1 Oct | 2022 p73 is required for vessel integrity controlling endothelial junctional dynamics through Angiomotin. Maeso-Alonso, L, Alonso-Olivares, H, Martínez-García, N, López-Ferreras, L, Villoch-Fernández, J, Puente-Santamaría, L , Colas-Algora, N, Fernández-Corona, A, Lorenzo-Marcos, ME, Jiménez, B , Holmgren, L, Wilhelm, M, Millan, J, Del Peso, L , Claesson-Welsh, L, Marques, MM, Marin, MC. Cell Mol Life Sci - 79 (10) : 535 (PMID: 36180740) (doi:10.1007/s00018-022-04560-3)
8 Sep | 2022 Formal Meta-Analysis of Hypoxic Gene Expression Profiles Reveals a Universal Gene Signature. Puente-Santamaria, L , Sanchez-Gonzalez, L , Pescador, N , Martinez-Costa, O , Ramos-Ruiz, R, Del Peso, L . Biomedicines - 10 (9) (PMID: 36140330) (doi:10.3390/biomedicines10092229)
19 Jul | 2022 ERK5 Is a Major Determinant of Chemical Sarcomagenesis: Implications in Human Pathology. Arconada-Luque, E, Jiménez-Suarez, J, Pascual-Serra, R, Nam-Cha, SH, Moline, T, Cimas, FJ, Fliquete, G, Ortega-Muelas, M, Roche, O , Fernández-Aroca, DM, Muñoz Velasco, R, García-Flores, N, Garnés-García, C, Sánchez-Fdez, A, Matilla-Almazán, S, Sánchez-Arévalo Lobo, VJ, Hernández-Losa, J, Belandia, B , Pandiella, A, Esparís-Ogando, A, Ramón Y Cajal, S, Del Peso, L , Sánchez-Prieto, R , Ruiz-Hidalgo, MJ. Cancers (Basel) - 14 (14) (PMID: 35884568) (doi:10.3390/cancers14143509)
31 May | 2022 Hypoxia classifier for transcriptome datasets. Puente-Santamaría, L , Sanchez-Gonzalez, L , Ramos-Ruiz, R, Del Peso, L . BMC Bioinformatics - 23 (1) : 204 (PMID: 35641902) (doi:10.1186/s12859-022-04741-8)
15 Aug | 2020 Comparative Study of Organoids from Patient-Derived Normal and Tumor Colon and Rectal Tissue. Costales-Carrera, A , Fernández-Barral, A , Bustamante-Madrid, P , Domínguez, O, Guerra-Pastrián, L, Cantero, R, Del Peso, L , Burgos, A, Barbáchano, A , Muñoz, A . Cancers (Basel) - 12 (8) (PMID: 32824266) (doi:10.3390/cancers12082302)
1 Aug | 2020 Metabolic labeling of RNA uncovers the contribution of transcription and decay rates on hypoxia-induced changes in RNA levels. Tiana, M , Acosta-Iborra, B , Hernández, R , Galiana, C , Fernández-Moreno, MÁ , Jimenez, B , Del Peso, L . RNA - 26 (8) : 1006-1022 (PMID: 32295863) (doi:10.1261/rna.072611.119)
29 Mar | 2020 Hypoxia compensates cell cycle arrest with progenitor differentiation during angiogenesis. Acosta-Iborra, B , Tiana, M , Maeso-Alonso, L, Hernández-Sierra, R , Herranz, G , Santamaria, A , Rey, C , Luna, R , Puente-Santamaria, L , Marques, MM, Marin, MC, Del Peso, L , Jiménez, B . FASEB J. (PMID: 32223018) (doi:10.1096/fj.201903082R)
1 Jan | 2020 Vitamin D differentially regulates colon stem cells in patient-derived normal and tumor organoids. Fernández-Barral, A , Costales-Carrera, A , Buira, SP, Jung, P, Ferrer-Mayorga, G , Larriba, MJ , Bustamante-Madrid, P , Domínguez, O, Real, FX, Guerra-Pastrián, L, Lafarga, M, García-Olmo, D, Cantero, R, Del Peso, L , Batlle, E, Rojo, F, Muñoz, A , Barbáchano, A . FEBS J. - 287 (1) : 53-72 (PMID: 31306552) (doi:10.1111/febs.14998)
15 Dec | 2019 TFEA.ChIP: a tool kit for transcription factor binding site enrichment analysis capitalizing on ChIP-seq datasets. Puente-Santamaria, L , Wasserman, WW, Del Peso, L . Bioinformatics - 35 (24) : 5339-5340 (PMID: 31347689) (doi:10.1093/bioinformatics/btz573)
1 Jul | 2019 Intussusceptive Vascular Remodeling Precedes Pathological Neovascularization. Ali, Z, Mukwaya, A, Biesemeier, A, Ntzouni, M, Ramsköld, D, Giatrellis, S, Mammadzada, P, Cao, R, Lennikov, A, Marass, M, Gerri, C, Hildesjö, C, Taylor, M, Deng, Q, Peebo, B, Del Peso, L , Kvanta, A, Sandberg, R, Schraermeyer, U, Andre, H, Steffensen, JF, Lagali, N, Cao, Y, Kele, J, Jensen, LD. Arterioscler. Thromb. Vasc. Biol. - 39 (7) : 1402-1418 (PMID: 31242036) (doi:10.1161/ATVBAHA.118.312190)
30 May | 2019 Vitamin D and Wnt3A have additive and partially overlapping modulatory effects on gene expression and phenotype in human colon fibroblasts. Ferrer-Mayorga, G , Niell, N , Cantero, R, González-Sancho, JM , Del Peso, L , Muñoz, A , Larriba, MJ . Sci Rep - 9 (1) : 8085 (PMID: 31147591) (doi:10.1038/s41598-019-44574-9)
22 Apr | 2018 Hypoxia and Chromatin: A Focus on Transcriptional Repression Mechanisms. Batie, M, Del Peso, L , Rocha, S. Biomedicines - 6 (2) (PMID: 29690561) (doi:10.3390/biomedicines6020047)
15 Feb | 2018 The human PKP2/plakophilin-2 gene is induced by Wnt/β-catenin in normal and colon cancer-associated fibroblasts. Niell, N , Larriba, MJ , Ferrer-Mayorga, G , Sánchez-Pérez, I , Cantero, R, Real, FX, Del Peso, L , Muñoz, A , González-Sancho, JM . Int. J. Cancer - 142 (4) : 792-804 (PMID: 29044515) (doi:10.1002/ijc.31104)
9 Jan | 2018 The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia. Tiana, M , Acosta-Iborra, B , Puente-Santamaría, L , Hernansanz-Agustin, P , Worsley-Hunt, R, Masson, N, García-Rio, F, Mole, D, Ratcliffe, P, Wasserman, WW, Jimenez, B , Del Peso, L . Nucleic Acids Res. - 46 (1) : 120-133 (PMID: 29059365) (doi:10.1093/nar/gkx951)
1 Aug | 2017 Classification of Airflow Limitation Based on z-Score Underestimates Mortality in Patients with Chronic Obstructive Pulmonary Disease. Tejero, E, Prats, E, Casitas, R, Galera, R, Pardo, P, Gavilán, A, Martínez-Cerón, E, Cubillos-Zapata, C, Del Peso, L , García-Río, F. Am. J. Respir. Crit. Care Med. - 196 (3) : 298-305 (PMID: 28306326) (doi:10.1164/rccm.201611-2265OC)
12 Sep | 2016 Identification of non-coding genetic variants in samples from hypoxemic respiratory disease patients that affect the transcriptional response to hypoxia. Roche, O , Deguiz, ML, Tiana, M, Galiana-Ribote, C, Martinez-Alcazar, D, Rey-Serra, C, Ranz-Ribeiro, B, Casitas, R, Galera, R, Fernández-Navarro, I, Sánchez-Cuéllar, S, Bernard, V, Ancochea, J, Wasserman, WW, García-Rio, F, Jimenez, B , Del Peso, L . Nucleic Acids Res. (PMID: 27625398) (doi:10.1093/nar/gkw811)
23 Sep | 2015 lnc RNAs, hypoxia and metastasis. Jiménez, B , Tiana, M, Del Peso, L . Oncoscience - 2 (10) : 795-796 (PMID: 26682249) (doi:10.18632/oncoscience.247)
14 May | 2015 EFNA3 long noncoding RNAs induced by hypoxia promote metastatic dissemination. Gómez-Maldonado, L, Tiana, M, Roche, O, Prado-Cabrero, A, Jensen, L, Fernandez-Barral, A, Guijarro-Muñoz, I, Favaro, E, Moreno-Bueno, G , Sanz, L, Aragones, J, Harris, A, Volpert, O, Jimenez, B , del Peso, L . Oncogene - 34 (20) : 2609-2620 (PMID: 25023702) (doi:10.1038/onc.2014.200)
13 Jun | 2014 Improving analysis of transcription factor binding sites within ChIP-Seq data based on topological motif enrichment. Worsley Hunt, R, Mathelier, A, Del Peso, L , Wasserman, WW. BMC Genomics - 15 : 472 (PMID: 24927817) (doi:10.1186/1471-2164-15-472)
1 Jun | 2014 Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma. Fernández-Barral, A , Orgaz, JL , Baquero, P, Ali, Z, Moreno, A , Tiana, M, Gómez, V, Riveiro-Falkenbach, E, Cañadas, C, Zazo, S, Bertolotto, C, Davidson, I, Rodríguez-Peralto, JL, Palmero, I , Rojo, F, Jensen, LD, del Peso, L , Jiménez, B . Neoplasia - 16 (6) : 529-542 (PMID: 25030625) (doi:10.1016/j.neo.2014.06.001)
13 Feb | 2014 Interaction between PARP-1 and HIF-2α in the hypoxic response. Gonzalez-Flores, A, Aguilar-Quesada, R, Siles, E, Pozo, S, Rodríguez-Lara, MI, López-Jiménez, L, López-Rodríguez, M, Peralta-Leal, A, Villar, D, Martín-Oliva, D, del Peso, L , Berra, E, Oliver, FJ. Oncogene - 33 (7) : 891-898 (PMID: 23455322) (doi:10.1038/onc.2013.9)
4 Jun | 2013 ERK5/BMK1 is a novel target of the tumor suppressor VHL: implication in clear cell renal carcinoma. Arias-González, L, Moreno-Gimeno, I, del Campo, AR, Serrano-Oviedo, L, Valero, ML, Esparís-Ogando, A, de la Cruz-Morcillo, MÁ, Melgar-Rojas, P, García-Cano, J, Cimas, FJ, Hidalgo, MJ, Prado, A, Callejas-Valera, JL, Nam-Cha, SH, Giménez-Bachs, JM, Salinas-Sánchez, AS, Pandiella, A, del Peso, L , Sánchez-Prieto, R . Neoplasia - 15 (6) : 649-659 (PMID: 23730213)
9 Mar | 2013 The use of an active learning approach to teach metabolism to students of nutrition and dietetics. González-Sancho, JM , Sánchez-Pacheco, A , Lasa, M , Molina, S, Vara, F , del Peso, L . Biochem Mol Biol Educ - 41 (3) : 131-138 (PMID: 23483652) (doi:10.1002/bmb.20684)
24 Sep | 2012 Cooperativity of stress-responsive transcription factors in core hypoxia-inducible factor binding regions. Villar, D , Ortiz-Barahona, A , Gómez-Maldonado, L, Pescador, N , Sánchez-Cabo, F, Hackl, H, Rodriguez, BA, Trajanoski, Z, Dopazo, A, Huang, TH, Yan, PS, Del Peso, L . PLoS ONE - 7 (9) : e45708 (PMID: 23029193) (doi:10.1371/journal.pone.0045708)
20 Sep | 2012 The transcription factor encyclopedia. Yusuf, D, Butland, SL, Swanson, MI, Bolotin, E, Ticoll, A, Cheung, WA, Zhang, XY, Dickman, CT, Fulton, DL, Lim, JS, Schnabl, JM, Ramos, OH, Vasseur-Cognet, M, de Leeuw, CN, Simpson, EM, Ryffel, GU, Lam, EW, Kist, R, Wilson, MS, Marco-Ferreres, R , Brosens, JJ, Beccari, LL, Bovolenta, P, Benayoun, BA, Monteiro, LJ, Schwenen, HD, Grontved, L, Wederell, E, Mandrup, S, Veitia, RA, Chakravarthy, H, Hoodless, PA, Mancarelli, MM, Torbett, BE, Banham, AH, Reddy, SP, Cullum, RL, Liedtke, M, Tschan, MP, Vaz, M, Rizzino, A, Zannini, M, Frietze, S, Farnham, PJ, Eijkelenboom, A, Brown, PJ, Laperrière, D, Leprince, D, de Cristofaro, T, Prince, KL, Putker, M, del Peso, L , Camenisch, G, Wenger, RH, Mikula, M, Rozendaal, M, Mader, S, Ostrowski, J, Rhodes, SJ, Van Rechem, C, Boulay, G, Olechnowicz, SW, Breslin, MB, Lan, MS, Nanan, KK, Wegner, M, Hou, J, Mullen, RD, Colvin, SC, Noy, PJ, Webb, CF, Witek, ME, Ferrell, S, Daniel, JM, Park, J, Waldman, SA, Peet, DJ, Taggart, M, Jayaraman, PS, Karrich, JJ, Blom, B, Vesuna, F, O'Geen, H, Sun, Y, Gronostajski, RM, Woodcroft, MW, Hough, MR, Chen, E, Europe-Finner, GN, Karolczak-Bayatti, M, Bailey, J, Hankinson, O, Raman, V, LeBrun, DP, Biswal, S, Harvey, CJ, DeBruyne, JP, Hogenesch, JB, Hevner, RF, Héligon, C, Luo, XM, Blank, MC, Millen, KJ, Sharlin, DS, Forrest, D, Dahlman-Wright, K, Zhao, C, Mishima, Y, Sinha, S, Chakrabarti, R, Portales-Casamar, E, Sladek, FM, Bradley, PH, Wasserman, WW. Genome Biol. - 13 (3) : R24 (PMID: 22458515) (doi:10.1186/gb-2012-13-3-r24)
4 Sep | 2012 miR-127 protects proximal tubule cells against ischemia/reperfusion: identification of kinesin family member 3B as miR-127 target. Aguado-Fraile, E, Ramos, E, Sáenz-Morales, D, Conde, E, Blanco-Sánchez, I, Stamatakis, K, del Peso, L , Cuppen, E, Brüne, B, Bermejo, ML. PLoS ONE - 7 (9) : e44305 (PMID: 22962609) (doi:10.1371/journal.pone.0044305)
23 Mar | 2012 Hypoxia negatively regulates antimetastatic PEDF in melanoma cells by a hypoxia inducible factor-independent, autophagy dependent mechanism. Fernández-Barral, A , Orgaz, JL , Gomez, V, del Peso, L , Calzada, MJ, Jiménez, B . PLoS ONE - 7 (3) : e32989 (PMID: 22457728) (doi:10.1371/journal.pone.0032989)
14 Mar | 2012 A role for insulator elements in the regulation of gene expression response to hypoxia. Tiana, M , Villar, D , Pérez-Guijarro, E , Gómez-Maldonado, L, Moltó, E, Fernández-Miñán, A, Gómez-Skarmeta, JL, Montoliu, L, del Peso, L . Nucleic Acids Res. - 40 (5) : 1916-1927 (PMID: 22067454) (doi:10.1093/nar/gkr842)
14 Mar | 2012 Hypoxia inducible factor 1-alpha (HIF-1 alpha) is induced during reperfusion after renal ischemia and is critical for proximal tubule cell survival. Conde, E, Alegre, L, Blanco-Sánchez, I, Sáenz-Morales, D, Aguado-Fraile, E, Ponte, B, Ramos, E, Sáiz, A, Jiménez, C, Ordoñez, A, López-Cabrera, M, del Peso, L , de Landázuri, MO, Liaño, F, Selgas, R, Sanchez-Tomero, JA, García-Bermejo, ML. PLoS ONE - 7 (3) : e33258 (PMID: 22432008) (doi:10.1371/journal.pone.0033258)
1 Sep | 2011 Non-invasive monitoring of hypoxia-inducible factor activation by optical imaging during antiangiogenic treatment in a xenograft model of ovarian carcinoma. Martinez-Poveda, B, Gomez, V, Alcaide-German, M , Perruca, S , Vazquez, S, Alba, LE, Casanovas, O, Garcia-Bermejo, ML, Peso, L , Jimenez, B . Int. J. Oncol. - 39 (3) : 543-552 (PMID: 21667025) (doi:10.3892/ijo.2011.1074)
13 Apr | 2010 Genome-wide identification of hypoxia-inducible factor binding sites and target genes by a probabilistic model integrating transcription-profiling data and in silico binding site prediction. Ortiz-Barahona, A , Villar, D , Pescador, N , Amigo, J, del Peso, L . Nucleic Acids Res. - 38 (7) : 2332-2345 (PMID: 20061373) (doi:10.1093/nar/gkp1205)
12 Mar | 2010 Hypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1. Pescador, N , Villar, D , Cifuentes, D, Garcia-Rocha, M, Ortiz-Barahona, A , Vazquez, S, Ordoñez, A, Cuevas, Y, Saez-Morales, D, Garcia-Bermejo, ML, Landazuri, MO, Guinovart, J, del Peso, L . PLoS ONE - 5 (3) : e9644 (PMID: 20300197) (doi:10.1371/journal.pone.0009644)
1 Jul | 2009 ERK2, but not ERK1, mediates acquired and "de novo" resistance to imatinib mesylate: implication for CML therapy. Aceves-Luquero, CI, Agarwal, A, Callejas-Valera, JL, Arias-González, L, Esparís-Ogando, A, del Peso Ovalle, L , Bellón-Echeverria, I, de la Cruz-Morcillo, MA, Galán Moya, EM, Moreno Gimeno, I, Gómez, JC, Deininger, MW, Pandiella, A, Sánchez Prieto, R . PLoS ONE - 4 (7) : e6124 (PMID: 19568437) (doi:10.1371/journal.pone.0006124)
10 Apr | 2008 A yeast three-hybrid system that reconstitutes mammalian hypoxia inducible factor regulatory machinery. Alcaide-German, ML , Vara-Vega, A, Garcia-Fernandez, LF , Landazuri, MO, del Peso, L . BMC Cell Biol. - 9 : 18 (PMID: 18402654) (doi:10.1186/1471-2121-9-18)
1 Dec | 2007 Identification of a region on hypoxia-inducible-factor prolyl 4-hydroxylases that determines their specificity for the oxygen degradation domains. Villar, D , Vara-Vega, A, Landázuri, MO, Del Peso, L . Biochem. J. - 408 (2) : 231-240 (PMID: 17725546) (doi:10.1042/BJ20071052)
1 Oct | 2007 Accumulation of hypoxia-inducible factor-1alpha through a novel electrophilic, thiol antioxidant-sensitive mechanism. Olmos, G, Conde, I, Arenas, I, Del Peso, L , Castellanos, C, Landazuri, MO, Lucio-Cazana, J. Cell. Signal. - 19 (10) : 2098-2105 (PMID: 17658243) (doi:10.1016/j.cellsig.2007.06.004)
25 May | 2007 Hypoxia-inducible factors and cancer. Calzada, MJ, del Peso, L . Clin Transl Oncol - 9 (5) : 278-289 (PMID: 17525038)
15 Dec | 2006 Analysis of HIF-prolyl hydroxylases binding to substrates. Landázuri, MO, Vara-Vega, A, Vitón, M, Cuevas, Y, del Peso, L . Biochem. Biophys. Res. Commun. - 351 (2) : 313-320 (PMID: 17069766) (doi:10.1016/j.bbrc.2006.09.170)
15 Aug | 2005 Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene. Pescador, N , Cuevas, Y, Naranjo, S, Alcaide, M , Villar, D , Landázuri, MO, Del Peso, L . Biochem J - 390 (Pt 1) : 189-197 (PMID: 15823097) (doi:10.1042/BJ20042121)
5 Dec | 2003 The von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen. del Peso, L , Castellanos, MC, Temes, E, Martin-Puig, S , Cuevas, Y, Olmos, G, Landazuri, MO. J. Biol. Chem. - 278 (49) : 48690-48695 (PMID: 14506252) (doi:10.1074/jbc.M308862200)
15 Oct | 2003 Specific oncolytic effect of a new hypoxia-inducible factor-dependent replicative adenovirus on von Hippel-Lindau-defective renal cell carcinomas. Cuevas, Y, Hernández-Alcoceba, R, Aragones, J, Naranjo-Suárez, S, Castellanos, MC, Esteban, MA, Martín-Puig, S , Landazuri, MO, del Peso, L . Cancer Res. - 63 (20) : 6877-6884 (PMID: 14583486)
22 Aug | 2003 Down-regulation of hypoxia-inducible factor-2 in PC12 cells by nerve growth factor stimulation. Naranjo-Suárez, S, Castellanos, MC, Alvarez-Tejado, M, Vara, A, Landázuri, MO, del Peso, L . J. Biol. Chem. - 278 (34) : 31895-31901 (PMID: 12805361) (doi:10.1074/jbc.M304079200)
1 Sep | 2002 Modulation of phospholipase D by Ras proteins mediated by its effectors Ral-GDS, PI3K and Raf-1. Lucas, L , Penalva, V , Ramírez de Molina, A , Del Peso, L , Lacal, JC . Int. J. Oncol. - 21 (3) : 477-485 (PMID: 12168089)
19 Apr | 2002 Lack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension. Alvarez-Tejado, M, Alfranca, A, Aragonés, J, Vara, A, Landázuri, MO, del Peso, L . J. Biol. Chem. - 277 (16) : 13508-13517 (PMID: 11815624) (doi:10.1074/jbc.M200017200)
22 Jun | 2001 Hypoxia induces the activation of the phosphatidylinositol 3-kinase/Akt cell survival pathway in PC12 cells: protective role in apoptosis. Alvarez-Tejado, M, Naranjo-Suarez, S, Jiménez, C, Carrera, AC, Landázuri, MO, del Peso, L . J. Biol. Chem. - 276 (25) : 22368-22374 (PMID: 11294857) (doi:10.1074/jbc.M011688200)
8 Sep | 2000 An induced proximity model for NF-kappa B activation in the Nod1/RICK and RIP signaling pathways. Inohara, N, Koseki, T, Lin, J, del Peso, L , Lucas, PC, Chen, FF, Ogura, Y, Núñez, G. J. Biol. Chem. - 275 (36) : 27823-27831 (PMID: 10880512) (doi:10.1074/jbc.M003415200)
1 Sep | 2000 Disruption of the CED-9.CED-4 complex by EGL-1 is a critical step for programmed cell death in Caenorhabditis elegans. del Peso, L , Gonzalez, VM, Inohara, N, Ellis, RE, Núñez, G. J. Biol. Chem. - 275 (35) : 27205-27211 (PMID: 10846174) (doi:10.1074/jbc.M000858200)
20 Jan | 2000 Ras protein is involved in the physiological regulation of phospholipase D by platelet derived growth factor. Lucas, L , del Peso, L , Rodríguez, P, Penalva, V , Lacal, JC . Oncogene - 19 (3) : 431-437 (PMID: 10656691) (doi:10.1038/sj.onc.1203323)
2 Dec | 1999 Regulation of the forkhead transcription factor FKHR, but not the PAX3-FKHR fusion protein, by the serine/threonine kinase Akt. del Peso, L , González, VM, Hernández, R, Barr, FG, Núñez, G. Oncogene - 18 (51) : 7328-7333 (PMID: 10602488) (doi:10.1038/sj.onc.1203159)
21 May | 1999 Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB. Inohara, N, Koseki, T, del Peso, L , Hu, Y, Yee, C, Chen, S, Carrio, R, Merino, J, Liu, D, Ni, J, Núñez, G. J. Biol. Chem. - 274 (21) : 14560-14567 (PMID: 10329646)
11 Dec | 1998 Caenorhabditis elegans EGL-1 disrupts the interaction of CED-9 with CED-4 and promotes CED-3 activation. del Peso, L , González, VM, Núñez, G. J. Biol. Chem. - 273 (50) : 33495-33500 (PMID: 9837929)
8 Oct | 1998 Rho-regulated signals induce apoptosis in vitro and in vivo by a p53-independent, but Bcl2 dependent pathway. Esteve, P , Embade, N , Perona, R , Jiménez, B , del Peso, L , León, J, Arends, M, Miki, T, Lacal, JC . Oncogene - 17 (14) : 1855-1869 (PMID: 9778052) (doi:10.1038/sj.onc.1202082)
15 May | 1998 RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis. Inohara, N, del Peso, L , Koseki, T, Chen, S, Núñez, G. J. Biol. Chem. - 273 (20) : 12296-12300 (PMID: 9575181)
18 Dec | 1997 Rho proteins induce metastatic properties in vivo. del Peso, L , Hernández-Alcoceba, R , Embade, N , Carnero, A, Esteve, P , Paje, C, Lacal, JC . Oncogene - 15 (25) : 3047-3057 (PMID: 9444953) (doi:10.1038/sj.onc.1201499)
24 Oct | 1997 Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. del Peso, L , González-García, M, Page, C, Herrera, R, Nuñez, G. Science - 278 (5338) : 687-689 (PMID: 9381178)
1 Mar | 1997 Activation of phospholipase D by growth factors and oncogenes in murine fibroblasts follow alternative but cross-talking pathways. del Peso, L , Lucas, L , Esteve, P , Lacal, JC . Biochem. J. - 322 ( Pt 2) : 519-528 (PMID: 9065772)
15 Jun | 1996 Activation of phospholipase D by ras proteins is independent of protein kinase C. del Peso, L , Hernández, R, Esteve, P , Lacal, JC . J. Cell. Biochem. - 61 (4) : 599-608 (PMID: 8806084) (doi:10.1002/(SICI)1097-4644(19960616)61:4<599::AID-JCB14>3.0.CO;2-B)
21 Dec | 1995 Induction of apoptosis by rho in NIH 3T3 cells requires two complementary signals. Ceramides function as a progression factor for apoptosis. Esteve, P , del Peso, L , Lacal, JC . Oncogene - 11 (12) : 2657-2665 (PMID: 8545123)
1 Jan | 1995 Generation of phosphorylcholine as an essential event in the activation of Raf-1 and MAP-kinases in growth factors-induced mitogenic stimulation. Jiménez, B , del Peso, L , Montaner, S , Esteve, P , Lacal, JC . J. Cell. Biochem. - 57 (1) : 141-149 (PMID: 7721953) (doi:10.1002/jcb.240570114)
10 May | 1994 Activation of type D phospholipase by serum stimulation and ras-induced transformation in NIH3T3 cells. Carnero, A, Cuadrado, A , del Peso, L , Lacal, JC . Oncogene - 9 (5) : 1387-1395 (PMID: 8152799)