News

The IIBM says a sad farewell to our dear colleague, Sebastián Cerdán

Dr. Sebastián Cerdán, CSIC Research Professor, colleague of all at the Instituto de Investigaciones Biomédicas Alberto Sols, IIBM (CSIC-UAM) , a colleague of all of us and friend of many of us, passed away last May 14th. His unexpected death has caused deep sorrow in all of us who have worked with him over the years, for whom he has been much more than a master. On a professional level Dr. Cerdán has been a brilliant and tireless scientist internationally recognized as a reference in the field of magnetic resonance, so it has been a great loss. He achieved numerous accomplishments that are easily found in the literature and attained positions of great prestige, most notably the Presidency of the European Society of Magnetic Resonance (ESMRMB), being a member of the management board of the International Society of Magnetic Resonance (ISMRM) and...

The Neuropathology of Hearing and Myelinopathies (IIBM-CSIC-UAM) organizes the online conference "Hearing health for a better quality of life" to celebrate the World Hearing Day 2022.

The online conference "Hearing health for a better quality of life" was held with great success on March 28th. It was the first presentation of the World Hearing Report prepared by the World Health Organization (WHO), which presents alarming data on the prevalence of hearing problems and the estimated increase in the coming decades, especially those forms associated with aging and exposure to noise. This was followed by an interesting discussion on the importance of maintaining good hearing health, avoiding exposure to intense noise, taking care of diet and consulting medical specialists regularly, in order to prevent hearing loss and ensure a better quality of life. Associations of patients with hearing loss, experts in nutrition, as well as clinicians and CIBERER researchers took part in the discussion. To conclude the day, an educational video...

Dr. Isabel Varela from the IIBM (CSIC-UAM) participates in the popular science program "Entre probetas" of Radio 5 to talk about hearing

  Isabel Varela-Nieto , Head of the research group in Neuropathology of Hearing and Myelinopathies at the Instituto de Investigaciones Biomédicas Alberto Sols, IIBM (CSIC-UAM) has recently participated in the science outreach program " Entre probetas " of Radio 5 (Radio Nacional de España), due to the celebration of World Hearing Day. The CSIC Professor is an excellent science communicator, bringing to society her knowledge about the genetic and molecular basis of hearing and hearing degeneration. In the program "Entre probetas", presented and directed by José Antonio López Guerrero, another great science communicator, Dr. Varela Nieto highlighted the great impact that hearing loss plays on our quality of life and the importance of maintaining proper hearing health throughout our lives, since the organ of hearing does not regenerate...

New role discovered for NOD1 protein in iron-related diseases

  Researchers from the Instituto de Investigaciones Biomédicas Alberto Sols (IIBM), CSIC-UAM, have published a new study about the novel function of NOD1 protein in iron homeostasis and in the process of cell death due to excess of iron This important work represents the pavement of new avenues of research in the diagnosis and treatment of iron-related diseases, as well as the identification of new therapeutic targets to combat different immunometabolic pathologies. The NOD1 protein, which had been previously related to inflammatory and cardiovascular pathologies, also plays an important role in the balance of iron levels in the body (homeostasis) and in the mechanisms of cell death due to excess iron (ferroptosis), according to a study recently released in the journal Biomedicine & Pharmacotherapy . The work has...

Researchers of the IIBM, CSIC-UAM, celebrate with great success the course "Advances in research with experimental models: the future of the 3R"

The Neuropathology of Hearing and Myelinopathies research group of the Instituto de Investigaciones Biomédicas Alberto Sols (IIBM), CSIC-UAM, led by Dr. Isabel Varela has organized the course " Advances in Research with Experimental Models: the future of the 3Rs ", in collaboration with the Colegio de Veterinarios de Madrid (COLVEMA) and the Universidad Complutense de Madrid (UCM). The course lasted three days and was held in a hybrid format (face-to-face and online). The course was very well received, with more than 200 attendees, mainly biomedical professionals interested in learning about the latest techniques in research with experimental models and future alternatives to the use of animals. The course featured prominent speakers in this field of research, including several members of the Plataforma de Biobancos y Biomodelos del Instituto de...

New insights into the fibroinflammatory microenvironment of pancreatic cancer bring us closer to a new therapeutic strategy

Researchers from the Instituto de Investigaciones Biomédicas "Alberto Sols" (IIBm), a joint center of the CSIC and the UAM, have published a study in the prestigious journal GUT in which they unravel the important components of the fibroinflammatory microenvironment of pancreatic cancer, the fourth leading cause of cancer-related death worldwide. This study details the identification of lysyl oxidase-like protein 2 (LOXL2) as a key factor in the metastasis of this high-mortatility tumor. This may represent a new therapeutic approach to reduce the metastatic potential of pancreatic ductal adenocarcinoma tumor cells This work , published in the prestigous journal GUT , has been led by Drs. Bruno Sainz Anding and Amparo Cano and carried out by the Cancer Stem Cells and Fibroinflammatory Microenvironment Group of the Instituto de...

Possible new therapy against cerebral malaria

The teams of Ana Aranda and Susana Alemany from the Instituto de Investigaciones Biomédicas "Alberto Sols", a joint center of the Consejo Superior de Investigaciones Científicas (CSIC) and the Universidad Autónoma de Madrid (UAM) have demonstrated that hypothyroidism protects against cerebral malaria, reducing neurological symptoms and significantly increasing survival in mice infected by the Plasmodium parasite. The results, published in the journal Science Advances , open the door to a possible new therapeutic target against cerebral malaria in children, a disease that kills several hundred thousand children annually in endemic areas . A team of Spanish researchers led by Drs. Ana Aranda and Susana Alemany from the Instituto de Investigaciones Biomédicas "Alberto Sols" (IIBM) -a joint center of the Universidad Autónoma de Madrid ( UAM ) and...

The Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM) participates in the 4ºESO+Empresa 2022 Program of the Community of Madrid

  Three students from the Santamarca Secondary School will become familiar with the world of biomedical research in the laboratories of two IIBM researchers, Ángela Martínez Valverde and María Monsalve Pérez 4ºESO+Empresa is an educational program of the Autonomous Community of Madrid to bring the educational system closer to the professional world. It is aimed at all students in the 4th year of Secondary Education. Basically, this initiative consists of students volunteering to spend a few days at the facilities of a company or institution to observe and participate in the activities carried out in these environments. In this way, young people are better prepared to make decisions about their academic and professional future, motivating them and providing them with the necessary skills. CSIC Institutes, Centers and Units...

Dr. Guillermo de Cárcer's group participates in the presentation of "Madrid en Marcha contra el Cáncer"

  Guillermo de Cárcer Díez , director of the Department of Cancer Biology at the Instituto de Investigaciones Biomédicas 'Alberto Sols' CSIC-UAM (IIBM) participated on Thursday, March 17 in the presentation of the race " March against Cancer " organized by the Spanish Association Against Cancer (AECC), which will take place on March 27 in Madrid. At the event, Dr. Guillermo de Cárcer was accompanied by three members of his research group: Ana Monfort Vengut, Natalia Sanz Gómez and María González Álvarez (in the picture).   The event took place in the auditorium of the Madrid City Hall and was attended by numerous personalities, including the president of the AECC of Madrid, Laura Ruiz de Galarreta, the mayor of Madrid, José Luis Martínez Almeida, the councilor for sports, Sofía Miranda, as well as other politicians and...

T Lymphocyte and CAR-T Cell-Derived Extracellular Vesicles and Their Applications in Cancer Therapy

Víctor Calvo and Manuel Izquierdo, Researchers at the Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), have published an exhaustive review that addresses the generation of extracellular vesicles by T lymphocytes and CAR-T cells and their possible therapeutic uses against Cancer. Víctor Calvo and Manuel Izquierdo , researchers at the Instituto de Investigaciones Biomédicas Alberto Sols (IIBM) , CSIC Joint Center and the Universidad Autónoma de Madrid (UAM) have explained in detail the biological relevance of extracellular vesicles (EV) derived from T lymphocytes and from chimeric antigen receptor T cells (CAR-T). The authors explain that EVs are a highly diverse group of extracellular vesicles released by almost all cell types and involved in intercellular communication. This is due to the fact that they deliver proteins, lipids and other...