1 Oct | 2022 p73 is required for vessel integrity controlling endothelial junctional dynamics through Angiomotin. Maeso-Alonso, L, Alonso-Olivares, H, Martínez-García, N, López-Ferreras, L, Villoch-Fernández, J, Puente-Santamaría, L , Colas-Algora, N, Fernández-Corona, A, Lorenzo-Marcos, ME, Jiménez, B , Holmgren, L, Wilhelm, M, Millan, J, Del Peso, L , Claesson-Welsh, L, Marques, MM, Marin, MC. Cell Mol Life Sci - 79 (10) : 535 (PMID: 36180740) (doi:10.1007/s00018-022-04560-3)
1 Aug | 2020 Metabolic labeling of RNA uncovers the contribution of transcription and decay rates on hypoxia-induced changes in RNA levels. Tiana, M , Acosta-Iborra, B , Hernández, R , Galiana, C , Fernández-Moreno, MÁ , Jimenez, B , Del Peso, L . RNA - 26 (8) : 1006-1022 (PMID: 32295863) (doi:10.1261/rna.072611.119)
29 Mar | 2020 Hypoxia compensates cell cycle arrest with progenitor differentiation during angiogenesis. Acosta-Iborra, B , Tiana, M , Maeso-Alonso, L, Hernández-Sierra, R , Herranz, G , Santamaria, A , Rey, C , Luna, R , Puente-Santamaria, L , Marques, MM, Marin, MC, Del Peso, L , Jiménez, B . FASEB J. (PMID: 32223018) (doi:10.1096/fj.201903082R)
9 Jan | 2018 The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia. Tiana, M , Acosta-Iborra, B , Puente-Santamaría, L , Hernansanz-Agustin, P , Worsley-Hunt, R, Masson, N, García-Rio, F, Mole, D, Ratcliffe, P, Wasserman, WW, Jimenez, B , Del Peso, L . Nucleic Acids Res. - 46 (1) : 120-133 (PMID: 29059365) (doi:10.1093/nar/gkx951)
12 Sep | 2016 Identification of non-coding genetic variants in samples from hypoxemic respiratory disease patients that affect the transcriptional response to hypoxia. Roche, O , Deguiz, ML, Tiana, M, Galiana-Ribote, C, Martinez-Alcazar, D, Rey-Serra, C, Ranz-Ribeiro, B, Casitas, R, Galera, R, Fernández-Navarro, I, Sánchez-Cuéllar, S, Bernard, V, Ancochea, J, Wasserman, WW, García-Rio, F, Jimenez, B , Del Peso, L . Nucleic Acids Res. (PMID: 27625398) (doi:10.1093/nar/gkw811)
26 Feb | 2016 Melanoma cells block PEDF production in fibroblasts to induce the tumor-promoting phenotype of cancer-associated fibroblasts. Nwani, NG, Deguiz, ML, Jimenez, B , Vinokour, E, Dubrovskyi, O, Ugolkov, A, Mazar, AP, Volpert, OV. Cancer Res. (PMID: 26921338) (doi:10.1158/0008-5472.CAN-15-2468)
23 Sep | 2015 lnc RNAs, hypoxia and metastasis. Jiménez, B , Tiana, M, Del Peso, L . Oncoscience - 2 (10) : 795-796 (PMID: 26682249) (doi:10.18632/oncoscience.247)
1 Jul | 2015 Microphthalmia-Associated Transcription Factor: A Central Regulator of Pigment Epithelium-Derived Factor Controlling Human Melanoma Progression. Jiménez Cuenca, B , Fernández-Barral, A , Orgaz, JL . Am. J. Pathol. - 185 (7) : 2069-2070 (PMID: 26093986) (doi:10.1016/j.ajpath.2015.03.029)
14 May | 2015 EFNA3 long noncoding RNAs induced by hypoxia promote metastatic dissemination. Gómez-Maldonado, L, Tiana, M, Roche, O, Prado-Cabrero, A, Jensen, L, Fernandez-Barral, A, Guijarro-Muñoz, I, Favaro, E, Moreno-Bueno, G , Sanz, L, Aragones, J, Harris, A, Volpert, O, Jimenez, B , del Peso, L . Oncogene - 34 (20) : 2609-2620 (PMID: 25023702) (doi:10.1038/onc.2014.200)
20 Mar | 2015 Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer. Aguilera, Ó, González-Sancho, JM , Zazo, S, Rincón, R, Fernández, AF, Tapia, O, Canals, F, Morte, B , Calvanese, V, Orgaz, JL , Niell, N , Aguilar, S, Freije, JM, Graña, O, Pisano, DG, Borrero, A, Martínez-Useros, J, Jiménez, B , Fraga, MF, García-Foncillas, J, López-Otín, C, Lafarga, M, Rojo, F, Muñoz, A . Oncotarget - 6 (8) : 5903-5917 (PMID: 25788273) (doi:10.18632/oncotarget.3464)
1 Jul | 2014 Increased melanoma formation and dissemination in TyrNRas mice deficient in the tumor suppressor Ing1. Menéndez, C , Adrados, I , Fernández-Barral, A , Jiménez, B , Flores, JM, Cañamero, M, Fuchtbauer, EM, Beermann, F, Palmero, I . Pigment Cell Melanoma Res - 27 (4) : 674-677 (PMID: 24655373) (doi:10.1111/pcmr.12241)
1 Jun | 2014 Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma. Fernández-Barral, A , Orgaz, JL , Baquero, P, Ali, Z, Moreno, A , Tiana, M, Gómez, V, Riveiro-Falkenbach, E, Cañadas, C, Zazo, S, Bertolotto, C, Davidson, I, Rodríguez-Peralto, JL, Palmero, I , Rojo, F, Jensen, LD, del Peso, L , Jiménez, B . Neoplasia - 16 (6) : 529-542 (PMID: 25030625) (doi:10.1016/j.neo.2014.06.001)
1 Apr | 2014 Mad2 and BubR1 modulates tumourigenesis and paclitaxel response in MKN45 gastric cancer cells. Bargiela-Iparraguirre, J , Prado-Marchal, L, Pajuelo-Lozano, N, Jiménez, B , Perona, R , Sánchez-Pérez, I . Cell Cycle - 13 (22) : 3590-3601 (PMID: 25483095) (doi:10.4161/15384101.2014.962952)
10 Jul | 2013 (V600E)BRAF promotes invasiveness of thyroid cancer cells by decreasing E-cadherin expression through a Snail-dependent mechanism. Baquero, P, Sánchez-Hernández, I, Jiménez-Mora, E, Orgaz, JL , Jiménez, B , Chiloeches, A. Cancer Lett. - 335 (1) : 232-241 (PMID: 23435375) (doi:10.1016/j.canlet.2013.02.033)
9 Nov | 2012 Autocrine stimulation of clear-cell renal carcinoma cell migration in hypoxia via HIF-independent suppression of thrombospondin-1. Bienes-Martínez, R, Ordóñez, A, Feijoo-Cuaresma, M, Corral-Escariz, M, Mateo, G, Stenina, O, Jiménez, B , Calzada, MJ. Sci Rep - 2 : 788 (PMID: 23145312) (doi:10.1038/srep00788)
23 Mar | 2012 Hypoxia negatively regulates antimetastatic PEDF in melanoma cells by a hypoxia inducible factor-independent, autophagy dependent mechanism. Fernández-Barral, A , Orgaz, JL , Gomez, V, del Peso, L , Calzada, MJ, Jiménez, B . PLoS ONE - 7 (3) : e32989 (PMID: 22457728) (doi:10.1371/journal.pone.0032989)
1 Sep | 2011 Non-invasive monitoring of hypoxia-inducible factor activation by optical imaging during antiangiogenic treatment in a xenograft model of ovarian carcinoma. Martinez-Poveda, B, Gomez, V, Alcaide-German, M , Perruca, S , Vazquez, S, Alba, LE, Casanovas, O, Garcia-Bermejo, ML, Peso, L , Jimenez, B . Int. J. Oncol. - 39 (3) : 543-552 (PMID: 21667025) (doi:10.3892/ijo.2011.1074)
1 Aug | 2011 Changes in the gene expression profile of A375 human melanoma cells induced by overexpression of multifunctional pigment epithelium-derived factor. Orgaz, JL , Benguria, A, Sanchez-Martinez, C , Ladhani, O, Volpert, OV, Jimenez, B . Melanoma Res. - 21 (4) : 285-297 (PMID: 21673604) (doi:10.1097/CMR.0b013e32834495c3)
13 Jul | 2011 Pigment epithelium-derived factor blocks tumor extravasation by suppressing amoeboid morphology and mesenchymal proteolysis. Ladhani, O, Sánchez-Martinez, C, Orgaz, JL , Jimenez, B , Volpert, OV. Neoplasia - 13 (7) : 633-642 (PMID: 21750657)
10 Feb | 2011 DUSP1/MKP1 promotes angiogenesis, invasion and metastasis in non-small-cell lung cancer. Moncho-Amor, V , Ibañez de Cáceres, I , Bandres, E, Martínez-Poveda, B , Orgaz, JL , Sánchez-Pérez, I , Zazo, S, Rovira, A, Albanell, J, Jiménez, B , Rojo, F, Belda-Iniesta, C , García-Foncillas, J, Perona, R . Oncogene - 30 (6) : 668-678 (PMID: 20890299) (doi:10.1038/onc.2010.449)
16 Nov | 2010 Functional impact of cancer-associated mutations in the tumor suppressor protein ING4. Moreno, A , Palacios, A, Orgaz, JL , Jimenez, B , Blanco, FJ, Palmero, I . Carcinogenesis - 31 (11) : 1932-1938 (PMID: 20705953) (doi:10.1093/carcin/bgq171)
26 Nov | 2009 'Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma'. Orgaz, JL , Ladhani, O, Hoek, KS, Fernández-Barral, A , Mihic, D, Aguilera, O , Seftor, EA, Bernad, A, Rodríguez-Peralto, JL, Hendrix, MJ, Volpert, OV, Jiménez, B . Oncogene - 28 (47) : 4147-4161 (PMID: 19767774) (doi:10.1038/onc.2009.284)
1 Aug | 2008 Following up tumour angiogenesis: from the basic laboratory to the clinic. Orgaz, JL , Martínez-Poveda, B , Fernández-García, NI , Jiménez, B . Clin Transl Oncol - 10 (8) : 468-477 (PMID: 18667377)
24 Jul | 2008 DICKKOPF-4 is induced by TCF/beta-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1alpha,25-dihydroxyvitamin D3. Pendás-Franco, N , García, JM , Peña, C , Valle, N , Pálmer, HG , Heinäniemi, M, Carlberg, C, Jiménez, B , Bonilla, F, Muñoz, A , González-Sancho, JM . Oncogene - 27 (32) : 4467-4477 (PMID: 18408752) (doi:10.1038/onc.2008.88)
1 Jan | 2007 Pigment epithelium-derived factor as a multifunctional antitumor factor. Fernandez-Garcia, NI , Volpert, OV, Jimenez, B . J. Mol. Med. - 85 (1) : 15-22 (PMID: 17106733) (doi:10.1007/s00109-006-0111-z)
29 Sep | 2005 1alpha,25-Dihydroxyvitamin D3 regulates the expression of Id1 and Id2 genes and the angiogenic phenotype of human colon carcinoma cells. Fernandez-Garcia, NI , Palmer, HG , Garcia, M, Gonzalez-Martin, A , del Rio, M, Barettino, D , Volpert, O, Muñoz, A , Jimenez, B . Oncogene - 24 (43) : 6533-6544 (PMID: 16007183) (doi:10.1038/sj.onc.1208801)
15 Aug | 2004 Inhibition of xenografted human melanoma growth and prevention of metastasis development by dual antiangiogenic/antitumor activities of pigment epithelium-derived factor. Garcia, M, Fernandez-Garcia, NI , Rivas, V, Carretero, M, Escamez, MJ, Gonzalez-Martin, A , Medrano, EE, Volpert, O, Jorcano, JL, Jimenez, B , Larcher, F, Del Rio, M. Cancer Res. - 64 (16) : 5632-5642 (PMID: 15313901) (doi:10.1158/0008-5472.CAN-04-0230)
1 Oct | 2003 [Mechanism of inhibition of tumoral angiogenesis by thrombospondin-1]. Jiménez Cuenca, B . Nefrologia - 23 Suppl 3 : 49-53 (PMID: 12901193)
1 Oct | 2002 Glucocorticoid receptor antagonism of AP-1 activity by inhibition of MAPK family. Caelles, C , Bruna, A, Morales, M, González-Sancho, JM , González, MV , Jiménez, B , Muñoz, A . Ernst Schering Res. Found. Workshop (PMID: 12355714)
10 Apr | 2002 Inhibition of tumor growth by systemic treatment with thrombospondin-1 peptide mimetics. Reiher, FK, Volpert, OV, Jimenez, B , Crawford, SE, Dinney, CP, Henkin, J, Haviv, F, Bouck, NP, Campbell, SC. Int. J. Cancer - 98 (5) : 682-689 (PMID: 11920636)
7 Dec | 2001 Mechanistic insights on the inhibition of tumor angiogenesis. Jiménez, B , Volpert, OV. J. Mol. Med. - 78 (12) : 663-672 (PMID: 11434719)
7 Jun | 2001 c-Jun N-terminal kinase activation is required for the inhibition of neovascularization by thrombospondin-1. Jiménez, B , Volpert, OV, Reiher, F, Chang, L, Muñoz, A , Karin, M, Bouck, N. Oncogene - 20 (26) : 3443-3448 (PMID: 11423995) (doi:10.1038/sj.onc.1204464)
4 Sep | 2000 Glucocorticoids antagonize AP-1 by inhibiting the Activation/phosphorylation of JNK without affecting its subcellular distribution. González, MV , Jiménez, B , Berciano, MT, González-Sancho, JM , Caelles, C , Lafarga, M, Muñoz, A . J. Cell Biol. - 150 (5) : 1199-1208 (PMID: 10974006)
1 Jan | 2000 Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1. Jiménez, B , Volpert, OV, Crawford, SE, Febbraio, M, Silverstein, RL, Bouck, N. Nat. Med. - 6 (1) : 41-48 (PMID: 10613822) (doi:10.1038/71517)
8 Oct | 1999 Hormone-activated nuclear receptors inhibit the stimulation of the JNK and ERK signalling pathways in endothelial cells. González, MV , González-Sancho, JM , Caelles, C , Munoz, A , Jiménez, B . FEBS Lett. - 459 (2) : 272-276 (PMID: 10518034)
1 Jun | 1999 Keratinocyte growth factor induces angiogenesis and protects endothelial barrier function. Gillis, P, Savla, U, Volpert, OV, Jimenez, B , Waters, CM, Panos, RJ, Bouck, NP. J. Cell. Sci. - 112 ( Pt 12) : 2049-2057 (PMID: 10341222)
15 Dec | 1998 Multiple forms of angiostatin induce apoptosis in endothelial cells. Lucas, R, Holmgren, L, Garcia, I, Jimenez, B , Mandriota, SJ, Borlat, F, Sim, BK, Wu, Z, Grau, GE, Shing, Y, Soff, GA, Bouck, N, Pepper, MS. Blood - 92 (12) : 4730-4741 (PMID: 9845539)
8 Oct | 1998 Rho-regulated signals induce apoptosis in vitro and in vivo by a p53-independent, but Bcl2 dependent pathway. Esteve, P , Embade, N , Perona, R , Jiménez, B , del Peso, L , León, J, Arends, M, Miki, T, Lacal, JC . Oncogene - 17 (14) : 1855-1869 (PMID: 9778052) (doi:10.1038/sj.onc.1202082)
22 Nov | 1995 Effect of microinjection of rap 2A point mutant proteins on maturation and mottling in Xenopus oocytes. Carnero, A, Jiménez, B . Biochem. Biophys. Res. Commun. - 216 (3) : 748-754 (PMID: 7488189)
1 Jan | 1995 Generation of phosphorylcholine as an essential event in the activation of Raf-1 and MAP-kinases in growth factors-induced mitogenic stimulation. Jiménez, B , del Peso, L , Montaner, S , Esteve, P , Lacal, JC . J. Cell. Biochem. - 57 (1) : 141-149 (PMID: 7721953) (doi:10.1002/jcb.240570114)
1 Aug | 1994 Progesterone but not ras requires MPF for in vivo activation of MAPK and S6 KII: MAPK is an essential conexion point of both signaling pathways. Carnero, A, Jiménez, B , Lacal, JC . J. Cell. Biochem. - 55 (4) : 465-476 (PMID: 7962177) (doi:10.1002/jcb.240550406)
24 Nov | 1993 Phosphorylcholine: a novel second messenger essential for mitogenic activity of growth factors. Cuadrado, A , Carnero, A, Dolfi, F, Jiménez, B , Lacal, JC . Oncogene - 8 (11) : 2959-2968 (PMID: 8414498)
12 Jul | 1993 Localization of rap1 and rap2 proteins in the gelatinase-containing granules of human neutrophils. Mollinedo, F, Perez-Sala, D, Gajate, C, Jimenez, B , Rodriguez, P, Lacal, JC . FEBS Lett. - 326 (1-3) : 209-214 (PMID: 8391995)
24 May | 1993 Tumorigenic activity of rho genes from Aplysia californica. Perona, R , Esteve, P , Jiménez, B , Ballestero, RP, Ramón y Cajal, S, Lacal, JC . Oncogene - 8 (5) : 1285-1292 (PMID: 8479750)
10 Mar | 1993 Chemotactic stimulation of aggregation-stage Dictyostelium cells induces rapid changes in energy metabolism, as measured by succinic thiokinase phosphorylation. Schwandner, WR, Jiménez, B , Schwartz, A, Weijer, CJ, Behrens, M, Mazón, MJ , Fernández-Renart, M . Biochim. Biophys. Acta - 1176 (1-2) : 175-182 (PMID: 8384004)
30 Sep | 1991 Effects of the ras-related rap2 protein on cellular proliferation. Jimenez, B , Pizon, V, Lerosey, I, Béranger, F, Tavitian, A, de Gunzburg, J. Int. J. Cancer - 49 (3) : 471-479 (PMID: 1833345)
1 Jun | 1989 A phospholipid-stimulated protein kinase from Dictyostelium discoideum. Jiménez, B , Pestaña, A , Fernandez-Renart, M. Biochem. J. - 260 (2) : 557-561 (PMID: 2764888)
15 Jan | 1988 Regulation of diacylglycerol kinase in the transition from quiescence to proliferation in Dictyostelium discoideum. Jímenez, B , Van Lookeren Campagne, MM, Pestaña, A , Fernández-Renart, M . Biochem. Biophys. Res. Commun. - 150 (1) : 118-125 (PMID: 2827662)
30 Dec | 1986 Changes in the plasma membrane ATPase activity in relationship to cell proliferation in Dictyostelium. Jímenez, B , Fernandez-Renart, M, Pestaña, A . Biochem. Biophys. Res. Commun. - 141 (3) : 1092-1098 (PMID: 2880581)
15 Sep | 1986 Beta-alanine transport in synaptic plasma membrane vesicles from rat brain. Efflux, exchange and stoichiometry. Agullo, L, Jimenez, B , Aragón, C, Giménez, C. Eur. J. Biochem. - 159 (3) : 611-617 (PMID: 3093232)