Departamentos

Funding

We gratefully acknowledge the national and international funders, whose continued support is essential to the progress and sustainability of our scientific work. We also sincerely thank the patients who have contributed to our research, as their participation is vital.

Research projects in the last 10 years:

 

2026-2029           European Union under Horizon Europe. EP PerMed JTC2025. EPPERMED2025-088–pRCC-TREAT. Proyecto: «Molecular-based stratification of metastatic papillary renal cell carcinoma to personalize treatment strategies» Coordinator: Rodríguez-Antona, IIBM

 

2025-2028           Spanish Ministry of Science and Innovation PID2024-158237OB-I00. Project: “Uncovering therapeutic opportunities for metastatic renal cell carcinomas: genomic definition and molecular mechanisms. THERo-RenCa”

 

2018-2026           Fundación Pública Andaluza para la Gestión de la Investigación en Salud de Sevilla (FISEVI). Project: “Caracterización molecular de subpoblaciones de tumores de células germinales avanzados resistentes a cisplatino: diseño de una firma genética”

 

2022-2025           Spanish Ministry of Science and Innovation PID2021-128312OB-I00. Project: “Molecular alterations of metastatic renal cell carcinoma of clinical significance for antitumor drug response. kidneyALT”

 

2022-2023           Fundación HNA Premio investigación científica/Fundación para la Investigación Biomédica del Hospital 12 de Octubre. Project: “Pharmacogenomic study of the toxicity of trastuzumab-deruxtecan in breast cancer patients”.

 

2020-2022           Pfizer. Project: “Non-clear cell renal cell carcinoma genomics for the discovery of Axitinib predictive markers

 

2020-2021           Asociación Española Contra el Cáncer (AECC) Ideas Semilla 2020. Project: “Bypassing Nonsense Mediated mRNA Decay to enhance immunotherapy response in cancer”

 

2019-2021          Spanish Ministry of Economy and Competitiveness RTI2018-095039-B-I00. Project: “Improving the clinical management of advanced renal cell carcinoma through genomic technologies (RCC-MARKER)”

 

2019-2020           Grupo Español de Tumores Neuroendocrinos y Endocrinos (GETNE). Biomarkers study in:. Project: “Estudio Fase II para evaluar la actividad y seguridad de TH302 en combinación con sunitinib para pacientes con tumores neuroendocrinos pancreáticos (pNET) bien o moderadamente diferenciados metastásicos no tratados previamente”.

 

2018-2019           Pfizer. Project: “Whole Exome Sequencing in extreme sunitinib responder patients to identify predictive markers: integration of germline and tumor variation”.

 

2017-2018           Spanish Oncology GenitoUrinary Group (SOGUG). Project: “Estudio observacional prospectivo y multicéntrico, para identificar biomarcadores con valor pronóstico y predictivo de respuesta a fármacos antiangiogénicos aprobados en el tratamiento en primera línea del carcinoma de células renales metastásico/localmente “

 

2016-2018          Spanish Ministry of Economy and Competitiveness SAF2015-64850-R. Project: “Identification of genetic markers and physiopathologic factors predictive of the peripheral neuropathy of paclitaxel and of other oncologic drugs: massive sequencing of candidate genes”

 

2016-2018           Spanish Oncology GenitoUrinary Group (SOGUG). Project: “Estudio multicéntrico retrospectivo para explorar la eficacia de diferentes secuencias de tratamiento e identificar biomarcadores de respuesta a axitinib”

 

2015-2016          Spanish Ministry of Economy and Competitiveness SAF2015-70820-ERC. Project: “Predicting antiangiogenic drug response in cancer: markers and mechanisms”

 

2014-2016          Pfizer. Project: “microRNAs as predictors of response to sunitinib in patients with clear cell renal cell carcinoma”

 

2012-2015           Leiden University Medical Center. Project: “Cross-validation of the genetic polymorphisms associated with sunitinib

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