1 Dec | 2023 The thyroid hormone enhances mouse embryonic fibroblasts reprogramming to pluripotent stem cells: role of the nuclear receptor corepressor 1. Contreras-Jurado, C , Montero-Pedrazuela, A , Pérez, RF, Alemany, S , Fraga, MF, Aranda, A . Front Endocrinol (Lausanne) - 14 : 1235614 (PMID: 38107517) (doi:10.3389/fendo.2023.1235614)
9 Nov | 2022 Free triiodothyronine levels and age influences the metabolic profile and COVID-19 severity parameters in euthyroid and levothyroxine-treated patients. Amich, I, Anguita, E, Escribano-Serrat, S, Alvarez, C, Rodríguez-Muñoz, D , García, V, Bello, R, Peña-Pedrosa, JA, Martínez-Micaelo, N, Amigó, N, Ortiz, P, Torrejón, MJ, Boscá, L , Martín-Sánchez, J, Aranda, A , Alemany, S . Front Endocrinol (Lausanne) - 13 : 1025032 (PMID: 36440226) (doi:10.3389/fendo.2022.1025032)
22 Jul | 2022 Regulation of metabolic and transcriptional responses by the thyroid hormone in cellular models of murine macrophages. López-Mateo, I , Rodríguez-Muñoz, D , de La Rosa, JV, Castrillo, A , Alemany, S , Aranda, A . Front Immunol - 13 : 923727 (PMID: 35935955) (doi:10.3389/fimmu.2022.923727)
8 Apr | 2022 Hypothyroidism confers tolerance to cerebral malaria. Rodriguez-Muñoz, D , Sánchez, Á , Pérez-Benavente, S, Contreras-Jurado, C , Montero-Pedrazuela, A , Toledo-Castillo, M , Gutiérrez-Hernández, M , Rodrigues-Díez, R, Folgueira, C, Briones, AM, Sabio, G, Monedero-Cobeta, I, Chávez-Coira, I, Castejón, D, Fernández-Valle, E, Regadera, J, Bautista, JM, Aranda, A , Alemany, S . Sci Adv - 8 (14) : eabj7110 (PMID: 35385300) (doi:10.1126/sciadv.abj7110)
27 Jan | 2021 MicroRNAs and thyroid hormone action. Aranda, A . Mol Cell Endocrinol (PMID: 33515639) (doi:10.1016/j.mce.2021.111175)
9 Dec | 2020 Nuclear receptors: lipid and hormone sensors with essential roles in the control of cancer development. Font-Díaz, J, Jiménez-Panizo, A, Caelles, C, Vivanco, MD, Pérez, P, Aranda, A , Estébanez-Perpiñá, E, Castrillo, A , Ricote, M, Valledor, AF. Semin Cancer Biol (PMID: 33309851) (doi:10.1016/j.semcancer.2020.12.007)
28 Oct | 2020 Stress erythropoiesis in atherogenic mice. Sánchez, Á , Orizaola, MC , Rodríguez-Muñoz, D , Aranda, A , Castrillo, A , Alemany, S . Sci Rep - 10 (1) : 18469 (PMID: 33116141) (doi:10.1038/s41598-020-74665-x)
1 Jan | 2020 Hematopoiesis in aged female mice devoid of thyroid hormone receptors. Sánchez, Á , Contreras-Jurado, C , Rodríguez, D , Regadera, J, Alemany, S , Aranda, A . J. Endocrinol. - 244 (1) : 83-94 (PMID: 31585438) (doi:10.1530/JOE-19-0339)
23 Nov | 2019 The thyroid hormone receptor β inhibits self-renewal capacity of breast cancer stem cells. López-Mateo, I , Alonso-Merino, E , Suárez-Cabrera, C, Park, JW, Cheng, SY, Alemany, S , Paramio, JM, Aranda, A . Thyroid (PMID: 31760908) (doi:10.1089/thy.2019.0175)
1 Jul | 2019 Early induction of senescence and immortalization in PGC-1α-deficient mouse embryonic fibroblasts. Prieto, I , Zambrano, A , Laso, J, Aranda, A , Samper, E, Monsalve, M . Free Radic. Biol. Med. - 138 : 23-32 (PMID: 31029787) (doi:10.1016/j.freeradbiomed.2019.04.015)
10 May | 2018 The thyroid hormone receptors regulate the expression of microRNAs with key roles in skin homeostasis. Ruiz-Llorente, L , Contreras-Jurado, C , Martínez-Fernández, M, Paramio, JM, Aranda, A . Thyroid (PMID: 29742977) (doi:10.1089/thy.2017.0369)
10 Jul | 2017 Map3k8 controls granulocyte colony-stimulating factor production and neutrophil precursor proliferation in lipopolysaccharide-induced emergency granulopoiesis. Sánchez, Á , Relaño, C , Carrasco, A , Contreras-Jurado, C , Martín-Duce, A, Aranda, A , Alemany, S . Sci Rep - 7 (1) : 5010 (PMID: 28694430) (doi:10.1038/s41598-017-04538-3)
13 Apr | 2017 Pro-apoptotic signaling induced by Retinoic acid and dsRNA is under the control of Interferon Regulatory Factor-3 in breast cancer cells. Bernardo, AR, Cosgaya, JM , Aranda, A , Jiménez-Lara, AM . Apoptosis (PMID: 28409399) (doi:10.1007/s10495-017-1377-z)
1 Feb | 2017 Map3k8 Modulates Monocyte State and Atherogenesis in ApoE-/- Mice. Sanz-Garcia, C, Sánchez, Á , Contreras-Jurado, C , Cales, C, Barranquero, C, Muñoz, M, Merino, R, Escudero, P, Sanz, MJ, Osada, J, Aranda, A , Alemany, S . Arterioscler. Thromb. Vasc. Biol. - 37 (2) : 237-246 (PMID: 27856455) (doi:10.1161/ATVBAHA.116.308528)
27 Oct | 2016 The nuclear corepressor 1 and the thyroid hormone receptor β suppress breast tumor lymphangiogenesis. Martínez-Iglesias, O , Olmeda, D , Alonso-Merino, E , Gómez-Rey, S, González-López, AM, Luengo, E, Soengas, MS, Palacios, J, Regadera, J, Aranda, A . Oncotarget (PMID: 27806339) (doi:10.18632/oncotarget.12978)
3 Aug | 2016 The Thyroid Hormone Receptors Inhibit Hepatic Interleukin-6 Signaling During Endotoxemia. Contreras-Jurado, C , Alonso-Merino, E , Saiz-Ladera, C, Valiño, AJ, Regadera, J, Alemany, S , Aranda, A . Sci Rep - 6 : 30990 (PMID: 27484112) (doi:10.1038/srep30990)
14 Jun | 2016 Thyroid hormones inhibit TGF-β signaling and attenuate fibrotic responses. Alonso-Merino, E , Martín Orozco, R, Ruíz-Llorente, L, Martínez-Iglesias, OA, Velasco-Martín, JP, Montero-Pedrazuela, A , Fanjul-Rodríguez, L, Contreras-Jurado, C , Regadera, J, Aranda, A . Proc. Natl. Acad. Sci. U.S.A. - 113 (24) : E3451-60 (PMID: 27247403) (doi:10.1073/pnas.1506113113)
2 May | 2016 Tumor suppressive actions of the nuclear receptor corepressor 1. Martínez-Iglesias, O , Alonso-Merino, E , Aranda, A . Pharmacol. Res. - 108 : 75-79 (PMID: 27149915) (doi:10.1016/j.phrs.2016.04.027)
19 Jan | 2016 Autoregulatory loop of nuclear corepressor 1 expression controls invasion, tumor growth, and metastasis. Martínez-Iglesias, OA, Alonso-Merino, E , Gómez-Rey, S, Velasco-Martín, JP, Martín Orozco, R, Luengo, E, García Martín, R, Ibáñez de Cáceres, I, Fernández, AF, Fraga, MF, González-Peramato, P, Varona, C, Palacios, J, Regadera, J, Aranda, A . Proc. Natl. Acad. Sci. U.S.A. - 113 (3) : E328-37 (PMID: 26729869) (doi:10.1073/pnas.1520469113)
1 Apr | 2015 Thyroid hormone signaling controls hair follicle stem cell function. Contreras-Jurado, C , Lorz, C, García-Serrano, L , Paramio, JM, Aranda, A . Mol. Biol. Cell - 26 (7) : 1263-1272 (PMID: 25657324) (doi:10.1091/mbc.E14-07-1251)
1 Jan | 2015 Thyroid hormone increases bulk histones expression by enhancing translational efficiency. Zambrano, A , García-Carpizo, V , Villamuera, R, Aranda, A . Mol. Endocrinol. - 29 (1) : 68-75 (PMID: 25422881) (doi:10.1210/me.2014-1235)
25 Sep | 2014 Impaired hair growth and wound healing in mice lacking thyroid hormone receptors. Contreras-Jurado, C , García-Serrano, L , Martínez-Fernández, M, Ruiz-Llorente, L , Paramio, JM, Aranda, A . PLoS ONE - 9 (9) : e108137 (PMID: 25254665) (doi:10.1371/journal.pone.0108137)
30 May | 2014 microRNAs 424 and 503 are mediators of the anti-proliferative and anti-invasive action of the thyroid hormone receptor beta. Ruiz-Llorente, L , Ardila-González, S, Fanjul, LF, Martínez-Iglesias, O , Aranda, A . Oncotarget - 5 (10) : 2918-2933 (PMID: 24796297)
6 Jan | 2014 The thyroid hormone receptor β induces DNA damage and premature senescence. Zambrano, A , García-Carpizo, V , Gallardo, ME , Villamuera, R, Gómez-Ferrería, MA, Pascual, A , Buisine, N, Sachs, LM, Garesse, R , Aranda, A . J. Cell Biol. - 204 (1) : 129-146 (PMID: 24395638) (doi:10.1083/jcb.201305084)
1 Sep | 2013 Receptors of thyroid hormones. Aranda, A , Alonso-Merino, E , Zambrano, A . Pediatr Endocrinol Rev - 11 (1) : 2-13 (PMID: 24079074)
30 Jul | 2013 Thyroid hormone receptors, cell growth and differentiation. Pascual, A , Aranda, A . Biochim. Biophys. Acta - 1830 (7) : 3908-3916 (PMID: 22484490) (doi:10.1016/j.bbagen.2012.03.012)
31 Jan | 2013 Synergy between RA and TLR3 promotes type I IFN-dependent apoptosis through upregulation of TRAIL pathway in breast cancer cells. Bernardo, AR, Cosgaya, JM , Aranda, A , Jiménez-Lara, AM . Cell Death Dis - 4 : e479 (PMID: 23370279) (doi:10.1038/cddis.2013.5)
1 Oct | 2011 Early thyroid hormone-induced gene expression changes in N2a-β neuroblastoma cells. Bedó, G, Pascual, A , Aranda, A . J. Mol. Neurosci. - 45 (2) : 76-86 (PMID: 20506002) (doi:10.1007/s12031-010-9389-y)
1 Oct | 2011 The growing role of gene methylation on endocrine function. García-Carpizo, V , Ruiz-Llorente, L , Fraga, M, Aranda, A . J. Mol. Endocrinol. - 47 (2) : R75-89 (PMID: 21803863) (doi:10.1530/JME-11-0059)
17 Aug | 2011 The thyroid hormone receptors modulate the skin response to retinoids. García-Serrano, L , Gomez-Ferrería, MA , Contreras-Jurado, C , Segrelles, C, Paramio, JM, Aranda, A . PLoS ONE - 6 (8) : e23825 (PMID: 21858227) (doi:10.1371/journal.pone.0023825)
8 Jul | 2011 The thyroid hormone receptors as modulators of skin proliferation and inflammation. Contreras-Jurado, C , García-Serrano, L , Gómez-Ferrería, M , Costa, C, Paramio, JM, Aranda, A . J. Biol. Chem. - 286 (27) : 24079-24088 (PMID: 21566120) (doi:10.1074/jbc.M111.218487)
1 Mar | 2011 The thyroid hormone receptors as tumor suppressors. Ruiz-Llorente, L , Martínez-Iglesias, O , García-Silva, S , Tenbaum, S, Regadera, J, Aranda, A . Horm Mol Biol Clin Investig - 5 (2) : 79-89 (PMID: 25961243) (doi:10.1515/HMBCI.2010.045)
17 Feb | 2011 Thyroid hormone receptor β1 domains responsible for the antagonism with the ras oncogene: role of corepressors. García-Silva, S , Martínez-Iglesias, O , Ruiz-Llorente, L , Aranda, A . Oncogene - 30 (7) : 854-864 (PMID: 20956942) (doi:10.1038/onc.2010.464)
1 Sep | 2010 Retinoic acid regulates myelin formation in the peripheral nervous system. Latasa, MJ , Ituero, M , Moran-Gonzalez, A , Aranda, A , Cosgaya, JM . Glia - 58 (12) : 1451-1464 (PMID: 20648638) (doi:10.1002/glia.21020)
1 Feb | 2010 Thyroid hormone antagonizes tumor necrosis factor-alpha signaling in pituitary cells through the induction of dual specificity phosphatase 1. Lasa, M , Gil-Araujo, B , Palafox, M, Aranda, A . Mol. Endocrinol. - 24 (2) : 412-422 (PMID: 20032197) (doi:10.1210/me.2009-0298)
26 Jan | 2010 Retinoic acid protects human breast cancer cells against etoposide-induced apoptosis by NF-kappaB-dependent but cIAP2-independent mechanisms. Jiménez-Lara, AM , Aranda, A , Gronemeyer, H. Mol. Cancer - 9 : 15 (PMID: 20102612) (doi:10.1186/1476-4598-9-15)
14 Jan | 2010 Mice lacking thyroid hormone receptor Beta show enhanced apoptosis and delayed liver commitment for proliferation after partial hepatectomy. López-Fontal, R, Zeini, M, Través, PG , Gómez-Ferrería, M , Aranda, A , Sáez, GT, Cerdá, C, Martín-Sanz, P , Hortelano, S, Boscá, L . PLoS ONE - 5 (1) : e8710 (PMID: 20090848) (doi:10.1371/journal.pone.0008710)
16 Nov | 2009 Residues K128, 132, and 134 in the thyroid hormone receptor-alpha are essential for receptor acetylation and activity. Sánchez-Pacheco, A , Martínez-Iglesias, O , Méndez-Pertuz, M, Aranda, A . Endocrinology - 150 (11) : 5143-5152 (PMID: 19819978) (doi:10.1210/en.2009-0117)
14 Sep | 2009 Thyroid receptor: roles in cancer. Aranda, A , Martínez-Iglesias, O , Ruiz-Llorente, L , García-Carpizo, V , Zambrano, A . Trends Endocrinol. Metab. - 20 (7) : 318-324 (PMID: 19716314) (doi:10.1016/j.tem.2009.03.011)
29 Jul | 2009 Hypothyroidism enhances tumor invasiveness and metastasis development. Martínez-Iglesias, O , García-Silva, S , Regadera, J, Aranda, A . PLoS ONE - 4 (7) : e6428 (PMID: 19641612) (doi:10.1371/journal.pone.0006428)
12 Mar | 2009 Activation of the unliganded estrogen receptor by prolactin in breast cancer cells. González, L, Zambrano, A , Lazaro-Trueba, I, Lopéz, E, González, JJ, Martín-Pérez, J , Aranda, A . Oncogene - 28 (10) : 1298-1308 (PMID: 19169277) (doi:10.1038/onc.2008.473)
15 Jan | 2009 Thyroid hormone receptor beta1 acts as a potent suppressor of tumor invasiveness and metastasis. Martínez-Iglesias, O , Garcia-Silva, S, Tenbaum, SP , Regadera, J, Larcher, F, Paramio, JM, Vennström, B, Aranda, A . Cancer Res. - 69 (2) : 501-509 (PMID: 19147563) (doi:10.1158/0008-5472.CAN-08-2198)
1 Nov | 2008 Thyroid hormone-mediated activation of the ERK/dual specificity phosphatase 1 pathway augments the apoptosis of GH4C1 cells by down-regulating nuclear factor-kappaB activity. Chiloeches, A, Sánchez-Pacheco, A , Gil-Araujo, B , Aranda, A , Lasa, M . Mol. Endocrinol. - 22 (11) : 2466-2480 (PMID: 18755855) (doi:10.1210/me.2008-0107)
16 Jul | 2008 Histone deacetylase inhibitors: mechanism of action and therapeutic use in cancer. Martínez-Iglesias, O , Ruiz-Llorente, L , Sánchez-Martínez, R, García, L, Zambrano, A , Aranda, A . Clin Transl Oncol - 10 (7) : 395-398 (PMID: 18628067)
16 Jun | 2008 Vitamin D-dependent recruitment of corepressors to vitamin D/retinoid X receptor heterodimers. Sánchez-Martínez, R , Zambrano, A , Castillo, AI , Aranda, A . Mol. Cell. Biol. - 28 (11) : 3817-3829 (PMID: 18362166) (doi:10.1128/MCB.01909-07)
1 Dec | 2007 Anti-estrogenic actions of histone deacetylase inhibitors in MCF-7 breast cancer cells. De los Santos, M , Martínez-Iglesias, O , Aranda, A . Endocr. Relat. Cancer - 14 (4) : 1021-1028 (PMID: 18045953) (doi:10.1677/ERC-07-0144)
1 Oct | 2007 Histone deacetylase inhibitors regulate retinoic acid receptor beta expression in neuroblastoma cells by both transcriptional and posttranscriptional mechanisms. De los Santos, M , Zambrano, A , Sánchez-Pacheco, A , Aranda, A . Mol. Endocrinol. - 21 (10) : 2416-2426 (PMID: 17622583) (doi:10.1210/me.2007-0151)
8 Jun | 2007 Activation of the human immunodeficiency virus type I long terminal repeat by 1 alpha,25-dihydroxyvitamin D3. Nevado, J , Tenbaum, SP , Castillo, AI , Sánchez-Pacheco, A , Aranda, A . J. Mol. Endocrinol. - 38 (6) : 587-601 (PMID: 17556530) (doi:10.1677/JME-06-0065)
13 Apr | 2007 Combined effects of retinoic acid and histone deacetylase inhibitors on human neuroblastoma SH-SY5Y cells. De los Santos, M , Zambrano, A , Aranda, A . Mol. Cancer Ther. - 6 (4) : 1425-1432 (PMID: 17431121) (doi:10.1158/1535-7163.MCT-06-0623)
1 Dec | 2006 Characterization of vitamin D receptor ligands with cell-specific and dissociated activity. Castillo, AI , Sánchez-Martínez, R , Jiménez-Lara, AM , Steinmeyer, A, Zügel, U, Aranda, A . Mol. Endocrinol. - 20 (12) : 3093-3104 (PMID: 16901972) (doi:10.1210/me.2006-0215)
3 Oct | 2006 The retinoid X receptor ligand restores defective signalling by the vitamin D receptor. Sánchez-Martínez, R , Castillo, AI , Steinmeyer, A, Aranda, A . EMBO Rep. - 7 (10) : 1030-1034 (PMID: 16936639) (doi:10.1038/sj.embor.7400776)
28 Jul | 2006 Role of c-Src in human MCF7 breast cancer cell tumorigenesis. González, L , Agulló-Ortuño, MT , García-Martínez, JM , Calcabrini, A , Gamallo, C , Palacios, J, Aranda, A , Martín-Pérez, J . J. Biol. Chem. - 281 (30) : 20851-20864 (PMID: 16728403) (doi:10.1074/jbc.M601570200)
17 Mar | 2006 The molecular basis of vitamin D receptor and beta-catenin crossregulation. Shah, S, Islam, MN, Dakshanamurthy, S, Rizvi, I, Rao, M, Herrell, R, Zinser, G, Valrance, M, Aranda, A , Moras, D, Norman, A, Welsh, J, Byers, SW. Mol. Cell - 21 (6) : 799-809 (PMID: 16543149) (doi:10.1016/j.molcel.2006.01.037)
22 Apr | 2005 The repressor DREAM acts as a transcriptional activator on Vitamin D and retinoic acid response elements. Scsucova, S, Palacios, D , Savignac, M, Mellström, B, Naranjo, JR, Aranda, A . Nucleic Acids Res. - 33 (7) : 2269-2279 (PMID: 15849313) (doi:10.1093/nar/gki503)
1 Dec | 2004 Rapid effects of retinoic acid on CREB and ERK phosphorylation in neuronal cells. Cañón, E , Cosgaya, JM , Scsucova, S, Aranda, A . Mol. Biol. Cell - 15 (12) : 5583-5592 (PMID: 15371543) (doi:10.1091/mbc.E04-05-0439)
30 Sep | 2004 The thyroid hormone receptor is a suppressor of ras-mediated transcription, proliferation, and transformation. García-Silva, S , Aranda, A . Mol. Cell. Biol. - 24 (17) : 7514-7523 (PMID: 15314161) (doi:10.1128/MCB.24.17.7514-7523.2004)
30 Jul | 2004 hSrb7, an essential human Mediator component, acts as a coactivator for the thyroid hormone receptor. Nevado, J , Tenbaum, SP , Aranda, A . Mol. Cell. Endocrinol. - 222 (1-2) : 41-51 (PMID: 15249124) (doi:10.1016/j.mce.2004.05.003)
1 Jan | 2004 A permissive retinoid X receptor/thyroid hormone receptor heterodimer allows stimulation of prolactin gene transcription by thyroid hormone and 9-cis-retinoic acid. Castillo, AI , Sánchez-Martínez, R , Moreno, JL, Martínez-Iglesias, OA, Palacios, D , Aranda, A . Mol. Cell. Biol. - 24 (2) : 502-513 (PMID: 14701725)
10 Oct | 2003 Binding of the thyroid hormone receptor to a negative element in the basal growth hormone promoter is associated with histone acetylation. Sánchez-Pacheco, A , Aranda, A . J. Biol. Chem. - 278 (41) : 39383-39391 (PMID: 12878587) (doi:10.1074/jbc.M306988200)
16 Jun | 2003 The thyroid hormone receptor antagonizes CREB-mediated transcription. Méndez-Pertuz, M, Sánchez-Pacheco, A , Aranda, A . EMBO J. - 22 (12) : 3102-3112 (PMID: 12805224) (doi:10.1093/emboj/cdg295)
27 Dec | 2002 Cell cycle control by the thyroid hormone in neuroblastoma cells. Garcia-Silva, S, Perez-Juste, G, Aranda, A . Toxicology - 181-182 : 179-182 (PMID: 12505306)
26 Jul | 2001 Nuclear hormone receptors and gene expression. Aranda, A , Pascual, A . Physiol. Rev. - 81 (3) : 1269-1304 (PMID: 11427696)
22 Feb | 2001 Nerve growth factor activates the RARbeta2 promoter by a Ras-dependent mechanism. Cosgaya, JM , Aranda, A . J. Neurochem. - 76 (3) : 661-671 (PMID: 11158236)
19 Dec | 2000 Association with Ets-1 causes ligand- and AF2-independent activation of nuclear receptors. Tolón, RM , Castillo, AI , Jiménez-Lara, AM , Aranda, A . Mol. Cell. Biol. - 20 (23) : 8793-8802 (PMID: 11073980)
14 Jul | 2000 Differentiation of lactotrope precursor GHFT cells in response to fibroblast growth factor-2. López-Fernández, J, Palacios, D, Castillo, AI , Tolon, RM , Aranda, A , Karin, M. J. Biol. Chem. - 275 (28) : 21653-21660 (PMID: 10801832) (doi:10.1074/jbc.M002129200)
1 Apr | 2000 Interaction of vitamin D and retinoid receptors on regulation of gene expression. Jimenez-Lara, AM , Aranda, A . Horm. Res. - 54 (5-6) : 301-305 (PMID: 11595822) (doi:53276)
3 Mar | 2000 Retinoic acid stimulates HIV-1 transcription in human neuroblastoma SH-SY5Y cells. Recio, JA , Martínez de la Mata, J, Martín-Nieto, J , Aranda, A . FEBS Lett. - 469 (1) : 118-122 (PMID: 10708768)
14 Jan | 2000 An element in the region responsible for premature termination of transcription mediates repression of c-myc gene expression by thyroid hormone in neuroblastoma cells. Pérez-Juste, G, García-Silva, S , Aranda, A . J. Biol. Chem. - 275 (2) : 1307-1314 (PMID: 10625678)
23 Sep | 1999 Differentiation of neuroblastoma cells by phorbol esters and insulin-like growth factor 1 is associated with induction of retinoic acid receptor beta gene expression. Perez-Juste, G , Aranda, A . Oncogene - 18 (39) : 5393-5402 (PMID: 10498893) (doi:10.1038/sj.onc.1202906)
1 Jul | 1999 Synergistic activation of the prolactin promoter by vitamin D receptor and GHF-1: role of the coactivators, CREB-binding protein and steroid hormone receptor coactivator-1 (SRC-1). Castillo, AI , Jimenez-Lara, AM , Tolon, RM , Aranda, A . Mol. Endocrinol. - 13 (7) : 1141-1154 (PMID: 10406465) (doi:10.1210/mend.13.7.0320)
14 Jun | 1999 The vitamin D receptor binds in a transcriptionally inactive form and without a defined polarity on a retinoic acid response element. Jimenez-Lara, AM , Aranda, A . FASEB J. - 13 (9) : 1073-1081 (PMID: 10336890)
3 Jun | 1999 Vitamin D represses retinoic acid-dependent transactivation of the retinoic acid receptor-beta2 promoter: the AF-2 domain of the vitamin D receptor is required for transrepression. Jiménez-Lara, AM , Aranda, A . Endocrinology - 140 (6) : 2898-2907 (PMID: 10342883) (doi:10.1210/endo.140.6.6770)
7 May | 1999 Lysine 246 of the vitamin D receptor is crucial for ligand-dependent interaction with coactivators and transcriptional activity. Jiménez-Lara, AM , Aranda, A . J. Biol. Chem. - 274 (19) : 13503-13510 (PMID: 10224118)
26 Feb | 1999 The ras oncogene inhibits growth factor inducibility of early response genes, and promotes selectively expression of NGFI-A in a PC12 cell line. Cosgaya, JM , Aranda, A . FEBS Lett. - 445 (2-3) : 329-332 (PMID: 10094483)
19 Feb | 1999 The cyclin-dependent kinase inhibitor p27(Kip1) is involved in thyroid hormone-mediated neuronal differentiation. Perez-Juste, G , Aranda, A . J. Biol. Chem. - 274 (8) : 5026-5031 (PMID: 9988748)
16 Oct | 1998 Role of GHF-1 in the regulation of the rat growth hormone gene promoter by thyroid hormone and retinoic acid receptors. Palomino, T , Barettino, D , Aranda, A . J. Biol. Chem. - 273 (42) : 27541-27547 (PMID: 9765286)
9 Oct | 1998 Activation of the prolactin gene by peroxisome proliferator-activated receptor-alpha appears to be DNA binding-independent. Tolón, RM , Castillo, AI , Aranda, A . J. Biol. Chem. - 273 (41) : 26652-26661 (PMID: 9756906)
29 Sep | 1998 A direct protein-protein interaction is involved in the cooperation between thyroid hormone and retinoic acid receptors and the transcription factor GHF-1. Palomino, T , Sánchez-Pacheco, A , Peña, P , Aranda, A . FASEB J. - 12 (12) : 1201-1209 (PMID: 9737723)
1 Aug | 1998 Neuronal differentiation of PC12 cells induced by engrailed homeodomain is DNA-binding specific and independent of MAP kinases. Cosgaya, JM , Aranda, A , Cruces, J , Martín-Blanco, E. J. Cell. Sci. - 111 ( Pt 16) : 2377-2384 (PMID: 9683632)
16 Jun | 1998 Retinoic acid regulates selectively the expression of immediate early response genes in PC12 cells. Cosgaya, JM , Pérez-Juste, G, Aranda, A . FEBS Lett. - 429 (3) : 254-258 (PMID: 9662427)
16 Apr | 1998 Insulin-like growth factor-1 stimulates rat prolactin gene expression by a Ras, ETS and phosphatidylinositol 3-kinase dependent mechanism. Castillo, AI , Tolon, RM , Aranda, A . Oncogene - 16 (15) : 1981-1991 (PMID: 9591782) (doi:10.1038/sj.onc.1200204)
23 Jan | 1998 The transcription factor GHF-1, but not the splice variant GHF-2, cooperates with thyroid hormone and retinoic acid receptors to stimulate rat growth hormone gene expression. Sánchez-Pacheco, A , Peña, P , Palomino, T , Güell, A, Castrillo, JL, Aranda, A . FEBS Lett. - 422 (1) : 103-107 (PMID: 9475179)
29 Dec | 1997 Differential regulation of pituitary-specific gene expression by insulin-like growth factor 1 in rat pituitary GH4C1 and GH3 cells. Castillo, AI , Aranda, A . Endocrinology - 138 (12) : 5442-5451 (PMID: 9389530) (doi:10.1210/endo.138.12.5585)
24 Oct | 1997 Activation of the HIV-1 long terminal repeat by nerve growth factor. Recio, JA , Aranda, A . J. Biol. Chem. - 272 (43) : 26807-26810 (PMID: 9341108)
10 Apr | 1997 Influence of Ras and retinoic acid on nerve growth factor induction of transin gene expression in PC12 cells. Cosgaya, JM , Recio, JA , Aranda, A . Oncogene - 14 (14) : 1687-1696 (PMID: 9135070) (doi:10.1038/sj.onc.1200997)
1 Apr | 1997 Growth factor ligands of tyrosine kinase receptors activate the Rous sarcoma virus promoter by a Ras- and Raf-dependent mechanism. Cosgaya, JM , Perez-Juste, G , Castillo, AI , Aranda, A . Gene - 188 (2) : 291-293 (PMID: 9133605)
1 Apr | 1997 Histone acetylation influences thyroid hormone and retinoic acid-mediated gene expression. Garcia-Villalba, P, Jimenez-Lara, AM , Castillo, AI , Aranda, A . DNA Cell Biol. - 16 (4) : 421-431 (PMID: 9150429)
6 Feb | 1997 Retinoic acid induces secretion of transforming growth factors by PC12 pheochromocytoma cells. Cosgaya, JM , Perona, R , Aranda, A . Oncogene - 14 (5) : 579-587 (PMID: 9053856) (doi:10.1038/sj.onc.1200865)
20 Jun | 1996 Ras- and Raf-mediated regulation of transforming growth factor beta 1 gene expression by ligands of tyrosine kinase receptors in PC12 cells. Cosgaya, JM , Aranda, A . Oncogene - 12 (12) : 2651-2660 (PMID: 8700524)
24 Jan | 1996 Comparison of the effects of retinoic acid and nerve growth factor on PC12 cell proliferation, differentiation, and gene expression. Cosgaya, JM , Garcia-Villalba, P, Perona, R , Aranda, A . J. Neurochem. - 66 (1) : 89-98 (PMID: 8522994)
19 Jan | 1996 Vitamin D interferes with transactivation of the growth hormone gene by thyroid hormone and retinoic acid. Garcia-Villalba, P, Jimenez-Lara, AM , Aranda, A . Mol. Cell. Biol. - 16 (1) : 318-327 (PMID: 8524311)
28 Dec | 1995 Retinoic acid induces expression of the transcription factor GHF-1/Pit-1 in pituitary prolactin- and growth hormone-producing cell lines. Sánchez-Pacheco, A , Palomino, T , Aranda, A . Endocrinology - 136 (12) : 5391-5398 (PMID: 7588287) (doi:10.1210/endo.136.12.7588287)
15 Dec | 1995 Nerve growth factor regulates transforming growth factor-beta 1 gene expression by both transcriptional and posttranscriptional mechanisms in PC12 cells. Cosgaya, JM , Aranda, A . J. Neurochem. - 65 (6) : 2484-2490 (PMID: 7595542)
21 Nov | 1995 Negative regulation of expression of the pituitary-specific transcription factor GHF-1/Pit-1 by thyroid hormones through interference with promoter enhancer elements. Sanchez-Pacheco, A , Palomino, T , Aranda, A . Mol. Cell. Biol. - 15 (11) : 6322-6330 (PMID: 7565785)
30 Nov | 1994 Determination of the promoter elements that mediate repression of c-fos gene transcription by thyroid hormone and retinoic acid receptors. Perez, P, Palomino, T , Schönthal, A, Aranda, A . Biochem. Biophys. Res. Commun. - 205 (1) : 135-140 (PMID: 7999013) (doi:10.1006/bbrc.1994.2640)
5 Nov | 1993 Repression of c-fos gene expression by thyroid hormone and retinoic acid receptors. Perez, P, Schönthal, A, Aranda, A . J. Biol. Chem. - 268 (31) : 23538-23543 (PMID: 8226882)
15 Mar | 1993 Interaction of thyroid hormone and retinoic acid receptors on the regulation of the rat growth hormone gene promoter. García-Villalba, P, Au-Fliegner, M, Samuels, HH, Aranda, A . Biochem. Biophys. Res. Commun. - 191 (2) : 580-586 (PMID: 8384845)
1 Feb | 1993 Nicotinamide analogs and DNA-damaging agents deplete thyroid hormone receptor and c-erbA mRNA levels in pituitary GH1 cells. Sanchez-Pacheco, A , Perez, P, Villa, A, Pascual, A , Aranda, A . Mol. Cell. Endocrinol. - 91 (1-2) : 127-134 (PMID: 8386110)
2 Nov | 1992 The thyroid hormone response element is required for activation of the growth hormone gene promoter by nicotinamide analogs. Sánchez-Pacheco, A , Aranda, A . FEBS Lett. - 312 (1) : 42-46 (PMID: 1426237)
27 Nov | 1991 Retinoic acid decreases thyroid hormone receptor expression in pituitary GH1 cells. Pérez, P, Sánchez-Pacheco, A , Pascual, A , Aranda, A . Biochem. Biophys. Res. Commun. - 181 (1) : 9-15 (PMID: 1720314)
1 Nov | 1991 Expression of the growth hormone gene and the pituitary-specific transcription factor GHF-1 in diabetic rats. Bedo, G, Santisteban, P , Jolin, T, Aranda, A . Mol. Endocrinol. - 5 (11) : 1730-1739 (PMID: 1779974) (doi:10.1210/mend-5-11-1730)
18 May | 1989 Retinoic acid regulates growth hormone gene expression. Bedo, G, Santisteban, P , Aranda, A . Nature - 339 (6221) : 231-234 (PMID: 2716850) (doi:10.1038/339231a0)
15 Jan | 1988 Cholera toxin affects nuclear ADP-ribosylation in GH1 cells. Aranda, A , Pascual, A , Copp, R, Samuels, H. Biochem. Biophys. Res. Commun. - 150 (1) : 323-328 (PMID: 2827673)
1 Mar | 1981 A survey of schoolchildren from a severe endemic goitre area in Spain. Escobar del Rey, F , Gomez-Pan, A, Obregon, MJ , Mallol, J, Arnao, MD, Aranda, A , Morreale de Escobar, G . Q. J. Med. - 50 (198) : 233-246 (PMID: 7302120)