17 Apr | 2024 ΔNp73 and its effector targets promote colorectal peritoneal carcinosis and predict survival. Pastor-Morate, D , Amigo-Morán, L , Garranzo-Asensio, M, Rejas-González, R, Carnicero, P , Rodríguez, N, Pérez-Robledo, JP, Barderas, R, Prieto-Nieto, I, Domínguez, G . J Pathol (PMID: 38629257) (doi:10.1002/path.6286)
19 May | 2022 In-depth proteomics characterization of ∆Np73 effectors identifies key proteins with diagnostic potential implicated in lymphangiogenesis, vasculogenesis and metastasis in colorectal cancer. Garranzo-Asensio, M, Rodríguez-Cobos, J , Millán, CS , Poves, C, Fernández-Aceñero, MJ, Pastor-Morate, D , Viñal, D, Montero-Calle, A, Solís-Fernández, G, Ceron, MÁ, Gámez-Chiachio, M , Rodríguez, N, Guzmán-Aránguez, A, Barderas, R, Domínguez, G . Mol Oncol (PMID: 35586989) (doi:10.1002/1878-0261.13228)
7 May | 2021 ΔNp73, TAp73 and Δ133p53 Extracellular Vesicle Cargo as Early Diagnosis Markers in Colorectal Cancer. Rodríguez-Cobos, J , Viñal, D, Poves, C, Fernández-Aceñero, MJ, Peinado, H , Pastor-Morate, D , Prieto, MI, Barderas, R, Rodríguez-Salas, N, Domínguez, G . Cancers (Basel) - 13 (9) (PMID: 34066954) (doi:10.3390/cancers13092240)
10 Feb | 2020 Multiplexed monitoring of a novel autoantibody diagnostic signature of colorectal cancer using HaloTag technology-based electrochemical immunosensing platform. Garranzo-Asensio, M, Guzmán-Aránguez, A, Povedano, E, Ruiz-Valdepeñas Montiel, V, Poves, C, Fernandez-Aceñero, MJ, Montero-Calle, A, Solís-Fernández, G, Fernandez-Diez, S, Camps, J, Arenas, M, Rodríguez-Tomàs, E, Joven, J, Sanchez-Martinez, M, Rodriguez, N, Dominguez, G , Yáñez-Sedeño, P, Pingarrón, JM, Campuzano, S, Barderas, R. Theranostics - 10 (7) : 3022-3034 (PMID: 32194852) (doi:10.7150/thno.42507)
24 Jan | 2020 Genomic profiling in oncology clinical practice. Rodríguez, N, Viñal, D, Rodríguez-Cobos, J , De Castro, J, Domínguez, G . Clin Transl Oncol (PMID: 31981077) (doi:10.1007/s12094-020-02296-9)
7 Jan | 2020 Identification of tumor-associated antigens with diagnostic ability of colorectal cancer by in-depth immunomic and seroproteomic analysis. Garranzo-Asensio, M, San Segundo-Acosta, P, Povés, C, Fernández-Aceñero, MJ, Martínez-Useros, J, Montero-Calle, A, Solís-Fernández, G, Sanchez-Martinez, M, Rodríguez, N, Cerón, MÁ, Fernandez-Diez, S, Domínguez, G , de Los Ríos, V, Peláez-García, A, Guzmán-Aránguez, A, Barderas, R. J Proteomics - 214 : 103635 (PMID: 31918032) (doi:10.1016/j.jprot.2020.103635)
1 Oct | 2019 ΔNp73 status in peritoneal and ovarian dissemination of appendicular adenocarcinoids (goblet cells). Prieto-Nieto, MI, Pastor, D, Rodríguez-Cobos, J , Pérez, JP, Méndez, C, Palacios, E, Arranz-Alvarez, M, Santos-López, J , Cano-Vega, M , Viñal, D, Rodríguez, N, Domínguez, G . Clin Transl Oncol - 21 (10) : 1432-1439 (PMID: 31025168) (doi:10.1007/s12094-019-02091-1)
19 Sep | 2019 The specific seroreactivity to ∆Np73 isoforms shows higher diagnostic ability in colorectal cancer patients than the canonical p73 protein. Garranzo-Asensio, M, Guzmán-Aránguez, A, Povés, C, Fernández-Aceñero, MJ, Montero-Calle, A, Ceron, MÁ, Fernandez-Diez, S, Rodríguez, N, Gómez de Cedrón, M, Ramírez de Molina, A , Domínguez, G , Barderas, R. Sci Rep - 9 (1) : 13547 (PMID: 31537884) (doi:10.1038/s41598-019-49960-x)
1 Jul | 2019 ΔNp73 and Δ133p53 in liquid biopsy as early diagnostic markers for colorectal cancer. Rodriguez-Cobos, J , Viñal, D, Poves, C, Fernández-Aceñero, M, Santos-Lopez, J , Carnicero, P, Amor, A, Peinado, H , Barderas, R, Rodríguez-Salas, N, Domínguez, G . Ann. Oncol. - 30 Suppl 4 : iv86-iv87 (PMID: 32085324) (doi:10.1093/annonc/mdz155.314)
17 Oct | 2018 XPA, XPC, and XPD Modulate Sensitivity in Gastric Cisplatin Resistance Cancer Cells. Pajuelo-Lozano, N , Bargiela-Iparraguirre, J , Dominguez, G , Quiroga, AG, Perona, R , Sanchez-Perez, I . Front Pharmacol - 9 : 1197 (PMID: 30386247) (doi:10.3389/fphar.2018.01197)
18 Sep | 2018 Determination of Cadherin-17 in Tumor Tissues of Different Metastatic Grade Using a Single Incubation-Step Amperometric Immunosensor. Valverde, A, Povedano, E, Ruiz-Valdepeñas Montiel, V, Yáñez-Sedeño, P, Garranzo-Asensio, M, Rodríguez, N, Domínguez, G , Barderas, R, Campuzano, S, Pingarrón, JM. Anal. Chem. - 90 (18) : 11161-11167 (PMID: 30134108) (doi:10.1021/acs.analchem.8b03506)
11 Dec | 2017 Clinical implications of the deregulated TP73 isoforms expression in cancer. Rodríguez, N, Peláez, A, Barderas, R, Domínguez, G . Clin Transl Oncol (PMID: 29230693) (doi:10.1007/s12094-017-1802-3)
5 Jan | 2017 Clinical relevance of colorectal cancer molecular subtypes. Rodriguez-Salas, N, Dominguez, G , Barderas, R, Mendiola, M , García-Albéniz, X, Maurel, J, Batlle, JF. Crit. Rev. Oncol. Hematol. - 109 : 9-19 (PMID: 28010901) (doi:10.1016/j.critrevonc.2016.11.007)
20 Dec | 2016 Toward Liquid Biopsy: Determination of the Humoral Immune Response in Cancer Patients Using HaloTag Fusion Protein-Modified Electrochemical Bioplatforms. Garranzo-Asensio, M, Guzman-Aranguez, A, Povés, C, Fernández-Aceñero, MJ, Torrente-Rodríguez, RM, Ruiz-Valdepeñas Montiel, V, Domínguez, G , Frutos, LS, Rodríguez, N, Villalba, M, Pingarrón, JM, Campuzano, S, Barderas, R. Anal. Chem. - 88 (24) : 12339-12345 (PMID: 28193070) (doi:10.1021/acs.analchem.6b03526)
1 Oct | 2015 β-Cryptoxanthin Synergistically Enhances the Antitumoral Activity of Oxaliplatin through ΔNP73 Negative Regulation in Colon Cancer. San Millán, C, Soldevilla, B, Martín, P, Gil-Calderón, B, Compte, M, Pérez-Sacristán, B, Donoso, E, Peña, C , Romero, J, Granado-Lorencio, F, Bonilla, F, Domínguez, G . Clin. Cancer Res. - 21 (19) : 4398-4409 (PMID: 26023082) (doi:10.1158/1078-0432.CCR-14-2027)
1 Sep | 2014 Different exosome cargo from plasma/bronchoalveolar lavage in non-small-cell lung cancer. Rodríguez, M, Silva, J, López-Alfonso, A, López-Muñiz, MB, Peña, C , Domínguez, G , García, JM, López-Gónzalez, A, Méndez, M, Provencio, M, García, V, Bonilla, F. Genes Chromosomes Cancer - 53 (9) : 713-724 (PMID: 24764226) (doi:10.1002/gcc.22181)
1 Apr | 2013 Cancer-associated fibroblast and M2 macrophage markers together predict outcome in colorectal cancer patients. Herrera, M, Herrera, A, Domínguez, G , Silva, J, García, V, García, JM, Gómez, I, Soldevilla, B, Muñoz, C, Provencio, M, Campos-Martin, Y, García de Herreros, A, Casal, I, Bonilla, F, Peña, C . Cancer Sci - 104 (4) : 437-444 (PMID: 23298232) (doi:10.1111/cas.12096)
15 Sep | 2011 Prognostic impact of ΔTAp73 isoform levels and their target genes in colon cancer patients. Soldevilla, B, Díaz, R, Silva, J, Campos-Martín, Y, Muñoz, C, García, V, García, JM, Peña, C , Herrera, M, Rodriguez, M, Gómez, I, Mohamed, N, Marques, MM, Bonilla, F, Domínguez, G . Clin Cancer Res - 17 (18) : 6029-6039 (PMID: 21807636) (doi:10.1158/1078-0432.CCR-10-2388)
28 Mar | 2011 TWIST1 is expressed in colorectal carcinomas and predicts patient survival. Gomez, I, Peña, C , Herrera, M, Muñoz, C, Larriba, MJ , Garcia, V, Dominguez, G , Silva, J, Rodriguez, R, Garcia de Herreros, A, Bonilla, F, Garcia, JM. PLoS ONE - 6 (3) : e18023 (PMID: 21464926) (doi:10.1371/journal.pone.0018023)
1 Mar | 2011 Vesicle-related microRNAs in plasma of nonsmall cell lung cancer patients and correlation with survival. Silva, J, García, V, Zaballos, Á, Provencio, M, Lombardía, L, Almonacid, L, García, JM , Domínguez, G , Peña, C , Diaz, R, Herrera, M, Varela, A, Bonilla, F. Eur Respir J - 37 (3) : 617-623 (PMID: 20595154) (doi:10.1183/09031936.00029610)
1 Dec | 2010 Differential regulation of TP73 isoforms by 1α,25-dihydroxyvitamin D3 and survivin in human colon and breast carcinomas. Díaz, R, González-Sancho, JM , Soldevilla, B, Silva, J, García, JM, García, V, Peña, C , Herrera, M, Gómez, I, Bonilla, F, Domínguez, G . Genes Chromosomes Cancer - 49 (12) : 1135-1142 (PMID: 20842728) (doi:10.1002/gcc.20821)
15 Dec | 2009 Extracellular tumor-related mRNA in plasma of lymphoma patients and survival implications. Garcia, V, Garcia, JM, Silva, J, Martin, P, Peña, C , Dominguez, G , Diaz, R, Herrera, M, Maximiano, C, Sabin, P, Rueda, A, Cruz, MA, Rodriguez, J, Canales, MA, Bonilla, F, Provencio, M. PLoS One - 4 (12) : e8173 (PMID: 20016842) (doi:10.1371/journal.pone.0008173)
10 Dec | 2009 SNAI1 expression in colon cancer related with CDH1 and VDR downregulation in normal adjacent tissue. Peña, C , García, JM , Larriba, MJ , Barderas, R, Gómez, I, Herrera, M, García, V, Silva, J, Domínguez, G , Rodríguez, R, Cuevas, J, de Herreros, AG, Casal, JI, Muñoz, A , Bonilla, F. Oncogene - 28 (49) : 4375-4385 (PMID: 19802011) (doi:10.1038/onc.2009.285)
1 Sep | 2009 Differences in repair of DNA cross-links between lymphocytes and epithelial tumor cells from colon cancer patients measured in vitro with the comet assay. Herrera, M, Dominguez, G , Garcia, JM, Peña, C , Jimenez, C, Silva, J, Garcia, V, Gomez, I, Diaz, R, Martin, P, Bonilla, F. Clin Cancer Res - 15 (17) : 5466-5472 (PMID: 19690199) (doi:10.1158/1078-0432.CCR-08-3268)
1 Aug | 2009 Differential genetic and functional markers of second neoplasias in Hodgkin's disease patients. Lorenzo, Y, Provencio, M, Lombardía, L, Díaz, R, Silva, J, Herrera, M, García, JM, Peña, C , García, V, Romero, J, Domínguez, G , Bonilla, F. Clin Cancer Res - 15 (15) : 4823-4828 (PMID: 19622580) (doi:10.1158/1078-0432.CCR-08-3224)
1 Nov | 2008 Levels of VEGF-A mRNA in plasma from patients with colorectal carcinoma as possible surrogate marker of angiogenesis. Garcia, V, Garcia, JM, Silva, J, Peña, C , Dominguez, G , Lorenzo, Y, Diaz, R, Alonso, I, Colas, A, Hurtado, A, Sanchez, A, Bonilla, F. J Cancer Res Clin Oncol - 134 (11) : 1165-1171 (PMID: 18461364) (doi:10.1007/s00432-008-0405-3)
1 Sep | 2008 Deregulated expression of miR-106a predicts survival in human colon cancer patients. Díaz, R, Silva, J, García, JM, Lorenzo, Y, García, V, Peña, C , Rodríguez, R, Muñoz, C, García, F, Bonilla, F, Domínguez, G . Genes Chromosomes Cancer - 47 (9) : 794-802 (PMID: 18521848) (doi:10.1002/gcc.20580)
1 Sep | 2008 p73 Isoforms affect VEGF, VEGF165b and PEDF expression in human colorectal tumors: VEGF165b downregulation as a marker of poor prognosis. Díaz, R, Peña, C , Silva, J, Lorenzo, Y, García, V, García, JM, Sánchez, A, Espinosa, P, Yuste, R, Bonilla, F, Domínguez, G . Int J Cancer - 123 (5) : 1060-1067 (PMID: 18546269) (doi:10.1002/ijc.23619)
10 Jul | 2008 Extracellular plasma RNA from colon cancer patients is confined in a vesicle-like structure and is mRNA-enriched. García, JM, García, V, Peña, C , Domínguez, G , Silva, J, Diaz, R, Espinosa, P, Citores, MJ, Collado, M, Bonilla, F. RNA - 14 (7) : 1424-1432 (PMID: 18456845) (doi:10.1261/rna.755908)
18 May | 2008 Free circulating mRNA in plasma from breast cancer patients and clinical outcome. García, V, García, JM, Peña, C , Silva, J, Domínguez, G , Lorenzo, Y, Diaz, R, Espinosa, P, de Sola, JG, Cantos, B, Bonilla, F. Cancer Lett - 263 (2) : 312-320 (PMID: 18280643) (doi:10.1016/j.canlet.2008.01.008)
1 Dec | 2007 Circulating Bmi-1 mRNA as a possible prognostic factor for advanced breast cancer patients. Silva, J, García, V, García, JM, Peña, C , Domínguez, G , Díaz, R, Lorenzo, Y, Hurtado, A, Sánchez, A, Bonilla, F. Breast Cancer Res - 9 (4) : R55 (PMID: 17711569) (doi:10.1186/bcr1760)
1 Nov | 2007 Prognostic value of LISCH7 mRNA in plasma and tumor of colon cancer patients. García, JM, Peña, C , García, V, Domínguez, G , Muñoz, C, Silva, J, Millán, I, Diaz, R, Lorenzo, Y, Rodriguez, R, Bonilla, F. Clin Cancer Res - 13 (21) : 6351-6358 (PMID: 17975147) (doi:10.1158/1078-0432.CCR-07-0882)
1 Dec | 2006 Implication of polycomb members Bmi-1, Mel-18, and Hpc-2 in the regulation of p16INK4a, p14ARF, h-TERT, and c-Myc expression in primary breast carcinomas. Silva, J, García, JM, Peña, C , García, V, Domínguez, G , Suárez, D, Camacho, FI, Espinosa, R, Provencio, M, España, P, Bonilla, F. Clin Cancer Res - 12 (23) : 6929-6936 (PMID: 17145810) (doi:10.1158/1078-0432.CCR-06-0788)
1 Dec | 2006 The presence of an intronic deletion in p73 and high levels of ZEB1 alter the TAp73/DeltaTAp73 ratio in colorectal carcinomas. Domínguez, G , Peña, C , Silva, J, García, JM , García, V, Rodríguez, R, Cantos, B, Citores, MJ, España, P, Bonilla, F. J Pathol - 210 (4) : 390-397 (PMID: 17029218) (doi:10.1002/path.2066)
1 Nov | 2006 The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E-cadherin and vitamin D receptor in human colon carcinomas. Peña, C , García, JM, García, V, Silva, J, Domínguez, G , Rodríguez, R, Maximiano, C, García de Herreros, A, Muñoz, A , Bonilla, F. Int. J. Cancer - 119 (9) : 2098-2104 (PMID: 16804902) (doi:10.1002/ijc.22083)
21 Jul | 2006 Extracellular tumor DNA in plasma and overall survival in breast cancer patients. Garcia, JM, Garcia, V, Silva, J, Peña, C , Dominguez, G , Sanchez, A, Sanfrutos, L, Provencio, M, Millan, I, Chaparro, D, España, P, Bonilla, F. Genes Chromosomes Cancer - 45 (7) : 692-701 (PMID: 16607614) (doi:10.1002/gcc.20334)
1 Apr | 2006 Thymidylate synthase messenger RNA expression in plasma from patients with colon cancer: prognostic potential. Garcia, V, García, JM, Peña, C , Silva, J, Domínguez, G , Hurtado, A, Alonso, I, Rodriguez, R, Provencio, M, Bonilla, F. Clin Cancer Res - 12 (7 Pt 1) : 2095-2100 (PMID: 16609021) (doi:10.1158/1078-0432.CCR-05-1644)
22 Feb | 2006 Analysis of the candidate tumor suppressor Ris-1 in primary human breast carcinomas. Silva, J, Silva, JM, Barradas, M, García, JM, Domínguez, G , García, V, Peña, C , Gallego, I, Espinosa, R, Serrano, M, Bonilla, F. Mutat Res - 594 (1-2) : 78-85 (PMID: 16280139) (doi:10.1016/j.mrfmmm.2005.07.017)
10 Feb | 2006 DeltaTAp73 upregulation correlates with poor prognosis in human tumors: putative in vivo network involving p73 isoforms, p53, and E2F-1. Domínguez, G , García, JM, Peña, C , Silva, J, García, V, Martínez, L, Maximiano, C, Gómez, ME, Rivera, JA, García-Andrade, C, Bonilla, F. J Clin Oncol - 24 (5) : 805-815 (PMID: 16380414) (doi:10.1200/JCO.2005.02.2350)
17 May | 2005 The GADD45, ZBRK1 and BRCA1 pathway: quantitative analysis of mRNA expression in colon carcinomas. Garcia, V, García, JM, Peña, C , Silva, J, Domínguez, G , Rodríguez, R, Maximiano, C, Espinosa, R, España, P, Bonilla, F. J Pathol - 206 (1) : 92-99 (PMID: 15772983) (doi:10.1002/path.1751)
4 Oct | 2004 Overexpression of p16INK4a correlates with high expression of p73 in breast carcinomas. Garcia, V, Silva, J, Dominguez, G , García, JM, Peña, C , Rodriguez, R, Provencio, M, España, P, Bonilla, F. Mutat Res - 554 (1-2) : 215-221 (PMID: 15450420) (doi:10.1016/j.mrfmmm.2004.04.008)
16 Mar | 2004 Intronic deletion affecting a negative regulatory region of TP73 is related to breast and colorectal carcinomas. Peña, C , Garcia, JM, Dominguez, G , Silva, J, Garcia, V, Carcereny, E, Vargas, J, Provencio, M, España, P, Bonilla, F. Genes Chromosomes Cancer - 39 (3) : 257-262 (PMID: 14732927) (doi:10.1002/gcc.10322)
1 Feb | 2004 Altered expression of the ZBRK1 gene in human breast carcinomas. Garcia, V, Domínguez, G , García, JM, Silva, J, Peña, C , Silva, JM, Carcereny, E, Menendez, J, España, P, Bonilla, F. J Pathol - 202 (2) : 224-232 (PMID: 14743505) (doi:10.1002/path.1513)
20 Jun | 2002 Expression of thyroid hormone receptor/erbA genes is altered in human breast cancer. Silva, JM, Domínguez, G , González-Sancho, JM , García, JM, Silva, J, García-Andrade, C, Navarro, A, Muñoz, A , Bonilla, F. Oncogene - 21 (27) : 4307-4316 (PMID: 12082618) (doi:10.1038/sj.onc.1205534)