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PUBLICACIONES

 

 

spacerTrabajos Publicados por Eva Pérez Guijarro
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  1. Gopalan, V.; Wong, C.W.; Leshem, R.; Owen, L.; Vallius, T.; Shi, Y.; Jiang, Y.; Pérez-Guijarro, E.; Wu, E.; Chin, S.; Ebersole, J.; Smith, C.; Sassano, A.; Constantino, M.A.; Haley, M.J.; Livak, F.; Simpson, R.M.; Day, C.P.; Hurlstone, A.; Hannenhalli, S.; Merlino, G.; Marie, K.L. "Transitory Schwann Cell Precursor and hybrid states underpin melanoma therapy resistance and metastasis.". bioRxiv. (): . (2025). (PMID: 40777322).
    spacer Hdac2, a histone deacetylase associated with this Neural/SCP hybrid state, promotes a mesenchymal-like state switch, remodels the tumor microenvironment, and sensitizes melanoma cells to TNFα and tumors to ICI therapy. Our methodology thus reveals dynamic patterns of lineage state switching correlated with melanoma tumor evolution to drive insight into new therapeutic targets.')" value="Abstract">

  2. Hirsch, M.G.; Pal, S.; Rashidi Mehrabadi, F.; Malikic, S.; Gruen, C.; Sassano, A.; Pérez-Guijarro, E.; Merlino, G.; Sahinalp, S.C.; Molloy, E.K.; Day, C.P.; Przytycka, T.M. "Stochastic modeling of single-cell gene expression adaptation reveals non-genomic contribution to evolution of tumor subclones.". Cell Syst. (): . (2024). (PMID: 39701099).
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  3. Daugherty-Lopès, A.; Pérez-Guijarro, E.; Gopalan, V.; Rappaport, J.; Chen, Q.; Huang, A.; Lam, K.C.; Chin, S.; Ebersole, J.; Wu, E.; Needle, G.A.; Church, I.; Kyriakopoulos, G.; Xie, S.; Zhao, Y.; Gruen, C.; Sassano, A.; Araya, R.E.; Thorkelsson, A.; Smith, C.; Lee, M.P.; Hannenhalli, S.; Day, C.P.; Merlino, G.; Goldszmid, R.S. "IMMUNE AND MOLECULAR CORRELATES OF RESPONSE TO IMMUNOTHERAPY REVEALED BY BRAIN-METASTATIC MELANOMA MODELS.". bioRxiv. (): . (2024). (PMID: 39372744).
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  4. Hirsch, M.G.; Pal, S.; Mehrabadi, F.R.; Malikic, S.; Gruen, C.; Sassano, A.; Pérez-Guijarro, E.; Merlino, G.; Sahinalp, C.; Molloy, E.K.; Day, C.P.; Przytycka, T.M. "Stochastic modelling of single-cell gene expression adaptation reveals non-genomic contribution to evolution of tumor subclones.". bioRxiv. (): . (2024). (PMID: 38712152).
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  5. Alonso-Curbelo, D.; Riveiro-Falkenbach, E.; Pérez-Guijarro, E.; Cifdaloz, M.; Karras, P.; Osterloh, L.; Megías, D.; Cañón, E.; Calvo, T.G.; Olmeda, D.; Gómez-López, G.; Graña, O.; Sánchez-Arévalo Lobo, V.J.; Pisano, D.G.; Wang, H.W.; Ortiz-Romero, P.; Tormo, D.; Hoek, K.; Rodríguez-Peralto, J.L.; Joyce, J.A.; Soengas, M.S. "RAB7 controls melanoma progression by exploiting a lineage-specific wiring of the endolysosomal pathway.". Cancer Cell. 26(1): 61-76. (2014). (PMID: 24981740).
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  6. Tiana, M.; Villar, D.; Pérez-Guijarro, E.; Gómez-Maldonado, L.; Moltó, E.; Fernández-Miñán, A.; Gómez-Skarmeta, J.L.; Montoliu, L.; del Peso, L. "A role for insulator elements in the regulation of gene expression response to hypoxia.". Nucleic Acids Res.. 40(5): 1916-1927. (2012). (PMID: 22067454).
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Instituto de Investigaciones Biomédicas "Alberto Sols"
C/Arturo Duperier 4. 28029 Madrid. (Spain)
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