Publicaciones
Trabajos Publicados   Isabel Varela Nieto   

1.- Wesdorp, M, Murillo-Cuesta, S , Peters, T, Celaya, AM, Oonk, A, Schraders, M, Oostrik, J, Gomez-Rosas, E, Beynon, AJ, Hartel, BP, Okkersen, K, Koenen, HJPM, Weeda, J, Lelieveld, S, Voermans, NC, Joosten, I, Hoyng, CB, Lichtner, P, Kunst, HPM, Feenstra, I, de Bruijn, SE, , , Admiraal, RJC, Yntema, HG, van Wijk, E, Del Castillo, I, Serra, P, Varela-Nieto, I , Pennings, RJE, Kremer, H. (2018). MPZL2, Encoding the Epithelial Junctional Protein Myelin Protein Zero-like 2, Is Essential for Hearing in Man and Mouse. Am. J. Hum. Genet. 103(1): 74-88 (PMID: 29961571)
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2.- Espino Guarch, M, Font-Llitjós, M, Murillo-Cuesta, S , Errasti-Murugarren, E, Celaya, AM, Girotto, G, Vuckovic, D, Mezzavilla, M, Vilches, C, Bodoy, S, Sahún, I, González, L , Prat, E, Zorzano, A, Dierssen, M, Varela-Nieto, I , Gasparini, P, Palacín, M, Nunes, V. (2018). Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss. Elife. 7(PMID: 29355479) Abstract
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3.- García-Alcántara, F, Murillo-Cuesta, S , Pulido, S, Bermúdez-Muñoz, JM, Martínez-Vega, R , Milo, M , Varela-Nieto, I , Rivera, T. (2017). The expression of oxidative stress response genes is modulated by a combination of resveratrol and N-acetylcysteine to ameliorate ototoxicity in the rat cochlea. Hear. Res. 358: 10-21 (PMID: 29304389) Abstract
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4.- Rodríguez-de la Rosa, L , Lassaletta, L , Calvino, M, Murillo-Cuesta, S , Varela-Nieto, I . (2017). The Role of Insulin-Like Growth Factor 1 in the Progression of Age-Related Hearing Loss. Front Aging Neurosci. 9: 411 (PMID: 29311900) Abstract
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5.- Lassaletta, L , Polak, M, Huesers, J, Díaz-Gómez, M, Calvino, M, Varela-Nieto, I , Gavilán, J. (2017). Usefulness of Electrical Auditory Brainstem Responses to Assess the Functionality of the Cochlear Nerve Using an Intracochlear Test Electrode. Otol. Neurotol. 38(10): e413-e420 (PMID: 29076926) Abstract
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6.- Magariños, M , Pulido, S, Aburto, MR , de Iriarte Rodríguez, R, Varela-Nieto, I . (2017). Autophagy in the Vertebrate Inner Ear. Front Cell Dev Biol. 5: 56 (PMID: 28603711) Abstract
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7.- Partearroyo, T, Vallecillo, N, Pajares, MA , Varela-Moreiras, G, Varela-Nieto, I . (2017). Cochlear Homocysteine Metabolism at the Crossroad of Nutrition and Sensorineural Hearing Loss. Front Mol Neurosci. 10: 107 (PMID: 28487633) Abstract
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8.- Murillo-Cuesta, S , Vallecillo, N, Cediel, R , Celaya, AM, Lassaletta, L , Varela-Nieto, I , Contreras, J . (2017). A Comparative Study of Drug Delivery Methods Targeted to the Mouse Inner Ear: Bullostomy Versus Transtympanic Injection. J Vis Exp. (121)(PMID: 28362376) Abstract
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9.- Klionsky, DJ, Abdelmohsen, K, Abe, A, Abedin, MJ, Abeliovich, H, Acevedo Arozena, A, Adachi, H, Adams, CM, Adams, PD, Adeli, K, Adhihetty, PJ, Adler, SG, Agam, G, Agarwal, R, Aghi, MK, Agnello, M, Agostinis, P, Aguilar, PV, Aguirre-Ghiso, J, Airoldi, EM, Ait-Si-Ali, S, Akematsu, T, Akporiaye, ET, Al-Rubeai, M, Albaiceta, GM, Albanese, C, Albani, D, Albert, ML, Aldudo, J, Algül, H, Alirezaei, M, Alloza, I, Almasan, A, Almonte-Beceril, M, Alnemri, ES, Alonso, C, Altan-Bonnet, N, Altieri, DC, Alvarez, S, Alvarez-Erviti, L, Alves, S, Amadoro, G, Amano, A, Amantini, C, Ambrosio, S, Amelio, I, Amer, AO, Amessou, M, Amon, A, An, Z, Anania, FA, Andersen, SU, Andley, UP, Andreadi, CK, Andrieu-Abadie, N, Anel, A, Ann, DK, Anoopkumar-Dukie, S, Antonioli, M, Aoki, H, Apostolova, N, Aquila, S, Aquilano, K, Araki, K, Arama, E, Aranda, A, Araya, J, Arcaro, A, Arias, E, Arimoto, H, Ariosa, AR, Armstrong, JL, Arnould, T, Arsov, I, Asanuma, K, Askanas, V, Asselin, E, Atarashi, R, Atherton, SS, Atkin, JD, Attardi, LD, Auberger, P, Auburger, G, Aurelian, L, Autelli, R, Avagliano, L, Avantaggiati, ML, Avrahami, L, Awale, S, Azad, N, Bachetti, T, Backer, JM, Bae, DH, Bae, JS, Bae, ON, Bae, SH, Baehrecke, EH, Baek, SH, Baghdiguian, S, Bagniewska-Zadworna, A, Bai, H, Bai, J, Bai, XY, Bailly, Y, Balaji, KN, Balduini, W, Ballabio, A, Balzan, R, Banerjee, R, Bánhegyi, G, Bao, H, Barbeau, B, Barrachina, MD, Barreiro, E, Bartel, B, Bartolomé, A, Bassham, DC, Bassi, MT, Bast, RC, Basu, A, Batista, MT, Batoko, H, Battino, M, Bauckman, K, Baumgarner, BL, Bayer, KU, Beale, R, Beaulieu, JF, Beck, GR, Becker, C, Beckham, JD, Bédard, PA, Bednarski, PJ, Begley, TJ, Behl, C, Behrends, C, Behrens, GM, Behrns, KE, Bejarano, E, Belaid, A, Belleudi, F, Bénard, G, Berchem, G, Bergamaschi, D, Bergami, M, Berkhout, B, Berliocchi, L, Bernard, A, Bernard, M, Bernassola, F, Bertolotti, A, Bess, AS, Besteiro, S, Bettuzzi, S, Bhalla, S, Bhattacharyya, S, Bhutia, SK, Biagosch, C, Bianchi, MW, Biard-Piechaczyk, M, Billes, V, Bincoletto, C, Bingol, B, Bird, SW, Bitoun, M, Bjedov, I, Blackstone, C, Blanc, L, Blanco, GA, Blomhoff, HK, Boada-Romero, E, Böckler, S, Boes, M, Boesze-Battaglia, K, Boise, LH, Bolino, A, Boman, A, Bonaldo, P, Bordi, M, Bosch, J, Botana, LM, Botti, J, Bou, G, Bouché, M, Bouchecareilh, M, Boucher, MJ, Boulton, ME, Bouret, SG, Boya, P, Boyer-Guittaut, M, Bozhkov, PV, Brady, N, Braga, VM, Brancolini, C, Braus, GH, Bravo-San Pedro, JM, Brennan, LA, Bresnick, EH, Brest, P, Bridges, D, Bringer, MA, Brini, M, Brito, GC, Brodin, B, Brookes, PS, Brown, EJ, Brown, K, Broxmeyer, HE, Bruhat, A, Brum, PC, Brumell, JH, Brunetti-Pierri, N, Bryson-Richardson, RJ, Buch, S, Buchan, AM, Budak, H, Bulavin, DV, Bultman, SJ, Bultynck, G, Bumbasirevic, V, Burelle, Y, Burke, RE, Burmeister, M, Bütikofer, P, Caberlotto, L, Cadwell, K, Cahova, M, Cai, D, Cai, J, Cai, Q, Calatayud, S, Camougrand, N, Campanella, M, Campbell, GR, Campbell, M, Campello, S, Candau, R, Caniggia, I, Cantoni, L, Cao, L, Caplan, AB, Caraglia, M, Cardinali, C, Cardoso, SM, Carew, JS, Carleton, LA, Carlin, CR, Carloni, S, Carlsson, SR, Carmona-Gutierrez, D, Carneiro, LA, Carnevali, O, Carra, S, Carrier, A, Carroll, B, Casas, C, Casas, J, Cassinelli, G, Castets, P, Castro-Obregon, S, Cavallini, G, Ceccherini, I, Cecconi, F, Cederbaum, AI, Ceña, V, Cenci, S, Cerella, C, Cervia, D, Cetrullo, S, Chaachouay, H, Chae, HJ, Chagin, AS, Chai, CY, Chakrabarti, G, Chamilos, G, Chan, EY, Chan, MT, Chandra, D, Chandra, P, Chang, CP, Chang, RC, Chang, TY, Chatham, JC, Chatterjee, S, Chauhan, S, Che, Y, Cheetham, ME, Cheluvappa, R, Chen, CJ, Chen, G, Chen, GC, Chen, G, Chen, H, Chen, JW, Chen, JK, Chen, M, Chen, M, Chen, P, Chen, Q, Chen, Q, Chen, SD, Chen, S, Chen, SS, Chen, W, Chen, WJ, Chen, WQ, Chen, W, Chen, X, Chen, YH, Chen, YG, Chen, Y, Chen, Y, Chen, Y, Chen, YJ, Chen, YQ, Chen, Y, Chen, Z, Chen, Z, Cheng, A, Cheng, CH, Cheng, H, Cheong, H, Cherry, S, Chesney, J, Cheung, CH, Chevet, E, Chi, HC, Chi, SG, Chiacchiera, F, Chiang, HL, Chiarelli, R, Chiariello, M, Chieppa, M, Chin, LS, Chiong, M, Chiu, GN, Cho, DH, Cho, SG, Cho, WC, Cho, YY, Cho, YS, Choi, AM, Choi, EJ, Choi, EK, Choi, J, Choi, ME, Choi, SI, Chou, TF, Chouaib, S, Choubey, D, Choubey, V, Chow, KC, Chowdhury, K, Chu, CT, Chuang, TH, Chun, T, Chung, H, Chung, T, Chung, YL, Chwae, YJ, Cianfanelli, V, Ciarcia, R, Ciechomska, IA, Ciriolo, MR, Cirone, M, Claerhout, S, Clague, MJ, Clària, J, Clarke, PG, Clarke, R, Clementi, E, Cleyrat, C, Cnop, M, Coccia, EM, Cocco, T, Codogno, P, Coers, J, Cohen, EE, Colecchia, D, Coletto, L, Coll, NS, Colucci-Guyon, E, Comincini, S, Condello, M, Cook, KL, Coombs, GH, Cooper, CD, Cooper, JM, Coppens, I, Corasaniti, MT, Corazzari, M, Corbalan, R, Corcelle-Termeau, E, Cordero, MD, Corral-Ramos, C, Corti, O, Cossarizza, A, Costelli, P, Costes, S, Cotman, SL, Coto-Montes, A, Cottet, S, Couve, E, Covey, LR, Cowart, LA, Cox, JS, Coxon, FP, Coyne, CB, Cragg, MS, Craven, RJ, Crepaldi, T, Crespo, JL, Criollo, A, Crippa, V, Cruz, MT, Cuervo, AM, Cuezva, JM, Cui, T, Cutillas, PR, Czaja, MJ, Czyzyk-Krzeska, MF, Dagda, RK, Dahmen, U, Dai, C, Dai, W, Dai, Y, Dalby, KN, Dalla Valle, L, Dalmasso, G, D'Amelio, M, Damme, M, Darfeuille-Michaud, A, Dargemont, C, Darley-Usmar, VM, Dasarathy, S, Dasgupta, B, Dash, S, Dass, CR, Davey, HM, Davids, LM, Dávila, D, Davis, RJ, Dawson, TM, Dawson, VL, Daza, P, de Belleroche, J, de Figueiredo, P, de Figueiredo, RC, de la Fuente, J, De Martino, L, De Matteis, A, De Meyer, GR, De Milito, A, De Santi, M, de Souza, W, De Tata, V, De Zio, D, Debnath, J, Dechant, R, Decuypere, JP, Deegan, S, Dehay, B, Del Bello, B, Del Re, DP, Delage-Mourroux, R, Delbridge, LM, Deldicque, L, Delorme-Axford, E, Deng, Y, Dengjel, J, Denizot, M, Dent, P, Der, CJ, Deretic, V, Derrien, B, Deutsch, E, Devarenne, TP, Devenish, RJ, Di Bartolomeo, S, Di Daniele, N, Di Domenico, F, Di Nardo, A, Di Paola, S, Di Pietro, A, Di Renzo, L, DiAntonio, A, Díaz-Araya, G, Díaz-Laviada, I, Diaz-Meco, MT, Diaz-Nido, J, Dickey, CA, Dickson, RC, Diederich, M, Digard, P, Dikic, I, Dinesh-Kumar, SP, Ding, C, Ding, WX, Ding, Z, Dini, L, Distler, JH, Diwan, A, Djavaheri-Mergny, M, Dmytruk, K, Dobson, RC, Doetsch, V, Dokladny, K, Dokudovskaya, S, Donadelli, M, Dong, XC, Dong, X, Dong, Z, Donohue, TM, Doran, KS, D'Orazi, G, Dorn, GW, Dosenko, V, Dridi, S, Drucker, L, Du, J, Du, LL, Du, L, du Toit, A, Dua, P, Duan, L, Duann, P, Dubey, VK, Duchen, MR, Duchosal, MA, Duez, H, Dugail, I, Dumit, VI, Duncan, MC, Dunlop, EA, Dunn, WA, Dupont, N, Dupuis, L, Durán, RV, Durcan, TM, Duvezin-Caubet, S, Duvvuri, U, Eapen, V, Ebrahimi-Fakhari, D, Echard, A, Eckhart, L, Edelstein, CL, Edinger, AL, Eichinger, L, Eisenberg, T, Eisenberg-Lerner, A, Eissa, NT, El-Deiry, WS, El-Khoury, V, Elazar, Z, Eldar-Finkelman, H, Elliott, CJ, Emanuele, E, Emmenegger, U, Engedal, N, Engelbrecht, AM, Engelender, S, Enserink, JM, Erdmann, R, Erenpreisa, J, Eri, R, Eriksen, JL, Erman, A, Escalante, R , Eskelinen, EL, Espert, L, Esteban-Martínez, L, Evans, TJ, Fabri, M, Fabrias, G, Fabrizi, C, Facchiano, A, Færgeman, NJ, Faggioni, A, Fairlie, WD, Fan, C, Fan, D, Fan, J, Fang, S, Fanto, M, Fanzani, A, Farkas, T, Faure, M, Favier, FB, Fearnhead, H, Federici, M, Fei, E, Felizardo, TC, Feng, H, Feng, Y, Feng, Y, Ferguson, TA, Fernández, ÁF, Fernandez-Barrena, MG, Fernandez-Checa, JC, Fernández-López, A, Fernandez-Zapico, ME, Feron, O, Ferraro, E, Ferreira-Halder, CV, Fesus, L, Feuer, R, Fiesel, FC, Filippi-Chiela, EC, Filomeni, G, Fimia, GM, Fingert, JH, Finkbeiner, S, Finkel, T, Fiorito, F, Fisher, PB, Flajolet, M, Flamigni, F, Florey, O, Florio, S, Floto, RA, Folini, M, Follo, C, Fon, EA, Fornai, F, Fortunato, F, Fraldi, A, Franco, R, Francois, A, François, A, Frankel, LB, Fraser, ID, Frey, N, Freyssenet, DG, Frezza, C, Friedman, SL, Frigo, DE, Fu, D, Fuentes, JM, Fueyo, J, Fujitani, Y, Fujiwara, Y, Fujiya, M, Fukuda, M, Fulda, S, Fusco, C, Gabryel, B, Gaestel, M, Gailly, P, Gajewska, M, Galadari, S, Galili, G, Galindo, I, Galindo, MF, Galliciotti, G, Galluzzi, L, Galluzzi, L, Galy, V, Gammoh, N, Gandy, S, Ganesan, AK, Ganesan, S, Ganley, IG, Gannagé, M, Gao, FB, Gao, F, Gao, JX, García Nannig, L, García Véscovi, E, Garcia-Macía, M, Garcia-Ruiz, C, Garg, AD, Garg, PK, Gargini, R, Gassen, NC, Gatica, D, Gatti, E, Gavard, J, Gavathiotis, E, Ge, L, Ge, P, Ge, S, Gean, PW, Gelmetti, V, Genazzani, AA, Geng, J, Genschik, P, Gerner, L, Gestwicki, JE, Gewirtz, DA, Ghavami, S, Ghigo, E, Ghosh, D, Giammarioli, AM, Giampieri, F, Giampietri, C, Giatromanolaki, A, Gibbings, DJ, Gibellini, L, Gibson, SB, Ginet, V, Giordano, A, Giorgini, F, Giovannetti, E, Girardin, SE, Gispert, S, Giuliano, S, Gladson, CL, Glavic, A, Gleave, M, Godefroy, N, Gogal, RM, Gokulan, K, Goldman, GH, Goletti, D, Goligorsky, MS, Gomes, AV, Gomes, LC, Gomez, H, Gomez-Manzano, C, Gómez-Sánchez, R, Gonçalves, DA, Goncu, E, Gong, Q, Gongora, C, Gonzalez, CB, Gonzalez-Alegre, P, Gonzalez-Cabo, P, González-Polo, RA, Goping, IS, Gorbea, C, Gorbunov, NV, Goring, DR, Gorman, AM, Gorski, SM, Goruppi, S, Goto-Yamada, S, Gotor, C, Gottlieb, RA, Gozes, I, Gozuacik, D, Graba, Y, Graef, M, Granato, GE, Grant, GD, Grant, S, Gravina, GL, Green, DR, Greenhough, A, Greenwood, MT, Grimaldi, B, Gros, F, Grose, C, Groulx, JF, Gruber, F, Grumati, P, Grune, T, Guan, JL, Guan, KL, Guerra, B, Guillen, C, Gulshan, K, Gunst, J, Guo, C, Guo, L, Guo, M, Guo, W, Guo, XG, Gust, AA, Gustafsson, ÅB, Gutierrez, E, Gutierrez, MG, Gwak, HS, Haas, A, Haber, JE, Hadano, S, Hagedorn, M, Hahn, DR, Halayko, AJ, Hamacher-Brady, A, Hamada, K, Hamai, A, Hamann, A, Hamasaki, M, Hamer, I, Hamid, Q, Hammond, EM, Han, F, Han, W, Handa, JT, Hanover, JA, Hansen, M, Harada, M, Harhaji-Trajkovic, L, Harper, JW, Harrath, AH, Harris, AL, Harris, J, Hasler, U, Hasselblatt, P, Hasui, K, Hawley, RG, Hawley, TS, He, C, He, CY, He, F, He, G, He, RR, He, XH, He, YW, He, YY, Heath, JK, Hébert, MJ, Heinzen, RA, Helgason, GV, Hensel, M, Henske, EP, Her, C, Herman, PK, Hernández, A, Hernandez, C, Hernández-Tiedra, S, Hetz, C, Hiesinger, PR, Higaki, K, Hilfiker, S, Hill, BG, Hill, JA, Hill, WD, Hino, K, Hofius, D, Hofman, P, Höglinger, GU, Höhfeld, J, Holz, MK, Hong, Y, Hood, DA, Hoozemans, JJ, Hoppe, T, Hsu, C, Hsu, CY, Hsu, LC, Hu, D, Hu, G, Hu, HM, Hu, H, Hu, MC, Hu, YC, Hu, ZW, Hua, F, Hua, Y, Huang, C, Huang, HL, Huang, KH, Huang, KY, Huang, S, Huang, S, Huang, WP, Huang, YR, Huang, Y, Huang, Y, Huber, TB, Huebbe, P, Huh, WK, Hulmi, JJ, Hur, GM, Hurley, JH, Husak, Z, Hussain, SN, Hussain, S, Hwang, JJ, Hwang, S, Hwang, TI, Ichihara, A, Imai, Y, Imbriano, C, Inomata, M, Into, T, Iovane, V, Iovanna, JL, Iozzo, RV, Ip, NY, Irazoqui, JE, Iribarren, P, Isaka, Y, Isakovic, AJ, Ischiropoulos, H, Isenberg, JS, Ishaq, M, Ishida, H, Ishii, I, Ishmael, JE, Isidoro, C, Isobe, K, Isono, E, Issazadeh-Navikas, S, Itahana, K, Itakura, E, Ivanov, AI, Iyer, AK, Izquierdo, JM, Izumi, Y, Izzo, V, Jäättelä, M, Jaber, N, Jackson, DJ, Jackson, WT, Jacob, TG, Jacques, TS, Jagannath, C, Jain, A, Jana, NR, Jang, BK, Jani, A, Janji, B, Jannig, PR, Jansson, PJ, Jean, S, Jendrach, M, Jeon, JH, Jessen, N, Jeung, EB, Jia, K, Jia, L, Jiang, H, Jiang, H, Jiang, L, Jiang, T, Jiang, X, Jiang, X, Jiang, Y, Jiang, Y, Jiménez, A, Jin, C, Jin, H, Jin, L, Jin, M, Jin, S, Jinwal, UK, Jo, EK, Johansen, T, Johnson, DE, Johnson, GV, Johnson, JD, Jonasch, E, Jones, C, Joosten, LA, Jordan, J, Joseph, AM, Joseph, B, Joubert, AM, Ju, D, Ju, J, Juan, HF, Juenemann, K, Juhász, G, Jung, HS, Jung, JU, Jung, YK, Jungbluth, H, Justice, MJ, Jutten, B, Kaakoush, NO, Kaarniranta, K, Kaasik, A, Kabuta, T, Kaeffer, B, Kågedal, K, Kahana, A, Kajimura, S, Kakhlon, O, Kalia, M, Kalvakolanu, DV, Kamada, Y, Kambas, K, Kaminskyy, VO, Kampinga, HH, Kandouz, M, Kang, C, Kang, R, Kang, TC, Kanki, T, Kanneganti, TD, Kanno, H, Kanthasamy, AG, Kantorow, M, Kaparakis-Liaskos, M, Kapuy, O, Karantza, V, Karim, MR, Karmakar, P, Kaser, A, Kaushik, S, Kawula, T, Kaynar, AM, Ke, PY, Ke, ZJ, Kehrl, JH, Keller, KE, Kemper, JK, Kenworthy, AK, Kepp, O, Kern, A, Kesari, S, Kessel, D, Ketteler, R, Kettelhut, Ido C, Khambu, B, Khan, MM, Khandelwal, VK, Khare, S, Kiang, JG, Kiger, AA, Kihara, A, Kim, AL, Kim, CH, Kim, DR, Kim, DH, Kim, EK, Kim, HY, Kim, HR, Kim, JS, Kim, JH, Kim, JC, Kim, JH, Kim, KW, Kim, MD, Kim, MM, Kim, PK, Kim, SW, Kim, SY, Kim, YS, Kim, Y, Kimchi, A, Kimmelman, AC, Kimura, T, King, JS, Kirkegaard, K, Kirkin, V, Kirshenbaum, LA, Kishi, S, Kitajima, Y, Kitamoto, K, Kitaoka, Y, Kitazato, K, Kley, RA, Klimecki, WT, Klinkenberg, M, Klucken, J, Knævelsrud, H, Knecht, E, Knuppertz, L, Ko, JL, Kobayashi, S, Koch, JC, Koechlin-Ramonatxo, C, Koenig, U, Koh, YH, Köhler, K, Kohlwein, SD, Koike, M, Komatsu, M, Kominami, E, Kong, D, Kong, HJ, Konstantakou, EG, Kopp, BT, Korcsmaros, T, Korhonen, L, Korolchuk, VI, Koshkina, NV, Kou, Y, Koukourakis, MI, Koumenis, C, Kovács, AL, Kovács, T, Kovacs, WJ, Koya, D, Kraft, C, Krainc, D, Kramer, H, 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13.- Fuentes-Santamaría, V, Alvarado, JC, Rodríguez-de la Rosa, L , Murillo-Cuesta, S , Contreras, J , Juiz, JM, Varela-Nieto, I . (2016). Erratum to: IGF-1 deficiency causes atrophic changes associated with upregulation of VGluT1 and downregulation of MEF2 transcription factors in the mouse cochlear nuclei. Brain Struct Funct. 221(2): 1205 (PMID: 25416135)
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14.- Fuentes-Santamaría, V, Alvarado, JC, Rodríguez-de la Rosa, L , Murillo-Cuesta, S , Contreras, J , Juiz, JM, Varela-Nieto, I . (2016). IGF-1 deficiency causes atrophic changes associated with upregulation of VGluT1 and downregulation of MEF2 transcription factors in the mouse cochlear nuclei. Brain Struct Funct. 221(2): 709-734 (PMID: 25378055) Abstract
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15.- Buniello, A, Ingham, NJ, Lewis, MA, Huma, AC, Martinez-Vega, R, Varela-Nieto, I , Vizcay-Barrena, G, Fleck, RA, Houston, O, Bardhan, T, Johnson, SL, White, JK, Yuan, H, Marcotti, W, Steel, KP. (2016). Wbp2 is required for normal glutamatergic synapses in the cochlea and is crucial for hearing. EMBO Mol Med. 8(3): 191-207 (PMID: 26881968) Abstract
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16.- Martínez-Vega, R , Partearroyo, T, Vallecillo, N, Varela-Moreiras, G, Pajares, MA , Varela-Nieto, I . (2015). Long-term omega-3 fatty acid supplementation prevents expression changes in cochlear homocysteine metabolism and ameliorates progressive hearing loss in C57BL/6J mice. J. Nutr. Biochem. 26(12): 1424-1433 (PMID: 26321228) Abstract
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17.- de Iriarte Rodríguez, R, Pulido, S, Rodríguez-de la Rosa, L , Magariños, M , Varela-Nieto, I . (2015). Age-regulated function of autophagy in the mouse inner ear. Hear. Res. 330(Pt A): 39-50 (PMID: 26235979) Abstract
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18.- García-Díaz, B, Riquelme, R , Varela-Nieto, I , Jiménez, AJ, de Diego, I, Gómez-Conde, AI, Matas-Rico, E, Aguirre, JÁ, Chun, J, Pedraza, C, Santín, LJ, Fernández, O, Rodríguez de Fonseca, F, Estivill-Torrús, G. (2015). Loss of lysophosphatidic acid receptor LPA1 alters oligodendrocyte differentiation and myelination in the mouse cerebral cortex. Brain Struct Funct. 220(6): 3701-3720 (PMID: 25226845) Abstract
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19.- Apostolo, J, Holland, C, O'Connell, MD, Feeney, J, Tabares-Seisdedos, R, Tadros, G, Campos, E, Santos, N, Robertson, DA, Marcucci, M, Varela-Nieto, I , Crespo-Facorro, B, Vieta, E, Navarro-Pardo, E, Selva-Vera, G, Balanzá-Martínez, V, Cano, A. (2015). Mild cognitive decline. A position statement of the Cognitive Decline Group of the European Innovation Partnership for Active and Healthy Ageing (EIPAHA). Maturitas. (PMID: 26520249) Abstract
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20.- Bouillon, R, Slordahl, S, Nogueria, MM, Steinhausen, K, Varela-Nieto, I , Pacini, G, Röllinghoff, M, Syka, J. (2015). Public investment in biomedical research in Europe. Lancet. 386(10001): 1335 (PMID: 26460768)
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21.- de Iriarte Rodríguez, R, Magariños, M , Pfeiffer, V, Rapp, UR, Varela-Nieto, I . (2015). C-Raf deficiency leads to hearing loss and increased noise susceptibility. Cell. Mol. Life Sci. 72(20): 3983-3998 (PMID: 25975225) Abstract
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22.- Rodríguez-de la Rosa, L , Sánchez-Calderón, H , Contreras, J , Murillo-Cuesta, S , Falagan, S, Avendaño, C, Dopazo, J, Varela-Nieto, I , Milo, M . (2015). Comparative gene expression study of the vestibular organ of the Igf1 deficient mouse using whole-transcript arrays. Hear. Res. (PMID: 26341476) Abstract
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23.- Magariños, M , Milo, M , Varela-Nieto, I . (2015). Editorial: Aging, neurogenesis and neuroinflammation in hearing loss and protection. Front Aging Neurosci. 7: 138 (PMID: 26236234)
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24.- López, IP, Rodriguez-de la Rosa, L , Pais, RS, Piñeiro-Hermida, S, Torrens, R, Contreras, J , Varela-Nieto, I , Pichel, JG. (2015). Differential organ phenotypes after postnatal Igf1r gene conditional deletion induced by tamoxifen in UBC-CreERT2; Igf1r (fl/fl) double transgenic mice. Transgenic Res. 24(2): 279-294 (PMID: 25238791) Abstract
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25.- Murillo-Cuesta, S , Rodríguez-de la Rosa, L , Contreras, J , Celaya, AM, Camarero, G , Rivera, T, Varela-Nieto, I . (2015). Transforming growth factor β1 inhibition protects from noise-induced hearing loss. Front Aging Neurosci. 7: 32 (PMID: 25852546) Abstract
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26.- Sanz, L, Murillo-Cuesta, S , Cobo, P, Cediel-Algovia, R, Contreras, J , Rivera, T, Varela-Nieto, I , Avendaño, C. (2015). Swept-sine noise-induced damage as a hearing loss model for preclinical assays. Front Aging Neurosci. 7: 7 (PMID: 25762930) Abstract
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27.- Martínez-Vega, R , Garrido, F , Partearroyo, T, Cediel, R , Zeisel, SH, Martínez-Álvarez, C, Varela-Moreiras, G, Varela-Nieto, I , Pajares, MA . (2015). Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism. FASEB J. 29(2): 418-432 (PMID: 25384423) Abstract
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28.- Malgrange, B, Varela-Nieto, I , de Medina, P, Paillasse, MR. (2015). Targeting cholesterol homeostasis to fight hearing loss: a new perspective. Front Aging Neurosci. 7: 3 (PMID: 25688206) Abstract
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29.- Rodríguez-de la Rosa, L , López-Herradón, A, Portal-Núñez, S, Murillo-Cuesta, S , Lozano, D, Cediel, R , Varela-Nieto, I , Esbrit, P. (2014). Treatment with N- and C-terminal peptides of parathyroid hormone-related protein partly compensate the skeletal abnormalities in IGF-I deficient mice. PLoS ONE. 9(2): e87536 (PMID: 24503961) Abstract
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30.- Muñoz-Espín, D, Cañamero, M, Maraver, A, Gómez-López, G, Contreras, J , Murillo-Cuesta, S , Rodríguez-Baeza, A, Varela-Nieto, I , Ruberte, J, Collado, M, Serrano, M. (2013). Programmed cell senescence during mammalian embryonic development. Cell. 155(5): 1104-1118 (PMID: 24238962) Abstract
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31.- Varela-Nieto, I , Murillo-Cuesta, S , Rodríguez-de la Rosa, L , Lassatetta, L, Contreras, J . (2013). IGF-I deficiency and hearing loss: molecular clues and clinical implications. Pediatr Endocrinol Rev. 10(4): 460-472 (PMID: 23957197) Abstract
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32.- Magariños, M , Contreras, J , Aburto, MR , Varela-Nieto, I . (2012). Early development of the vertebrate inner ear. Anat Rec (Hoboken). 295(11): 1775-1790 (PMID: 23044927) Abstract
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33.- Aburto, MR , Sánchez-Calderón, H , Hurlé, JM, Varela-Nieto, I , Magariños, M . (2012). Early otic development depends on autophagy for apoptotic cell clearance and neural differentiation. Cell Death Dis. 3: e394 (PMID: 23034329) Abstract
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34.- Aburto, MR , Hurlé, JM, Varela-Nieto, I , Magariños, M . (2012). Autophagy during vertebrate development. Cells. 1(3): 428-448 (PMID: 24710484) Abstract
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35.- Rivera, T, Sanz, L, Camarero, G , Varela-Nieto, I . (2012). Drug delivery to the inner ear: strategies and their therapeutic implications for sensorineural hearing loss. Curr Drug Deliv. 9(3): 231-242 (PMID: 22283653) Abstract
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36.- Rodriguez-de la Rosa, L , Fernandez-Sanchez, L, Germain, F, Murillo-Cuesta, S , Varela-Nieto, I , de la Villa, P, Cuenca, N. (2012). Age-related functional and structural retinal modifications in the Igf1-/- null mouse. Neurobiol. Dis. 46(2): 476-485 (PMID: 22402333) Abstract
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37.- Murillo-Cuesta, S , Camarero, G , González-Rodríguez, A , De La Rosa, LR , Burks, DJ, Avendaño, C, Valverde, AM , Varela-Nieto, I . (2012). Insulin receptor substrate 2 (IRS2)-deficient mice show sensorineural hearing loss that is delayed by concomitant protein tyrosine phosphatase 1B (PTP1B) loss of function. Mol. Med. 18: 260-269 (PMID: 22160220) Abstract
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38.- Aburto, MR , Magariños, M , Leon, Y , Varela-Nieto, I , Sanchez-Calderon, H . (2012). AKT signaling mediates IGF-I survival actions on otic neural progenitors. PLoS ONE. 7(1): e30790 (PMID: 22292041) Abstract
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39.- Murillo-Cuesta, S , Rodríguez-de la Rosa, L , Cediel, R , Lassaletta, L , Varela-Nieto, I . (2011). The role of insulin-like growth factor-I in the physiopathology of hearing. Front Mol Neurosci. 4: 11 (PMID: 21845174) Abstract
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40.- Magariños, M , Aburto, MR , Sánchez-Calderón, H , Muñoz-Agudo, C , Rapp, UR, Varela-Nieto, I . (2010). RAF kinase activity regulates neuroepithelial cell proliferation and neuronal progenitor cell differentiation during early inner ear development. PLoS ONE. 5(12): e14435 (PMID: 21203386) Abstract
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41.- Riquelme, R , Cediel, R , Contreras, J , la Rosa Lourdes, RD , Murillo-Cuesta, S , Hernandez-Sanchez, C, Zubeldia, JM , Cerdan, S , Varela-Nieto, I . (2010). A comparative study of age-related hearing loss in wild type and insulin-like growth factor I deficient mice. Front Neuroanat. 4: 27 (PMID: 20661454) Abstract
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42.- Hovatta, O, Stojkovic, M, Nogueira, M, Varela-Nieto, I . (2010). European scientific, ethical, and legal issues on human stem cell research and regenerative medicine. Stem Cells. 28(6): 1005-1007 (PMID: 20533567)
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43.- Murillo-Cuesta, S , Contreras, J , Cediel, R , Varela-Nieto, I . (2010). Comparison of different aminoglycoside antibiotic treatments to refine ototoxicity studies in adult mice. Lab. Anim. 44(2): 124-131 (PMID: 19858169) Abstract
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44.- Murillo-Cuesta, S , Contreras, J , Zurita, E, Cediel, R , Cantero, M, Varela-Nieto, I , Montoliu, L. (2010). Melanin precursors prevent premature age-related and noise-induced hearing loss in albino mice. Pigment Cell Melanoma Res. 23(1): 72-83 (PMID: 19843244) Abstract
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45.- Sanchez-Calderon, H , Rodriguez-de la Rosa, L , Milo, M , Pichel, JG, Holley, M, Varela-Nieto, I . (2010). RNA microarray analysis in prenatal mouse cochlea reveals novel IGF-I target genes: implication of MEF2 and FOXM1 transcription factors. PLoS ONE. 5(1): e8699 (PMID: 20111592) Abstract
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46.- Murillo-Cuesta, S , García-Alcántara, F, Vacas, E , Sistiaga, JA, Camarero, G , Varela-Nieto, I , Rivera, T. (2009). Direct drug application to the round window: a comparative study of ototoxicity in rats. Otolaryngol Head Neck Surg. 141(5): 584-590 (PMID: 19861195) Abstract
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47.- Santin, LJ, Bilbao, A, Pedraza, C, Matas-Rico, E, López-Barroso, D, Castilla-Ortega, E, Sánchez-López, J, Riquelme, R , Varela-Nieto, I , de la Villa, P, Suardíaz, M, Chun, J, De Fonseca, FR, Estivill-Torrús, G. (2009). Behavioral phenotype of maLPA1-null mice: increased anxiety-like behavior and spatial memory deficits. Genes Brain Behav. 8(8): 772-784 (PMID: 19689455) Abstract
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48.- Fernández-Medarde, A, Barhoum, R, Riquelme, R , Porteros, A, Núñez, A, de Luis, A, de Las Rivas, J, de la Villa, P, Varela-Nieto, I , Santos, E. (2009). RasGRF1 disruption causes retinal photoreception defects and associated transcriptomic alterations. J. Neurochem. 110(2): 641-652 (PMID: 19457086) Abstract
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49.- Bell, D, Streit, A, Gorospe, I , Varela-Nieto, I , Alsina, B, Giraldez, F. (2008). Spatial and temporal segregation of auditory and vestibular neurons in the otic placode. Dev. Biol. 322(1): 109-120 (PMID: 18674529) Abstract
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50.- Rodríguez-de la Rosa, L , Contreras-Rodríguez, J , Cediel-Algovia, R , León, Y , Sánchez-Calderón, H , Murillo-Cuesta, S , Riquelme-Galiana, R , de Diego-Sastre, JI , Prim-Espada, MP , Varela-Nieto, I , , . (2008). [Neurotrophic action of insulin-like growth factor-I in the inner ear]. Rev Neurol. 45(4): 245-250 (PMID: 17668408) Abstract
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51.- Sanchez-Calderon, H , Milo, M , Leon, Y , Varela-Nieto, I . (2007). A network of growth and transcription factors controls neuronal differentation and survival in the developing ear. Int. J. Dev. Biol. 51(6-7): 557-570 (PMID: 17891717) Abstract
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52.- Varela-Nieto, I , Hartl, M, Gorospe, I , León, Y . (2007). Anti-apoptotic actions of insulin-like growth factors: lessons from development and implications in neoplastic cell transformation. Curr. Pharm. Des. 13(7): 687-703 (PMID: 17346184) Abstract
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53.- Conejero, L, Higaki, Y, Baeza, ML, Fernández, M , Varela-Nieto, I , Zubeldia, JM. (2007). Pollen-induced airway inflammation, hyper-responsiveness and apoptosis in a murine model of allergy. Clin. Exp. Allergy. 37(3): 331-338 (PMID: 17359383) Abstract
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54.- Cediel, R , Riquelme, R , Contreras, J , Díaz, A, Varela-Nieto, I . (2006). Sensorineural hearing loss in insulin-like growth factor I-null mice: a new model of human deafness. Eur. J. Neurosci. 23(2): 587-590 (PMID: 16420467) Abstract
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55.- Diaz-Casares, A, Leon, Y , de la Rosa, EJ, Varela-Nieto, I . (2005). Regulation of vertebrate sensory organ development: a scenario for growth hormone and insulin-like growth factors action. Adv. Exp. Med. Biol. 567: 221-242 (PMID: 16370141)
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56.- Jones, DR, Pañeda, C , Villar, AV, Alonso, A, Goñi, FM, Bütikofer, P, Brodbeck, U, Shepherd, PR, Varela-Nieto, I . (2005). Phosphorylation of glycosyl-phosphatidylinositol by phosphatidylinositol 3-kinase changes its properties as a substrate for phospholipases. FEBS Lett. 579(1): 59-65 (PMID: 15620691) Abstract
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57.- Varela-Nieto, I , Morales-Garcia, JA , Vigil, P, Diaz-Casares, A, Gorospe, I , Sánchez-Galiano, S, Cañon, S , Camarero, G , Contreras, J , Cediel, R , Leon, Y . (2004). Trophic effects of insulin-like growth factor-I (IGF-I) in the inner ear. Hear. Res. 196(1-2): 19-25 (PMID: 15464297) Abstract
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58.- Marí, M, Colell, A, Morales, A, Pañeda, C , Varela-Nieto, I , García-Ruiz, C, Fernández-Checa, JC. (2004). Acidic sphingomyelinase downregulates the liver-specific methionine adenosyltransferase 1A, contributing to tumor necrosis factor-induced lethal hepatitis. J. Clin. Invest. 113(6): 895-904 (PMID: 15067322) Abstract
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59.- Alsina, B, Giraldez, F, Varela-Nieto, I . (2003). Growth factors and early development of otic neurons: interactions between intrinsic and extrinsic signals. Curr. Top. Dev. Biol. 57: 177-206 (PMID: 14674481)
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60.- Camarero, G , Leon, Y, Gorospe, I , De Pablo, F, Alsina, B, Giraldez, F, Varela-Nieto, I . (2003). Insulin-like growth factor 1 is required for survival of transit-amplifying neuroblasts and differentiation of otic neurons. Dev. Biol. 262(2): 242-253 (PMID: 14550788) Abstract
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61.- Varela-Nieto, I , de la Rosa, EJ, Valenciano, AI, León, Y . (2003). Cell death in the nervous system: lessons from insulin and insulin-like growth factors. Mol. Neurobiol. 28(1): 23-50 (PMID: 14514984) Abstract
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62.- Frago, LM , Cañón, S , de la Rosa, EJ, León, Y , Varela-Nieto, I . (2003). Programmed cell death in the developing inner ear is balanced by nerve growth factor and insulin-like growth factor I. J. Cell. Sci. 116(Pt 3): 475-486 (PMID: 12508109) Abstract
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63.- Balboa, MA, Varela-Nieto, I , Killermann Lucas, K, Dennis, EA. (2002). Expression and function of phospholipase A(2) in brain. FEBS Lett. 531(1): 12-17 (PMID: 12401195) Abstract
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64.- Camarero, G , Villar, MA, Contreras, J , Fernández-Moreno, C, Pichel, JG, Avendaño, C, Varela-Nieto, I . (2002). Cochlear abnormalities in insulin-like growth factor-1 mouse mutants. Hear. Res. 170(1-2): 2-11 (PMID: 12208536) Abstract
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65.- Pañeda, C , Gorospe, I , Herrera, B, Nakamura, T, Fabregat, I, Varela-Nieto, I . (2002). Liver cell proliferation requires methionine adenosyltransferase 2A mRNA up-regulation. Hepatology. 35(6): 1381-1391 (PMID: 12029623) Abstract
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66.- Colombaioni, L, Frago, LM , Varela-Nieto, I , Pesi, R, Garcia-Gil, M. (2002). Serum deprivation increases ceramide levels and induces apoptosis in undifferentiated HN9.10e cells. Neurochem. Int. 40(4): 327-336 (PMID: 11792463) Abstract
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67.- Camarero, G , Avendano, C, Fernandez-Moreno, C, Villar, A, Contreras, J , de Pablo, F, Pichel, JG, Varela-Nieto, I . (2001). Delayed inner ear maturation and neuronal loss in postnatal Igf-1-deficient mice. J. Neurosci. 21(19): 7630-7641 (PMID: 11567053) Abstract
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68.- Pañeda, C , Villar, AV, Alonso, A, Goñi, FM, Varela, F, Brodbeck, U, León, Y , Varela-Nieto, I , Jones, DR. (2001). Purification and characterization of insulin-mimetic inositol phosphoglycan-like molecules from grass pea (Lathyrus sativus) seeds. Mol. Med. 7(7): 454-460 (PMID: 11683370) Abstract
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69.- Frago, LM , Pañeda, C , Fabregat, I, Varela-Nieto, I . (2001). Short-chain ceramide regulates hepatic methionine adenosyltransferase expression. J. Hepatol. 34(2): 192-201 (PMID: 11281546) Abstract
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70.- Pimentel, B, Sanz, C , Varela-Nieto, I , Rapp, UR, De Pablo, F, de La Rosa, EJ. (2000). c-Raf regulates cell survival and retinal ganglion cell morphogenesis during neurogenesis. J. Neurosci. 20(9): 3254-3262 (PMID: 10777790) Abstract
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71.- Frago, LM , Camerero, G, Cañón, S, Pañeda, C , Sanz, C , Leon, Y, Giraldez, F, Varela-Nieto, I . (2000). Role of diffusible and transcription factors in inner ear development: implications in regeneration. Histol. Histopathol. 15(2): 657-666 (PMID: 10809387) Abstract
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72.- Sanz, C , León, Y , Cañón, S, Alvarez, L , Giraldez, F, Varela-Nieto, I . (1999). Pattern of expression of the jun family of transcription factors during the early development of the inner ear: implications in apoptosis. J. Cell. Sci. 112 ( Pt 22): 3967-3974 (PMID: 10547357) Abstract
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73.- Villar, AV, Alonso, A, Pañeda, C , Varela-Nieto, I , Brodbeck, U, Goñi, FM. (1999). Towards the in vitro reconstitution of caveolae. Asymmetric incorporation of glycosylphosphatidylinositol (GPI) and gangliosides into liposomal membranes. FEBS Lett. 457(1): 71-74 (PMID: 10486566) Abstract
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74.- Jones, DR, Varela-Nieto, I . (1999). Diabetes and the role of inositol-containing lipids in insulin signaling. Mol. Med. 5(8): 505-514 (PMID: 10501653) Abstract
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75.- Varela-Nieto, I , Silos-Santiago, I. (1999). Introduction to structural and functional studies on nerve growth factor. Microsc. Res. Tech. 45(4-5): 206 (PMID: 10383111)
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76.- León, Y , Sanz, C , Frago, LM , Camarero, G , Cañón, S, Varela-Nieto, I , Giráldez, F. (1999). Involvement of insulin-like growth factor-I in inner ear organogenesis and regeneration. Horm. Metab. Res. 31(2-3): 126-132 (PMID: 10226792) Abstract
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77.- Sanz, C , León, Y , Troppmair, J, Rapp, UR, Varela-Nieto, I . (1999). Strict regulation of c-Raf kinase levels is required for early organogenesis of the vertebrate inner ear. Oncogene. 18(2): 429-437 (PMID: 9927199) Abstract
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78.- Petitfrere, E, Sartelet, H, Vivien, D, Varela-Nieto, I , Elbtaouri, H, Martiny, L, Haye, B. (1998). Glycosyl phosphatidylinositol (GPI)/inositolphosphate glycan (IPG): an intracellular signalling system involved in the control of thyroid cell proliferation. Biochimie. 80(12): 1063-1067 (PMID: 9924986) Abstract
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79.- León, Y , Sanz, C , Giráldez, F, Varela-Nieto, I . (1998). Induction of cell growth by insulin and insulin-like growth factor-I is associated with Jun expression in the otic vesicle. J. Comp. Neurol. 398(3): 323-332 (PMID: 9714146) Abstract
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80.- Villar, AV, Goñi, FM, Alonso, A, Jones, DR, León, Y , Varela-Nieto, I . (1998). Phospholipase cleavage of glycosylphosphatidylinositol reconstituted in liposomal membranes. FEBS Lett. 432(3): 150-154 (PMID: 9720914) Abstract
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81.- Frago, LM , Giménez, A, Rodriguez, EN , Varela-Nieto, I . (1998). Pattern of methionine adenosyltransferase isoenzyme expression during rat liver regeneration after partial hepatectomy. FEBS Lett. 426(3): 305-308 (PMID: 9600256) Abstract
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82.- Frago, LM , León, Y , de la Rosa, EJ, Gómez-Muñoz, A, Varela-Nieto, I . (1998). Nerve growth factor and ceramides modulate cell death in the early developing inner ear. J. Cell. Sci. 111 ( Pt 5): 549-556 (PMID: 9454729) Abstract
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83.- Jones, DR, Varela-Nieto, I . (1998). The role of glycosyl-phosphatidylinositol in signal transduction. Int. J. Biochem. Cell Biol. 30(3): 313-326 (PMID: 9611774) Abstract
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84.- Caro, HN, Kunjara, S, Rademacher, TW, León, Y , Jones, DR, Avila, MA, Varela-Nieto, I . (1997). Isolation and partial characterisation of insulin-mimetic inositol phosphoglycans from human liver. Biochem. Mol. Med. 61(2): 214-228 (PMID: 9259987) Abstract
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85.- Gomez-Muñoz, A, Frago, LM , Alvarez, L , Varela-Nieto, I . (1997). Stimulation of DNA synthesis by natural ceramide 1-phosphate. Biochem. J. 325 ( Pt 2): 435-440 (PMID: 9230125) Abstract
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86.- Jones, DR, Avila, MA, Sanz, C , Varela-Nieto, I . (1997). Glycosyl-phosphatidylinositol-phospholipase type D: a possible candidate for the generation of second messengers. Biochem. Biophys. Res. Commun. 233(2): 432-437 (PMID: 9144552) Abstract
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87.- Sanchez-Bueno, A, Greenwood, MR, Varela-Nieto, I , Marrero, I, Gil, B, Mato, JM , Cobbold, PH. (1997). Inositol-phosphoglycan inhibits calcium oscillations in hepatocytes by reducing calcium entry. Cell Calcium. 21(2): 125-133 (PMID: 9132295) Abstract
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88.- Leon, Y, Varela-Nieto, I , Breen, KC. (1997). Neural cell adhesion molecule expression in the developing chick otic vesicle. Biochem. Soc. Trans. 25(1): 10S (PMID: 9056908)
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89.- Varela-Nieto, I , León, Y , Caro, HN. (1996). Cell signalling by inositol phosphoglycans from different species. Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 115(2): 223-241 (PMID: 8939003) Abstract
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90.- Sanz, C , Leon, Y, Garcia-Gil, M, Varela-Nieto, I . (1996). Role of Raf kinases during inner ear development. Int. J. Dev. Biol. Suppl 1: 83S-84S (PMID: 9087707)
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91.- León, Y , Vazquez, E, Sanz, C , Vega, JA, Mato, JM , Giraldez, F, Represa, J, Varela-Nieto, I . (1995). Insulin-like growth factor-I regulates cell proliferation in the developing inner ear, activating glycosyl-phosphatidylinositol hydrolysis and Fos expression. Endocrinology. 136(8): 3494-3503 (PMID: 7628386) Abstract
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92.- Leon, Y, Sanz, C , Varela-Nieto, I . (1995). Intracellular mediators of insulin-like growth factor I during otic vesicle development. Biochem. Soc. Trans. 23(2): 185S (PMID: 7672208)
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93.- Clemente, R, Jones, DR, Ochoa, P , Romero, G, Mato, JM , Varela-Nieto, I . (1995). Role of glycosyl-phosphatidylinositol hydrolysis as a mitogenic signal for epidermal growth factor. Cell. Signal. 7(4): 411-421 (PMID: 8527310) Abstract
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94.- Jones, DR, Clemente, R, Varela-Nieto, I . (1995). Signalling at the epidermal growth factor receptor: role of glycosylphosphatidylinositol hydrolysis. Biochem. Soc. Trans. 23(2): 174S (PMID: 7672200)
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95.- Zapata, A, León, Y , Mato, JM , Varela-Nieto, I , Penadés, S, Martín-Lomas, M. (1994). Synthesis and investigation of the possible insulin-like activity of 1D-4-O- and 1D-6-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-myo-inositol 1-phosphate and 1D-6-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-myo-inositol 1,2-(cyclic phosphate). Carbohydr. Res. 264(1): 21-31 (PMID: 8001018) Abstract
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96.- Avila, MA, Clemente, R, Varela-Nieto, I . (1994). Mannosamine is an unspecific inhibitor of glycosyl-phosphatidylinositol biosynthesis in T-lymphocytes. Biochem. Soc. Trans. 22(1): 11S (PMID: 8206201)
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97.- Represa, J, Avila, MA, Romero, G, Mato, JM , Giraldez, F, Varela-Nieto, I . (1993). Brain-derived neurotrophic factor and neurotrophin-3 induce cell proliferation in the cochleovestibular ganglion through a glycosyl-phosphatidylinositol signaling system. Dev. Biol. 159(1): 257-265 (PMID: 8365564) Abstract
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98.- Avila, MA, Varela-Nieto, I , Romero, G, Mato, JM , Giraldez, F, Van De Water, TR, Represa, J. (1993). Brain-derived neurotrophic factor and neurotrophin-3 support the survival and neuritogenesis response of developing cochleovestibular ganglion neurons. Dev. Biol. 159(1): 266-275 (PMID: 8365565) Abstract
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99.- Vasta, V, Bruni, P, Clemente, R, Vannini, F, Ochoa, P , Romero, G, Farnararo, M, Varela-Nieto, I . (1992). Role of the glycosylphosphatidylinositol/inositol phosphoglycan system in human fibroblast proliferation. Exp. Cell Res. 200(2): 439-443 (PMID: 1374038) Abstract
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100.- Avila, MA, Clemente, R, Varela-Nieto, I . (1992). A phosphatidylinositol-linkage-deficient T-cell mutant contains insulin-sensitive glycosyl-phosphatidylinositol. Biochem. J. 282 ( Pt 3): 681-686 (PMID: 1532490) Abstract
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101.- Bruni, P, Vasta, V, Berti, L, Avila, MA, Farnararo, M, Varela-Nieto, I . (1991). An inositol phosphoglycan stimulates glycolysis in human platelets. Biochem. Biophys. Res. Commun. 180(2): 1041-1047 (PMID: 1835382) Abstract
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102.- Represa, J, Avila, MA, Miner, C, Giraldez, F, Romero, G, Clemente, R, Mato, JM , Varela-Nieto, I . (1991). Glycosyl-phosphatidylinositol/inositol phosphoglycan: a signaling system for the low-affinity nerve growth factor receptor. Proc. Natl. Acad. Sci. U.S.A. 88(18): 8016-8019 (PMID: 1654553) Abstract
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103.- Alvarez, L , Avila, MA, Mato, JM , Castaño, JG, Varela-Nieto, I . (1991). Insulin-like effects of inositol phosphate-glycan on messenger RNA expression in rat hepatocytes. Mol. Endocrinol. 5(8): 1062-1068 (PMID: 1719385) Abstract
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104.- Varela-Nieto, I , Represa, J, Avila, MA, Miner, C, Mato, JM , Giraldez, F. (1991). Inositol phospho-oligosaccharide stimulates cell proliferation in the early developing inner ear. Dev. Biol. 143(2): 432-435 (PMID: 1991566) Abstract
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105.- Villalba, M, Varela, I , Mérida, I, Pajares, MA , Martínez del Pozo, A, Mato, JM . (1985). Modulation by the ratio S-adenosylmethionine/S-adenosylhomocysteine of cyclic AMP-dependent phosphorylation of the 50 kDa protein of rat liver phospholipid methyltransferase. Biochim. Biophys. Acta. 847(3): 273-279 (PMID: 2998482) Abstract
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106.- Pajares, MA , Alemany, S , Varela, I , Marin Cao, D, Mato, JM . (1984). Purification and photoaffinity labelling of lipid methyltransferase from rat liver. Biochem. J. 223(1): 61-66 (PMID: 6497846) Abstract
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107.- Varela, I , Mérida, I, Pajares, M , Villalba, M, Mato, JM . (1984). Activation of partially purified rat liver lipid methyltransferase by phosphorylation. Biochem. Biophys. Res. Commun. 122(3): 1065-1070 (PMID: 6332623) Abstract
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108.- Mato, JM , Alvarez Chiva, V, Marín Cao, D, Varela, I , García Gil, M, Alemany, S . (1983). [Hormonal regulation of the synthesis of phosphatidylcholine by transmethylation]. Rev Clin Esp. 171(1): 7-10 (PMID: 6658087)
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109.- Alemany, S , Varela, I , Mato, JM . (1982). Inhibition of phosphatidylcholine synthesis by vasopressin and angiotensin in rat hepatocytes. Biochem. J. 208(2): 453-457 (PMID: 6818955) Abstract
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110.- Alemany, S , Varela, I , Harper, JF, Mato, JM . (1982). Calmodulin regulation of phospholipid and fatty acid methylation by rat liver microsomes. J. Biol. Chem. 257(16): 9249-9251 (PMID: 6809733) Abstract
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111.- Alemany, S , Varela, I , Mato, JM . (1981). Stimulation by vasopressin and angiotensin of phospholipid methyltransferase in isolated rat hepatocytes. FEBS Lett. 135(1): 111-114 (PMID: 6797839)
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