Moreno, A.; Soleto, I.; García-Sanz, P.; Moreno-Bueno, G.; Palmero, I. "ING4 regulates a secretory phenotype in primary fibroblasts with dual effects on cell proliferation and tumor growth.". Oncogene. (): . (2013). (PMID: 23604125).
Romero-Pérez, L.; Castilla, M...; López-García, M...; Díaz-Martín, J.; Biscuola, M.; Ramiro-Fuentes, S.; Oliva, E.; Matias-Guiu, X.; Prat, J.; Cano, A.; Moreno-Bueno, G.; Palacios, J. "Molecular events in endometrial carcinosarcomas and the role of high mobility group AT-hook 2 in endometrial carcinogenesis.". Hum. Pathol.. 44(2): 244-254. (2013). (PMID: 22974476).
Ocaña, O.H.; Córcoles, R.; Fabra, A.; Moreno-Bueno, G.; Acloque, H.; Vega, S.; Barrallo-Gimeno, A.; Cano, A.; Nieto, M.A. "Metastatic colonization requires the repression of the epithelial-mesenchymal transition inducer Prrx1.". Cancer Cell. 22(6): 709-724. (2012). (PMID: 23201163).
Cano, A.; Santamaría, P.G.; Moreno-Bueno, G. "LOXL2 in epithelial cell plasticity and tumor progression.". Future Oncol. 8(9): 1095-1108. (2012). (PMID: 23030485).
Durán-Prado, M.; Gahete, M.D.; Hergueta-Redondo, M.; Martínez-Fuentes, A.J.; Córdoba-Chacón, J.; Palacios, J.; Gracia-Navarro, F.; Moreno-Bueno, G.; Malagón, M.M.; Luque, R.M.; Castaño, J.P. "The new truncated somatostatin receptor variant sst5TMD4 is associated to poor prognosis in breast cancer and increases malignancy in MCF-7 cells.". Oncogene. 31(16): 2049-2061. (2012). (PMID: 21927030).
Gahete, M.D.; Córdoba-Chacón, J.; Hergueta-Redondo, M.; Martínez-Fuentes, A.J.; Kineman, R.D.; Moreno-Bueno, G.; Luque, R.M.; Castaño, J.P. "A novel human ghrelin variant (In1-ghrelin) and ghrelin-O-acyltransferase are overexpressed in breast cancer: potential pathophysiological relevance.". PLoS ONE. 6(8): . (2011). (PMID: 21829727).
Llobet, D.; Eritja, N.; Domingo, M.; Bergada, L.; Mirantes, C.; Santacana, M.; Pallares, J.; Macià, A.; Yeramian, A.; Encinas, M.; Moreno-Bueno, G.; Palacios, J.; Lewis, R.E.; Matias-Guiu, X.; Dolcet, X. "KSR1 is overexpressed in endometrial carcinoma and regulates proliferation and TRAIL-induced apoptosis by modulating FLIP levels.". Am. J. Pathol.. 178(4): 1529-1543. (2011). (PMID: 21435442).
Abad, M.; Moreno, A.; Palacios, A.; Narita, M.; Blanco, F.; Moreno-Bueno, G.; Narita, M.; Palmero, I. "The tumor suppressor ING1 contributes to epigenetic control of cellular senescence.". Aging Cell. 10(1): 158-171. (2011). (PMID: 21078114).
Castilla, M...; Moreno-Bueno, G.; Romero-Pérez, L.; Van De Vijver, K.; Biscuola, M.; López-García, M...; Prat, J.; Matías-Guiu, X.; Cano, A.; Oliva, E.; Palacios, J. "Micro-RNA signature of the epithelial-mesenchymal transition in endometrial carcinosarcoma.". J. Pathol.. 223(1): 72-80. (2011). (PMID: 21125666).
Caffarel, M.M.; Andradas, C.; Mira, E.; Pérez-Gómez, E.; Cerutti, C.; Moreno-Bueno, G.; Flores, J.M.; García-Real, I.; Palacios, J.; Mañes, S.; Guzmán, M.; Sánchez, C. "Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition.". Mol. Cancer. 9(): 196. (2010). (PMID: 20649976).
Castilla, M.A.; Moreno-Bueno, G.; Romero-Pérez, L.; De Vijver, K.V.; Biscuola, M.; López-García, M.A.; Prat, J.; Matías-Guiu, X.; Cano, A.; Oliva, E.; Palacios, J. "Micro-RNA signature of the epithelial-mesenchymal transition in endometrial carcinosarcoma.". J. Pathol.. (): . (2010). (PMID: 21038317).
Sarrió, D.; Palacios, J.; Hergueta-Redondo, M.; Gómez-López, G.; Cano, A.; Moreno-Bueno, G. "Functional characterization of E- and P-cadherin in invasive breast cancer cells.". BMC Cancer. 9(): 74. (2009). (PMID: 19257890).
Geyer, J.T.; López-García, M.A.; Sánchez-Estevez, C.; Sarrió, D.; Moreno-Bueno, G.; Franceschetti, I.; Palacios, J.; Oliva, E. "Pathogenetic pathways in ovarian endometrioid adenocarcinoma: a molecular study of 29 cases.". Am. J. Surg. Pathol.. 33(8): 1157-1163. (2009). (PMID: 19542870).
Fernandez-Marcos, P.J.; Abu-Baker, S.; Joshi, J.; Galvez, A.; Castilla, E.A.; Cañamero, M.; Collado, M.; Saez, C.; Moreno-Bueno, G.; Palacios, J.; Leitges, M.; Serrano, M.; Moscat, J.; Diaz-Meco, M.T. "Simultaneous inactivation of Par-4 and PTEN in vivo leads to synergistic NF-kappaB activation and invasive prostate carcinoma.". Proc. Natl. Acad. Sci. U.S.A.. 106(31): 12962-12967. (2009). (PMID: 19470463).
Fabre-Guillevin, E.; Malo, M.; Cartier-Michaud, A.; Peinado, H.; Moreno-Bueno, G.; Vallée, B.; Lawrence, D.A.; Palacios, J.; Cano, A.; Barlovatz-Meimon, G.; Charrière-Bertrand, C. "PAI-1 and functional blockade of SNAI1 in breast cancer cell migration.". Breast Cancer Res.. 10(6): . (2008). (PMID: 19055748).
Moreno-Bueno, G.; Portillo, F.; Cano, A. "Transcriptional regulation of cell polarity in EMT and cancer.". Oncogene. 27(55): 6958-6969. (2008). (PMID: 19029937).
Durán, M.C.; Vega, F.; Moreno-Bueno, G.; Artiga, M.J.; Sanchez, L.; Palacios, J.; Ridley, A.; Timms, J.F. "Characterisation of tumoral markers correlated with ErbB2 (HER2/Neu) overexpression and metastasis in breast cancer.". Proteomics Clin Appl. 2(9): 1313-1326. (2008). (PMID: 21136925).
Turbiner, J.; Moreno-Bueno, G.; Dahiya, S.; Sánchez-Estevez, C.; Hardisson, D.; Prat, J.; Oliva, E.; Palacios, J. "Clinicopathological and molecular analysis of endometrial carcinoma associated with tamoxifen.". Mod. Pathol.. 21(8): 925-936. (2008). (PMID: 18500270).
Caffarel, M.M.; Moreno-Bueno, G.; Cerutti, C.; Palacios, J.; Guzman, M.; Mechta-Grigoriou, F.; Sanchez, C. "JunD is involved in the antiproliferative effect of Delta9-tetrahydrocannabinol on human breast cancer cells.". Oncogene. 27(37): 5033-5044. (2008). (PMID: 18454173).
Olmeda, D.; Montes, A.; Moreno-Bueno, G.; Flores, J.M.; Portillo, F.; Cano, A. "Snai1 and Snai2 collaborate on tumor growth and metastasis properties of mouse skin carcinoma cell lines.". Oncogene. 27(34): 4690-4701. (2008). (PMID: 18408755).
Sarrió, D.; Rodriguez-Pinilla, S.M.; Hardisson, D.; Cano, A.; Moreno-Bueno, G.; Palacios, J. "Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype.". Cancer Res.. 68(4): 989-997. (2008). (PMID: 18281472).
Olmeda, D.; Moreno-Bueno, G.; Flores, J.M.; Fabra, A.; Portillo, F.; Cano, A. "SNAI1 is required for tumor growth and lymph node metastasis of human breast carcinoma MDA-MB-231 cells.". Cancer Res.. 67(24): 11721-11731. (2007). (PMID: 18089802).
Hernández-Vargas, H.; von Kobbe, C.; Sánchez-Estévez, C.; Julián-Tendero, M.; Palacios, J.; Moreno-Bueno, G. "Inhibition of paclitaxel-induced proteasome activation influences paclitaxel cytotoxicity in breast cancer cells in a sequence-dependent manner.". Cell Cycle. 6(21): 2662-2668. (2007). (PMID: 17912036).
Rodríguez-Pinilla, S.M.; Sarrió, D.; Honrado, E.; Moreno-Bueno, G.; Hardisson, D.; Calero, F.; Benítez, J.; Palacios, J. "Vimentin and laminin expression is associated with basal-like phenotype in both sporadic and BRCA1-associated breast carcinomas.". J. Clin. Pathol.. 60(9): 1006-1012. (2007). (PMID: 17105822).
Hernández-Vargas, H.; Palacios, J.; Moreno-Bueno, G. "Molecular profiling of docetaxel cytotoxicity in breast cancer cells: uncoupling of aberrant mitosis and apoptosis.". Oncogene. 26(20): 2902-2913. (2007). (PMID: 17099726).
Hernández-Vargas, H.; Rodríguez-Pinilla, S.M.; Julián-Tendero, M.; Sánchez-Rovira, P.; Cuevas, C.; Antón, A.; Ríos, M.J.; Palacios, J.; Moreno-Bueno, G. "Gene expression profiling of breast cancer cells in response to gemcitabine: NF-kappaB pathway activation as a potential mechanism of resistance.". Breast Cancer Res. Treat.. 102(2): 157-172. (2007). (PMID: 17039268).
Rodriguez-Pinilla, S.M.; Sarrio, D.; Moreno-Bueno, G.; Rodriguez-Gil, Y.; Martinez, M.A.; Hernandez, L.; Hardisson, D.; Reis-Filho, J.S.; Palacios, J. "Sox2: a possible driver of the basal-like phenotype in sporadic breast cancer.". Mod. Pathol.. 20(4): 474-481. (2007). (PMID: 17334350).
Rodríguez-Pinilla, S.M.; Rodríguez-Gil, Y.; Moreno-Bueno, G.; Sarrió, D.; Martín-Guijarro, M.d.e.l. .C.; Hernandez, L.; Palacios, J. "Sporadic invasive breast carcinomas with medullary features display a basal-like phenotype: an immunohistochemical and gene amplification study.". Am. J. Surg. Pathol.. 31(4): 501-508. (2007). (PMID: 17414096).
Hernández-Vargas, H.; Palacios, J.; Moreno-Bueno, G. "Telling cells how to die: docetaxel therapy in cancer cell lines.". Cell Cycle. 6(7): 780-783. (2007). (PMID: 17377494).
Moreno-Bueno, G.; Fernandez-Marcos, P.J.; Collado, M.; Tendero, M.J.; Rodriguez-Pinilla, S.M.; Garcia-Cao, I.; Hardisson, D.; Diaz-Meco, M.T.; Moscat, J.; Serrano, M.; Palacios, J. "Inactivation of the candidate tumor suppressor par-4 in endometrial cancer.". Cancer Res.. 67(5): 1927-1934. (2007). (PMID: 17332319).
Molina-Arcas, M.; Moreno-Bueno, G.; Cano-Soldado, P.; Hernández-Vargas, H.; Casado, F.J.; Palacios, J.; Pastor-Anglada, M. "Human equilibrative nucleoside transporter-1 (hENT1) is required for the transcriptomic response of the nucleoside-derived drug 5'-DFUR in breast cancer MCF7 cells.". Biochem. Pharmacol.. 72(12): 1646-1656. (2006). (PMID: 16965766).
Moreno-Bueno, G.; Cubillo, E.; Sarrió, D.; Peinado, H.; Rodríguez-Pinilla, S.M.; Villa, S.; Bolós, V.; Jordá, M.; Fabra, A.; Portillo, F.; Palacios, J.; Cano, A. "Genetic profiling of epithelial cells expressing E-cadherin repressors reveals a distinct role for Snail, Slug, and E47 factors in epithelial-mesenchymal transition.". Cancer Res.. 66(19): 9543-9556. (2006). (PMID: 17018611).
Hernández-Vargas, H.; Ballestar, E.; Carmona-Saez, P.; von Kobbe, C.; Bañón-Rodríguez, I.; Esteller, M.; Moreno-Bueno, G.; Palacios, J. "Transcriptional profiling of MCF7 breast cancer cells in response to 5-Fluorouracil: relationship with cell cycle changes and apoptosis, and identification of novel targets of p53.". Int. J. Cancer. 119(5): 1164-1175. (2006). (PMID: 16557594).
Sarrió, D.; Moreno-Bueno, G.; Sánchez-Estévez, C.; Bañón-Rodríguez, I.; Hernández-Cortés, G.; Hardisson, D.; Palacios, J. "Expression of cadherins and catenins correlates with distinct histologic types of ovarian carcinomas.". Hum. Pathol.. 37(8): 1042-1049. (2006). (PMID: 16867867).
Moreno-Bueno, G.; Sanchez-Estevez, C.; Palacios, J.; Hardisson, D.; Shiozawa, T. "Low frequency of BRAF mutations in endometrial and in cervical carcinomas.". Clin. Cancer Res.. 12(12): . (2006). (PMID: 16778116).
Oliva, E.; Sarrió, D.; Brachtel, E.F.; Sánchez-Estévez, C.; Soslow, R.A.; Moreno-Bueno, G.; Palacios, J. "High frequency of beta-catenin mutations in borderline endometrioid tumours of the ovary.". J. Pathol.. 208(5): 708-713. (2006). (PMID: 16429393).
Brachtel, E.F.; Sánchez-Estevez, C.; Moreno-Bueno, G.; Prat, J.; Palacios, J.; Oliva, E. "Distinct molecular alterations in complex endometrial hyperplasia (CEH) with and without immature squamous metaplasia (squamous morules).". Am. J. Surg. Pathol.. 29(10): 1322-1329. (2005). (PMID: 16160475).
Matar, P.; Rojo, F.; Cassia, R.; Moreno-Bueno, G.; Di Cosimo, S.; Tabernero, J.; Guzmán, M.; Rodriguez, S.; Arribas, J.; Palacios, J.; Baselga, J. "Combined epidermal growth factor receptor targeting with the tyrosine kinase inhibitor gefitinib (ZD1839) and the monoclonal antibody cetuximab (IMC-C225): superiority over single-agent receptor targeting.". Clin. Cancer Res.. 10(19): 6487-6501. (2004). (PMID: 15475436).
Moreno-Bueno, G.; Rodríguez-Perales, S.; Sánchez-Estévez, C.; Marcos, R.; Hardisson, D.; Cigudosa, J.C.; Palacios, J. "Molecular alterations associated with cyclin D1 overexpression in endometrial cancer.". Int. J. Cancer. 110(2): 194-200. (2004). (PMID: 15069681).
Sarrió, D.; Pérez-Mies, B.; Hardisson, D.; Moreno-Bueno, G.; Suárez, A.; Cano, A.; Martín-Pérez, J.; Gamallo, C.; Palacios, J. "Cytoplasmic localization of p120ctn and E-cadherin loss characterize lobular breast carcinoma from preinvasive to metastatic lesions.". Oncogene. 23(19): 3272-3283. (2004). (PMID: 15077190).
Moreno-Bueno, G.; Hardisson, D.; Prat, J.; Matías-Guiu, J.; Palacios, J. "Re: Scholten et al. Nuclear beta-catenin is a molecular feature of type I endometrial carcinoma. J Pathol 2003; 201: 460-465.". J. Pathol.. 202(4): 511-512. (2004). (PMID: 15095279).
Cassia, R.; Moreno-Bueno, G.; Rodríguez-Perales, S.; Hardisson, D.; Cigudosa, J.C.; Palacios, J. "Cyclin E gene (CCNE) amplification and hCDC4 mutations in endometrial carcinoma.". J. Pathol.. 201(4): 589-595. (2003). (PMID: 14648662).
Hardisson, D.; Moreno-Bueno, G.; Sánchez, L.; Sarrió, D.; Suárez, A.; Calero, F.; Palacios, J. "Tissue microarray immunohistochemical expression analysis of mismatch repair (hMLH1 and hMSH2 genes) in endometrial carcinoma and atypical endometrial hyperplasia: relationship with microsatellite instability.". Mod. Pathol.. 16(11): 1148-1158. (2003). (PMID: 14614055).
Moreno-Bueno, G.; Sánchez-Estévez, C.; Cassia, R.; Rodríguez-Perales, S.; Díaz-Uriarte, R.; Domínguez, O.; Hardisson, D.; Andujar, M.; Prat, J.; Matias-Guiu, X.; Cigudosa, J.C.; Palacios, J. "Differential gene expression profile in endometrioid and nonendometrioid endometrial carcinoma: STK15 is frequently overexpressed and amplified in nonendometrioid carcinomas.". Cancer Res.. 63(18): 5697-5702. (2003). (PMID: 14522886).
Sarrió, D.; Moreno-Bueno, G.; Hardisson, D.; Sánchez-Estévez, C.; Guo, M.; Herman, J.G.; Gamallo, C.; Esteller, M.; Palacios, J. "Epigenetic and genetic alterations of APC and CDH1 genes in lobular breast cancer: relationships with abnormal E-cadherin and catenin expression and microsatellite instability.". Int. J. Cancer. 106(2): 208-215. (2003). (PMID: 12800196).
Moreno-Bueno, G.; Hardisson, D.; Sarrió, D.; Sánchez, C.; Cassia, R.; Prat, J.; Herman, J.G.; Esteller, M.; Matías-Guiu, X.; Palacios, J. "Abnormalities of E- and P-cadherin and catenin (beta-, gamma-catenin, and p120ctn) expression in endometrial cancer and endometrial atypical hyperplasia.". J. Pathol.. 199(4): 471-478. (2003). (PMID: 12635138).
Moreno-Bueno, G.; Hardisson, D.; Sánchez, C.; Sarrió, D.; Cassia, R.; García-Rostán, G.; Prat, J.; Guo, M.; Herman, J.G.; Matías-Guiu, X.; Esteller, M.; Palacios, J. "Abnormalities of the APC/beta-catenin pathway in endometrial cancer.". Oncogene. 21(52): 7981-7990. (2002). (PMID: 12439748).
Blanco, M.J.; Moreno-Bueno, G.; Sarrio, D.; Locascio, A.; Cano, A.; Palacios, J.; Nieto, M.A. "Correlation of Snail expression with histological grade and lymph node status in breast carcinomas.". Oncogene. 21(20): 3241-3246. (2002). (PMID: 12082640).
Gras, E.; Catasus, L.; Argüelles, R.; Moreno-Bueno, G.; Palacios, J.; Gamallo, C.; Matias-Guiu, X.; Prat, J. "Microsatellite instability, MLH-1 promoter hypermethylation, and frameshift mutations at coding mononucleotide repeat microsatellites in ovarian tumors.". Cancer. 92(11): 2829-2836. (2001). (PMID: 11753956).
Moreno-Bueno, G.; Gamallo, C.; Pérez-Gallego, L.; Contreras, F.; Palacios, J. "beta-catenin expression in pilomatrixomas. Relationship with beta-catenin gene mutations and comparison with beta-catenin expression in normal hair follicles.". Br. J. Dermatol.. 145(4): 576-581. (2001). (PMID: 11703283).
Rodríguez-Salas, N.; Palacios, J.; Moreno, G.; de Castro, J.; González-Barón, M.; Gamallo, C. "Correlation of p53 oncoprotein expression with chemotherapy response in small cell lung carcinomas.". Lung Cancer. 34(1): 67-74. (2001). (PMID: 11557115).
Pérez-Gallego, L.; Moreno-Bueno, G.; Sarrió, D.; Suárez, A.; Gamallo, C.; Palacios, J. "Human papillomavirus-16 E6 variants in cervical squamous intraepithelial lesions from HIV-negative and HIV-positive women.". Am. J. Clin. Pathol.. 116(1): 143-148. (2001). (PMID: 11447745).
Gamallo, C.; Moreno-Bueno, G.; Sarrió, D.; Calero, F.; Hardisson, D.; Palacios, J. "The prognostic significance of P-cadherin in infiltrating ductal breast carcinoma.". Mod. Pathol.. 14(7): 650-654. (2001). (PMID: 11454996).
Moreno-Bueno, G.; Gamallo, C.; Pérez-Gallego, L.; de Mora, J.C.; Suárez, A.; Palacios, J. "beta-Catenin expression pattern, beta-catenin gene mutations, and microsatellite instability in endometrioid ovarian carcinomas and synchronous endometrial carcinomas.". Diagn. Mol. Pathol.. 10(2): 116-122. (2001). (PMID: 11385321).
Palacios, J.; Catasús, L.; Moreno-Bueno, G.; Matias-Guiu, X.; Prat, J.; Gamallo, C. "Beta- and gamma-catenin expression in endometrial carcinoma. Relationship with clinicopathological features and microsatellite instability.". Virchows Arch.. 438(5): 464-469. (2001). (PMID: 11407474).
Rodríguez-Salas, N.; Palacios, J.; de Castro, J.; Moreno, G.; González-Barón, M.; Gamallo, C. "Beta-catenin expression pattern in small cell lung cancer: correlation with clinical and evolutive features.". Histol. Histopathol.. 16(2): 353-358. (2001). (PMID: 11332690).
de Castro, J.; Gamallo, C.; Palacios, J.; Moreno-Bueno, G.; Rodríguez, N.; Feliu, J.; González-Barón, M. "beta-catenin expression pattern in primary oesophageal squamous cell carcinoma. Relationship with clinicopathologic features and clinical outcome.". Virchows Arch.. 437(6): 599-604. (2000). (PMID: 11193470).
Moreno-Bueno, G.; Calés, C.; Behrens, M.M.; Fernández-Renart, M. "Isolation and characterization of casein kinase I from Dictyostelium discoideum.". Biochem. J.. 349(Pt 2): 527-537. (2000). (PMID: 10880352).
Gamallo, C.; Palacios, J.; Moreno, G.; Calvo de Mora, J.; Suárez, A.; Armas, A. "beta-catenin expression pattern in stage I and II ovarian carcinomas : relationship with beta-catenin gene mutations, clinicopathological features, and clinical outcome.". Am. J. Pathol.. 155(2): 527-536. (1999). (PMID: 10433945).
Instituto de Investigaciones Biomédicas "Alberto Sols"
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