Publications
Articles Published in   Benilde Jiménez Cuenca   

1.- Tiana, M , Acosta-Iborra, B , Hernández, R , Galiana, C , Fernández-Moreno, MÁ , Jimenez, B , Del Peso, L . (2020). Metabolic labeling of RNA uncovers the contribution of transcription and decay rates on hypoxia-induced changes in RNA levels. RNA. 26(8): 1006-1022 (PMID: 32295863) Abstract
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2.- Acosta-Iborra, B , Tiana, M , Maeso-Alonso, L, Hernández-Sierra, R , Herranz, G , Santamaria, A , Rey, C , Luna, R , Puente-Santamaria, L , Marques, MM, Marin, MC, Del Peso, L , Jiménez, B . (2020). Hypoxia compensates cell cycle arrest with progenitor differentiation during angiogenesis. FASEB J. (PMID: 32223018) Abstract
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3.- Tiana, M , Acosta-Iborra, B , Puente-Santamaría, L , Hernansanz-Agustin, P , Worsley-Hunt, R, Masson, N, García-Rio, F, Mole, D, Ratcliffe, P, Wasserman, WW, Jimenez, B , Del Peso, L . (2018). The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia. Nucleic Acids Res. 46(1): 120-133 (PMID: 29059365) Abstract
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4.- Roche, O, Deguiz, ML, Tiana, M, Galiana-Ribote, C, Martinez-Alcazar, D, Rey-Serra, C, Ranz-Ribeiro, B, Casitas, R, Galera, R, Fernández-Navarro, I, Sánchez-Cuéllar, S, Bernard, V, Ancochea, J, Wasserman, WW, García-Rio, F, Jimenez, B , Del Peso, L . (2016). Identification of non-coding genetic variants in samples from hypoxemic respiratory disease patients that affect the transcriptional response to hypoxia. Nucleic Acids Res. (PMID: 27625398) Abstract
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5.- Nwani, NG, Deguiz, ML, Jimenez, B , Vinokour, E, Dubrovskyi, O, Ugolkov, A, Mazar, AP, Volpert, OV. (2016). Melanoma cells block PEDF production in fibroblasts to induce the tumor-promoting phenotype of cancer-associated fibroblasts. Cancer Res. (PMID: 26921338) Abstract
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6.- Jiménez, B , Tiana, M, Del Peso, L . (2015). lnc RNAs, hypoxia and metastasis. Oncoscience. 2(10): 795-796 (PMID: 26682249)
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7.- Jiménez Cuenca, B , Fernández-Barral, A , Orgaz, JL . (2015). Microphthalmia-Associated Transcription Factor: A Central Regulator of Pigment Epithelium-Derived Factor Controlling Human Melanoma Progression. Am. J. Pathol. 185(7): 2069-2070 (PMID: 26093986)
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8.- Gómez-Maldonado, L, Tiana, M, Roche, O, Prado-Cabrero, A, Jensen, L, Fernandez-Barral, A, Guijarro-Muñoz, I, Favaro, E, Moreno-Bueno, G , Sanz, L, Aragones, J, Harris, A, Volpert, O, Jimenez, B , del Peso, L . (2015). EFNA3 long noncoding RNAs induced by hypoxia promote metastatic dissemination. Oncogene. 34(20): 2609-2620 (PMID: 25023702) Abstract
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9.- Aguilera, Ó, González-Sancho, JM , Zazo, S, Rincón, R, Fernández, AF, Tapia, O, Canals, F, Morte, B , Calvanese, V, Orgaz, JL , Niell, N , Aguilar, S, Freije, JM, Graña, O, Pisano, DG, Borrero, A, Martínez-Useros, J, Jiménez, B , Fraga, MF, García-Foncillas, J, López-Otín, C, Lafarga, M, Rojo, F, Muñoz, A . (2015). Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer. Oncotarget. 6(8): 5903-5917 (PMID: 25788273) Abstract
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10.- Menéndez, C , Adrados, I , Fernández-Barral, A , Jiménez, B , Flores, JM, Cañamero, M, Fuchtbauer, EM, Beermann, F, Palmero, I . (2014). Increased melanoma formation and dissemination in TyrNRas mice deficient in the tumor suppressor Ing1. Pigment Cell Melanoma Res. 27(4): 674-677 (PMID: 24655373)
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11.- Fernández-Barral, A , Orgaz, JL , Baquero, P, Ali, Z, Moreno, A , Tiana, M, Gómez, V, Riveiro-Falkenbach, E, Cañadas, C, Zazo, S, Bertolotto, C, Davidson, I, Rodríguez-Peralto, JL, Palmero, I , Rojo, F, Jensen, LD, del Peso, L , Jiménez, B . (2014). Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma. Neoplasia. 16(6): 529-542 (PMID: 25030625) Abstract
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12.- Bargiela-Iparraguirre, J , Prado-Marchal, L, Pajuelo-Lozano, N, Jiménez, B , Perona, R , Sánchez-Pérez, I . (2014). Mad2 and BubR1 modulates tumourigenesis and paclitaxel response in MKN45 gastric cancer cells. Cell Cycle. 13(22): 3590-3601 (PMID: 25483095) Abstract
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13.- Baquero, P, Sánchez-Hernández, I, Jiménez-Mora, E, Orgaz, JL , Jiménez, B , Chiloeches, A. (2013). (V600E)BRAF promotes invasiveness of thyroid cancer cells by decreasing E-cadherin expression through a Snail-dependent mechanism. Cancer Lett. 335(1): 232-241 (PMID: 23435375) Abstract
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14.- Bienes-Martínez, R, Ordóñez, A, Feijoo-Cuaresma, M, Corral-Escariz, M, Mateo, G, Stenina, O, Jiménez, B , Calzada, MJ. (2012). Autocrine stimulation of clear-cell renal carcinoma cell migration in hypoxia via HIF-independent suppression of thrombospondin-1. Sci Rep. 2: 788 (PMID: 23145312) Abstract
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15.- Fernández-Barral, A , Orgaz, JL , Gomez, V, del Peso, L , Calzada, MJ, Jiménez, B . (2012). Hypoxia negatively regulates antimetastatic PEDF in melanoma cells by a hypoxia inducible factor-independent, autophagy dependent mechanism. PLoS ONE. 7(3): e32989 (PMID: 22457728) Abstract
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16.- Martinez-Poveda, B, Gomez, V, Alcaide-German, M , Perruca, S , Vazquez, S, Alba, LE, Casanovas, O, Garcia-Bermejo, ML, Peso, L , Jimenez, B . (2011). Non-invasive monitoring of hypoxia-inducible factor activation by optical imaging during antiangiogenic treatment in a xenograft model of ovarian carcinoma. Int. J. Oncol. 39(3): 543-552 (PMID: 21667025) Abstract
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17.- Orgaz, JL , Benguria, A, Sanchez-Martinez, C , Ladhani, O, Volpert, OV, Jimenez, B . (2011). Changes in the gene expression profile of A375 human melanoma cells induced by overexpression of multifunctional pigment epithelium-derived factor. Melanoma Res. 21(4): 285-297 (PMID: 21673604) Abstract
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18.- Ladhani, O, Sánchez-Martinez, C, Orgaz, JL , Jimenez, B , Volpert, OV. (2011). Pigment epithelium-derived factor blocks tumor extravasation by suppressing amoeboid morphology and mesenchymal proteolysis. Neoplasia. 13(7): 633-642 (PMID: 21750657) Abstract
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19.- Moncho-Amor, V , Ibañez de Cáceres, I , Bandres, E, Martínez-Poveda, B , Orgaz, JL , Sánchez-Pérez, I , Zazo, S, Rovira, A, Albanell, J, Jiménez, B , Rojo, F, Belda-Iniesta, C , García-Foncillas, J, Perona, R . (2011). DUSP1/MKP1 promotes angiogenesis, invasion and metastasis in non-small-cell lung cancer. Oncogene. 30(6): 668-678 (PMID: 20890299) Abstract
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20.- Moreno, A , Palacios, A, Orgaz, JL , Jimenez, B , Blanco, FJ, Palmero, I . (2010). Functional impact of cancer-associated mutations in the tumor suppressor protein ING4. Carcinogenesis. 31(11): 1932-1938 (PMID: 20705953) Abstract
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21.- Orgaz, JL , Ladhani, O, Hoek, KS, Fernández-Barral, A , Mihic, D, Aguilera, O , Seftor, EA, Bernad, A, Rodríguez-Peralto, JL, Hendrix, MJ, Volpert, OV, Jiménez, B . (2009). 'Loss of pigment epithelium-derived factor enables migration, invasion and metastatic spread of human melanoma'. Oncogene. 28(47): 4147-4161 (PMID: 19767774) Abstract
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22.- Orgaz, JL , Martínez-Poveda, B , Fernández-García, NI , Jiménez, B . (2008). Following up tumour angiogenesis: from the basic laboratory to the clinic. Clin Transl Oncol. 10(8): 468-477 (PMID: 18667377) Abstract
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23.- Pendás-Franco, N , García, JM , Peña, C, Valle, N , Pálmer, HG , Heinäniemi, M, Carlberg, C, Jiménez, B , Bonilla, F, Muñoz, A , González-Sancho, JM . (2008). DICKKOPF-4 is induced by TCF/beta-catenin and upregulated in human colon cancer, promotes tumour cell invasion and angiogenesis and is repressed by 1alpha,25-dihydroxyvitamin D3. Oncogene. 27(32): 4467-4477 (PMID: 18408752) Abstract
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24.- Fernandez-Garcia, NI , Volpert, OV, Jimenez, B . (2007). Pigment epithelium-derived factor as a multifunctional antitumor factor. J. Mol. Med. 85(1): 15-22 (PMID: 17106733) Abstract
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25.- Fernandez-Garcia, NI , Palmer, HG , Garcia, M, Gonzalez-Martin, A , del Rio, M, Barettino, D , Volpert, O, Muñoz, A , Jimenez, B . (2005). 1alpha,25-Dihydroxyvitamin D3 regulates the expression of Id1 and Id2 genes and the angiogenic phenotype of human colon carcinoma cells. Oncogene. 24(43): 6533-6544 (PMID: 16007183) Abstract
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26.- Garcia, M, Fernandez-Garcia, NI , Rivas, V, Carretero, M, Escamez, MJ, Gonzalez-Martin, A , Medrano, EE, Volpert, O, Jorcano, JL, Jimenez, B , Larcher, F, Del Rio, M. (2004). Inhibition of xenografted human melanoma growth and prevention of metastasis development by dual antiangiogenic/antitumor activities of pigment epithelium-derived factor. Cancer Res. 64(16): 5632-5642 (PMID: 15313901) Abstract
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27.- Caelles, C , Bruna, A, Morales, M, González-Sancho, JM , González, MV , Jiménez, B , Muñoz, A . (2002). Glucocorticoid receptor antagonism of AP-1 activity by inhibition of MAPK family. Ernst Schering Res. Found. Workshop. (40): 131-152 (PMID: 12355714)
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28.- Reiher, FK, Volpert, OV, Jimenez, B , Crawford, SE, Dinney, CP, Henkin, J, Haviv, F, Bouck, NP, Campbell, SC. (2002). Inhibition of tumor growth by systemic treatment with thrombospondin-1 peptide mimetics. Int. J. Cancer. 98(5): 682-689 (PMID: 11920636) Abstract
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29.- Jiménez, B , Volpert, OV. (2001). Mechanistic insights on the inhibition of tumor angiogenesis. J. Mol. Med. 78(12): 663-672 (PMID: 11434719) Abstract
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30.- Jiménez, B , Volpert, OV, Reiher, F, Chang, L, Muñoz, A , Karin, M, Bouck, N. (2001). c-Jun N-terminal kinase activation is required for the inhibition of neovascularization by thrombospondin-1. Oncogene. 20(26): 3443-3448 (PMID: 11423995) Abstract
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31.- González, MV , Jiménez, B , Berciano, MT, González-Sancho, JM , Caelles, C , Lafarga, M, Muñoz, A . (2000). Glucocorticoids antagonize AP-1 by inhibiting the Activation/phosphorylation of JNK without affecting its subcellular distribution. J. Cell Biol. 150(5): 1199-1208 (PMID: 10974006) Abstract
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32.- Jiménez, B , Volpert, OV, Crawford, SE, Febbraio, M, Silverstein, RL, Bouck, N. (2000). Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1. Nat. Med. 6(1): 41-48 (PMID: 10613822) Abstract
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33.- González, MV , González-Sancho, JM , Caelles, C , Munoz, A , Jiménez, B . (1999). Hormone-activated nuclear receptors inhibit the stimulation of the JNK and ERK signalling pathways in endothelial cells. FEBS Lett. 459(2): 272-276 (PMID: 10518034) Abstract
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34.- Gillis, P, Savla, U, Volpert, OV, Jimenez, B , Waters, CM, Panos, RJ, Bouck, NP. (1999). Keratinocyte growth factor induces angiogenesis and protects endothelial barrier function. J. Cell. Sci. 112 ( Pt 12): 2049-2057 (PMID: 10341222) Abstract
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35.- Lucas, R, Holmgren, L, Garcia, I, Jimenez, B , Mandriota, SJ, Borlat, F, Sim, BK, Wu, Z, Grau, GE, Shing, Y, Soff, GA, Bouck, N, Pepper, MS. (1998). Multiple forms of angiostatin induce apoptosis in endothelial cells. Blood. 92(12): 4730-4741 (PMID: 9845539) Abstract
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36.- Esteve, P , Embade, N , Perona, R , Jiménez, B , del Peso, L , León, J, Arends, M, Miki, T, Lacal, JC . (1998). Rho-regulated signals induce apoptosis in vitro and in vivo by a p53-independent, but Bcl2 dependent pathway. Oncogene. 17(14): 1855-1869 (PMID: 9778052) Abstract
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37.- Carnero, A, Jiménez, B . (1995). Effect of microinjection of rap 2A point mutant proteins on maturation and mottling in Xenopus oocytes. Biochem. Biophys. Res. Commun. 216(3): 748-754 (PMID: 7488189) Abstract
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38.- Jiménez, B , del Peso, L , Montaner, S , Esteve, P , Lacal, JC . (1995). Generation of phosphorylcholine as an essential event in the activation of Raf-1 and MAP-kinases in growth factors-induced mitogenic stimulation. J. Cell. Biochem. 57(1): 141-149 (PMID: 7721953) Abstract
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39.- Carnero, A, Jiménez, B , Lacal, JC . (1994). Progesterone but not ras requires MPF for in vivo activation of MAPK and S6 KII: MAPK is an essential conexion point of both signaling pathways. J. Cell. Biochem. 55(4): 465-476 (PMID: 7962177) Abstract
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40.- Cuadrado, A , Carnero, A, Dolfi, F, Jiménez, B , Lacal, JC . (1993). Phosphorylcholine: a novel second messenger essential for mitogenic activity of growth factors. Oncogene. 8(11): 2959-2968 (PMID: 8414498) Abstract
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41.- Mollinedo, F, Perez-Sala, D, Gajate, C, Jimenez, B , Rodriguez, P, Lacal, JC . (1993). Localization of rap1 and rap2 proteins in the gelatinase-containing granules of human neutrophils. FEBS Lett. 326(1-3): 209-214 (PMID: 8391995) Abstract
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42.- Perona, R , Esteve, P , Jiménez, B , Ballestero, RP, Ramón y Cajal, S, Lacal, JC . (1993). Tumorigenic activity of rho genes from Aplysia californica. Oncogene. 8(5): 1285-1292 (PMID: 8479750) Abstract
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43.- Schwandner, WR, Jiménez, B , Schwartz, A, Weijer, CJ, Behrens, M, Mazón, MJ , Fernández-Renart, M . (1993). Chemotactic stimulation of aggregation-stage Dictyostelium cells induces rapid changes in energy metabolism, as measured by succinic thiokinase phosphorylation. Biochim. Biophys. Acta. 1176(1-2): 175-182 (PMID: 8384004) Abstract
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44.- Jimenez, B , Pizon, V, Lerosey, I, Béranger, F, Tavitian, A, de Gunzburg, J. (1991). Effects of the ras-related rap2 protein on cellular proliferation. Int. J. Cancer. 49(3): 471-479 (PMID: 1833345) Abstract
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45.- Jiménez, B , Pestaña, A , Fernandez-Renart, M. (1989). A phospholipid-stimulated protein kinase from Dictyostelium discoideum. Biochem. J. 260(2): 557-561 (PMID: 2764888) Abstract
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46.- Jímenez, B , Van Lookeren Campagne, MM, Pestaña, A , Fernández-Renart, M . (1988). Regulation of diacylglycerol kinase in the transition from quiescence to proliferation in Dictyostelium discoideum. Biochem. Biophys. Res. Commun. 150(1): 118-125 (PMID: 2827662) Abstract
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47.- Jímenez, B , Fernandez-Renart, M, Pestaña, A . (1986). Changes in the plasma membrane ATPase activity in relationship to cell proliferation in Dictyostelium. Biochem. Biophys. Res. Commun. 141(3): 1092-1098 (PMID: 2880581) Abstract
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48.- Agullo, L, Jimenez, B , Aragón, C, Giménez, C. (1986). Beta-alanine transport in synaptic plasma membrane vesicles from rat brain. Efflux, exchange and stoichiometry. Eur. J. Biochem. 159(3): 611-617 (PMID: 3093232) Abstract
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