16 Jan | 2025 The PKA signaling pathway regulates the association of the autophagy initiation complex with the lipidation machinery. Bueno-Arribas, M , Cruz-Cuevas, C , Monforte-Martinez, B , Navas, MA , Escalante, R , Vincent, O . J Mol Biol (PMID: 39826713) (doi:10.1016/j.jmb.2025.168954)
2 Jul | 2024 Methods to Assess Autophagic Activity in Dictyostelium. Antón-Esteban, L , Tornero-Écija, A , Vincent, O , Escalante, R . Methods Mol Biol - 2814 : 97-9106 (PMID: 38954200) (doi:10.1007/978-1-0716-3894-1_7)
22 Nov | 2023 Coiled-coil-mediated dimerization of Atg16 is required for binding to the PROPPIN Atg21. Bueno-Arribas, M , Cruz-Cuevas, C , Navas, MA , Escalante, R , Vincent, O . Open Biol - 13 (11) : 230192 (PMID: 37989223) (doi:10.1098/rsob.230192)
1 Jun | 2023 The association of lipid transfer protein VPS13A with endosomes is mediated by sorting nexin SNX5. Tornero-Écija, A , Zapata-Del-Baño, A , Antón-Esteban, L , Vincent, O , Escalante, R . Life Sci Alliance - 6 (6) (PMID: 36977596) (doi:10.26508/lsa.202201852)
10 May | 2023 Effect of rapamycin on lysosomal accumulation in a CRISPR/Cas9-based cellular model of VPS13A deficiency. Tornero-Écija, AR , Navas, MA , Muñoz-Braceras, S , Vincent, O , Escalante, R . J Cell Mol Med (PMID: 37163371) (doi:10.1111/jcmm.17768)
1 Sep | 2021 The WIPI Gene Family and Neurodegenerative Diseases: Insights From Yeast and Dictyostelium Models. Vincent, O , Antón-Esteban, L , Bueno-Arribas, M , Tornero-Écija, A , Navas, MÁ, Escalante, R . Front Cell Dev Biol - 9 : 737071 (PMID: 34540850) (doi:10.3389/fcell.2021.737071)
9 Aug | 2021 A conserved ATG2 binding site in WIPI4 and yeast Hsv2 is disrupted by mutations causing β-propeller protein-associated neurodegeneration. Bueno-Arribas, M , Blanca, I, Cruz-Cuevas, C , Escalante, R , Navas, MA , Vincent, O . Hum Mol Genet (PMID: 34368840) (doi:10.1093/hmg/ddab225)
27 Jul | 2021 A Dictyostelium model for BPAN disease reveals a functional relationship between the WDR45/WIPI4 homolog Wdr45l and Vmp1 in the regulation of autophagy-associated PtdIns3P and ER stress. Tornero-Écija, A , Tábara, LC , Bueno-Arribas, M , Antón-Esteban, L , Navarro-Gómez, C , Sánchez, I , Vincent, O , Escalante, R . Autophagy (PMID: 34328055) (doi:10.1080/15548627.2021.1953262)
8 Feb | 2021 Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Klionsky, DJ, [ .., ], Bartolome, A , [ .., ], Cuadrado, A , [ .., ], Escalante, R , [ .., ], García-Sanz, P , [ .., ], Lastres-Becker, I , [ .., ], León, Y , [ .., ], Martin-Sanz, P , [ .., ], Pajares, M , [ .., ], Rojo, AI , [ .., ], Valverde, AM , [ .., ], Varela-Nieto, I , [ .., ], Villalobo, A , [ .., ], Vincent, O , [ .., ], Tong, CK. Autophagy (PMID: 33634751) (doi:10.1080/15548627.2020.1797280)
3 Dec | 2020 A novel reverse two-hybrid method for the identification of missense mutations that disrupt protein-protein binding. Vincent, O , Gutierrez-Nogués, A, Trejo-Herrero, A, Navas, MA . Sci Rep - 10 (1) : 21043 (PMID: 33273586) (doi:10.1038/s41598-020-77992-1)
12 Dec | 2019 Evidence for an evolutionary relationship between Vmp1 and bacterial DedA proteins. Tábara, LC , Vincent, O , Escalante, R . Int. J. Dev. Biol. - 63 (1-2) : 67-71 (PMID: 30785211) (doi:10.1387/ijdb.180312re)
22 Feb | 2019 VPS13A is closely associated with mitochondria and is required for efficient lysosomal degradation. Muñoz-Braceras, S , Tornero-Écija, AR , Vincent, O , Escalante, R . Dis Model Mech - 12 (2) (PMID: 30709847) (doi:10.1242/dmm.036681)
1 Aug | 2018 Vacuole membrane protein 1 marks endoplasmic reticulum subdomains enriched in phospholipid synthesizing enzymes and is required for phosphoinositide distribution. Tábara, LC , Vicente, JJ, Biazik, J, Eskelinen, EL, Vincent, O , Escalante, R . Traffic - 19 (8) : 624-638 (PMID: 29761602) (doi:10.1111/tra.12581)
1 Jul | 2018 Functional characterization of MODY2 mutations in the nuclear export signal of glucokinase. Gutierrez-Nogués, A, García-Herrero, CM, Oriola, J, Vincent, O , Navas, MA . Biochim. Biophys. Acta - 1864 (7) : 2385-2394 (PMID: 29704611) (doi:10.1016/j.bbadis.2018.04.020)
10 Jun | 2018 Unfolding the Endoplasmic Reticulum of a Social Amoeba: Dictyostelium discoideum as a New Model for the Study of Endoplasmic Reticulum Stress. Domínguez-Martín, E , Hernández-Elvira, M, Vincent, O , Coria, R, Escalante, R . Cells - 7 (6) (PMID: 29890774) (doi:10.3390/cells7060056)
9 Apr | 2018 IreA controls endoplasmic reticulum stress-induced autophagy and survival through homeostasis recovery. Domínguez-Martín, E , Ongay-Larios, L, Kawasaki, L, Vincent, O , Coello, G, Coria, R, Escalante, R . Mol. Cell. Biol. (PMID: 29632077) (doi:10.1128/MCB.00054-18)
2 Jan | 2017 Autophagy in Dictyostelium: Mechanisms, regulation and disease in a simple biomedical model. Mesquita, A , Cardenal-Muñoz, E, Dominguez, E , Muñoz-Braceras, S , Nuñez-Corcuera, B, Phillips, BA, Tábara, LC, Xiong, Q, Coria, R, Eichinger, L, Golstein, P, King, JS, Soldati, T, Vincent, O , Escalante, R . Autophagy - 13 (1) : 24-40 (PMID: 27715405) (doi:10.1080/15548627.2016.1226737)
6 Aug | 2015 Dissecting the function of Atg1 complex in Dictyostelium autophagy reveals a connection with the pentose phosphate pathway enzyme transketolase. Mesquita, A , Tábara, LC, Martinez-Costa, O , Santos-Rodrigo, N , Vincent, O , Escalante, R . Open Biol - 5 (8) (PMID: 26246495) (doi:10.1098/rsob.150088)
7 Apr | 2015 Casein kinase 1 controls the activation threshold of an α-arrestin by multisite phosphorylation of the interdomain hinge. Herrador, A , Livas, D , Soletto, L, Becuwe, M, Léon, S, Vincent, O . Mol. Biol. Cell (PMID: 25851600) (doi:10.1091/mbc.E14-11-1552)
10 Feb | 2015 Lack of glibenclamide response in a case of permanent neonatal diabetes caused by incomplete inactivation of glucokinase. Oriola, J, Moreno, F, Gutiérrez-Nogués, A, León, S, García-Herrero, CM, Vincent, O , Navas, MA . JIMD Rep - 20 : 21-26 (PMID: 25665835) (doi:10.1007/8904_2014_383)
7 Jun | 2013 A mechanism for protein monoubiquitination dependent on a trans-acting ubiquitin-binding domain. Herrador, A , Léon, S, Haguenauer-Tsapis, R, Vincent, O . J. Biol. Chem. - 288 (23) : 16206-16211 (PMID: 23645667) (doi:10.1074/jbc.C113.452250)
4 Sep | 2012 Ubiquitin-mediated regulation of endocytosis by proteins of the arrestin family. Becuwe, M, Herrador, A , Haguenauer-Tsapis, R, Vincent, O , Léon, S. Biochem Res Int - 2012 : 242764 (PMID: 22988512) (doi:10.1155/2012/242764)
28 Feb | 2012 EhADH112 is a Bro1 domain-containing protein involved in the Entamoeba histolytica multivesicular bodies pathway. Bañuelos, C, García-Rivera, G, López-Reyes, I, Mendoza, L, González-Robles, A, Herranz, S, Vincent, O , Orozco, E. J. Biomed. Biotechnol. - 2012 : 657942 (PMID: 22500103) (doi:10.1155/2012/657942)
24 Jan | 2012 Functional characterization of MODY2 mutations highlights the importance of the fine-tuning of glucokinase and its role in glucose sensing. García-Herrero, CM, Rubio-Cabezas, O, Azriel, S, Gutierrez-Nogués, A, Aragonés, A, Vincent, O , Campos-Barros, A, Argente, J, Navas, MA . PLoS ONE - 7 (1) : e30518 (PMID: 22291974) (doi:10.1371/journal.pone.0030518)
23 Jan | 2012 A molecular switch on an arrestin-like protein relays glucose signaling to transporter endocytosis. Becuwe, M, Vieira, N, Lara, D , Gomes-Rezende, J, Soares-Cunha, C, Casal, M, Haguenauer-Tsapis, R, Vincent, O , Paiva, S, Léon, S. J. Cell Biol. - 196 (2) : 247-259 (PMID: 22249293) (doi:10.1083/jcb.201109113)
17 May | 2010 Detection of the Endosomal Sorting Complex Required for Transport in Entamoeba histolytica and Characterization of the EhVps4 Protein. López-Reyes, I, García-Rivera, G, Bañuelos, C, Herranz, S, Vincent, O , López-Camarillo, C, Marchat, LA, Orozco, E. J. Biomed. Biotechnol. - 2010 : 890674 (PMID: 20508821) (doi:10.1155/2010/890674)
12 Feb | 2010 Recruitment of the ESCRT machinery to a putative seven-transmembrane-domain receptor is mediated by an arrestin-related protein. Herrador, A , Herranz, S, Lara, D , Vincent, O . Mol. Cell. Biol. - 30 (4) : 897-907 (PMID: 20028738) (doi:10.1128/MCB.00132-09)
1 Oct | 2007 PalC, one of two Bro1 domain proteins in the fungal pH signalling pathway, localizes to cortical structures and binds Vps32. Galindo, A, Hervás-Aguilar, A, Rodríguez-Galán, O, Vincent, O , Arst, HN, Tilburn, J, Peñalva, MA. Traffic - 8 (10) : 1346-1364 (PMID: 17696968) (doi:10.1111/j.1600-0854.2007.00620.x)
1 Feb | 2007 Functional analysis of human glucokinase gene mutations causing MODY2: exploring the regulatory mechanisms of glucokinase activity. García-Herrero, CM, Galán, M, Vincent, O , Flández, B, Gargallo, M, Delgado-Alvarez, E, Blázquez, E, Navas, MA . Diabetologia - 50 (2) : 325-333 (PMID: 17186219) (doi:10.1007/s00125-006-0542-7)
1 Apr | 2006 Gene symbol: GCK. Disease: diabetes, MODY. Navas, MA , Galan, M, Vincent, O , Roncero, I, Azriel, S, Boix-Pallares, P, Delgado-Alvarez, E, Diaz-Cadórniga, F, Blázquez, E. Hum. Genet. - 119 (3) : 363 (PMID: 17230658)
1 Jan | 2006 Effects of novel maturity-onset diabetes of the young (MODY)-associated mutations on glucokinase activity and protein stability. Galán, M, Vincent, O , Roncero, I, Azriel, S, Boix-Pallares, P, Delgado-Alvarez, E, Díaz-Cadórniga, F, Blázquez, E, Navas, MA . Biochem J - 393 (Pt 1) : 389-396 (PMID: 16173921) (doi:10.1042/BJ20051137)
9 Dec | 2005 Functions of early (AP-2) and late (AIP1/ALIX) endocytic proteins in equine infectious anemia virus budding. Chen, C, Vincent, O , Jin, J, Weisz, OA, Montelaro, RC. J. Biol. Chem. - 280 (49) : 40474-40480 (PMID: 16215227) (doi:10.1074/jbc.M509317200)
23 Aug | 2005 Arrestin-related proteins mediate pH signaling in fungi. Herranz, S, Rodríguez, JM, Bussink, HJ, Sánchez-Ferrero, JC, Arst, HN, Peñalva, MA, Vincent, O . Proc Natl Acad Sci U S A - 102 (34) : 12141-12146 (PMID: 16099830) (doi:10.1073/pnas.0504776102)
1 Mar | 2003 YPXL/I is a protein interaction motif recognized by aspergillus PalA and its human homologue, AIP1/Alix. Vincent, O , Rainbow, L, Tilburn, J, Arst, HN, Peñalva, MA. Mol. Cell. Biol. - 23 (5) : 1647-1655 (PMID: 12588984)
1 Oct | 2001 Regulatory elements in the FBP1 promoter respond differently to glucose-dependent signals in Saccharomyces cerevisiae. Zaragoza, O , Vincent, O , Gancedo, JM . Biochem. J. - 359 (Pt 1) : 193-201 (PMID: 11563983)
20 Sep | 2001 Interaction of the Srb10 kinase with Sip4, a transcriptional activator of gluconeogenic genes in Saccharomyces cerevisiae. Vincent, O , Kuchin, S, Hong, SP, Townley, R, Vyas, VK, Carlson, M. Mol. Cell. Biol. - 21 (17) : 5790-5796 (PMID: 11486018)
1 May | 2001 Subcellular localization of the Snf1 kinase is regulated by specific beta subunits and a novel glucose signaling mechanism. Vincent, O , Townley, R, Kuchin, S, Carlson, M. Genes Dev. - 15 (9) : 1104-1114 (PMID: 11331606) (doi:10.1101/gad.879301)
1 Oct | 2000 Mitochondrial respiratory mutants of Saccharomyces cerevisiae accumulate glycogen and readily mobilize it in a glucose-depleted medium. Enjalbert, B, Parrou, JL, Vincent, O , François, J. Microbiology (Reading, Engl.) - 146 ( Pt 10) : 2685-2694 (PMID: 11021944)
1 Dec | 1999 Gal83 mediates the interaction of the Snf1 kinase complex with the transcription activator Sip4. Vincent, O , Carlson, M. EMBO J. - 18 (23) : 6672-6681 (PMID: 10581241) (doi:10.1093/emboj/18.23.6672)
1 Dec | 1998 Sip4, a Snf1 kinase-dependent transcriptional activator, binds to the carbon source-responsive element of gluconeogenic genes. Vincent, O , Carlson, M. EMBO J. - 17 (23) : 7002-7008 (PMID: 9843506) (doi:10.1093/emboj/17.23.7002)
26 May | 1995 Analysis of positive elements sensitive to glucose in the promoter of the FBP1 gene from yeast. Vincent, O , Gancedo, JM . J. Biol. Chem. - 270 (21) : 12832-12838 (PMID: 7759539)
1 Mar | 1995 Expression of a yeast gene can be blocked by insertion of short yeast DNA fragments between a UAS and the TATA box. Vincent, O , Gancedo, JM . Curr. Genet. - 27 (4) : 387-389 (PMID: 7614563)
7 Oct | 1991 Regions in the promoter of the yeast FBP1 gene implicated in catabolite repression may bind the product of the regulatory gene MIG1. Mercado, JJ, Vincent, O , Gancedo, JM . FEBS Lett. - 291 (1) : 97-9100 (PMID: 1657641)