Publications

All our publications

*Listed are the articles found in the PubMed database.

Publications by “Pilar Santisteban Sanz”

Focal adhesion kinase-YAP signaling axis drives drug-tolerant persister cells and residual disease in lung cancer.

Haderk, F, Chou, YT, Cech, L, Fernández-Méndez, C , Yu, J, Olivas, V, Meraz, IM, Barbosa Rabago, D, Kerr, DL, Gomez, C, Allegakoen, DV, Guan, J, Shah, KN, Herrington, KA, Gbenedio, OM, Nanjo, S, Majidi, M, Tamaki, W, Pourmoghadam, YK, Rotow, JK, McCoach, CE, Riess, JW, Gutkind, JS, Tang, TT, Post, L, Huang, B, Santisteban, P , Goodarzi, H, Bandyopadhyay, S, Kuo, CJ, Roose, JP, Wu, W, Blakely, CM, Roth, JA, Bivona, TG.

BRAF V600E Status Sharply Differentiates Lymph Node Metastasis-associated Mortality Risk in Papillary Thyroid Cancer.

Tao, Y, Wang, F, Shen, X, Zhu, G, Liu, R, Viola, D , Elisei, R, Puxeddu, E, Fugazzola, L, Colombo, C, Jarzab, B, Czarniecka, A, Lam, AK, Mian, C, Vianello, F, Yip, L, Riesco-Eizaguirre, G , Santisteban, P , O'Neill, CJ, Sywak, MS, Clifton-Bligh, R, Bendlova, B, Sýkorová, V, Zhao, S, Wang, Y, Xing, M.

A Novel Role for the Tumor Suppressor Gene ITF2 in Tumorigenesis and Chemotherapy Response.

Pernía, O, Sastre-Perona, A , Rodriguez-Antolín, C, García-Guede, A, Palomares-Bralo, M, Rosas, R, Sanchez-Cabrero, D, Cruz, P, Rodriguez, C, Diestro, M, Martín-Arenas, R, Pulido, V, Santisteban, P , Castro, J, Vera, O, Cáceres, II.

BRAF V600E status may facilitate decision-making on active surveillance of low-risk papillary thyroid microcarcinoma.

Kim, KJ, Kim, SG, Tan, J, Shen, X, Viola, D , Elisei, R, Puxeddu, E, Fugazzola, L, Colombo, C, Jarzab, B, Czarniecka, A, Lam, AK, Mian, C, Vianello, F, Yip, L, Riesco-Eizaguirre, G , Santisteban, P , O'Neill, CJ, Sywak, MS, Clifton-Bligh, R, Bendlova, B, Sýkorová, V, Xing, M.

BRAF V600E Confers Male Sex Disease-Specific Mortality Risk in Patients With Papillary Thyroid Cancer.

Wang, F, Zhao, S, Shen, X, Zhu, G, Liu, R, Viola, D , Elisei, R, Puxeddu, E, Fugazzola, L, Colombo, C, Jarzab, B, Czarniecka, A, Lam, AK, Mian, C, Vianello, F, Yip, L, Riesco-Eizaguirre, G , Santisteban, P , O'Neill, CJ, Sywak, MS, Clifton-Bligh, R, Bendlova, B, Sýkorová, V, Wang, Y, Xing, M.

The NFE2-related transcription factor 2 (Nrf2) coordinates antioxidant defense with thyroglobulin production and iodination in the thyroid gland.

Ziros, PG, Habeos, I, Chartoumpekis, DV, Ntalampyra, E, Somm, E, Renaud, CO, Bongiovanni, M, Trougakos, IP, Yamamoto, M, Kensler, TW, Santisteban, P , Carrasco, N, Ris-Stalpers, C, Amendola, E, Liao, XH, Rossich, L, Thomasz, L, Juvenal, GJ, Refetoff, S , Sykiotis, GP.

Functional Toll-like Receptor 4 Overexpression in Papillary Thyroid Cancer by MAPK/ERK-Induced ETS1 Transcriptional Activity.

Peyret, V, Nazar, M, Martín, M, Quintar, AA, Fernandez, EA, Geysels, RC, Fuziwara, CS, Montesinos, MM, Maldonado, CA, Santisteban, P , Kimura, ET, Pellizas, CG, Nicola, JP, Masini-Repiso, AM.

BRAF V600E Mutation-Assisted Risk Stratification of Solitary Intrathyroidal Papillary Thyroid Cancer for Precision Treatment.

Huang, Y, Qu, S, Zhu, G, Wang, F, Liu, R, Shen, X, Viola, D , Elisei, R, Puxeddu, E, Fugazzola, L, Colombo, C, Jarzab, B, Czarniecka, A, Lam, AK, Mian, C, Vianello, F, Yip, L, Riesco-Eizaguirre, G , Santisteban, P , O'Neill, CJ, Sywak, MS, Clifton-Bligh, R, Bendlova, B, Sýkorová, V, Xing, M.

Patient Age-Associated Mortality Risk Is Differentiated by BRAF V600E Status in Papillary Thyroid Cancer.

Shen, X, Zhu, G, Liu, R, Viola, D , Elisei, R, Puxeddu, E, Fugazzola, L, Colombo, C, Jarzab, B, Czarniecka, A, Lam, AK, Mian, C, Vianello, F, Yip, L, Riesco-Eizaguirre, G , Santisteban, P , O'Neill, CJ, Sywak, MS, Clifton-Bligh, R, Bendlova, B, Sýkorová, V, Xing, M.

The Prognostic Value of Tumor Multifocality in Clinical Outcomes of Papillary Thyroid Cancer.

Wang, F, Yu, X, Shen, X, Zhu, G, Huang, Y, Liu, R, Viola, D , Elisei, R, Puxeddu, E, Fugazzola, L, Colombo, C, Jarzab, B, Czarniecka, A, Lam, AK, Mian, C, Vianello, F, Yip, L, Riesco-Eizaguirre, G , Santisteban, P , O'Neill, CJ, Sywak, MS, Clifton-Bligh, R, Bendlova, B, Sýkorová, V, Wang, Y, Liu, S, Zhao, J, Zhao, S, Xing, M.

Thyroid cancer GWAS identifies 10q26.12 and 6q14.1 as novel susceptibility loci and reveals genetic heterogeneity among populations.

Mancikova, V, Cruz, R, Inglada-Pérez, L, Fernández-Rozadilla, C, Landa, I, Cameselle-Teijeiro, J, Celeiro, C, Pastor, S, Velázquez, A, Marcos, R, Andía, V, Álvarez-Escolá, C, Meoro, A, Schiavi, F, Opocher, G, Quintela, I, Ansede-Bermejo, J, Ruiz-Ponte, C, Santisteban, P , Robledo, M, Carracedo, A.

Activation of the GLP-1 Receptor by Liraglutide Increases ACE2 Expression, Reversing Right Ventricle Hypertrophy, and Improving the Production of SP-A and SP-B in the Lungs of Type 1 Diabetes Rats.

Romaní-Pérez, M, Outeiriño-Iglesias, V, Moya, CM , Santisteban, P , González-Matías, LC, Vigo, E, Mallo, F.

MicroRNA deep-sequencing reveals master regulators of follicular and papillary thyroid tumors.

Mancikova, V, Castelblanco, E, Pineiro-Yanez, E, Perales-Paton, J, de Cubas, AA, Inglada-Perez, L, Matias-Guiu, X, Capel, I, Bella, M, Lerma, E, Riesco-Eizaguirre, G , Santisteban, P , Maravall, F, Mauricio, D, Al-Shahrour, F, Robledo, M.

Association between BRAF V600E mutation and recurrence of papillary thyroid cancer.

Xing, M, Alzahrani, AS, Carson, KA, Shong, YK, Kim, TY, Viola, D , Elisei, R, Bendlová, B, Yip, L, Mian, C, Vianello, F, Tuttle, RM, Robenshtok, E, Fagin, JA, Puxeddu, E, Fugazzola, L, Czarniecka, A, Jarzab, B, O'Neill, CJ, Sywak, MS, Lam, AK, Riesco-Eizaguirre, G , Santisteban, P , Nakayama, H, Clifton-Bligh, R, Tallini, G, Holt, EH, Sýkorová, V.

DNA methylation signatures identify biologically distinct thyroid cancer subtypes.

Rodríguez-Rodero, S, Fernández, AF, Fernández-Morera, JL, Castro-Santos, P, Bayon, GF, Ferrero, C, Urdinguio, RG, Gonzalez-Marquez, R, Suarez, C, Fernández-Vega, I, Fresno Forcelledo, MF, Martínez-Camblor, P, Mancikova, V, Castelblanco, E, Perez, M, Marrón, PI, Mendiola, M , Hardisson, D, Santisteban, P , Riesco-Eizaguirre, G , Matías-Guiu, X, Carnero, A, Robledo, M, Delgado-Álvarez, E, Menéndez-Torre, E, Fraga, MF.

Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer.

Xing, M, Alzahrani, AS, Carson, KA, Viola, D , Elisei, R, Bendlova, B, Yip, L, Mian, C, Vianello, F, Tuttle, RM, Robenshtok, E, Fagin, JA, Puxeddu, E, Fugazzola, L, Czarniecka, A, Jarzab, B, O'Neill, CJ, Sywak, MS, Lam, AK, Riesco-Eizaguirre, G , Santisteban, P , Nakayama, H, Tufano, RP, Pai, SI, Zeiger, MA, Westra, WH, Clark, DP, Clifton-Bligh, R, Sidransky, D, Ladenson, PW, Sykorova, V.

The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.

Landa, I, Ruiz-Llorente, S , Montero-Conde, C , Inglada-Pérez, L, Schiavi, F, Leskelä, S, Pita, G, Milne, R, Maravall, J, Ramos, I, Andía, V, Rodríguez-Poyo, P, Jara-Albarrán, A, Meoro, A, del Peso, C, Arribas, L, Iglesias, P, Caballero, J, Serrano, J, Picó, A, Pomares, F, Giménez, G, López-Mondéjar, P, Castello, R, Merante-Boschin, I, Pelizzo, MR, Mauricio, D, Opocher, G, Rodríguez-Antona, C , González-Neira, A, Matías-Guiu, X, Santisteban, P , Robledo, M.

Association study of 69 genes in the ret pathway identifies low-penetrance loci in sporadic medullary thyroid carcinoma.

Ruiz-Llorente, S , Montero-Conde, C , Milne, RL, Moya, CM , Cebrián, A , Letón, R, Cascón, A, Mercadillo, F, Landa, I, Borrego, S, Pérez de Nanclares, G, Alvarez-Escolá, C, Díaz-Pérez, JA, Carracedo, A, Urioste, M, González-Neira, A, Benítez, J, Santisteban, P , Dopazo, J, Ponder, BA, Robledo, M, , .

Bacterial lipopolysaccharide stimulates the thyrotropin-dependent thyroglobulin gene expression at the transcriptional level by involving the transcription factors thyroid transcription factor-1 and paired box domain transcription factor 8.

Vélez, ML , Costamagna, E , Kimura, ET, Fozzatti, L, Pellizas, CG, Montesinos, MM, Lucero, AM, Coleoni, AH, Santisteban, P , Masini-Repiso, AM.

Functional study of a novel single deletion in the TITF1/NKX2.1 homeobox gene that produces congenital hypothyroidism and benign chorea but not pulmonary distress.

Moya, CM , Perez de Nanclares, G, Castaño, L, Potau, N, Bilbao, JR, Carrascosa, A, Bargadá, M, Coya, R, Martul, P, Vicens-Calvet, E, Santisteban, P .

Mutation at position -132 in the islet amyloid polypeptide ( IAPP) gene promoter enhances basal transcriptional activity through a new CRE-like binding site.

Novials, A, Mato, E, Lucas, M, Franco, C, Rivas, M, Santisteban, P , Gomis, R.

Somatostatin interferes with thyrotropin-induced G1-S transition mediated by cAMP-dependent protein kinase and phosphatidylinositol 3-kinase. Involvement of RhoA and cyclin E x cyclin-dependent kinase 2 complexes.

Medina, DL , Toro, MJ, Santisteban, P .

Role of insulin and serum on thyrotropin regulation of thyroid transcription factor-1 and pax-8 genes expression in FRTL-5 thyroid cells.

Medina, DL , Suzuki, K, Pietrarelli, M, Okajima, F, Kohn, LD, Santisteban, P .

Hexachlorobenzene, a dioxin-type compound, increases malic enzyme gene transcription through a mechanism involving the thyroid hormone response element.

Loaiza-Pérez, AI, Seisdedos, MT , Kleiman de Pisarev, DL, Sancovich, HA, Randi, AS, Ferramola de Sancovich, AM, Santisteban, P .

Hexachlorobenzene, a Dioxin-Type Compound, Increases Malic Enzyme Gene Transcription through a Mechanism Involving the Thyroid Hormone Response Element1.

Loaiza-Pe Rez, AI, Seisdedos, MT, Kleiman de Pisarev, DL, Sancovich, HA, Randi, AS, Ferramola de Sancovich, AM, Santisteban, P .

Norepinephrine, tri-iodothyronine and insulin upregulate glyceraldehyde-3-phosphate dehydrogenase mRNA during Brown adipocyte differentiation.

Barroso, I , Benito, B, Garcí-Jiménez, C, Hernández, A, Obregón, MJ , Santisteban, P .

Lung hypoplasia caused by nitrofen is mediated by down-regulation of thyroid transcription factor TTF-1.

Losada, A , Xia, H, Migliazza, L, Diez-Pardo, JA, Santisteban, P , Tovar, JA.

Insulin-induced early growth response gene (Egr-1) mediates a short term repression of rat malic enzyme gene transcription.

Barroso, I , Santisteban, P .

The interaction between the forkhead thyroid transcription factor TTF-2 and the constitutive factor CTF/NF-1 is required for efficient hormonal regulation of the thyroperoxidase gene transcription.

Ortiz, L , Aza-Blanc, P, Zannini, M, Cato, AC, Santisteban, P .

Thyroid-specific gene expression in the multi-step process of thyroid carcinogenesis.

Ros, P, Rossi, DL, Acebrón, A, Santisteban, P .

Circannual somatostatin gene and somatostatin receptor gene expression in the early post-natal rat pineal gland.

Mato, E, Santisteban, P , Chowen, JA, Fornas, O, Bouwens, M, Puig-Domingo, M, Argente, J, Webb, SM.

Transcriptional control of the forkhead thyroid transcription factor TTF-2 by thyrotropin, insulin, and insulin-like growth factor I.

Ortiz, L , Zannini, M, Di Lauro, R, Santisteban, P .

Identification and quantitation of iodotyrosines and iodothyronines in proteins using high-performance liquid chromatography by photodiode-array ultraviolet-visible detection.

de la Vieja, A , Calero, M, Santisteban, P , Lamas, L.

Amino Acid Composition of Proteins Extracted from Endemic Goiter Glands.

Baggio, MC, Medeiros-Neto, G, Osawa, Y, Nguyen, NY, Santisteban, P , Knobel, M, Groliman, EE.

Mapping and functional role of phosphorylation sites in the thyroid transcription factor-1 (TTF-1).

Zannini, M, Acebron, A, De Felice, M, Arnone, MI, Martin-Pérez, J , Santisteban, P , Di Lauro, R.

Function of the homeo and paired domain proteins TTF-1 and Pax-8 in thyroid cell proliferation.

Rossi, DL, Acebrón, A, Santisteban, P .

Comparative effects of food restriction, fasting, diabetes and thyroidectomy on growth hormone and thyrotropin gene expression in the rat pituitary.

Rodríguez, M , Rodríguez, F, Jolin, T, Santisteban, P .

Expression of somatostatin in rat pineal cells in culture.

Mato, E, Santisteban, P , Viader, M, Capellá, G, Fornas, O, Puig-Domingo, M, Webb, SM.

Sequence and chromosomal assignment of a novel cDNA identified by immunoscreening of a thyroid expression library: similarity to a family of mitochondrial solute carrier proteins.

Zarrilli, R, Oates, EL, McBride, OW, Lerman, MI, Chan, JY, Santisteban, P , Ursini, MV, Notkins, AL, Kohn, LD.

Subcellular localization of iodinated thyroid tubulin.

Hargreaves, AJ, Lamas, L, Santisteban, P , Avila, J.

Cloning and characterization of a cDNA that encodes a 70-kDa novel human thyroid autoantigen.

Chan, JY, Lerman, MI, Prabhakar, BS, Isozaki, O, Santisteban, P , Kuppers, RC, Oates, EL, Notkins, AL, Kohn, LD.

Insulin and insulin-like growth factor-I (IGF-I) regulate differentiation as well as growth in FRTL-5 cells.

Isozaki, O, Santisteban, P , Chan, J, Grollman, E, Kohn, L.

TSH and biogenic amine signals in the regulation of thyroid function: independent regulation by protein kinase C and G proteins.

Grollman, EF, Bone, E, Chan, J, Corda, D, Isozaki, O, Marcocci, C, Santisteban, P , Kohn, LD.

TSH receptor structure.

Chan, J, Santisteban, P , De Luca, M, Isozaki, O, Grollman, E, Kohn, L.

Characterization of phosphate residues on thyroglobulin.

Consiglio, E, Acquaviva, AM, Formisano, S, Liguoro, D, Gallo, A, Vittorio, T, Santisteban, P , De Luca, M, Shifrin, S, Yeh, HJ.

Norepinephrine and thyrotropin stimulation of iodide efflux in FRTL-5 thyroid cells involves metabolites of arachidonic acid and is associated with the iodination of thyroglobulin.

Marcocci, C, Luini, A, Santisteban, P , Grollman, EF.

Thyroglobulin gene expression is regulated by insulin and insulin-like growth factor I, as well as thyrotropin, in FRTL-5 thyroid cells.

Santisteban, P , Kohn, LD, Di Lauro, R.

Monoclonal antibody studies defining the origin and properties of autoantibodies in Graves' disease.

Kohn, LD, Alvarez, F, Marcocci, C, Kohn, AD, Corda, D, Hoffman, WE, Tombaccini, D, Valente, WA, de Luca, M, Santisteban, P .

The effect of varying iodine content on the proteolytic activity of rat thyroid lysosomes.

Santisteban, P , Lamas, L.

Re-evaluation of some factors affecting the stability of rat thyroglobulin.

Lamas, L, Santisteban, P .

C/ Arturo Duperier 4 | 28029 Madrid (España) | Teléfono +(34) 91 585 4400 | Código DIR3: E02764003