto, R . Int J Mol Sci - 21 (20) (PMID: 33053909) (doi:10.3390/ijms21207524)
1 sep | 2019 Blockage of autophagic flux is associated with lymphocytosis and higher percentage of tumoral cells in chronic lymphocytic leukemia of B cells. Romero-Macías, JR, Pascual-Serra, R, Roche, O, Ruiz-Marcos, F, Serrano-Martínez, A, González-Aguado, P, Belandia, B , Ruiz-Hidalgo, MJ, Sánchez-Prieto, R . Clin Transl Oncol - 21 (9) : 1280-1285 (PMID: 30680609) (doi:10.1007/s12094-019-02041-x)
1 jun | 2019 P53 pathway is a major determinant in the radiosensitizing effect of Palbociclib: Implication in cancer therapy. Fernández-Aroca, DM, Roche, O, Sabater, S, Pascual-Serra, R, Ortega-Muelas, M, Sánchez Pérez, I , Belandia, B , Ruiz-Hidalgo, MJ, Sánchez-Prieto, R . Cancer Lett. - 451 : 23-33 (PMID: 30872077) (doi:10.1016/j.canlet.2019.02.049)
26 feb | 2019 HIF1α Suppresses Tumor Cell Proliferation through Inhibition of Aspartate Biosynthesis. Meléndez-Rodríguez, F, Urrutia, AA, Lorendeau, D, Rinaldi, G, Roche, O , Böğürcü-Seidel, N, Ortega Muelas, M, Mesa-Ciller, C, Turiel, G, Bouthelier, A, Hernansanz-Agustín, P , Elorza, A, Escasany, E, Li, QOY, Torres-Capelli, M, Tello, D, Fuertes, E, Fraga, E, Martínez-Ruiz, A, Pérez, B, Giménez-Bachs, JM, Salinas-Sánchez, AS, Acker, T, Sánchez Prieto, R , Fendt, SM, De Bock, K, Aragonés, J. Cell Rep - 26 (9) : 2257-2265.e4 (PMID: 30811976) (doi:10.1016/j.celrep.2019.01.106)
26 jul | 2018 Autophagic cell death associated to Sorafenib in renal cell carcinoma is mediated through Akt inhibition in an ERK1/2 independent fashion. Serrano-Oviedo, L, Ortega-Muelas, M, García-Cano, J, Valero, ML, Cimas, FJ, Pascual-Serra, R, Fernandez-Aroca, DM, Roche, O , Ruiz-Hidalgo, MJ, Belandia, B , Giménez-Bachs, JM, Salinas, AS, Sanchez-Prieto, R . PLoS ONE - 13 (7) : e0200878 (PMID: 30048489) (doi:10.1371/journal.pone.0200878)
8 jun | 2018 Hypoxia-Inducible Factor 2-Dependent Pathways Driving Von Hippel-Lindau-Deficient Renal Cancer. Meléndez-Rodríguez, F, Roche, O , Sanchez-Prieto, R , Aragones, J. Front Oncol - 8 : 214 (PMID: 29938199) (doi:10.3389/fonc.2018.00214)
1 dic | 2017 Prognostic Value of the VHL, HIF-1α, and VEGF Signaling Pathway and Associated MAPK (ERK1/2 and ERK5) Pathways in Clear-Cell Renal Cell Carcinoma. A Long-Term Study. Salinas-Sánchez, AS, Serrano-Oviedo, L, Nam-Cha, SY, Roche-Losada, O, Sánchez-Prieto, R , Giménez-Bachs, JM. Clin Genitourin Cancer - 15 (6) : e923-e933 (PMID: 28624320) (doi:10.1016/j.clgc.2017.05.016)
28 jul | 2017 E1a is an exogenous in vivo tumour suppressor. Cimas, FJ, Callejas-Valera, JL, García-Olmo, DC, Hernández-Losa, J, Melgar-Rojas, P, Ruiz-Hidalgo, MJ, Pascual-Serra, R, Ortega-Muelas, M, Roche, O , Marcos, P, Garcia-Gil, E, Fernandez-Aroca, DM, Ramón Y Cajal, S, Gutkind, JS, Sanchez-Prieto, R . Cancer Lett. - 399 : 74-81 (PMID: 28416454) (doi:10.1016/j.canlet.2017.04.010)
6 mar | 2017 VHL promotes immune response against renal cell carcinoma via NF-κB-dependent regulation of VCAM-1. Labrousse-Arias, D, Martínez-Alonso, E, Corral-Escariz, M, Bienes-Martínez, R, Berridy, J, Serrano-Oviedo, L, Conde, E, García-Bermejo, ML, Giménez-Bachs, JM, Salinas-Sánchez, AS, Sánchez-Prieto, R , Yao, M, Lasa, M , Calzada, MJ. J. Cell Biol. - 216 (3) : 835-847 (PMID: 28235946) (doi:10.1083/jcb.201608024)
1 mar | 2017 Implication of VHL, ERK5, and HIF-1alpha in clear cell renal cell carcinoma: Molecular basis. Serrano-Oviedo, L, Giménez-Bachs, JM, Nam-Cha, SY, Cimas, FJ, García-Cano, J, Sánchez-Prieto, R , Salinas-Sánchez, AS. Urol. Oncol. - 35 (3) : 114.e15-114.e22 (PMID: 27836247) (doi:10.1016/j.urolonc.2016.10.010)
1 feb | 2017 KLRC3, a Natural Killer receptor gene, is a key factor involved in glioblastoma tumourigenesis and aggressiveness. Cheray, M, Bessette, B, Lacroix, A, Mélin, C, Jawhari, S, Pinet, S, Deluche, E, Clavère, P, Durand, K, Sanchez-Prieto, R , Jauberteau, MO, Battu, S, Lalloué, F. J. Cell. Mol. Med. - 21 (2) : 244-253 (PMID: 27641066) (doi:10.1111/jcmm.12960)
19 oct | 2016 Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Klionsky, DJ, [ .., ], Bartolomé, A , [ .., ], Escalante, R , [ .., ], Magariños, M , [ .., ], Martín-Sanz, P , [ .., ], Sanchez-Prieto, R , [ .., ], Valverde, AM , [ .., ], Varela-Nieto, I , [ .., ], Zughaier, SM. Autophagy - 12 (1) : 1-222 (PMID: 26799652) (doi:10.1080/15548627.2015.1100356)
30 jun | 2016 p38MAPK and Chemotherapy: We Always Need to Hear Both Sides of the Story. García-Cano, J, Roche, O , Cimas, FJ, Pascual-Serra, R, Ortega-Muelas, M, Fernández-Aroca, DM, Sánchez-Prieto, R . Front Cell Dev Biol - 4 : 69 (PMID: 27446920) (doi:10.3389/fcell.2016.00069)
7 jun | 2016 p75 neurotrophin receptor and pro-BDNF promote cell survival and migration in clear cell renal cell carcinoma. De la Cruz-Morcillo, MA, Berger, J, Sánchez-Prieto, R , Saada, S, Naves, T, Guillaudeau, A, Perraud, A, Sindou, P, Lacroix, A, Descazeaud, A, Lalloué, F, Jauberteau, MO. Oncotarget - 7 (23) : 34480-34497 (PMID: 27120782) (doi:10.18632/oncotarget.8911)
1 jun | 2016 Hepatitis C Virus RNA-Dependent RNA Polymerase Interacts with the Akt/PKB Kinase and Induces Its Subcellular Relocalization. Valero, ML, Sabariegos, R, Cimas, FJ, Perales, C, Domingo, E, Sánchez-Prieto, R , Mas, A. Antimicrob. Agents Chemother. - 60 (6) : 3540-3550 (PMID: 27021315) (doi:10.1128/AAC.03019-15)
1 abr | 2016 Analysing the integration of MR images acquired in a non-radiotherapy treatment position into the radiotherapy workflow using deformable and rigid registration. Sabater, S, Pastor-Juan, Mdel R, Berenguer, R, Andres, I, Sevillano, M, Lozano-Setien, E, Jimenez-Jimenez, E, Rovirosa, A, Sanchez-Prieto, R , Arenas, M. Radiother Oncol - 119 (1) : 179-184 (PMID: 26975240) (doi:10.1016/j.radonc.2016.02.032)
12 feb | 2016 CHK1 expression in Gastric Cancer is modulated by p53 and RB1/E2F1: implications in chemo/radiotherapy response. Bargiela-Iparraguirre, J , Prado-Marchal, L, Fernandez-Fuente, M, Gutierrez-González, A, Moreno-Rubio, J, Muñoz-Fernandez, M, Sereno, M, Sanchez-Prieto, R , Perona, R , Sanchez-Perez, I . Sci Rep - 6 : 21519 (PMID: 26867682) (doi:10.1038/srep21519)
1 feb | 2016 MKP1: Jekyll and Hyde for E1A. Cimas, FJ, Callejas-Valera, JC, Sanchez-Prieto, R . Aging (Albany NY) - 8 (2) : 214-215 (PMID: 26977801) (doi:10.18632/aging.100918)
29 dic | 2015 MKP1 mediates chemosensitizer effects of E1a in response to cisplatin in non-small cell lung carcinoma cells. Cimas, FJ, Callejas-Valera, JL, Pascual-Serra, R, García-Cano, J, Garcia-Gil, E, De la Cruz-Morcillo, MA, Ortega-Muelas, M, Serrano-Oviedo, L, Gutkind, JS, Sánchez-Prieto, R . Oncotarget - 6 (42) : 44095-44107 (PMID: 26689986) (doi:10.18632/oncotarget.6574)
21 nov | 2015 Rectal contrast increases rectal dose during vaginal cuff brachytherapy. Sabater, S, Andres, I, Jimenez-Jimenez, E, Berenguer, R, Sevillano, M, Lopez-Honrubia, V, Rovirosa, A, Sanchez-Prieto, R , Arenas, M. Brachytherapy - 15 (1) : 35-39 (PMID: 26612699) (doi:10.1016/j.brachy.2015.10.005)
1 sep | 2015 DLK1 is a novel inflammatory inhibitor which interferes with NOTCH1 signaling in TLR-activated murine macrophages. González, MJ, Ruiz-García, A, Monsalve, EM, Sánchez-Prieto, R , Laborda, J, Díaz-Guerra, MJ, Ruiz-Hidalgo, MJ. Eur. J. Immunol. - 45 (9) : 2615-2627 (PMID: 26115479) (doi:10.1002/eji.201545514)
20 jun | 2015 Exploiting the potential of autophagy in cisplatin therapy: A new strategy to overcome resistance. García-Cano, J, Ambroise, G, Pascual-Serra, R, Carrión, MC, Serrano-Oviedo, L, Ortega-Muelas, M, Cimas, FJ, Sabater, S, Ruiz-Hidalgo, MJ, Sanchez Perez, I, Mas, A, Jalón, FA, Vazquez, A, Sánchez-Prieto, R . Oncotarget - 6 (17) : 15551-15565 (PMID: 26036632) (doi:10.18632/oncotarget.3902)
4 sep | 2014 E1a promotes c-Myc-dependent replicative stress: implications in glioblastoma radiosensitization. Valero, ML, Cimas, FJ, Arias, L, Melgar-Rojas, P, García, E, Callejas-Valera, JL, García-Cano, J, Serrano-Oviedo, L, de la Cruz-Morcillo, MÁ, Sánchez-Pérez, I , Sánchez-Prieto, R . Cell Cycle - 13 (1) : 52-61 (PMID: 24196438) (doi:10.4161/cc.26754)
10 jul | 2013 Abrogation of the p38 MAPK α signaling pathway does not promote radioresistance but its activity is required for 5-Fluorouracil-associated radiosensitivity. de la Cruz-Morcillo, MA, García-Cano, J, Arias-González, L, García-Gil, E, Artacho-Cordón, F, Ríos-Arrabal, S, Valero, ML, Cimas, FJ, Serrano-Oviedo, L, Villas, MV, Romero-Fernández, J, Núñez, MI, Sánchez-Prieto, R . Cancer Lett. - 335 (1) : 66-74 (PMID: 23403078) (doi:10.1016/j.canlet.2013.01.050)
4 jun | 2013 ERK5/BMK1 is a novel target of the tumor suppressor VHL: implication in clear cell renal carcinoma. Arias-González, L, Moreno-Gimeno, I, del Campo, AR, Serrano-Oviedo, L, Valero, ML, Esparís-Ogando, A, de la Cruz-Morcillo, MÁ, Melgar-Rojas, P, García-Cano, J, Cimas, FJ, Hidalgo, MJ, Prado, A, Callejas-Valera, JL, Nam-Cha, SH, Giménez-Bachs, JM, Salinas-Sánchez, AS, Pandiella, A, del Peso, L , Sánchez-Prieto, R . Neoplasia - 15 (6) : 649-659 (PMID: 23730213)
14 dic | 2012 HIF2α acts as an mTORC1 activator through the amino acid carrier SLC7A5. Elorza, A, Soro-Arnáiz, I, Meléndez-Rodríguez, F, Rodríguez-Vaello, V, Marsboom, G, de Cárcer, G , Acosta-Iborra, B , Albacete-Albacete, L, Ordóñez, A, Serrano-Oviedo, L, Giménez-Bachs, JM, Vara-Vega, A, Salinas, A, Sánchez-Prieto, R , Martín del Río, R, Sánchez-Madrid, F, Malumbres, M, Landázuri, MO, Aragonés, J. Mol. Cell - 48 (5) : 681-691 (PMID: 23103253) (doi:10.1016/j.molcel.2012.09.017)
1 oct | 2012 Carbonic anhydrase IX as a specific biomarker for clear cell renal cell carcinoma: comparative study of Western blot and immunohistochemistry and implications for diagnosis. Giménez-Bachs, JM, Salinas-Sánchez, AS, Serrano-Oviedo, L, Nam-Cha, SH, Rubio-Del Campo, A, Sánchez-Prieto, R . Scand. J. Urol. Nephrol. - 46 (5) : 358-364 (PMID: 22571179) (doi:10.3109/00365599.2012.685493)
1 jul | 2012 Mitogen-activated protein kinase p38 regulates Krox-20 to direct Schwann cell differentiation and peripheral myelination. Hossain, S, de la Cruz-Morcillo, MA, Sanchez-Prieto, R , Almazan, G. Glia - 60 (7) : 1130-1144 (PMID: 22511272) (doi:10.1002/glia.22340)
1 abr | 2012 Guidelines for the use and interpretation of assays for monitoring autophagy. Klionsky, DJ, [ .., ], Calvo-Garrido, J , [ .., ], Escalante, R , [ .., ], Sánchez-Prieto, R , [ .., ], Zuckerbraun, B. Autophagy - 8 (4) : 445-544 (PMID: 22966490)
1 mar | 2012 P38MAPK is a major determinant of the balance between apoptosis and autophagy triggered by 5-fluorouracil: implication in resistance. de la Cruz-Morcillo, MA, Valero, ML, Callejas-Valera, JL, Arias-González, L, Melgar-Rojas, P, Galán-Moya, EM, García-Gil, E, García-Cano, J, Sánchez-Prieto, R . Oncogene - 31 (9) : 1073-1085 (PMID: 21841826) (doi:10.1038/onc.2011.321)
1 feb | 2012 [Role of mitogen-activated protein kinase (MAPK) in the sporadic renal cell carcinoma]. Salinas-Sánchez, AS, Giménez-Bachs, JM, Serrano-Oviedo, L, Nam Cha, S, Sánchez-Prieto, R . Actas Urol Esp - 36 (2) : 99-9103 (PMID: 21959062) (doi:10.1016/j.acuro.2011.07.013)
1 ene | 2012 Autop38-phagy and apop38-tosis in genotoxic stress: a strange duo. Cruz-Morcillo, MA, Sánchez-Prieto, R . Autophagy - 8 (1) : 135-137 (PMID: 22108006) (doi:10.4161/auto.8.1.18275)
2 dic | 2011 Balance between MKK6 and MKK3 mediates p38 MAPK associated resistance to cisplatin in NSCLC. Galan-Moya, EM, de la Cruz-Morcillo, MA, Llanos Valero, M, Callejas-Valera, JL, Melgar-Rojas, P, Hernadez Losa, J, Salcedo, M, Fernández-Aramburo, A, Ramon y Cajal, S, Sánchez-Prieto, R . PLoS ONE - 6 (12) : e28406 (PMID: 22164285) (doi:10.1371/journal.pone.0028406)
1 jul | 2009 ERK2, but not ERK1, mediates acquired and "de novo" resistance to imatinib mesylate: implication for CML therapy. Aceves-Luquero, CI, Agarwal, A, Callejas-Valera, JL, Arias-González, L, Esparís-Ogando, A, del Peso Ovalle, L , Bellón-Echeverria, I, de la Cruz-Morcillo, MA, Galán Moya, EM, Moreno Gimeno, I, Gómez, JC, Deininger, MW, Pandiella, A, Sánchez Prieto, R . PLoS ONE - 4 (7) : e6124 (PMID: 19568437) (doi:10.1371/journal.pone.0006124)
1 ago | 2008 In vitro radiosensitisation by trabectedin in human cancer cell lines. Romero, J, Zapata, I, Córdoba, S, Jimeno, JM, López-Martín, JA, Tercero, JC, De La Torre, A, Vargas, JA, Molerón, R, Sánchez-Prieto, R . Eur. J. Cancer - 44 (12) : 1726-1733 (PMID: 18501589) (doi:10.1016/j.ejca.2008.04.013)
9 mayo | 2008 E1a gene expression blocks the ERK1/2 signaling pathway by promoting nuclear localization and MKP up-regulation: implication in v-H-Ras-induced senescence. Callejas-Valera, JL, Guinea-Viniegra, J, Ramírez-Castillejo, C, Recio, JA, Galan-Moya, E, Martinez, N, Rojas, JM, Ramón y Cajal, S, Sánchez-Prieto, R . J. Biol. Chem. - 283 (19) : 13450-13458 (PMID: 18316372) (doi:10.1074/jbc.M709230200)
15 ene | 2008 c-Abl activates p38 MAPK independently of its tyrosine kinase activity: Implications in cisplatin-based therapy. Galan-Moya, EM, Hernandez-Losa, J, Aceves Luquero, CI, de la Cruz-Morcillo, MA, Ramírez-Castillejo, C, Callejas-Valera, JL, Arriaga, A, Aranburo, AF, Ramón y Cajal, S, Silvio Gutkind, J, Sánchez-Prieto, R . Int. J. Cancer - 122 (2) : 289-297 (PMID: 17893873) (doi:10.1002/ijc.23063)
1 feb | 2007 High prevalence of human papillomavirus 16 in penile carcinoma. Pascual, A , Pariente, M, Godínez, JM, Sánchez-Prieto, R , Atienzar, M, Segura, M, Poblet, E. Histol. Histopathol. - 22 (2) : 177-183 (PMID: 17149690) (doi:10.14670/HH-22.177)
25 ene | 2006 Adenovirus E1A orchestrates the urokinase-plasminogen activator system and upregulates PAI-2 expression, supporting a tumor suppressor effect. Fernández-Soria, V, Lleonart, ME, Diaz-Fuertes, M, Villuendas, R, Sánchez-Prieto, R , Fabra, A, Ramón Y Cajal, S. Int. J. Oncol. - 28 (1) : 143-148 (PMID: 16327990)
1 jun | 2005 The calcium-binding protein calretinin is a marker of the companion cell layer of the human hair follicle. Poblet, E, Jimenez, F, de Cabo, C, Prieto-Martin, A, Sánchez-Prieto, R . Br. J. Dermatol. - 152 (6) : 1316-1320 (PMID: 15948999) (doi:10.1111/j.1365-2133.2005.06603.x)
1 abr | 2005 Modulation of the p38 MAPK (mitogen-activated protein kinase) pathway through Bcr/Abl: implications in the cellular response to Ara-C. Sánchez-Arévalo Lobo, VJ, Aceves Luquero, CI, Alvarez-Vallina, L, Tipping, AJ, Viniegra, JG, Hernández Losa, J, Parada Cobo, C, Galán Moya, EM, Gayoso Cruz, J, Melo, JV, Ramón y Cajal, S, Sánchez-Prieto, R . Biochem. J. - 387 (Pt 1) : 231-238 (PMID: 15540985) (doi:10.1042/BJ20040927)
11 feb | 2005 Full activation of PKB/Akt in response to insulin or ionizing radiation is mediated through ATM. Viniegra, JG, Martínez, N, Modirassari, P, Hernández Losa, J, Parada Cobo, C, Sánchez-Arévalo Lobo, VJ, Aceves Luquero, CI, Alvarez-Vallina, L, Ramón y Cajal, S, Rojas, JM, Sánchez-Prieto, R . J. Biol. Chem. - 280 (6) : 4029-4036 (PMID: 15546863) (doi:10.1074/jbc.M410344200)
26 jun | 2003 Role of the p38 MAPK pathway in cisplatin-based therapy. Hernández Losa, J, Parada Cobo, C, Guinea Viniegra, J, Sánchez-Arevalo Lobo, VJ, Ramón y Cajal, S, Sánchez-Prieto, R . Oncogene - 22 (26) : 3998-4006 (PMID: 12821934) (doi:10.1038/sj.onc.1206608)
1 feb | 2003 Adenovirus E1a protein enhances the cytotoxic effects of the herpes thymidine kinase-ganciclovir system. Parada, C, Hernández Losa, J, Guinea, J, Sánchez-Arévalo, V, Fernández Soria, V, Alvarez-Vallina, L, Sánchez-Prieto, R , Ramón y Cajal, S. Cancer Gene Ther. - 10 (2) : 152-160 (PMID: 12536204) (doi:10.1038/sj.cgt.7700550)
27 ene | 2003 JC virus and human colon carcinoma: an intriguing and inconclusive association. Hernández Losa, J, Fernandez-Soria, V, Parada, C, Sanchez-Prieto, R , Ramón Y Cajal, S, Fedele, CG, Tenorio, A. Gastroenterology - 124 (1) : 268-9; author reply 269-70 (PMID: 12512060) (doi:10.1053/gast.2003.50033)
8 ene | 2003 Inconclusive presence of adenovirus sequences in human leukemias and lymphomas. Fernandez-Soria, V, Bornstein, R, Forteza, J, Parada, C, Sanchez-Prieto, R , Ramón y Cajal, S. Oncol. Rep. - 9 (4) : 897-902 (PMID: 12066228)
10 oct | 2002 Modulation of PI3K/Akt pathway by E1a mediates sensitivity to cisplatin. Guinea Viniegra, J, Hernández Losa, J, Sánchez-Arévalo, VJ, Parada Cobo, C, Fernández Soria, VM, Ramón y Cajal, S, Sánchez-Prieto, R . Oncogene - 21 (46) : 7131-7136 (PMID: 12370836) (doi:10.1038/sj.onc.1205934)
31 ene | 2002 Regulation of p73 by c-Abl through the p38 MAP kinase pathway. Sanchez-Prieto, R , Sanchez-Arevalo, VJ, Servitja, JM, Gutkind, JS. Oncogene - 21 (6) : 974-979 (PMID: 11840343) (doi:10.1038/sj.onc.1205134)
1 nov | 2001 Intravascular injections of a conditional replicative adenovirus (adl118) prevent metastatic disease in human breast carcinoma xenografts. Fabra, A, Parada, C, Vinyals, A, Martín Duque, P, Fernandez, V, Sanchez-Prieto, R , Ramon y Cajal, S. Gene Ther. - 8 (21) : 1627-1634 (PMID: 11895001) (doi:10.1038/sj.gt.3301567)
1 jun | 2001 Selective effects of E1B-defective adenoviruses and adenovirus E1A mutants in deficient mouse primary embryonic fibroblasts. Martin Duque, P, Parada, C, Guinea, J, Sanchez-Prieto, R , Ramon Y Cajal, S. Int. J. Oncol. - 18 (6) : 1163-1167 (PMID: 11351246)
1 jul | 2000 Tumor heterogeneity: morphological, molecular and clinical implications. Lleonart, ME, Martin-Duque, P , Sanchez-Prieto, R , Moreno, A, Ramon y Cajal, S. Histol. Histopathol. - 15 (3) : 881-898 (PMID: 10963132) (doi:10.14670/HH-15.881)
1 mayo | 2000 A role for the p38 mitogen-acitvated protein kinase pathway in the transcriptional activation of p53 on genotoxic stress by chemotherapeutic agents. Sanchez-Prieto, R , Rojas, JM, Taya, Y, Gutkind, JS. Cancer Res. - 60 (9) : 2464-2472 (PMID: 10811125)
6 ene | 2000 Adenovirus lacking the 19-kDa and 55-kDa E1B genes exerts a marked cytotoxic effect in human malignant cells. Duque, PM, Alonso, C, Sánchez-Prieto, R , Lleonart, M, Martínez, C, de Buitrago, GG, Cano, A , Quintanilla, M , Ramon y Cajal, S. Cancer Gene Ther. - 6 (6) : 554-563 (PMID: 10608352) (doi:10.1038/sj.cgt.7700077)
1 ene | 2000 Adenovirus E1A and Ewing tumors. de Alava, E, Sanchez-Prieto, R , Ramon Y Cajal, S. Nat. Med. - 6 (1) : 4 (PMID: 10613795) (doi:10.1038/71515)
27 dic | 1999 In vivo radiosensitizing effect of the adenovirus E1A gene in murine and human malignant tumors. Martin-Duque, P , Sánchez-Prieto, R , Romero, J, Martinez-Lamparero, A , Cebrian-Sagarriga, S, Guinea-Viniegra, J, Dominguez, C, Lleonart, M, Cano, A , Quintanilla, M , Ramón Y Cajal, S. Int. J. Oncol. - 15 (6) : 1163-1168 (PMID: 10568823)
24 sep | 1999 An association between viral genes and human oncogenic alterations: the adenovirus E1A induces the Ewing tumor fusion transcript EWS-FLI1. Sanchez-Prieto, R , de Alava, E, Palomino, T , Guinea, J, Fernandez, V, Cebrian, S, LLeonart, M, Cabello, P, Martin, P, San Roman, C, Bornstein, R, Pardo, J, Martinez, A, Diaz-Espada, F, Barrios, Y, Ramon y Cajal, S. Nat. Med. - 5 (9) : 1076-1079 (PMID: 10470089) (doi:10.1038/12516)
19 oct | 1998 In vivo antitumor effect of retrovirus-mediated gene transfer of the adenovirus E1a gene. Sánchez-Prieto, R , Quintanilla, M , Martín, P, Lleonart, M, Cano, A , Dotto, GP, Ramón y Cajal, S. Cancer Gene Ther. - 5 (4) : 215-224 (PMID: 9694073)
1 sep | 1998 Microsatellite instability and p53 mutations in sporadic right and left colon carcinoma: different clinical and molecular implications. Lleonart, ME, García-Foncillas, J, Sánchez-Prieto, R , Martín, P, Moreno, A, Salas, C, Ramón y Cajal, S. Cancer - 83 (5) : 889-895 (PMID: 9731891)
1 jun | 1998 Antitumor effect of E1B defective adenoviruses in human malignant cells. Martín Duque, P, Alonso, C, Sánchez-Prieto, R , Lleonart, M, Ramón y Cajal, S. Adv. Exp. Med. Biol. - 451 : 87-89 (PMID: 10026855)
1 mayo | 1998 In vivo tumor suppressor effect of retrovirus-mediated gene transfer of the adenovirus E1a gene. Sanchez-Prieto, R , Quintanilla, M , Cano, A , Lleonart, M, Martin, P, Ramon y Cajal, S. Adv. Exp. Med. Biol. - 451 : 79-86 (PMID: 10026854)
1 feb | 1998 Antitumoral effect of E1B defective adenoviruses in human malignant cells. Duque, PM, Alonso, C, Sanchez-Prieto, R , Quintanilla, M , Ramón, S, Ramon y Cajal, S. Gene Ther. - 5 (2) : 286-287 (PMID: 9578851) (doi:10.1038/sj.gt.3300585)
1 ene | 1998 Perspectives in gene therapy. Martin Duque, MP, Sánchez-Prieto, R , Lleonart, M, Ramón y Cajal, S. Histol. Histopathol. - 13 (1) : 231-242 (PMID: 9476652)
5 sep | 1996 Carcinoma cell lines become sensitive to DNA-damaging agents by the expression of the adenovirus E1A gene. Sánchez-Prieto, R , Quintanilla, M , Cano, A , Leonart, ML, Martin, P, Anaya, A, Ramón y Cajal, S. Oncogene - 13 (5) : 1083-1092 (PMID: 8806698)
1 oct | 1995 A genetic model for undifferentiated cell tumor formation: similar tumors formed by different cell lines transformed by the E1A oncogene. Ramón y Cajal, S, Sánchez-Prieto, R , Anaya, A. Histol. Histopathol. - 10 (4) : 811-820 (PMID: 8574001)
17 ago | 1995 Lack of correlation between p53 protein level and sensitivity of DNA-damaging agents in keratinocytes carrying adenovirus E1a mutants. Sanchez-Prieto, R , Lleonart, M, Ramón y Cajal, S. Oncogene - 11 (4) : 675-682 (PMID: 7651731)